Bibliography

The CPRD bibliography is updated on a quarterly basis (last update, December 2012).

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Research Papers

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Research Papers - 2013

  1. The use of metformin and the incidence of lung cancer in patients with type 2 diabetes.
    Smiechowski BB, Azoulay L, Yin H, Pollak MN, Suissa S.
    Diabetes Care. 2013 Jan;36(1):124-9.
    PMID:22923670
  2. Temporal trends of Barrett's oesophagus and gastro-oesophageal reflux and related oesophageal cancer over a 10-year period in England and Wales and associated proton pump inhibitor and H2RA prescriptions: a GPRD study.
    Alexandropoulou K, van Vlymen J, Reid F, Poullis A, Kang JY.
    Eur J Gastroenterol Hepatol. 2013 Jan;25(1):15-21.
    PMID: 23022985.
  3. Thromboprophylaxis of elderly patients with AF in the UK: an analysis using the General Practice Research Database (GPRD) 2000-2009.
    Scowcroft AC, Lee S, Mant J.
    Heart. 2013 Jan;99(2):127-32.
    PMID: 23086966.
  4. A study of baseline prevalence and cumulative incidence of comorbidity and extra-articular manifestations in RA and their impact on outcome.
    Norton S, Koduri G, Nikiphorou E, Dixey J, Williams P, Young A.
    Rheumatology (Oxford). 2013 Jan;52(1):99-110.
    PMID: 23086517.
  5. Costs Associated With Treatment of Chronic Low Back Pain: An Analysis of the UK General Practice Research Database.
    Hong J, Reed C, Novick D, Happich M
    Spine (Phila Pa 1976). 2013 Jan 1;38(1):75-82.
    PMID: 23038621.
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Research Papers - 2012

  1. Use of Antidiabetic Agents and the Risk of Pancreatic Cancer: A Case-Control Analysis.
    Bodmer M, Becker C, Meier C, Jick SS, Meier CR.
    Am J Gastroenterol. 2012 Jan 31. doi: 10.1038/ajg.2011.483. [Epub ahead of print]
    PMID: 22290402.
  2. Non-Steroidal Anti-Inflammatory Drugs and The Risk of Clostridium Difficile-Associated Disease.
    Suissa D, Delaney JA, Dial S, Brassard P.
    Br J Clin Pharmacol. 2012 Jan 29. doi: 10.1111/j.1365-2125.2012.04191.x. [Epub ahead of print]
    PMID: 22283873.
  3. Dopamine agonist use and the risk of heart failure.
    Renoux C, Dell'Aniello S, Brophy JM, Suissa S
    Pharmacoepidemiol Drug Saf. 2012 Jan;21(1):34-41. doi:10.1002/pds.2267. Epub 2011 Nov 23.
    PMID: 22109939.
  4. Proton pump inhibitors and histamine-2-receptor antagonists and pancreatic cancer risk: a nested case-control study.
    Bradley MC, Murray LJ, Cantwell MM, Hughes CM.
    Br J Cancer. 2012 Jan 3;106(1):233-9. doi:10.1038/bjc.2011.511. Epub 2011 Nov 22.
    PMID: 22108522.
  5. Extracting diagnoses and investigation results from unstructured text in electronic health records by semi-supervised machine learning.
    Wang Z, Shah AD, Tate AR, Denaxas S, Shawe-Taylor J, Hemingway H.
    PLoS One. 2012;7(1):e30412. Epub 2012 Jan 19.
    PMID: 22276193.
  6. Coding, recording and incidence of different forms of coronary heart disease in primary care.
    Bhattarai N, Charlton J, Rudisill C, Gulliford MC.
    PLoS One. 2012;7(1):e29776. Epub 2012 Jan 19.
    PMID: 22276128.
  7. Quality of INR Control and Outcomes Following Venous Thromboembolism.
    Gallagher AM, de Vries F, Plumb JM, Haß B, Clemens A, van Staa TP.
    Clin Appl Thromb Hemost. 2012 Jan 23. [Epub ahead of print]
    PMID: 22275390.
  8. Jaundice in primary care: a cohort study of adults aged >45 years using electronic medical records.
    Taylor A, Stapley S, Hamilton W.
    Fam Pract. 2012 Jan 13. [Epub ahead of print]
    PMID: 22247287.
  9. Features of childhood cancer in primary care: a population-based nested case-control study.
    Dommett RM, Redaniel MT, Stevens MC, Hamilton W, Martin RM.
    Br J Cancer. 2012 Jan 12. doi: 10.1038/bjc.2011.600.
    PMID: 22240793.
  10. Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study.
    Choi HK, Soriano LC, Zhang Y, Rodríguez LA.
    BMJ. 2012 Jan 12;344:d8190. doi: 10.1136/bmj.d8190.
    PMID: 22240117.
  11. Co-administration of statins with cytochrome P450 3A4 inhibitors in a UK primary care population.
    Bakhai A, Rigney U, Hollis S, Emmas C.
    Pharmacoepidemiol Drug Saf. 2012 Jan 12. doi: 10.1002/pds.2308. [Epub ahead of print]
    PMID: 22237927.
  12. Treatment pathways for patients with atrial fibrillation.
    Hodgkinson JA, Taylor CJ, Hobbs FD.
    Int J Clin Pract. 2012 Jan;66(1):44-52. doi:10.1111/j.1742-1241.2011.02818.x.
    PMID: 22171904.
  13. Pragmatic randomised trials using routine electronic health records: putting them to the test.
    Staa TP, Goldacre B, Gulliford M, Cassell J, Pirmohamed M, Taweel A, Delaney B, Smeeth L.
    BMJ. 2012 Feb 7;344:e55. doi: 10.1136/bmj.e55.
    PMID: 22315246.
  14. Drospirenone- and levonorgestrel-containing oral contraceptives and the risk of gallbladder disease.
    Jick S, Pennap D.
    Contraception. 2012 Feb 9. [Epub ahead of print]
    PMID: 22325114.
  15. Use of metformin is not associated with a decreased risk of colorectal cancer: a case-control analysis.
    Bodmer M, Becker C, Meier C, Jick SS, Meier CR.
    Cancer Epidemiol Biomarkers Prev. 2012 Feb;21(2):280-6. Epub 2011 Dec 16.
    PMID: 22178569.
  16. Suicide risk in primary care patients with major physical diseases: a case-control study.
    Webb RT, Kontopantelis E, Doran T, Qin P, Creed F, Kapur N.
    Arch Gen Psychiatry. 2012 Mar;69(3):256-64.
    PMID: 22393218.
  17. Clinical characteristics and patterns of healthcare utilization in patients with painful neuropathic disorders in UK general practice: a retrospective cohort study.
    Berger A, Sadosky A, Dukes E, Edelsberg J, Oster G.
    BMC Neurol. 2012 Mar 6;12:8.
    PMID: 22394606.
  18. Health service use in families where children enter public care: a nested case control study using the General Practice Research Database.
    Simkiss DE, Spencer NJ, Stallard N, Thorogood M.
    BMC Health Serv Res. 2012 Mar 16;12:65.
    PMID: 22424404.
  19. Healthcare utilization among patients with depression before and after initiating duloxetine in the United Kingdom.
    Shi N, Cao Z, Durden E, Schacht A, Torres A, Happich M.
    J Med Econ. 2012;15(4):672-80.
    PMID: 22390770.
  20. Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database.
    Bhaskaran K, Douglas I, Evans S, van Staa T, Smeeth L
    BMJ. 2012 Apr 24;344:e2697.
    PMID: 22531797.
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  1. Fracture rate in patients with myasthenia gravis: the general practice research database.
    Pouwels S, de Boer A, Javaid MK, Hilton-Jones D, Verschuuren J, Cooper C, Leufkens HG, de Vries F.
    Osteoporos Int. 2012 Apr 25.
    PMID: 22531999.
  2. Incidence, Mortality, and Disease Associations of Pyoderma Gangrenosum in the United Kingdom: A Retrospective Cohort Study.
    Langan SM, Groves RW, Card TR, Gulliford MC.
    J Invest Dermatol. 2012 Apr 26.
    PMID: 22534879.
  3. Comorbidities and Concomitant Medication Use in Men with Prostate Cancer or High Levels of PSA Compared to Matched Controls: A GPRD Analysis.
    Li H, Hodgson E, Watson L, Shukla A, Nelson JJ.
    J Cancer Epidemiol. 2012;2012:291704
    PMID: 22570655.
  4. Risk of tuberculosis in pregnancy: a national, primary care-based cohort and self-controlled case series study.
    Zenner D, Kruijshaar ME, Andrews N, Abubakar I.
    Am J Respir Crit Care Med. 2012 Apr 1;185(7):779-84.
    PMID: 22161161.
  5. Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case-control study.
    Imfeld P, Bodmer M, Jick SS, Meier CR.
    J Am Geriatr Soc. 2012 May;60(5):916-21
    PMID: 22458300.
  6. A study on the epidemiology of rosacea in the U.K.
    Spoendlin J, Voegel JJ, Jick SS, Meier CR.
    Br J Dermatol. 2012 May 5.
    PMID: 22564022.
  7. The Risk of Adverse Outcomes in Association with Use of Testosterone Products: A Cohort Study using the UK-based General Practice Research Database.
    Jick SS, Hagberg KW.
    Br J Clin Pharmacol. 2012 May 11.
    PMID: 22574772.
  8. Hormone replacement therapy is associated with gastro-oesophageal reflux disease: a retrospective cohort study.
    Close H, Mason JM, Wilson D, Hungin AP.
    BMC Gastroenterol. 2012 May 29;12:56.
    PMID: 22642788.
  9. The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study.
    Azoulay L, Yin H, Filion KB, Assayag J, Majdan A, Pollak MN, Suissa S.
    BMJ. 2012 May 30;344:e3645.
    PMID: 22653981.
  10. Pioglitazone and bladder cancer: A propensity score matched cohort study.
    Li W, Macdonald TM, Mackenzie IS.
    Br J Clin Pharmacol. 2012 May 11.
    PMID: 22574756.
  11. The lifetime risk of total hip and kneearthroplasty: results from the UK general practice research database.
    Culliford DJ, Maskell J, Kiran A, Judge A, Javaid MK, Cooper C, Arden NK.
    Osteoarthritis Cartilage. 2012 Jun;20(6):519-24.
    PMID: 22395038.
  12. The risk of pancreatic cancer in symptomatic patients in primary care: a large case-control study using electronic records.
    Stapley S, Peters TJ, Neal RD, Rose PW, Walter FM, Hamilton W.
    Br J Cancer. 2012 Jun 5;106(12):1940-4.
    PMID: 22617126.
  13. Association between appendicectomy in females and subsequent pregnancy rate: a cohort study.
    Wei L, Macdonald T, Shimi S.
    Fertil Steril. 2012 Aug;98(2):401-5.
    PMID: 22683011.
  14. Predictors of Treatment with Duloxetine or Venlafaxine XR among Adult Patients Treated for Depression in Primary Care Practices in the United Kingdom.
    Shi N, Durden E, Torres A, Cao Z, Happich M.
    Depress Res Treat. 2012;2012:815363.
    PMID: 22720149.
  15. A net clinical benefit analysis of warfarin and aspirin on stroke in patients with atrial fibrillation: a nested case-control study.
    Azoulay L, Dell'aniello S, Simon TA, Langleben D, Renoux C, Suissa S.
    BMC Cardiovasc Disord. 2012 Jun 26;12(1):49.
    PMID: 22734842.
  16. Comparison of prescription drug costs in the United States and the United Kingdom, part 2: proton pump inhibitors.
    Jick H, Wilson A, Wiggins P, Chamberlain DP.
    Pharmacotherapy 2012 Jun;32(6):489-92.
    PMID: 22511180.
  17. Incidence of the Pneumoconioses in the United Kingdom General Population between 1997 and 2008.
    Amar RK, Jick SS, Rosenberg D, Maher TM, Meier CR.
    Respiration. 2012 Jun 7.
    PMID: 22678015.
  18. Validity of cancer diagnosis in a primary care database compared with linked cancer registrations in England. Population-based cohort study
    Dregan A, Moller H, Murray-Thomas T, Gulliford MC.
    Cancer Epidemiol. 2012 Jun 21.
    PMID: 22727737.
  19. Causes of death in patients with multiple sclerosis and matched referent subjects: a population-based cohort study.
    Lalmohamed A, Bazelier MT, Van Staa TP, Uitdehaag BM, Leufkens HG, De Boer A,De Vries F.
    Eur J Neurol. 2012 Jul;19(7):1007-14.
    PMID: 22353360.
  20. Trends in antiepileptic drug utilisation in UK primary care 1993-2008: Cohort study using the General Practice Research Database.
    Nicholas JM, Ridsdale L, Richardson MP, Ashworth M, Gulliford MC.
    Seizure. 2012 Jul;21(6):466-70.
    PMID: 22608976.
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  1. An algorithm to identify medical practices common to both the General Practice Research Database and The Health Improvement Network database.
    Cai B, Xu W, Bortnichak E, Watson DJ.
    Pharmacoepidemiol Drug Saf. 2012 Jul;21(7):770-774.
    PMID: 22544805.
  2. Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies
    Lo Re V 3rd, Haynes K, Ming EE, Wood Ives J, Horne LN, Fortier K, Carbonari DM, Hennessy S, Cardillo S, Reese PP, Reddy KR, Margolis D, Apter A, Kimmel SE, Roy J, Freeman CP, Razzaghi H, Holick CN, Esposito DB, Van Staa TP, Bhullar H, Strom BL.
    Pharmacoepidemiol Drug Saf. 2012 Jul 5.
    PMID: 22763953.
  3. Evaluation of Adverse Outcome in Young Women with Polycystic Ovary Syndrome Versus Matched, Reference Controls: A Retrospective, Observational Study.
    Morgan CL, Jenkins-Jones S, Currie CJ, Rees DA.
    J Clin Endocrinol Metab. 2012 Jul 5.
    PMID: 22767635.
  4. Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
    Douglas IJ, Evans SJ, Hingorani AD, Grosso AM, Timmis A, Hemingway H, Smeeth L.
    BMJ. 2012 Jul 10;345:e4388.
    PMID: 22782731.
  5. Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study.
    Mackenzie IS, Macdonald TM, Thompson A, Morant S, Wei L.
    BMJ. 2012 Jul 13;345:e4447.
    PMID: 22797844.
  6. Discontinuation of beta-blockers in cardiovascular disease: UK primary care cohort study.
    Kalra PR, Morley C, Barnes S, Menown I, Kassianos G, Padmanabhan S, Gupta S, Lang CC.
    Int J Cardiol. 2012 Jul 26.
    PMID: 22840685.
  7. Community Care in England: Reducing Socioeconomic Inequalities in Heart Failure.
    Hawkins NM, Scholes S, Bajekal M, Love H, O'Flaherty M, Raine R, Capewell S.
    Circulation. 2012 Jul 26.
    PMID: 22837162.
  8. Impact of Diabetes Duration and Chronic Pancreatitis on the Association between Type 2 Diabetes And Pancreatic Cancer Risk.
    Brodovicz KG, Kou TD, Alexander CM, O'Neill EA, Engel SS, Girman CJ, Goldstein BJ.
    Diabetes Obes Metab. 2012 Jul 25.
    PMID: 22831166.
  9. Epidemiology of clinical body mass index recording in an obese population in primary care: a cohort study.
    Booth HP, Prevost AT, Gulliford MC.
    J Public Health (Oxf). 2012 Jul 24.
    PMID: 22829663.
  10. A retrospective comparison of acute rhinosinusitis outcomes in patients prescribed antibiotics, mometasone furoate nasal spray, or both.
    de Moor C, Reardon G, McLaughlin J, Maiese EM, Navaratnam P.
    Am J Rhinol Allergy. 2012 Jul;26(4):308-14.
    PMID: 22801020.
  11. Resource utilization and outcomes in patients with atrial fibrillation: a case control study.
    Boggon R, Lip GY, Gallagher AM, van Staa TP.
    Appl Health Econ Health Policy. 2012 Jul 1;10(4):249-59.
    PMID: 22540235.
  12. Colorectal cancer incidence on the General Practice Research Database.
    Charlton R, Snowball J, Bloomfield K, de Vries C.
    Pharmacoepidemiol Drug Saf. 2012 Jul;21(7):775-783.
    PMID: 22383247.
  13. Incidence of Genital Infection Among Patients with Type 2 Diabetes in the UK General Practice Research Database.
    Hirji I, Andersson SW, Guo Z, Hammar N, Gomez-Caminero A.
    J Diabetes Complications. 2012 Jul 25.
    PMID: 22840886.
  14. Resource Use and Costs Associated with Coeliac Disease before and after Diagnosis in 3,646 Cases: Results of a UK Primary Care Database Analysis.
    Violato M, Gray A, Papanicolas I, Ouellet M.
    PLoS One. 2012;7(7):e41308.
    PMID: 22815991.
  15. Drug-/radiation-induced interstitial lung disease in the United Kingdom general population: Incidence, all-cause mortality and characteristics at diagnosis.
    Amar RK, Jick SS, Rosenberg D, Maher TM, Meier CR.
    Respirology. 2012 Jul;17(5):861-868.
    PMID: 22563933.
  16. Increased risk of miscarriage and ectopic pregnancy among women with irritable bowel syndrome.
    Khashan AS, Quigley EM, McNamee R, McCarthy FP, Shanahan F, Kenny LC.
    Clin Gastroenterol Hepatol. 2012 Aug;10(8):902-9.
    PMID: 22373726.
  17. Risk of self-harm in physically ill patients in UK primary care.
    Webb RT, Kontopantelis E, Doran T, Qin P, Creed F, Kapur N.
    J Psychosom Res. 2012 Aug;73(2):92-7.
    PMID: 22789410.
  18. Risk of fracture after bariatric surgery in the United Kingdom: population based, retrospective cohort study.
    Lalmohamed A, de Vries F, Bazelier MT, Cooper A, van Staa TP, Cooper C, Harvey NC.
    BMJ. 2012 Aug 3;345:e5085.
    PMID: 22867649.
  19. The natural history of community-acquired pneumonia in COPD patients: A population database analysis.
    Müllerova H, Chigbo C, Hagan GW, Woodhead MA, Miravitlles M, Davis KJ, Wedzicha JA.
    Respir Med. 2012 Aug;106(8):1124-33.
    PMID: 22621820.
  20. The Freetext Matching Algorithm: a computer program to extract diagnoses and causes of death from unstructured text in electronic health records.
    Shah AD, Martinez C, Hemingway H
    BMC Med Inform Decis Mak. 2012 Aug 7;12(1):88.
    PMID: 22870911.
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  1. Association of systolic and diastolic blood pressure and all cause mortality in people with newly diagnosed type 2 diabetes: retrospective cohort study.
    Vamos EP, Harris M, Millett C, Pape UJ, Khunti K, Curcin V, Molokhia M, Majeed A.
    BMJ. 2012 Aug 30;345:e5567.
    PMID: 22936794
  2. A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis.
    Bazelier MT, van Staa TP, Uitdehaag BM, Cooper C, Leufkens HG, Vestergaard P, Bentzen J, de Vries F.
    Neurology. 2012 Aug 28;79(9):922-8.
    PMID: 22895583
  3. Recorded quality of primary care for patients with diabetes in England before and after the introduction of a financial incentive scheme: a longitudinal observational study.
    Kontopantelis E, Reeves D, Valderas JM, Campbell S, Doran T.
    BMJ Qual Saf. 2012 Aug 22. [Epub ahead of print]
    PMID: 22918988.
  4. Epilepsy, suicidality, and psychiatric disorders: a bidirectional association.
    Hesdorffer DC, Ishihara L, Mynepalli L, Webb DJ, Weil J, Hauser WA.
    Ann Neurol. 2012 Aug;72(2):184-91.
    PMID: 22887468.
  5. Long-term use of Angiotensin receptor blockers and the risk of cancer.
    Azoulay L, Assimes TL, Yin H, Bartels DB, Schiffrin EL, Suissa S.
    PLoS One. 2012;7(12):e50893.
    PMID: 23251399
  6. Bisphosphonates and risk of upper gastrointestinal cancer--a case control study using the General Practice Research Database (GPRD).
    Wright E, Schofield PT, Seed P, Molokhia M.
    PLoS One. 2012;7(10):e47616.
    PMID: 23112825
  7. Pramipexole use and the risk of pneumonia.
    Ernst P, Renoux C, Dell'aniello S, Suissa S.
    BMC Neurol. 2012 Sep 29;12:113.
    PMID: 23020246
  8. Smoking cessation interventions following acute coronary syndrome: a missed opportunity?
    Boggon R, Timmis A, Hemingway H, Raju S, Mondello Malvestiti F, Van Staa TP.
    Eur J Prev Cardiol. 2012 Sep 5. [Epub ahead of print]
    PMID: 22952289.
  9. Clinical features of bladder cancer in primary care.
    Shephard EA, Stapley S, Neal RD, Rose P, Walter FM, Hamilton WT.
    Br J Gen Pract. 2012 Sep;62(602):e598-604.
    PMID: 22947580
  10. Local estrogen therapy and risk of breast cancer recurrence among hormone-treated patients: a nested case-control study.
    Le Ray I, Dell'Aniello S, Bonnetain F, Azoulay L, Suissa S.
    Breast Cancer Res Treat. 2012 Sep;135(2):603-9.
    PMID: 22903687.
  11. Aspirin and other non-steroidal anti-inflammatory drug use and colorectal cancer survival: a cohort study.
    Walker AJ, Grainge MJ, Card TR.
    Br J Cancer. 2012 Oct 23;107(9):1602-7.
    PMID: 23011483
  12. The patterns of anticoagulation control and the risk of stroke, bleeding and mortality in patients with non-valvular atrial fibrillation.
    van den Ham HA, Klungel OH, Leufkens HG, van Staa TP.
    J Thromb Haemost. 2012 Oct 22. [Epub ahead of print]
    PMID: 23088617.
  13. Associations of Angiotensin Targeting Antihypertensive Drugs with Mortality and Hospitalization in Primary Care Patients with Dementia.
    Kehoe PG, Davies NM, Martin RM, Ben-Shlomo Y.
    J Alzheimers Dis. 2012 Oct 17. [Epub ahead of print]
    PMID: 23076074
  14. Comparing measures of multimorbidity to predict outcomes in primary care: a cross sectional study.
    Brilleman SL, Salisbury C.
    Fam Pract. 2012 Oct 8. [Epub ahead of print]
    PMID: 23045354.
  15. Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial.
    Dregan A, van Staa T, McDermott L, McCann G, Ashworth M, Charlton J, Wolfe C, Rudd A, Yardley L, Gulliford MC.
    Trials. 2012 Oct 3;13(1):181. [Epub ahead of print]
    PMID: 23034059.
  16. Post-marketing assessment of neuropsychiatric adverse events in influenza patients treated with oseltamivir: an updated review.
    Toovey S, Prinssen EP, Rayner CR, Thakrar BT, Dutkowski R, Koerner A, Chu T, Sirzen-Zelenskaya A, Britschgi M, Bansod S, Donner B.
    Adv Ther. 2012 Oct;29(10):826-48.
    PMID: 23054689.
  17. Defining upper gastrointestinal bleeding from linked primary and secondary care data and the effect on occurrence and 28 day mortality.
    Crooks CJ, Card TR, West J.
    BMC Health Serv Res. 2012 Nov 13;12(1):392.
    PMID: 23148590.
  18. Incidence of venous thromboembolism in patients with cancer - A cohort study using linked United Kingdom databases.
    Walker AJ, Card TR, West J, Crooks C, Grainge MJ.
    Eur J Cancer. 2012 Nov 9. [Epub ahead of print]
    PMID: 23146958.
  19. Regional and temporal variation in the treatment of rheumatoid arthritis across the UK: a descriptive register-based cohort study.
    Edwards CJ, Campbell J, van Staa T, Arden NK.
    BMJ Open. 2012 Nov 8;2(6).
    PMID: 23144258.
  20. Initial metformin or sulphonylurea exposure and cancer occurrence among patients with type 2 diabetes mellitus.
    Qiu H, Rhoads GG, Berlin JA, Marcella SW, Demissie K.
    Diabetes Obes Metab. 2012 Nov 8. [Epub ahead of print]
    PMID: 23137378.
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  1. Fracture risk with use of liver enzyme inducing antiepileptic drugs in people with active epilepsy: Cohort study using the General Practice Research Database.
    Nicholas JM, Ridsdale L, Richardson MP, Grieve AP, Gulliford MC.
    Seizure. 2012 Nov 2. [Epub ahead of print]
    PMID: 23127777.
  2. Associations of type 2 diabetes and diabetes treatment with breast cancer risk and mortality: a population-based cohort study among British women.
    Redaniel MT, Jeffreys M, May MT, Ben-Shlomo Y, Martin RM.
    Cancer Causes Control. 2012 Nov;23(11):1785-95.
    PMID: 22971998.
  3. Antidepressant switching patterns in the treatment of major depressive disorder: a General Practice Research Database (GPRD) Study.
    Saragoussi D, Chollet J, Bineau S, Chalem Y, Milea D.
    Int J Clin Pract. 2012 Nov;66(11):1079-87.
    PMID: 23067031.
  4. Incidence of urinary tract infection among patients with type 2 diabetes in the UK General Practice Research Database (GPRD).
    Hirji I, Guo Z, Andersson SW, Hammar N, Gomez-Caminero A.
    J Diabetes Complications. 2012 Nov;26(6):513-6.
    PMID: 22889712.
  5. Metformin does not alter the risk of lung cancer: a case-control analysis.
    Bodmer M, Becker C, Jick SS, Meier CR.
    Lung Cancer. 2012 Nov;78(2):133-7.
    PMID: 22959242.
  6. Proton pump inhibitors and traditional nonsteroidal anti-inflammatory drugs and the risk of acute interstitial nephritis and acute kidney injury.
    Leonard CE, Freeman CP, Newcomb CW, Reese PP, Herlim M, Bilker WB, Hennessy S, Strom BL.
    Pharmacoepidemiol Drug Saf. 2012 Nov;21(11):1155-72.
    PMID: 22887960.
  7. Comparison of prescription drug costs in the United States and the United kingdom, part 3: methylphenidate.
    Jick H, Wilson A, Wiggins P, Chamberlin DP.
    Pharmacotherapy. 2012 Nov;32(11):970-3.
    PMID: 23108719.
  8. Representativeness of the dabigatran, apixaban and rivaroxaban clinical trial populations to real-world atrial fibrillation patients in the United Kingdom: a cross-sectional analysis using the General Practice Research Database.
    Lee S, Monz BU, Clemens A, Brueckmann M, Lip GY.
    BMJ Open. 2012 Dec 14;2(6).
    PMID: 23242482.
  9. Cancer recording and mortality in the General Practice Research Database and linked cancer registries.
    Boggon R, van Staa TP, Chapman M, Gallagher AM, Hammad TA, Richards MA.
    Pharmacoepidemiol Drug Saf. 2012 Dec 13.[Epub ahead of print]
    PMID: 23239282.
  10. Omega-3 Fatty Acids and Mortality Outcome in Patients With and Without Type 2 Diabetes After Myocardial Infarction: A Retrospective, Matched-Cohort Study.
    Poole CD, Halcox JP, Jenkins-Jones S, Carr ES, Schifflers MG, Ray KK, Currie CJ
    Clin Ther. 2012 Dec 12. [Epub ahead of print]
    PMID: 23246017.
  11. Opioid prescribing for cancer pain during the last 3 months of life: associated factors and 9-year trends in a nationwide United kingdom cohort study.
    Higginson IJ, Gao W.
    J Clin Oncol. 2012 Dec 10;30(35):4373-9.
    PMID: 23109701.
  12. Validation of Suicide and Self-harm records in the Clinical Practice Research Datalink.
    Thomas KH, Davies N, Metcalfe C, Windmeijer F, Martin RM, Gunnell D.
    Br J Clin Pharmacol. 2012 Dec 6. [Epub ahead of print]
    PMID: 23216533.
  13. Seizures in patients with Alzheimer's disease or vascular dementia: A population-based nested case-control analysis.
    Imfeld P, Bodmer M, Schuerch M, Jick SS, Meier CR
    Epilepsia. 2012 Dec 6.[Epub ahead of print]
    PMID: 23215680.
  14. Data Resource Profile: Cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER). Denaxas SC, George J, Herrett E, Shah AD, Kalra D, Hingorani AD, Kivimaki M,
    Timmis AD, Smeeth L, Hemingway H.
    Int J Epidemiol. 2012 Dec 5. [Epub ahead of print]
    PMID: 23220717.
  15. Patient-related risk factors for fracture-healing complications in the United Kingdom General Practice Research Database.
    Hernandez RK, Do TP, Critchlow CW, Dent RE, Jick SS.
    Acta Orthop. 2012 Dec;83(6):653-60.
    PMID: 23140093.
  16. Prescription of antiviral therapy after herpes zoster in general practice: who receives therapy?
    Forbes HJ, Thomas SL, Smeeth L, Langan SM.
    Br J Gen Pract.2012 Dec;62(605):808-14
    PMID: 23211260
  17. Survival of glioma and colorectal cancer patients using tricyclic antidepressants post-diagnosis.
    Walker AJ, Grainge M, Bates TE, Card TR.
    Cancer Causes Control. 2012 Dec;23(12):1959-64.
    PMID: 23065071.
  18. Epidemiology of castration resistant prostate cancer: A longitudinal analysis using a UK primary care database.
    Hirst CJ, Cabrera C, Kirby M.
    Cancer Epidemiol. 2012 Dec;36(6):e349-53.
    PMID: 22910034
  19. Comorbidities in Perthes' disease: A case control study using the General Practice Research Database.
    Perry DC, Bruce CE, Pope D, Dangerfield P, Platt MJ, Hall AJ.
    J Bone Joint Surg Br. 2012 Dec;94(12):1684-9.
    PMID: 23188912.
  20. What next after metformin? A retrospective evaluation of the outcome of second-line, glucose-lowering therapies in people with type 2 diabetes.
    Morgan CL, Poole CD, Evans M, Barnett AH, Jenkins-Jones S, Currie CJ.
    J Clin Endocrinol Metab. 2012 Dec;97(12):4605-12.
    PMID: 23076348.
  21. Influenza Infection and Risk of Acute Myocardial Infarction in England and Wales: A CALIBER Self-Controlled Case Series Study.
    Warren-Gash C, Hayward AC, Hemingway H, Denaxas S, Thomas SL, Timmis AD, Whitaker H, Smeeth L.
    J Infect Dis. 2012 Dec;206(11):1652-9.
    PMID: 23048170
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Research Papers - 2011

  1. Tricyclic antidepressants and the incidence of certain cancers: a study using the GPRD.
    Walker AJ, Card T, Bates TE, Muir K.
    Br J Cancer. 2011 Jan 4;104(1):193-7. Epub 2010 Nov 16.
    PMID: 21081933
  2. Antihypertensive treatment after first stroke in primary care: results from the General Practitioner Research Database.
    Toschke AM, Gulliford MC, Wolfe CD, Rudd AG, Heuschmann PU.
    J Hypertens. 2011 Jan; 29(1):154-60.
    PMID: 20842045
  3. The use of antidepressants and the risk of haemorrhagic stroke: a nested case control study.
    Douglas I, Smeeth L, Irvine D.
    Br J Clin Pharmacol. 2011 Jan;71(1):116-20.
    PMID: 21143507
  4. Changes in hip fracture rate before and after total knee replacement due to osteoarthritis: a population-based cohort study.
    Prieto-Alhambra D, Javaid MK, Maskell J, Judge A, Nevitt M, Cooper C, Arden NK.
    Ann Rheum Dis. 2011 Jan;70(1):134-8. Epub 2010 Oct 26. PMID: 20980287
  5. The effect of hip and knee arthroplasty on oral anti-inflammatory use and the relationship to body mass index: results from the UK general practice research database.
    Bolland BJ, Culliford DJ, Maskell J, Latham JM, Dunlop DG, Arden NK.
    Osteoarthritis Cartilage. 2011 Jan;19(1):29-36. Epub 2010 Oct 27.
    PMID: 21034838
  6. Concurrent drug use and the risk of perforated colonic diverticular disease: a population-based case-control study.
    Humes DJ, Fleming KM, Spiller RC, West J.
    Gut. 2011 Feb;60(2):219-24. Epub 2010 Oct 12.
    PMID: 20940283
  7. Epidemiology and impact of multimorbidity in primary care: a retrospective cohort study
    Salisbury C, Johnson L, Purdy S, Valderas JM, Montgomery AA.
    Br J Gen Pract. 2011 Jan;61(582):e12-21.
    PMID: 21401985
  8. Utility of electronic patient records in primary care for stroke secondary prevention trials.
    Dregan A, Toschke MA, Wolfe CD, Rudd A, Ashworth M, Gulliford MC; eCRT Research team.
    BMC Public Health. 2011 Feb 7;11:86.
    PMID: 21299872
  9. Comparing the General Practice Research Database and the UK Epilepsy and Pregnancy Register as tools for postmarketing teratogen surveillance: anticonvulsants and the risk of major congenital malformations.
    Charlton RA, Weil JG, Cunnington MC, Ray S, de Vries CS.
    Drug Saf. 2011 Feb 1;34(2):157-71.
    PMID: 21247222
  10. Treatment persistence and cost-effectiveness of latanoprost/latanoprost-timolol, bimatoprost/bimatoprost-timolol, and travoprost/travoprost-timolol in glaucoma: an analysis based on the United Kingdom general practitioner research database.
    Lafuma A, Salmon JF, Robert J, Berdeaux G.
    Clin Ophthalmol. 2011;5:361-7. Epub 2011 Mar 14.
    PMID: 21468347
  11. Parkinson's disease or Parkinson symptoms following seasonal influenza.
    Toovey S, Jick SS, Meier CR.
    Influenza Other Respi Viruses. 2011 Mar 21. [Epub ahead of print]
    PMID: 21668692.
  12. Primary care consultation behaviours of long-term, adult survivors of cancer in the UK.
    Khan NF, Watson E, Rose PW.
    Br J Gen Pract. 2011 Mar;61(584):197-9.
    PMID: 21375904.
  13. Estimation of the rate of pelvic inflammatory disease diagnoses: trends in England, 2000-2008.
    French CE, Hughes G, Nicholson A, Yung M, Ross JD, Williams T, Soldan K.
    Sex Transm Dis. 2011 Mar;38(3):158-62.
    PMID: 21311319.
  14. The relationship between neurological disease and bullous pemphigoid: a population-based case-control study.
    Langan SM, Groves RW, West J.
    J Invest Dermatol. 2011 Mar;131(3):631-6. Epub 2010 Nov 18.
    PMID: 21085189.
  15. Effectiveness of inhaler types for real-world asthma management: retrospective observational study using the GPRD.
    Price D, Haughney J, Sims E, Ali M, von Ziegenweidt J, Hillyer EV, Lee AJ, Chisholm A, Barnes N. J Asthma
    Allergy. 2011; 4:37-47. Epub 2011 Apr 28.
    PMID: 21698214.
  16. All-cause mortality in people with cirrhosis compared with the general population: a population-based cohort study.
    Fleming KM, Aithal GP, Card TR, West J.
    Liver Int. 2011 Apr 6. [Epub ahead of print]
    PMID: 21745279.
  17. Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: nested case-control study based on UK General Practice Research Database.
    Parkin L, Sharples K, Hernandez RK, Jick SS.
    BMJ. 2011 Apr 21;342:d2139.
    PMID: 21511804.
  18. Higher Incidence of Common Diagnoses in Patients with Low Back Pain in Primary Care.
    Bartholomeeusen S, Van Zundert J, Truyers C, Buntinx F, Paulus D.
    Pain Pract. 2011 Apr 20. [Epub ahead of print]
    PMID: 21507198.
  19. Weight and glycaemic control in type 2 diabetes: what is the outcome of insulin initiation?
    Watson L, Wilson BP, Alsop J, Kumar S.
    Diabetes Obes Metab. 2011 Apr 11. [Epub ahead of print]
    PMID: 21481128.
  20. The use of atypical antipsychotics and the risk of breast cancer.
    Azoulay L, Yin H, Renoux C, Suissa S.
    Breast Cancer Res Treat. 2011 Apr 9. [Epub ahead of print]
    PMID: 21479550.
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  1. NSAID use and risk of Parkinson disease: a population-based case-control study.
    Becker C, Jick SS, Meier CR.
    Eur J Neurol. 2011 Apr 4. [Epub ahead of print]
    PMID: 21457177.
  2. Fracture risk before and after total hip replacement in patients with osteoarthritis: potential benefits of bisphosphonate use.
    Prieto-Alhambra D, Javaid MK, Judge A, Maskell J, Kiran A, de Vries F, Cooper C, Arden NK.
    Arthritis Rheum. 2011 Apr;63(4):992-1001.
    PMID: 21452321.
  3. Risk factors for intestinal ischaemia among patients registered in a UK primary care database: a nested case-control study.
    Huerta C, Rivero E, Montoro MA, García-Rodriguez LA.
    Aliment Pharmacol Ther. 2011 Apr;33(8):969-78. Epub 2011 Mar 1.
    PMID: 21366637.
  4. Efficiency of glaucoma drug regulation in 5 European countries: a 1995-2006 longitudinal prescription analysis.
    De Natale R, Le Pen C, Berdeaux G.
    J Glaucoma. 2011 Apr-May;20(4):234-9.
    PMID: 21682002.
  5. Epilepsy mortality and risk factors for death in epilepsy: a population-based study.
    Ridsdale L, Charlton J, Ashworth M, Richardson MP, Gulliford MC.
    Br J Gen Pract. 2011 May;61(586):271-8.
    PMID: 21619751.
  6. Long-term effects of insulin glargine on the risk of breast cancer.
    Suissa S, Azoulay L, Dell'aniello S, Evans M, Vora J, Pollak M.
    Diabetologia. 2011 May 26.
    PMID: 21614572.
  7. Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study).
    Gulliford MC, van Staa T, McDermott L, Dregan A, McCann G, Ashworth M, Charlton J, Grieve AP, Little P, Moore MV, Yardley L; electronic Cluster Randomised Trial Research Team eCRT Research Team.
    Trials. 2011 May 10;12:115.
    PMID: 21569237.
  8. Prescription patterns of analgesics in the last 3 months of life: a retrospective analysis of 10202 lung cancer patients.
    Gao W, Gulliford M, Higginson IJ.
    Br J Cancer. 2011 May 24;104(11):1704-10. Epub 2011 May 3.
    PMID: 21540860.
  9. Diabetes mellitus and the risk of cholecystectomy.
    Bodmer M, Brauchli YB, Jick SS, Meier CR.
    Dig Liver Dis. 2011 May 24. [Epub ahead of print]
    PMID: 21616732.
  10. Body mass index and the incidence of influenza-associated pneumonia in a UK primary care cohort.
    Blumentals WA, Nevitt A, Peng MM, Toovey S.
    Influenza Other Respi Viruses. 2011 May 19. [Epub ahead of print]
    PMID: 21668664.
  11. Threshold haemoglobin levels and the prognosis of stable coronary disease: two new cohorts and a systematic review and meta-analysis.
    Shah AD, Nicholas O, Timmis AD, Feder G, Abrams KR, Chen R, Hingorani AD, Hemingway H.
    PLoS Med. 2011 May;8(5):e1000439. Epub 2011 May 31.
    PMID: 21655315.
  12. The risk of fracture in patients with multiple sclerosis: the UK general practice research database.
    Bazelier MT, van Staa TP, Uitdehaag BM, Cooper C, Leufkens HG, Vestergaard P, Bentzen J, de Vries F
    J Bone Miner Res. 2011 May 6. [Epub ahead of print]
    PMID: 21557309.
  13. Role of acute diverticulitis in the development of complicated colonic diverticular disease and 1-year mortality after diagnosis in the UK: population-based cohort study.
    Humes DJ, West J.
    Gut. 2011 May 6. [Epub ahead of print]
    PMID: 21551188.
  14. Use of tamoxifen and aromatase inhibitors in a large population-based cohort of women with breast cancer.
    Huiart L, Dell'Aniello S, Suissa S.
    Br J Cancer. 2011 May 10;104(10):1558-63. Epub 2011 Apr 26.
    PMID: 21522148.
  15. Mortality rates and causes of death in children with epilepsy prescribed antiepileptic drugs: a retrospective cohort study using the UK General Practice Research Database.
    Ackers R, Besag FM, Hughes E, Squier W, Murray ML, Wong IC.
    Drug Saf. 2011 May 1;34(5):403-13.
    PMID: 21513363.
  16. Frequency and risk factors of gout flares in a large population-based cohort of incident gout.
    Rothenbacher D, Primatesta P, Ferreira A, Cea-Soriano L, Rodríguez LA.
    Rheumatology (Oxford). 2011 May;50(5):973-81. Epub 2011 Jan 12.
    PMID: 21228059.
  17. Estimating the effect of nasal steroid treatment on repeat polypectomies: survival time analysis using the General Practice Research Database.
    Punekar YS, Ahmad A, Saleh HA.
    Rhinology. 2011 Jun;49(2):190-4.
    PMID: 21743875.
  18. Academic impact of a public electronic health database: bibliometric analysis of studies using the general practice research database.
    Chen YC, Wu JC, Haschler I, Majeed A, Chen TJ, Wetter T.
    PLoS One. 2011;6(6):e21404. Epub 2011 Jun 22.
    PMID: 21731733.
  19. Risk of cerebrovascular accident associated with use of antipsychotics: population-based case-control study.
    Laredo L, Vargas E, Blasco AJ, Aguilar MD, Moreno A, Portolés A.
    J Am Geriatr Soc. 2011 Jul;59(7):1182-7. Epub 2011 Jun 30.
    PMID: 21718267.
  20. Menopausal hormone therapy and risk of gastrointestinal cancer: Nested case-control study within a prospective cohort, and meta-analysis.
    Green J, Czanner G, Reeves G, Watson J, Wise L, Roddam A, Beral V.
    Int J Cancer. 2011 Jun 13. doi: 10.1002/ijc.26236. [Epub ahead of print]
    PMID: 21671473.
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  1. Prescription patterns in asthma patients initiating salmeterol in UK general practice: a retrospective cohort study using the General Practice Research Database (GPRD).
    DiSantostefano RL, Davis KJ.
    Drug Saf. 2011 Jun 1;34(6):511-20.
    PMID: 21585223.
  2. Associations of Anti-Hypertensive Treatments with Alzheimer's Disease, Vascular Dementia, and Other Dementias.
    Davies NM, Kehoe PG, Ben-Shlomo Y, Martin RM.
    J Alzheimers Dis. 2011 Jun 27. [Epub ahead of print]
    PMID: 21709373.
  3. The Relationship between Asthma and Depression in Primary Care Patients: A Historical Cohort and Nested Case Control Study.
    Walters P, Schofield P, Howard L, Ashworth M, Tylee A.
    PLoS One. 2011;6(6):e20750. Epub 2011 Jun 15.
    PMID: 21698276.
  4. Impact of rosiglitazone therapy on the lipid profile, glycemic control, and medication costs among type 2 diabetes patients.
    Suh DC, Lee DH, McGuire M, Kim CM.
    Curr Med Res Opin. 2011 Aug;27(8):1623-33. Epub 2011 Jun 22.
    PMID: 21696266.
  5. Suboptimal gastroprotective coverage of NSAID use and the risk of upper gastrointestinal bleeding and ulcers: an observational study using three European databases.
    van Soest EM, Valkhoff VE, Mazzaglia G, Schade R, Molokhia M, Goldstein JL, Hernández-Díaz S, Trifirò G, Dieleman JP, Kuipers EJ, Sturkenboom MC.
    Gut. 2011 Jun 2. [Epub ahead of print]
    PMID: 21636644.
  6. Gynaecological symptoms reported to primary care by women aged 15-29 years: a historical cohort study using electronic medical records, examining the potential for earlier diagnosis of cervical cancer.
    Stapley S, Hamilton W.
    Fam Pract. 2011 Jun 1. [Epub ahead of print]
    PMID: 21632969.
  7. Bisphosphonates and esophageal cancer-a pathway through the confusion.
    Dixon WG, Solomon DH.
    Nat Rev Rheumatol. 2011 Jun;7(6):369-72. Epub 2011 May 3.
    PMID: 21537362.
  8. Use of antihypertensive medications and mortality of patients with autosomal dominant polycystic kidney disease: a population-based study.
    Patch C, Charlton J, Roderick PJ, Gulliford MC.
    Am J Kidney Dis. 2011 Jun;57(6):856-62. Epub 2011 Apr 2.
    PMID: 21458899.
  9. Increased Risk of Myocardial Infarction Among Patients with Ulcerative Colitis or Crohn's Disease.
    Osterman MT, Yang YX, Brensinger C, Forde KA, Lichtenstein GR, Lewis JD. No
    Clin Gastroenterol Hepatol. 2011 Jul 9. [Epub ahead of print]
    PMID: 21749853.
  10. Evidence-based (S3) guideline on topical corticosteroids in pregnancy.
    Chi CC, Kirtschig G, Aberer W, Gabbud JP, Lipozenčić J, Kárpáti S, Haustein UF, Zuberbier T, Wojnarowska F. Br J
    Dermatol. 2011 Jul 5. [Epub ahead of print]
    PMID: 21729030.
  11. Validity of diagnoses in the General Practice Research Database.
    Herrett EL, Thomas SL, Smeeth L.
    Br J Gen Pract. 2011 Jul;61(588):438-9.
    PMID: 21722461.
  12. Statin use and risk of first-time psoriasis diagnosis.
    Brauchli YB, Jick SS, Meier CR.
    J Am Acad Dermatol. 2011 Jul;65(1):77-83. Epub 2011 May 6.
    PMID: 21529997.
  13. Trends in Type 1 diabetes incidence in the UK in 0- to 14-year-olds and in 15- to 34-year-olds, 1991-2008.
    Imkampe AK, Gulliford MC.
    Diabet Med. 2011 Jul;28(7):811-4.
    PMID: 21395679.
  14. Predictors of incident atrial fibrillation and influence of medications: a retrospective case-control study.
    Hodgkinson JA, Taylor CJ, Hobbs FD.
    Br J Gen Pract. 2011 Jun;61(587):e353-61.
    PMID: 21801515
  15. Comprehensive comparison of drug prescribing in the United States and United Kingdom.
    Parkin L, Hagberg KW, Jick H.
    Pharmacotherapy. 2011 Jul;31(7):623-9.
    PMID: 21923448.
  16. Use of metformin and the risk of ovarian cancer: A case-control analysis.
    Bodmer M, Becker C, Meier C, Jick SS, Meier CR.
    Gynecol Oncol. 2011 Jul 28. [Epub ahead of print]
    PMID: 21802715.
  17. Thiazolidinediones and the risk of incident congestive heart failure among patients with type 2 diabetes mellitus.
    Filion KB, Joseph L, Boivin JF, Suissa S, Brophy JM.
    Pharmacoepidemiol Drug Saf. 2011 Aug;20(8):785-96. doi: 10.1002/pds.2165. Epub 2011 Jun 13.
    PMID: 21671441
  18. Attributable risk estimate of severe psoriasis on major cardiovascular events.
    Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, Shin DB, Troxel AB, Gelfand JM.
    Am J Med. 2011 Aug;124(8):775.e1-6.
    PMID: 21787906
  19. Thiazolidinediones and the risk of incident congestive heart failure among patients with type 2 diabetes mellitus.
    Filion KB, Joseph L, Boivin JF, Suissa S, Brophy JM.
    Pharmacoepidemiol Drug Saf. 2011 Aug;20(8):785-96. doi: 10.1002/pds.2165. Epub 2011 Jun 13.
    PMID: 21671441
  20. Antibacterial Drugs and the Risk of Community-Associated Methicillin-Resistant Staphylococcus aureus in Children.
    Schneider-Lindner V, Quach C, Hanley JA, Suissa S.
    Arch Pediatr Adolesc Med. 2011 Aug 1.
    PMID: 21810624
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  1. Association of practice size and pay-for-performance incentives with the quality of diabetes management in primary care.
    Vamos EP, Pape UJ, Bottle A, Hamilton FL, Curcin V, Ng A, Molokhia M, Car J, Majeed A, Millett C.
    CMAJ. 2011 Sep 6;183(12):E809-16. Epub 2011 Aug 2.
    PMID: 21810950
  2. Genital warts and cost of care in England.
    Desai S, Wetten S, Woodhall SC, Peters L, Hughes G, Soldan K.
    Sex Transm Infect. 2011 Oct;87(6):464-8. Epub 2011 Aug 3.
    PMID: 21813567
  3. An increased risk of urinary tract infection precedes development of primary biliary cirrhosis.
    Varyani FK, West J, Card TR.
    BMC Gastroenterol. 2011 Aug 26;11:95.
    PMID: 21871059
  4. Androgen-Deprivation Therapy and the Risk of Stroke in Patients With Prostate Cancer.
    Azoulay L, Yin H, Benayoun S, Renoux C, Boivin JF, Suissa S.
    Eur Urol. 2011 Aug 27. [Epub ahead of print]
    PMID: 21908097
  5. Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction--a hospital registry-primary care linked cohort (MINAP-GPRD).
    Boggon R, van Staa TP, Timmis A, Hemingway H, Ray KK, Begg A, Emmas C, Fox KA.
    Eur Heart J. 2011 Oct;32(19):2376-86. Epub 2011 Aug 29.
    PMID: 21875855
  6. Angiotensin converting enzyme inhibitors and hepatocellular carcinoma incidence in the General Practice Research Database.
    Walker AJ, West J, Grainge MJ, Card TR.
    Cancer Causes Control. 2011 Sep 11. [Epub ahead of print]
    PMID: 21909951
  7. Mortality in children and adolescents prescribed antipsychotic medication: a retrospective cohort study using the UK general practice research database.
    Rani FA, Byrne P, Cranswick N, Murray ML, Wong IC.
    Drug Saf. 2011 Sep 1;34(9):773-81. doi: 10.2165/11591120-000000000-00000.
    PMID: 21830839
  8. Risks of stroke and mortality associated with suboptimal anticoagulation in atrial fibrillation patients.
    Gallagher AM, Setakis E, Plumb JM, Clemens A, van Staa TP.
    Thromb Haemost. 2011 Sep 8;106(5). [Epub ahead of print]
    PMID: 21901239
  9. Identification of esophageal cancer in the General Practice Research Database.
    Walker AM.
    Pharmacoepidemiol Drug Saf. 2011 Sep 16. doi:10.1002/pds.2249. [Epub ahead of print]
    PMID: 21928362.
  10. An evaluation of Birmingham Own Health® telephone care management service among patients with poorly controlled diabetes. a retrospective comparison with the General Practice Research Database.
    Jordan RE, Lancashire RJ, Adab P.
    BMC Public Health. 2011 Sep 19;11:707.
    PMID: 21929804
  11. Long-term use of fluticasone propionate/salmeterol fixed-dose combination and incidence of cataracts and glaucoma among chronic obstructive pulmonary disease patients in the UK General Practice Research Database
    Miller DP, Watkins SE, Sampson T, Davis KJ.
    Int J Chron Obstruct Pulmon Dis. 2011;6:467-76. Epub 2011 Sep 16.
    PMID: 22003292
  12. Persistence with osteoporosis medications among postmenopausal women in the UK General Practice Research Database.
    Li L, Roddam A, Gitlin M, Taylor A, Shepherd S, Shearer A, Jick S.
    Menopause. 2011 Sep 15. [Epub ahead of print]
    PMID: 21926926
  13. Use of statins is associated with an increased risk of rheumatoid arthritis.
    de Jong HJ, Klungel OH, van Dijk L, Vandebriel RJ, Leufkens HG, van der Laan J, Tervaert JW, van Loveren H.
    Ann Rheum Dis. 2011 Oct 6. [Epub ahead of print]
    PMID: 21979000.
  14. Seasonality of medical contacts in school-aged children with asthma: association with school holidays.
    Julious SA, Campbell MJ, Bianchi SM, Murray-Thomas T.
    Public Health. 2011 Nov;125(11):769-76. Epub 2011 Oct 28.
    PMID: 22036686.
  15. Risk of convulsions in children after monovalent H1N1 (2009) and trivalent influenza vaccines: a database study.
    Stowe J, Andrews N, Bryan P, Seabroke S, Miller E.
    Vaccine. 2011 Nov 28;29(51):9467-72. Epub 2011 Oct 20.
    PMID: 22019757.
  16. Risk of cataract and glaucoma in patients with multiple sclerosis.
    Bazelier MT, Mueller-Schotte S, Leufkens HG, Uitdehaag BM, van Staa T, de Vries F.
    Mult Scler. 2011 Oct 24. [Epub ahead of print]
    PMID: 22025330.
  17. Risk of acute renal failure in patients with Type diabetes mellitus.
    Girman CJ, Kou TD, Brodovicz K, Alexander CM, O'Neill EA, Engel S, Williams-Herman DE, Katz L.
    Diabet Med. 2011 Oct 20. doi:10.1111/j.1464-5491.2011.03498.x. [Epub ahead of print]
    PMID: 22017349.
  18. Glucose-lowering agents and the patterns of risk for cancer: a study with the General Practice Research Database and secondary care data.
    van Staa TP, Patel D, Gallagher AM, de Bruin ML.
    Diabetologia. 2012 Mar;55(3):654-65. Epub 2011 Nov 30.
    PMID: 22127412.
  19. The LUCK study: Laxative Usage in patients with GP-diagnosed Constipation in the UK, within the general population and in pregnancy. An epidemiological study using the General Practice Research Database (GPRD).
    Shafe AC, Lee S, Dalrymple JS, Whorwell PJ.
    Therap Adv Gastroenterol. 2011 Nov;4(6):343-63.
    PMID: 22043228.
  20. The London low emission zone baseline study.
    Kelly F, Armstrong B, Atkinson R, Anderson HR, Barratt B, Beevers S, Cook D, Green D, Derwent D, Mudway I, Wilkinson P; HEI Health Review Committee.
    Res Rep Health Eff Inst. 2011 Nov;(163):3-79.
    PMID: 22315924.
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  1. Cancer risk in people with epilepsy using valproate-sodium.
    Singh G, Bell GS, Driever PH, Sander JW.
    Acta Neurol Scand. 2011 Nov 12. doi:10.1111/j.1600-0404.2011.01607.x. [Epub ahead of print]
    PMID: 22077648.
  2. Long-term health outcomes in a British cohort of breast, colorectal and prostate cancer survivors: a database study.
    Khan NF, Mant D, Carpenter L, Forman D, Rose PW.
    Br J Cancer. 2011 Nov 8;105 Suppl 1:S29-37. doi: 10.1038/bjc.2011.420.
    PMID: 22048030.
  3. Androgen deprivation therapy and the risk of coronary heart disease and heart failure in patients with prostate cancer: a nested case-control study in UK primary care.
    Martín-Merino E, Johansson S, Morris T, García Rodríguez LA.
    Drug Saf. 2011 Nov 1;34(11):1061-77. doi: 10.2165/11594540-000000000-00000.
    PMID: 21981434.
  4. Factors associated with uptake of seasonal and pandemic influenza vaccine among clinical risk groups in the UK: An analysis using the General Practice Research Database.
    Sammon CJ, McGrogan A, Snowball J, de Vries CS.
    Vaccine. 2011 Nov 28. [Epub ahead of print]
    PMID: 22133511.
  5. Perthes' disease in the UK: Geographic and temporal trends in incidence reflecting deprivation inequalities in childhood.
    Perry DC, Bruce CE, Pope D, Dangerfield P, Platt MJ, Hall AJ.
    Arthritis Rheum. 2011 Dec 5. doi:10.1002/art.34316. [Epub ahead of print]
    PMID: 22143958.
  6. Prevalence of diagnosed adult immune thrombocytopenia in the United kingdom.
    Bennett D, Hodgson ME, Shukla A, Logie JW.
    Adv Ther. 2011 Dec;28(12):1096-104. Epub 2011 Dec 1.
    PMID: 22139790.
  7. Risk of cancer in patients exposed to gabapentin in two electronic medical record Systems.
    Irizarry MC, Webb DJ, Boudiaf N, Logie J, Habel LA, Udaltsova N, Friedman GD.
    Pharmacoepidemiol Drug Saf. 2012 Feb;21(2):214-25. doi:10.1002/pds.2266. Epub 2011 Dec 6.
    PMID: 22144034.
  8. Risk of Tuberculosis in Pregnancy: A National, Primary Care Based Cohort and Self-Controlled Case Series Study.
    Zenner D, Kruijshaar ME, Andrews N, Abubakar I.
    Am J Respir Crit Care Med. 2011 Dec 8. [Epub ahead of print]
    PMID: 22161161.
  9. Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study.
    Ernst P, Dell'aniello S, Mikaeloff Y, Suissa S.
    BMC Pulm Med. 2011 Dec 16;11:59.
    PMID: 22177425.
  10. Potential application of item-response theory to interpretation of medical codes in electronic patient records.
    Dregan A, Grieve A, van Staa T, Gulliford MC; the eCRT Research Team.
    BMC Med Res Methodol. 2011 Dec 16;11(1):168.
    PMID: 22176509.
  11. Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data.
    Gallagher AM, Smeeth L, Seabroke S, Leufkens HG, van Staa TP.
    PLoS One. 2011;6(12):e28157. Epub 2011 Dec 2.
    PMID: 22164237.
  12. Exposure to oral bisphosphonates and risk of cancer.
    Cardwell CR, Abnet CC, Veal P, Hughes CM, Cantwell MM, Murray LJ.
    Int J Cancer. 2011 Dec 8. doi: 10.1002/ijc.27389. [Epub ahead of print]
    PMID: 22161552.
  13. The positivity assumption and marginal structural models: the example of warfarin use and risk of bleeding.
    Platt RW, Delaney JA, Suissa S.
    Eur J Epidemiol. 2011 Dec 8. [Epub ahead of print]
    PMID: 22160333.
  14. Association between bisphosphonate use and implant survival after primary total arthroplasty of the knee or hip: population based retrospective cohort study.
    Prieto-Alhambra D, Javaid MK, Judge A, Murray D, Carr A, Cooper C, Arden NK.
    BMJ. 2011 Dec 6;343:d7222. doi: 10.1136/bmj.d7222.
    PMID: 22147909.
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Research Papers - 2010

  1. Validation and validity of diagnoses in the General Practice Research Database: a systematic review.
    Herrett E, Thomas SL, Schoonen WM, Smeeth L, Hall AJ.Br J
    Clin Pharmacol. 2010 Jan; 69(1):4-14.
    PMID: 20078607
  2. Exploring differential prescribing between anti-epileptic drugs in epilepsy patients with a history of mood disorders.
    Ishihara L, Webb DJ, Irizarry M, Weil J.
    Pharmacoepidemiol Drug Saf. 2010 Jan 14. [Epub ahead of print]
    PMID: 20077522
  3. Combination therapy with sulfonylureas and metformin and the prevention of death in type 2 diabetes: a nested case-control study.
    Azoulay L, Schneider-Lindner V, Dell'aniello S, Schiffrin A, Suissa S.
    Pharmacoepidemiol Drug Saf. 2010 Jan 5. [Epub ahead of print]
    PMID: 20052677
  4. Adaptation and validation of the Charlson Index for Read/OXMIS coded databases.
    Khan NF, Perera R, Harper S, Rose PW.
    BMC Fam Pract. 2010 Jan 5;11(1):1.[Epub ahead of print]
    PMID: 20051110
  5. Phynx: an open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases.
    Egbring M, Kullak-Ublick GA, Russmann S.
    Pharmacoepidemiol Drug Saf. 2010 Jan;19(1):38-44.
    PMID: 19777533
  6. Risk of Cancer in Inflammatory Bowel Disease Treated With Azathioprine: A UK Population-Based Case-Control Study.
    Armstrong RG, West J, Card TR.
    Am J Gastroenterol. 2010 Jan 26. [Epub ahead of print]
    PubMed PMID: 20104215
  7. Risk for incident atrial fibrillation in patients who receive antihypertensive drugs: a nested case-control study.
    Schaer BA, Schneider C, Jick SS, Conen D, Osswald S, Meier CR.
    Ann Intern Med. 2010 Jan 19;152 (2):78-84.
    PMID: 20083826
  8. Temporal trends in hip and knee replacement in the United Kingdom: 1991 to 2006.
    Culliford DJ, Maskell J, Beard DJ, Murray DW, Price AJ, Arden NK.
    J Bone Joint Surg Br. 2010 Jan;92(1):130-5.
    PMID: 20044691
  9. Association between dyslipidemia and vascular events in patients treated with statins: Report from the UK General Practice Research Database.
    Sazonov V, Beetsch J, Phatak H, Wentworth C, Evans M.
    Atherosclerosis. 2010 Jan;208(1):210-216. Epub 2009 Sep 20.
    PMID: 19766999
  10. Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: a prospective study.
    Alonso A, Logroscino G, Jick SS, Hernán MA.
    BMC Neurol. 2010 Jan 14;10:6.
    PMID: 20074360
  11. The identification of pregnancies within the general practice research database.
    Devine S, West S, Andrews E, Tennis P, Hammad TA, Eaton S, Thorp J, Olshan A.
    Pharmacoepidemiol Drug Saf. 2010 Jan;19(1):45-50.
    PMID: 19823973
  12. Survival as a function of HbA(1c) in people with type 2 diabetes: a retrospective cohort study.
    Currie CJ, Peters JR, Tynan A, Evans M, Heine RJ, Bracco OL, Zagar T, Poole CD.
    Lancet. 2010 Feb 6;375(9713):481-9.
    PMID: 20110121
  13. Use of venlafaxine compared with other antidepressants and the risk of sudden cardiac death or near death: a nested case-control study.
    Martinez C, Assimes TL, Mines D, Dell'aniello S, Suissa S.
    BMJ. 2010 Feb 5;340:c249.
    PMID: 20139216
  14. Thromboembolic events among adult patients with primary immune thrombocytopenia (ITP) in the United Kingdom General Practice Research Database.
    Sarpatwari A, Bennett D, Logie JW, Shukla A, Beach KJ, Newland A, Sanderson S, Provan D.
    Haematologica. 2010 Feb 9.
    PMID: 20145266
  15. Prospective drug safety monitoring using the UK primary-care General Practice Research Database: theoretical framework, feasibility analysis and extrapolation to future scenarios.
    Johansson S, Wallander MA, de Abajo FJ, García Rodríguez LA.
    Drug Saf. 2010 Mar 1;33(3):223-32.
    PMID: 20158286
  16. Are GPs under-investigating older patients presenting with symptoms of ovarian cancer? Observational study using General Practice Research Database.
    Tate AR, Nicholson A, Cassell JA.
    Br J Cancer. 2010 Mar 16;102(6):947-51.
    PMID: 20197770
  17. Mortality and cancer in patients with new musculoskeletal episodes: a cohort study.
    Jordan KP, Croft P.
    Br J Gen Pract. 2010 Mar;60(572):e105-11.
    PMID: 20202352
  18. Validity of diagnostic coding within the General Practice Research Database: a systematic review.
    Khan NF, Harrison SE, Rose PW. Br J Gen Pract. 2010 Mar; 60(572):e128-36. Review.
    PMID: 20202356
  19. Hormone replacement therapy and the risk of venous thromboembolism: population-based study.
    Renoux C, Dell'aniello S, Suissa S.
    J Thromb Haemost. 2010 Mar 4.
    PMID: 20230416
  20. Determining patient characteristics for decision analysis support systems using anonymized electronic patient records.
    Frisher M, Short D, Bashford J.
    Health Informatics J. 2010 Mar;16(1):49-57.
    PMID: 20413412
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  1. Long-acting beta2-agonists in adult asthma and the pattern of risk of death and severe asthma outcomes: a study with the General Practice Research Database.
    de Vries F, Setakis E, Zhang B, van Staa TP.
    Eur Respir J. 2010 Mar 29.
    PMID: 20351036
  2. Declining 1-year case-fatality of stroke and increasing coverage of vascular risk management:population-based cohort study.
    Gulliford MC, Charlton J, Rudd A, Wolfe CD, Toschke AM.
    J Neurol Neurosurg Psychiatry. 2010 Apr;81(4):416-22.
    PMID: 20176596
  3. Chronic obstructive pulmonary disease and the risk of cardiovascular diseases.
    Schneider C, Bothner U, Jick SS, Meier CR.
    Eur J Epidemiol. 2010 Apr;25(4):253-60.
    PMID: 20191376
  4. Non-steroidal anti-inflammatory drugs and pancreatic cancer risk: a nested case-control study.
    Bradley MC, Hughes CM, Cantwell MM, Napolitano G, Murray LJ.
    Br J Cancer. 2010 Apr 27;102(9):1415-21.
    PMID: 20372155
  5. Epidemiology of paediatric immune thrombocytopenia in the General Practice Research Database.
    Yong M, Schoonen WM, Li L, Kanas G, Coalson J, Mowat F, Fryzek J, Kaye JA.
    Br J Haematol. 2010 Apr 4.
    PMID: 20377590
  6. Healthcare expenditure in severely depressed patients treated with escitalopram, generic SSRIs or venlafaxine in the UK.
    Wade AG, Saragoussi D, Despiégel N, François C, Guelfucci F, Toumi M.
    Curr Med Res Opin. 2010 May;26(5):1161-70.
    PMID: 20297951
  7. Laboratory monitoring and adverse patient outcomes with antihypertensive therapy in primary care.
    McDowell SE, Coleman JJ, Evans SJ, Gill PS, Ferner RE
    Pharmacoepidemiol Drug Saf. 2010 May;19(5):482-9.
    PMID: 20306453
  8. Prescribing patterns of asthma controller therapy for children in UK primary care: a cross-sectional observational study.
    Thomas M, Murray-Thomas T, Fan T, Williams T, Taylor S.
    BMC Pulm Med. 2010 May 14;10:29.
    PMID: 20470409
  9. Measles in the United Kingdom 1990-2008 and the effectiveness of measles vaccines.
    Jick H, Hagberg KW.
    Vaccine. 2010 May 12.
    PMID: 20470793
  10. Rhythm control agents and adverse events in patients with atrial fibrillation.
    Taylor CJ, Hodgkinson J, Hobbs FD.
    Int J Clin Pract. 2010 May 12.
    PMID: 20487051
  11. Heart failure, myocardial infarction, lung cancer and death in COPD patients: A UK primary care study.
    García Rodríguez LA, Wallander MA, Martín-Merino E, Johansson S.
    Respir Med. 2010 May 17.
    PMID: 20483577
  12. Long-term metformin use is associated with decreased risk of breast cancer.
    Bodmer M, Meier C, Krähenbühl S, Jick SS, Meier CR.
    Diabetes Care. 2010 Jun;33(6):1304-8.
    PMID: 20299480
  13. Treatment of type 2 diabetes and outcomes in patients with heart failure: a nested case-control study from the U.K. General Practice Research Database.
    MacDonald MR, Eurich DT, Majumdar SR, Lewsey JD, Bhagra S, Jhund PS, Petrie MC, McMurray JJ, Petrie JR, McAlister FA.
    Diabetes Care. 2010 Jun;33(6):1213-8.
    PMID: 20299488
  14. Reflux disease, gastrointestinal ulcer or weight loss in patients with COPD.
    Schneider C, Jick SS, Bothner U, Meier CR.
    COPD. 2010 Jun;7(3):172-8.
    PMID: 20486815
  15. Transdermal and oral hormone replacement therapy and the risk of stroke: a nested case-control study.
    Renoux C, Dell'aniello S, Garbe E, Suissa S.
    BMJ.2010 Jun 3;340:c2519.
    PMID: 20525678
  16. Menopause-related workload in general practice 1996-2005: a retrospective study in the UK.
    Iversen L, Delaney EK, Hannaford PC, Black C.
    Fam Pract. 2010 Jun 7.
    PMID: 20530133.
  17. Oversight: a retrospective study of biochemical monitoring in patients beginning antihypertensive drug treatment in primary care.
    Coleman JJ, McDowell SE, Evans SJ, Gill PS, Ferner RE.
    Br J Clin Pharmacol. 2010 Jul;70(1):109-17.
    PMID: 20642553
  18. Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior.
    Andersohn F, Schade R, Willich SN, Garbe E.
    Neurology. 2010 Jul 27;75(4):335-40.
    PMID: 20660863
  19. Risk of incident depression in patients with Parkinson disease in the UK.
    Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
    Eur J Neurol. 2010 Aug 16. [Epub ahead of print]
    PMID: 20722714
  20. The risk of depression, anxiety, and suicidality in patients with psoriasis: a population-based cohort study.
    Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM.
    Arch Dermatol. 2010 Aug;146(8):891-5.
    PMID: 20713823
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  1. Exposure to oral bisphosphonates and risk of esophageal cancer.
    Cardwell CR, Abnet CC, Cantwell MM, Murray LJ.
    JAMA. 2010 Aug 11;304(6):657-63.
    PMID: 20699457
  2. Risk of ischemic stroke in patients with Crohn's disease: a population-based nested case-control study.
    Andersohn F, Waring M, Garbe E.
    Inflamm Bowel Dis.2010 Aug;16(8):1387-92.
    PMID: 20014016
  3. Concomitant use of ibuprofen and paracetamol and the risk of major clinical safety outcomes.
    de Vries F, Setakis E, van Staa TP.
    Br J Clin Pharmacol. 2010 Sep;70(3):429-38.
    PMID: 20716244
  4. Identifying major congenital malformations in the UK General Practice Research Database (GPRD): a study reporting on the sensitivity and added value of photocopied medical records and free text in the GPRD.
    Charlton RA, Weil JG, Cunnington MC, de Vries CS.
    Drug Saf. 2010 Sep 1;33(9):741-50.
    PMID: 20701407
  5. Hospitalization risk in a type 2 diabetes cohort.
    Ng E, McGrail KM, Johnson JA.
    Health Rep. 2010 Sep;21(3):29-35.
    PMID: 20973431
  6. Concurrent use of tamoxifen with CYP2D6 inhibitors and the risk of breast cancer recurrence.
    Azoulay L, Dell'aniello S, Huiart L, du Fort GG, Suissa S.
    Breast Cancer Res Treat. 2010 Sep 17. [Epub ahead of print]
    PMID: 20848186
  7. Quality of care for chronic diseases in a British cohort of long-term cancer survivors.
    Khan NF, Mant D, Rose PW.
    Ann Fam Med. 2010 Sep-Oct;8(5):418-24.
    PMID: 20843883
  8. Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: case-control analysis within a UK primary care cohort.
    Green J, Czanner G, Reeves G, Watson J, Wise L, Beral V.
    BMJ. 2010 Sep 1;341:c4444.
    PMID: 20813820
  9. Identifying major congenital malformations in the UK General Practice Research Database (GPRD): a study reporting on the sensitivity and added value of photocopied medical records and free text in the GPRD.
    Charlton RA, Weil JG, Cunnington MC, de Vries CS.
    Drug Saf. 2010 Sep 1;33(9):741-50.
    PMID: 20701407
  10. Patients with type 2 diabetes mellitus have higher risk for acute pancreatitis compared with those without diabetes.
    Girman CJ, Kou TD, Cai B, Alexander CM, O'Neill EA, Williams-Herman DE, Katz L.
    Diabetes Obes Metab. 2010 Sep;12(9):766-71.
    PMID: 20649628
  11. Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K.
    Abuabara K, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM.
    Br J Dermatol. 2010 Sep;163(3):586-92.
    PMID: 20633008
  12. A comparison of risk stratification schema for stroke in 79884 atrial fibrillation patients in general practice.
    Van Staa TP, Setakis E, Di Tanna GL, Lane DA, Lip GY.
    J Thromb Haemost. 2010 Oct 1. [Epub ahead of print]
    PMID: 21029359.
  13. Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK General Practice Research Database.
    Cornish R, Macleod J, Strang J, Vickerman P, Hickman M.
    BMJ. 2010 Oct 26;341:c5475.
    PMID: 20978062
  14. Management of first-episode pelvic inflammatory disease in primary care: results from a large UK primary care database.
    Nicholson A, Rait G, Murray-Thomas T, Hughes G, Mercer CH, Cassell J.
    Br J Gen Pract. 2010 Oct;60(579):e395-406.
    PMID: 20883614
  15. Management of epididymo-orchitis in primary care: results from a large UK primary care database.
    Nicholson A, Rait G, Murray-Thomas T, Hughes G, Mercer CH, Cassell J.
    Br J Gen Pract. 2010 Oct;60(579):e407-22.
    PMID: 20883615
  16. Influenza vaccination, pneumococcal vaccination and risk of acute myocardial infarction: matched case-control study.
    Siriwardena AN, Gwini SM, Coupland CA.
    CMAJ. 2010 Oct 19;182(15):1617-23. Epub 2010 Sep 20.
    PMID: 20855479
  17. Mortality in Wegener's granulomatosis: a bimodal pattern.
    Luqmani R, Suppiah R, Edwards CJ, Phillip R, Maskell J, Culliford D, Jayne D, Morishita K, Arden N.
    Rheumatology (Oxford). 2010 Nov 25. [Epub ahead of print]
    PMID: 21112869
  18. Use of depot medroxyprogesterone acetate and fracture risk.
    Meier C, Brauchli YB, Jick SS, Kraenzlin ME, Meier CR.
    J Clin Endocrinol Metab. 2010 Nov;95(11):4909-16. Epub 2010 Aug 4.
    PMID: 20685865
  19. Statins and pancreatic cancer risk: a nested case-control study.
    Bradley MC, Hughes CM, Cantwell MM, Murray LJ.
    Cancer Causes Control. 2010 Dec;21(12):2093-100.
    PMID: 20697797.
  20. Safety of Topical Corticosteroids in Pregnancy: A Population-Based Cohort Study.
    Chi CC, Mayon-White RT, Wojnarowska FT.
    J Invest Dermatol. 2010 Dec 30. [Epub ahead of print]
    PMID: 21191410
  21. Developing and testing search strategies to identify patients with active seasonal allergic rhinitis in general practice
    Hammersley V, Flint R, Pinnock H, Sheikh A.
    Prim Care Respir J. 2010 Dec 28. [Epub ahead of print]
    PMID: 21190011
  22. Epidemiology of paediatric immune thrombocytopenia in the General Practice Research Database.
    Yong M, Schoonen WM, Li L, Kanas G, Coalson J, Mowat F, Fryzek J, Kaye JA.
    Br J Haematol. 2010 Jun;149(6):855-64. Epub 2010 Apr 4.
    PMID: 20377590
  23. Secular trends of antibacterial prescribing in UK paediatric primary care.
    Schneider-Lindner V, Quach C, Hanley JA, Suissa S.
    J Antimicrob Chemother. 2010 Dec 10. [Epub ahead of print]
    PMID: 21172784
  24. Long-term use of fluticasone propionate/salmeterol fixed-dose combination and incidence of nonvertebral fractures among patients with COPD in the UK General Practice Research Database.
    Miller DP, Watkins SE, Sampson T, Davis KJ.
    Phys Sportsmed. 2010 Dec;38(4):19-27.
    PMID: 21150138
  25. Metformin and the incidence of prostate cancer in patients with type 2 diabetes.
    Azoulay L, Dell'aniello S, Gagnon B, Pollak MN, Suissa S.
    Cancer Epidemiol Biomarkers Prev. 2010 Dec 10. [Epub ahead of print]
    PMID: 21148757
  26. Impact of Treatment Success on Health Service Use and Cost in Depression: Longitudinal Database Analysis.
    Byford S, Barrett B, Despiégel N, Wade A.
    Pharmacoeconomics. 2010 Dec 10. [Epub ahead of print]
    PMID: 21142289
  27. Effectiveness of influenza vaccination in the United kingdom, 1996-2007.
    Jick H, Hagberg KW.
    Pharmacotherapy. 2010 Dec;30(12):1199-206.
    PMID: 21114386
  28. The rate of decompensation and clinical progression of disease in people with cirrhosis: a cohort study.
    Fleming KM, Aithal GP, Card TR, West J. Aliment
    Pharmacol Ther. 2010 Dec;32(11-12):1343-50. Epub 2010 Oct 4.
    PMID: 21050236
  29. Consulting and prescribing behaviour for anxiety and depression in long-term survivors of cancer in the UK.
    Khan NF, Ward AM, Watson E, Rose PW.
    Eur J Cancer. 2010 Dec;46(18):3339-44.Epub 2010 Aug 18.
    PMID: 20727734
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Research Papers - 2009

  1. The epidemiology of haemochromatosis: a population-based study
    Crooks CJ, West J, Solaymani-Dodaran M, Card TR
    Aliment Pharmacol Ther. 2009 Jan 15;29(2):183-92. Epub 2008 Oct 20
    PMID: 18945251
  2. The risk of venous thromboembolism associated with the use of tranexamic acid and other drugs used to treat menorrhagia:
    a case-control study using the General Practice Research Database
    Sundström A, Seaman H, Kieler H, Alfredsson L.
    BJOG. 2009 Jan;116(1):91-7. Epub 2008 Nov 11.
    PMID: 19016686
  3. Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control.
    Thomas M, Price D, Chrystyn H, Lloyd A, Williams AE, von Ziegenweidt J.
    BMC Pulm Med. 2009 Jan 2;9:1
    PMID: 19121204
  4. Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis.
    Brauchli YB, Jick SS, Miret M, Meier CR.
    Br J Dermatol. 2009 Jan 28. [Epub ahead of print]
    PMID: 19210501
  5. Prescribing trends in asthma: a longitudinal observational study.
    Turner S, Thomas M, von Ziegenweidt J, Price D.
    Arch Dis Child. 2009 Jan;94(1):16-22. Epub 2008 Aug 13.
    PMID: 18701558
  6. The potential effects on fracture outcomes of improvements in persistence and compliance with bisphosphonates.
    Rietbrock S, Olson M, van Staa TP.
    QJM. 2009 Jan;102(1):35-42. Epub 2008 Oct 8.
    PMID: 18842684
  7. Traditional versus marginal structural models to estimate the effectiveness of beta-blocker use on mortality after myocardial infarction.
    Delaney JA, Daskalopoulou SS, Suissa S.
    Pharmacoepidemiol Drug Saf. 2009 Jan;18(1):1-6.
    PMID: 18949804
  8. Study of adverse outcomes in women using testosterone therapy.
    van Staa TP, Sprafka JM.
    Maturitas. 2009 Jan 20;62(1):76-80. Epub 2008 Dec 24.
    PMID: 19108962
  9. Use of primary care electronic medical record database in drug efficacy research on cardiovascular outcomes: comparison of database and randomised controlled trial findings.
    Tannen RL, Weiner MG, Xie D.
    BMJ. 2009 Jan 27;338:b81.
    PMID: 19174434
  10. Investigation of the temporal association of Guillain-Barre syndrome with influenza vaccine and influenzalike illness using the United Kingdom General Practice Research Database.
    Stowe J, Andrews N, Wise L, Miller E.
    Am J Epidemiol. 2009 Feb 1;169(3):382-8. Epub 2008 Nov 24.
    PMID: 19033158
  11. Is relative mortality of type 2 diabetes mellitus decreasing?. Gulliford MC, Charlton J.
    Am J Epidemiol. 2009 Feb 15;169(4):455-61. Epub 2008 Nov 26.
    PMID: 19037005
  12. Rate of suicide in patients taking montelukast.
    Jick H, Hagberg KW, Egger P.
    Pharmacotherapy. 2009 Feb;29(2):165-6.
    PMID: 19170586
  13. Effect of antibiotics for otitis media on mastoiditis in children: a retrospective cohort study using the United kingdom general practice research database.
    Thompson PL, Gilbert RE, Long PF, Saxena S, Sharland M, Wong IC.
    Pediatrics. 2009 Feb;123(2):424-30.
    PMID: 19171605
  14. Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database.
    Marieke Schoonen W, Kucera G, Coalson J, Li L, Rutstein M, Mowat F, Fryzek J, Kaye JA.
    Br J Haematol. 2009 Feb 24. [Epub ahead of print]
    PMID: 19245432
  15. An increase in the prevalence of type 1 and 2 diabetes in children and adolescents: results from prescription data from a UK general practice database.
    Hsia Y, Neubert AC, Rani F, Viner RM, Hindmarsh PC, Wong IC.
    Br J Clin Pharmacol. 2009 Feb;67(2):242-9.
    PMID: 19260863
  16. Trends in drug misuse recorded in primary care in the UK from 1998 to 2005.
    Frisher M, Martino O, Crome I, Croft P.
    J Public Health (Oxf). 2009 Mar;31(1):69-73.
    PMID: 18836199
  17. Rise in psychotropic drug prescribing in children and adolescents during 1992-2001: a population-based study in the UK.
    Hsia Y, Maclennan K.
    Eur J Epidemiol. 2009;24(4):211-6.
    PMID: 19266290
  18. How effective are dose-adjusted warfarin and aspirin for the prevention of stroke in patients with chronic atrial fibrillation? An analysis of the UK General Practice Research Database.
    Rietbrock S, Plumb JM, Gallagher AM, van Staa TP.
    Thromb Haemost. 2009 Mar;101(3):527-34.
    PMID: 19277415
  19. Chest pain without established ischaemic heart disease in primary care patients: associated comorbidities and mortality.
    Ruigómez A, Massó-González EL, Johansson S, Wallander MA, García-Rodríguez LA.
    Br J Gen Pract. 2009 Mar;59(560):e78-86.
    PMID: 19275827
  20. Changing trends in antiepileptic drug prescribing in girls of child-bearing potential.
    Ackers R, Besag FM, Wade A, Murray ML, Wong IC. C
    Arch Dis Child. 2009 Mar 22.
    PMID: 19307197
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  1. Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis.
    Grosso A, Douglas I, Hingorani A, MacAllister R, Smeeth L.
    PLoS ONE. 2009;4(3):e4720.
    PMID: 19266096
  2. Attention-deficit hyperactivity disorder: treatment discontinuation in adolescents and young adults.
    McCarthy S, Asherson P, Coghill D, Hollis C, Murray M, Potts L, Sayal K, de Soysa R, Taylor E, Williams T, Wong IC.
    Br J Psychiatry. 2009 Mar;194(3):273-7.
    PMID: 19252159
  3. Are individuals with an autoimmune disease at higher risk of a second autoimmune disorder?
    Somers EC, Thomas SL, Smeeth L, Hall AJ.
    Am J Epidemiol. 2009 Mar 15;169(6):749-55. Epub 2009 Feb 18.
    PMID: 19224981
  4. Systematic review: the epidemiology of gastro-oesophageal reflux disease in primary care, using the UK General Practice Research Database.
    El-Serag H, Hill C, Jones R.
    Aliment Pharmacol Ther. 2009 Mar 1;29(5):470-80. Epub 2008 Nov 25.
    PMID: 19035977
  5. Fracture risk in patients receiving acid-suppressant medication alone and in combination with bisphosphonates.
    de Vries F, Cooper AL, Cockle SM, van Staa TP, Cooper C.
    Osteoporos Int. 2009 Mar 31. [Epub ahead of print]
    PMID:19333676
  6. Risk markers for both chronic fatigue and irritable bowel syndromes: a prospective case-control study in primary care.
    Hamilton WT, Gallagher AM, Thomas JM, White PD.
    Psychol Med. 2009 Apr 15:1-9. [Epub ahead of print]
    PMID:19366500
  7. Establishing the incidence and prevalence of clinician-diagnosed allergic conditions in children and adolescents using routinely collected data from general practices.
    Punekar YS, Sheikh A.
    Clin Exp Allergy. 2009 Apr 17. [Epub ahead of print]
    PMID: 19400899
  8. A population-based study of perforated diverticular disease incidence and associated mortality.
    Humes DJ, Solaymani-Dodaran M, Fleming KM, Simpson J, Spiller RC, West J.
    Gastroenterology. 2009 Apr;136(4):1198-205. Epub 2008 Dec 27.
    PMID: 19185583
  9. Antidiabetic action of bezafibrate in a large observational database.
    Flory JH, Ellenberg S, Szapary PO, Strom BL, Hennessy S.
    Diabetes Care. 2009 Apr;32(4):547-51. Epub 2009 Jan 8.
    PMID: 19131462
  10. Combined oral contraceptive use and the risk of systemic lupus erythematosus.
    Bernier MO, Mikaeloff Y, Hudson M, Suissa S.
    Arthritis Rheum. 2009 Apr 15;61(4):476-81.
    PMID: 19333988
  11. Antibiotic Prescribing and Outcomes of Lower Respiratory Tract Infection in UK Primary Care.
    Winchester CC, Macfarlane T, Thomas M, Price D.
    Chest. 2009 Apr 10
    PMID: 19029433
  12. Lithium, antipsychotics, and risk of psoriasis.
    Brauchli YB, Jick SS, Curtin F, Meier CR.
    J Clin Psychopharmacol. 2009 Apr;29(2):134-40.
    PMID: 19512974
  13. Mortality associated with attention-deficit hyperactivity disorder (ADHD) drug treatment: a retrospective cohort study of children, adolescents and young adults using the general practice research database.
    McCarthy S, Cranswick N, Potts L, Taylor E, Wong IC.
    Drug Saf. 2009;32(11):1089-96.
    PMID: 19810780
  14. Comorbidities of idiopathic thrombocytopenic purpura: a population-based study.
    Feudjo-Tepie MA, Le Roux G, Beach KJ, Bennett D, Robinson NJ.
    Adv Hematol.2009;2009: 963506. Epub 2009 Apr 2.
    PMID: 19960044
  15. Antihypertensive treatment with ACE inhibitors or beta-blockers and risk of incident atrial fibrillation in a general hypertensive population.
    Heckbert SR, Wiggins KL, Glazer NL, Dublin S, Psaty BM, Smith NL, Longstreth WT Jr, Lumley T.
    Am J Hypertens. 2009 May;22(5):538-44. Epub 2009 Mar 5.
    PMID: 19265792
  16. Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus.
    Andersohn F, Schade R, Suissa S, Garbe E.
    Am J Psychiatry. 2009 May;166(5):591-8. Epub 2009 Apr 1.
    PMID: 19339356
  17. Rheumatoid arthritis in UK primary care: incidence and prior morbidity.
    Rodríguez LA, Tolosa LB, Ruigómez A, Johansson S, Wallander MA.
    Scand J Rheumatol. 2009 May-Jun;38(3):173-7.
    PMID: 19117247
  18. The effect of concurrent pain on the management of patients with depression: an analysis of NHS healthcare resource utilisation using the GPRD database.
    Watson L, Baird J, Hösel V, Peveler R.
    Int J Clin Pract. 2009 May;63(5):698-706. Epub 2009 Feb 24.
    PMID: 19243454
  19. Risk of cataract among idiopathic thrombocytopenic purpura patients in the UK general practice research database.
    Feudjo-Tepie MA, Hall SA, Logie J, Robinson NJ.
    Pharmacoepidemiol Drug Saf. 2009 May;18(5):380-5.
    PMID:19241439
  20. Psoriasis and Risk of Incident Cancer: An Inception Cohort Study with a Nested Case-Control Analysis
    Brauchli YB, Jick SS, Miret M, Meier CR.
    J Invest Dermatol. 2009 May 14. [Epub ahead of print]
    PMID: 19440219.
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  1. The Risk of Stroke in Patients with Psoriasis.
    Gelfand JM, Dommasch ED, Shin DB, Azfar RS, Kurd SK, Wang X, Troxel AB.
    J Invest Dermatol. 2009 May 21. [Epub ahead of print]
    PMID: 19458634.
  2. Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population-based study.
    Alonso A, Logroscino G, Jick SS, Hernán MA. Eur J
    Neurol. 2009 Jun;16(6):745-51.
    PMID: 19475756
  3. The epidemiology of Takayasu arteritis in the UK.
    Watts R, Al-Taiar A, Mooney J, Scott D, Macgregor A.
    Rheumatology (Oxford). 2009 Aug;48(8):1008-11. Epub 2009 Jun 19.
    PMID: 19542212
  4. Determining the date of diagnosis--is it a simple matter? The impact of different approaches to dating diagnosis on estimates of delayed care for ovarian cancer in UK primary care.
    Tate AR, Martin AG, Murray-Thomas T, Anderson SR, Cassell JA.
    BMC Med Res Methodol. 2009 Jun 23;9:42.
    PMID: 19549322
  5. Risk of cardiovascular outcomes in users of estradiol/dydrogesterone or other HRT preparations.
    Schneider C, Jick SS, Meier CR.
    Climacteric. 2009 Jun 26:1-9. [Epub ahead of print]
    PMID: 19565370
  6. Use of antidepressants and the risk of Parkinson's disease: a prospective study.
    Alonso A, Rodríguez LA, Logroscino G, Hernán MA.
    J Neurol Neurosurg Psychiatry. 2009 Jun;80(6):671-4.
    PMID: 19448091
  7. Antihypertensive treatment after stroke and all-cause mortality--an analysis of the General Practitioner Research Database (GPRD).
    Toschke AM, Wolfe CD, Heuschmann PU, Rudd AG, Gulliford M.
    Cerebrovasc Dis. 2009;28(2):105-11. Epub 2009 Jun 5.
    PMID: 19506368
  8. The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK.
    Cooper C, Steinbuch M, Stevenson R, Miday R, Watts NB.
    Osteoporos Int. 2009 Jun 23. [Epub ahead of print]
    PMID: 19547906.
  9. Assessing the impact of cannabis use on trends in diagnosed schizophrenia in the United Kingdom from 1996 to 2005.
    Frisher M, Crome I, Martino O, Croft P
    Schizophr Res. 2009 Jun 26. [Epub ahead of print]
    PMID: 19560900
  10. Trends in HIV testing and recording of HIV status in the UK primary care setting: a retrospective cohort study 1995-2005.
    Evans HE, Mercer CH, Rait G, Hamill M, Delpech V, Hughes G, Brook G, Williams T, Johnson AM, Singh S, Petersen I, Chadborn T, Cassell JA.
    Sex Transm Infect. 2009 Jun 29. [Epub ahead of print]
    PMID: 19564649
  11. Trends in the prescription of anti-diabetic medications in the United Kingdom: a population-based analysis.
    Filion KB, Joseph L, Boivin JF, Suissa S, Brophy JM.
    Pharmacoepidemiol Drug Saf. 2009 Jul 20. [Epub aheadof print]
    PMID: 19621344
  12. The pattern of risk of myocardial infarction in patients taking asthma medication: a study with the General Practice Research Database.
    J Zhang B, de Vries F, Setakis E, van Staa TP.
    Hypertens. 2009 Jul;27(7):1485-92.
    PMID: 19491706
  13. The Origin and Spread of a Mumps Epidemic: United Kingdom, 2003-2006.
    Jick H, Chamberlin DP, Hagberg KW.
    Epidemiology. 2009 Jul 10. [Epub ahead of print]
    PMID: 19593154
  14. Risk of stroke in patients with idiopathic Parkinson disease.
    Becker C, Jick SS, Meier CR.
    Parkinsonism Relat Disord. 2009 Jul 27. [Epub ahead of print]
    PMID: 19640771
  15. Incidence and mortality of falls amongst older people in primary care in the United Kingdom.
    Gribbin J, Hubbard R, Smith C, Gladman J, Lewis S.
    QJM. 2009 Jul;102(7):477-83. Epub 2009 Jun 5.
    PMID: 19502289.
  16. The risk of unintended pregnancies in users of the contraceptive patch compared to users of oral contraceptives in the UK General Practice Research Database.
    Jick SS, Hagberg KW, Kaye JA, Jick H.
    Contraception. 2009 Aug;80(2):142-51. 2009 Apr 25.
    PMID: 19631789
  17. Alarm symptoms and identification of non-cancer diagnoses in primary care: cohort study.
    Jones R, Charlton J, Latinovic R, Gulliford MC.
    BMJ. 2009 Aug 13;339:b3094. doi: 10.1136/bmj.b3094.
    PMID: 19679615
  18. Utilization characteristics and treatment persistence in patients prescribed low-dose buprenorphine patches in primary care in the United Kingdom: a retrospective cohort study.
    Gallagher AM, Leighton-Scott J, van Staa TP.
    Clin Ther. 2009 Aug;31(8):1707-15.
    PMID: 19808129.
  19. Pay for perfomance and the quality of diabetes management in individuals with and without co-morbid medical conditions.
    Millett C, Bottle A, Ng A, Curcin V, Molokhia M, Saxena S, Majeed A.
    J R Soc Med. 2009 Sep;102(9):369-77.
    PMID: 19734534
  20. Recent trends in lung cancer and its association with COPD: an analysis using the UK GP Research Database.
    Kiri VA, Soriano J, Visick G, Fabbri L.
    Prim Care Respir J. 2009 Sep 15. pii: pcrj-2009-02-0021. doi: 10.4104/pcrj.2009.00048.
    [Epub ahead of print]
    PMID: 19756330.
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  1. Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care database.
    Gulliford MC, Charlton J, Ashworth M, Rudd AG, Toschke AM; eCRT Research Team.
    PLoS One. 2009 Sep 24;4(9):e7168.
    PMID: 19777060
  2. The risk of fractures associated with thiazolidinediones: a self-controlled case-series study.
    Douglas IJ, Evans SJ, Pocock S, Smeeth L.
    PLoS Med. 2009 Sep;6(9):e1000154. Epub 2009 Sep 29.
    PMID: 19787025
  3. Prevalence and incidence of Wegener's granulomatosis in the UK general practice research database.
    Watts RA, Al-Taiar A, Scott DG, Macgregor AJ.
    Prevalence and incidence of Arthritis Rheum. 2009 Oct 15;61(10):1412-6.
    PMID: 19790134
  4. Varenicline and suicidal behaviour: a cohort study based on data from the General Practice Research Database.
    Gunnell D, Irvine D, Wise L, Davies C, Martin RM.
    BMJ. 2009 Oct 1;339:b3805. doi: 10.1136/bmj.b3805.
    PMID: 19797344
  5. Chronic obstructive pulmonary disease and the risk of depression.
    Schneider C, Jick SS, Bothner U, Meier CR.
    Chest. 2009 Oct 3. [Epub ahead of print]
    PMID: 19801582
  6. Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database.
    Moore M, Yuen HM, Dunn N, Mullee MA, Maskell J, Kendrick T.
    BMJ. 2009 Oct 15;339:b3999. doi: 10.1136/bmj.b3999.
    Erratum in: BMJ. 2009;339:b4361.
    PMID: 19833707
  7. Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK General Practice Research Database.
    Breart G, Cooper C, Meyer O, Speirs C, Deltour N, Reginster JY.
    Osteoporos Int. 2009 Oct 6. [Epub ahead of print]
    PMID: 19806285.
  8. Cessation of attention deficit hyperactivity disorder drugs in the young (CADDY)--a pharmacoepidemiological and qualitative study.
    Wong IC, Asherson P, Bilbow A, Clifford S, Coghill D, DeSoysa R, Hollis C, McCarthy S, Murray M, Planner C, Potts L, Sayal K, Taylor E. Health Technol Assess. 2009
    Oct;13(50):iii-iv, ix-xi, 1-120.
    PMID: 19883527.
  9. Chronic obstructive pulmonary disease in UK primary care: incidence and risk factors.
    García Rodríguez LA, Wallander MA, Tolosa LB, Johansson S.
    COPD. 2009 Oct;6(5):369-79.
    PMID: 19863366
  10. Statin use and risk of gallstone disease followed by cholecystectomy.
    Bodmer M, Brauchli YB, Krähenbühl S, Jick SS, Meier CR.
    JAMA. 2009 Nov 11;302(18):2001-7.
    PMID: 19903921
  11. Inhaled tiotropium bromide and risk of stroke
    Grosso A, Douglas I, Hingorani AD, MacAllister R, Hubbard R, Smeeth L.
    Br J Clin Pharmacol. 2009, Nov;68(5):731-6.
    PMID: 19916997
  12. Cancer risk in association with Parkinson disease: A population-based study
    Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
    Parkinsonism Relat Disord. 2009 Nov 27. [Epub ahead of print]
    PMID: 19945903
  13. Selective decrease in consultations and antibiotic prescribing for acute respiratory tract infections in UK primary care up to 2006.
    Gulliford M, Latinovic R, Charlton J, Little P, van Staa T, Ashworth M.
    J Public Health (Oxf). 2009 Dec;31(4):512-20. Epub 2009 Sep 4.
    PMID: 19734168
  14. Prevalence of acute repetitive seizures (ARS) in the United Kingdom.
    Martinez C, Sullivan T, Hauser WA.
    Epilepsy Res. 2009 Dec;87(2-3):137-43. Epub 2009 Sep
    PMID: 19748226
  15. Establishing the sequential progression of multiple allergic diagnoses in a UK birth cohort using the General Practice Research Database.
    Punekar YS, Sheikh A.
    Clin Exp Allergy. 2009 Dec;39(12):1889-95. Epub 2009 Oct 7.
    PMID: 19817751
  16. Primary care consultations and costs among HIV-positive individuals in UK primary care 1995-2005: a cohort study.
    Evans HE, Tsourapas A, Mercer CH, Rait G, Bryan S, Hamill M, Delpech V, Hughes G, Brook G, Williams T, Johnson AM, Singh S, Petersen I, Chadborn T, Cassell JA.
    Sex Transm Infect. 2009 Dec; 85(7):543-9. Epub 2009 Oct 22.
    PMID: 19854699
  17. Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.
    Tzoulaki I, Molokhia M, Curcin V, Little MP, Millett CJ, Ng A, Hughes RI, Khunti K, Wilkins MR, Majeed A, Elliott P.
    BMJ. 2009 Dec 3;339:b4731
    PMID: 19959591
  18. What happens to new-onset headache in children that present to primary care? A case-cohort study using electronic primary care records.
    Kernick D, Stapley S, Campbell J, Hamilton W.
    Cephalalgia. 2009 Dec;29(12):1311-6.
    PMID: 19911465.
  19. Risk of ischemic stroke in patients with Crohn's disease: A population-based nested case-control study.
    Andersohn F, Waring M, Garbe E.
    Inflamm Bowel Dis. [Epub ahead of print]
    PMID: 20014016.
  20. Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database.
    Mehta NN, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM.
    Eur Heart J. 2009 Dec 27. [Epub ahead of print]
    PMID: 20037179
  21. Risk of gynecological cancers in users of estradiol/dydrogesterone or other HRT preparations.
    Schneider C, Jick SS, Meier CR. Climacteric.
    2009 Dec;12(6):514-24.
    PMID: 19905903
  22. A comparison of cost effectiveness using data from randomized trials or actual clinical practice: selective cox-2 inhibitors as an example.
    van Staa TP, Leufkens HG, Zhang B, Smeeth L. PLoS Med. 2009 Dec;6(12):e1000194.
    Epub 2009 Dec 8.
    PMID: 19997499
  23. Thiazolidinediones and the risk of incident strokes in patients with type 2 diabetes: a nested case-control study.
    Azoulay L, Schneider-Lindner V, Dell'aniello S, Filion KB, Suissa S.
    Pharmacoepidemiol Drug Saf. 2009 Dec 8. [Epub ahead of print]
    PMID: 19998318
  24. Hip Fracture Risk in Patients with a Diagnosis of Pernicious Anemia.
    Merriman NA, Putt ME, Metz DC, Yang YX.
    Gastroenterology. 2009 Dec 16. [Epub ahead of print]
    PMID: 20026065
  25. Cost effectiveness of travoprost versus a fixed combination of latanoprost/timolol in patients with ocular hypertension or glaucoma: analysis based on the UK general practitioner research database.
    De Natale R, Lafuma A, Berdeaux G.
    Clin Drug Investig. 2009;29(2):111-20.
    PMID: 19133706
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Research Papers - 2008

  1. Migraine incidence, comorbidity and health resource utilization in the UK.
    Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
    Cephalalgia. 2008 Jan;28(1):57-64. Epub 2007 Nov 6.
    PMID: 17986274
  2. The Risk of Newly Diagnosed Asthma in Migraineurs With or Without Previous Triptan Prescriptions
    Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
    Headache. 2008 Jan 11; [Epub ahead of print]
    PMID: 18194300
  3. Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: a population based case-control study.
    Brauchli YB, Jick SS, Curtin F, Meier CR.
    J Am Acad Dermatol. 2008 Jan 12; [Epub ahead of print]
    PMID: 18194825
  4. No association between routinely recorded infections in early life and subsequent risk of childhood-onset Type 1 diabetes: a matched case-control study using the UK General Practice Research Database.
    Cardwell CR, Carson DJ, Patterson CC.
    Diabet Med. 2008 Jan 14; [Epub ahead of print]
    PMID: 18201209
  5. Adverse events associated with prolonged antibiotic use.
    Meropol SB, Chan KA, Chen Z, Finkelstein JA, Hennessy S, Lautenbach E, Platt R, Schech SD, Shatin D, Metlay JP.
    Pharmacoepidemiol Drug Saf. 2008 Jan 24; [Epub ahead of print]
    PMID: 18215001
  6. Data Resources for Investigating Drug Exposure during Pregnancy and Associated Outcomes: The General Practice Research Database (GPRD) as an Alternative to Pregnancy Registries.
    Charlton RA, Cunnington MC, de Vries CS, Weil JG.
    Drug Saf. 2008;31(1):39-51.
    PMID: 18095745
  7. Is obesity associated with gastropharyngeal reflux disease?.
    Choi CW, Kim GH, Song CS, Wang SG, Lee BJ, I H, Kang DH, Song GA.
    World J Gastroenterol. 2008 Jan 14;14(2):265-71.
    PMID: 18186566
  8. Mortality after infection with methicillin resistant Staphylococcus aureus (MRSA) diagnosed in the community.
    Delaney JA, Schneider-Lindner V, Brassard P, Suissa S.
    BMC Med. 2008 Jan 31;6(1):2 [Epub ahead of print]
    PMID: 18234115
  9. Antidepressant drug use and risk of venous thromboembolism.
    Jick SS, Li L.
    Pharmacotherapy. 2008 Feb;28(2):144-50.
    PMID: 18225961
  10. Nonsteroidal anti-inflammatory drug use and the risk of severe skin and soft tissue complications in patients with varicella or zoster disease.
    Mikaeloff Y, Kezouh A, Suissa S.
    Br J Clin Pharmacol. 2008 Feb;65(2):203-9.
    PMID: 18251759
  11. Replicated studies of two randomized trials of angiotensin- converting enzyme inhibitors: further empiric validation of the 'prior event rate ratio' to adjust for unmeasured confounding by indication.
    Tannen RL, Weiner MG, Xie D.
    Pharmacoepidemiol Drug Saf. 2008 Mar 10;17(7):671-685. [Epub ahead of print]
    PMID: 18327852
  12. Replication of the Scandinavian Simvastatin Survival Study using a primary care medical record database prompted exploration of a new method to address unmeasured confounding.
    Weiner MG, Xie D, Tannen RL
    Pharmacoepidemiol Drug Saf. 2008 Mar 10;17(7):661-670. [Epub ahead of print]
    PMID: 18327857
  13. Prevalence and predictors of lipid abnormalities in patients treated with statins in the UK general practice.
    Phatak H, Wentworth C, Sazonov V, Burke T.
    Atherosclerosis. 2008 Mar 27. [Epub ahead of print]
    PMID: 18457840
  14. Infections presenting for clinical care in early life and later risk of hay fever in two uk birth cohorts.
    Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG
    Allergy. 2008 Mar;63(3):274-83.
    PMID: 18269673
  15. Individualizing the risks and benefits of postmenopausal hormone therapy.
    van Staa TP, Cooper C, Barlow D, Leufkens HG.
    Menopause. 2008 Mar-Apr;15(2):374-81.
    PMID: 17882009
  16. What is the harm-benefit ratio of Cox-2 inhibitors?
    van Staa TP, Smeeth L, Persson I, Parkinson J, Leufkens HG.
    Int J Epidemiol. 2008 Apr;37(2):405-13. Epub 2008 Feb 8.
    PMID: 18263647
  17. Onset of acute myocardial infarction after use of non-steroidal anti-inflammatory drugs.
    Hammad TA, Graham DJ, Staffa JA, Kornegay CJ, Dal Pan GJ
    Pharmacoepidemiol Drug Saf. 2008 Apr;17(4):315-21.
    PMID: 18302311
  18. Chronic statin therapy and the risk of colorectal cancer.
    Yang YX, Hennessy S, Propert K, Hwang WT, Sarkar M, Lewis JD.
    Pharmacoepidemiol Drug Saf. 2008 Apr 16. [Epub ahead of print]
    PMID: 18412290
  19. The safety of rosuvastatin in comparison with other statins in over 100 000
    García-Rodríguez LA, Gonzalez EM, Wallander MA, Johansson S.
    Pharmacoepidemiol Drug Saf. 2008 Apr 21. [Epub ahead of print]
    PMID: 18425988
  20. Use of thiazolidinediones and fracture risk.
    16: Meier C, Kraenzlin ME, Bodmer M, Jick SS, Jick H, Meier CR.
    Arch Intern Med. 2008 Apr 28;168(8):820-5.
    PMID: 18443256
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  1. Evaluating drug toxicity signals: is a hierarchical classification of evidence useful or a hindrance?
    van Staa TP, Smeeth L, Persson I, Parkinson J, Leufkens HG.
    Pharmacoepidemiol Drug Saf. 2008 May;17(5):475-84.
    PMID: 18322905
  2. Validation of neural tube defects in the full featured--general practice research database.
    Devine S, West SL, Andrews E, Tennis P, Eaton S, Thorp J, Olshan A.
    Pharmacoepidemiol Drug Saf. 2008 May;17(5):434-44.
    PMID: 18344214
  3. Use of statins and the risk of Parkinson's disease: a retrospective case-control study in the UK.
    Becker C, Jick SS, Meier CR.
    Drug Saf. 2008;31(5):399-407.
    PMID: 18422380
  4. Epidemiologic features of antipsychotic prescribing to children and adolescents in primary care in the United Kingdom.
    Rani F, Murray ML, Byrne PJ, Wong IC
    Pediatrics. 2008 May;121(5):1002-9.
    PMID: 18450906
  5. Epidemiology and cost of herpes zoster and post-herpetic neuralgia in the United Kingdom.
    Gauthier A, Breuer J, Carrington D, Martin M, Rémy V.
    Epidemiol Infect. 2008 May 9:1-10. [Epub ahead of print]
    PMID: 18466661
  6. Lipid Testing among Patients Beginning Statin Therapy in General Practice in the United Kingdom.
    Phatak H, Wentworth C, Burke TA
    Value Health. 2008 May 16. [Epub ahead of print]
    PMID: 18489501
  7. Fracture Outcomes Related to Persistence and Compliance with Oral Bisphosphonates.
    Gallagher A, Rietbrock S, Olson M, van Staa T.
    J Bone Miner Res. 2008 May 27. [Epub ahead of print]
    PMID: 18505366
  8. Low identification of alcohol use disorders in general practice in England.
    Cheeta S, Drummond C, Oyefeso A, Phillips T, Deluca P, Perryman K, Coulton S.
    Addiction. 2008 May;103(5):766-73.
    PMID: 18412755
  9. Explaining the decline in early mortality in men and women with type 2 diabetes. Population-based cohort study.
    Charlton J, Latinovic R, Gulliford MC.
    Diabetes Care. 2008 May 28. [Epub ahead of print]
    PMID: 18509209
  10. Costs and persistence of carbonic anhydrase inhibitor versus alpha-2 agonists, associated with beta-blockers, in glaucoma and ocular hypertension: an analysis of the UK-GPRD database.
    Lafuma A, Berdeaux G.
    Curr Med Res Opin. 2008 May;24(5):1519-27. Epub 2008 Apr 14.
    PMID: 18413015
  11. Validating the effects of drug treatment on blood pressure in the General Practice Research Database.
    Delaney JA, Moodie EE, Suissa S.
    Pharmacoepidemiol Drug Saf. 2008 Jun;17(6):535-45.
    PMID: 18265414
  12. Comparison of tiotropium bromide and combined ipratropium/salbutamol for the treatment of COPD: a UK General Practice Research Database 12-month follow-up study.
    Griffin J, Lee S, Caiado M, Kesten S, Price D.
    Prim Care Respir J. 2008 Jun;17(2):104-10.
    PMID: 18385913
  13. Association between beta-blockers, other antihypertensive drugs and psoriasis: population-based case-control study.
    Brauchli YB, Jick SS, Curtin F, Meier CR.
    Br J Dermatol. 2008 Jun;158(6):1299-307. Epub 2008 Apr 10.
    PMID: 18410416
  14. Incidence and mortality of primary sclerosing cholangitis in the UK: a population-based cohort study.
    Card TR, Solaymani-Dodaran M, West J.
    J Hepatol. 2008 Jun;48(6):939-44. Epub 2008 Mar 31.
    PMID: 18433916
  15. Immunosuppressant medications and mortality in inflammatory bowel disease.
    Lewis JD, Gelfand JM, Troxel AB, Forde KA, Newcomb C, Kim H, Margolis DJ, Strom BL
    Am J Gastroenterol. 2008 Jun;103(6):1428-35; quiz 1436. Epub 2008 May 20.
    PMID: 18494836
  16. Diabetes mellitus in patients with idiopathic Parkinson's disease.
    Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
    Diabetes Care. 2008 Jun 16. [Epub ahead of print]
    PMID: 18559656
  17. Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database.
    Petersen I, Johnson AM, Islam A, Duckworth G, Livermore DM, Hayward AC.
    Clin Otolaryngol. 2008 Jun;33(3):252.
    PMID: 18559032
  18. Initiation and persistence of warfarin or aspirin in patients with chronic atrial fibrillation in general practice: do the appropriate patients receive stroke prophylaxis
    Gallagher A, Rietbrock S, Plumb J, van Staa TP
    J Thromb Haemost. 2008 Sep;6(9):1500-6. Epub 2008 Jun 28
    PMID: 18573187
  19. Risk of myocardial infarction in men and women with type 2 diabetes in the UK: a cohort study using the General Practice Research Database.
    Mulnier HE, Seaman HE, Raleigh VS, Soedamah-Muthu SS, Colhoun HM, Lawrenson RA, de Vries CS.
    Diabetologia. 2008 Jun 26. [Epub ahead of print]
    PMID: 18581091
  20. Discontinuation of statin therapy following an acute myocardial infarction: a population-based study.
    Daskalopoulou SS, Delaney JA, Filion KB,Brophy JM, Mayo NE, Suissa S.
    Eur Heart J. 2008 Jul 29. [Epub ahead of print]
    PMID: 18664465
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  1. Gastro-intestinal haemorrhage risks of selective serotonin receptor antagonist therapy: a new look.
    Opatrny L, Delaney JA, Suissa S.
    Br J Clin Pharmacol. 2008 Jul;66(1):76-81. Epub 2008 May 6.
    PMID: 18460039
  2. Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification scheme.
    Rietbrock S, Heeley E, Plumb J, van Staa T.
    Am Heart J. 2008 Jul;156(1):57-64.
    PMID: 18585497
  3. Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy: interaction with nonsteroidal anti-inflammatory drugs and effect of acid-suppressing agents.
    de Abajo FJ, García-Rodríguez LA
    Arch Gen Psychiatry. 2008 Jul;65(7):795-803.
    PMID: 18606952
  4. Obesity and the use of insulin: a study of patients with type 2 diabetes in the UK.
    Yurgin N, Secnik K, Lage MJ
    J Diabetes Complications. 2008 Jul-Aug;22(4):235-40. Epub 2008 Apr 16.
    PMID: 18413211
  5. Risk of Cardiovascular and Cerebrovascular Events in Primary Billiary Cirrhosis: A population-Based Cohort Study
    Solaymani-Dodaran M, Aithal GP, Card T, West J.
    Am J Gastroenterol. 2008 Aug 27
    PMID: 18759822
  6. Proton pump inhibitor use and risk of hip fractures in patients without major risk factors.
    Kaye JA, Jick H.
    Pharmacotherapy. 2008 Aug;28(8):951-9.
    PMID: 18657011
  7. Changes in the characteristics of patients prescribes selective cyclooxygenase 2 inhibitors after the 2004 withdrawal of rofecoxib
    Setakis E, Leufkens HG, van Staa TP
    Arthritis Rheum. 2008 Aug 15;59(8): 1105-11
    PMID: 18668614
  8. Relationship Between Gastroesophageal Reflux Disease and COPD in UK Primary Care.
    Garcia Rodriuez LA, Martin-Merino E, Johansson S, Wallander MA,
    Chest. 2008 Aug 8
    PMID: 18689591
  9. Irritable Bowel Syndrome and Gastroesophagael Reflux Disease in Primary Care. Is there a link?
    Ruigomez A, Wallander MA, Johansson S, Rodriguez LA.
    Dig Dis Sci.2008 Aug 22
    PMID: 18720002
  10. Prescribing trends in asthma: a longitudinal observational study.
    Turner SW, Thomas M, von Ziegenweidt J, Price D.
    Arch Dis Child. 2008 Aug13.
    PMID: 18701558
  11. Risk of myocardial infarction and overall mortality in survivors of venous thrombolism
    Huerta C, Johansson S, Wallander MA, Rodriguez LA
    Thrombo J 2008 Aug 18; 6:10
    PMID: 18706117
  12. Exposure to antipsychotics and risk of stroke: self controlled case series study.
    Douglas IJ, Smeeth L.
    BMJ. 2008 Aug 28;337:al1227.doi: 10.1136/bmj.a1227
    PMID: 18755769
  13. Sex- and age-specific incidence of fractures in mental illness: a historical, population-based cohort study.
    Abel KM, Heatlie HF, Howard LM, Webb RT.
    J Clin Psychiatry. 2008 Sep;69(9):1398-403.
    PMID: 19193340.
  14. Has UK guidance affected general practitioner antibiotic prescribing for otitis media in children?
    Thompson PL, Gilbert RE, Long PF, Saxena S, Sharland M, Wong IC.
    J Public Health (Oxf). 2008 Sep 1. [Epub ahead of print]
    PMID 18765405
  15. Psoriasis and the risk of incident diabetes mellitus: a population-based study
    Brauchli YB, Jick SS, Meier CR.
    Br J Dermatol. 2008 Sept 6.
    PMID: 18782318
  16. Age-related Macular Degeneration and Complement Activation-Related Disease A. Population-Based Case-Control Study
    Nitsch D, Douglas I, Smeeth L, Fletcher A
    Ophthalmology. 2008 Sep 16. [Epub ahead of print]
    PMID: 18801575
  17. How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the general practice research database?
    Thomas SL, Edwards CJ, Smeeth L, Cooper C, Hall AJ.
    Arthritis Rheum.2008 Sep 15;59 (9): 1314-21
    PMID: 18759262
  18. Endometriosis and its coexistence with irritable bowel syndrome and pelvic inflammatory disease: findings from a national case-control study-Part 2.
    Seaman HE, Ballard KD, Wright JT, de Vries CS.
    BJOG 2008 Oct; 115(11): 1392-6. Epub 2008 Aug 19
    PMID: 18715239
  19. Psychiatric and cardiovascular comorbidities in patients with diabetes mellitus starting antiobesity drugs.
    Willemen MJ, Mantel-Teeuwisse AK, Straus SM, Leufkens HG, Egberts AC.
    Obesity (Silver Spring) 2008 Oct; 16(10):2331-5 Epub 2008 Jul 24
    PMID: 18719629
  20. Traditional versus marginal structural models to estimate the effectiveness of beta-blocker use on mortality after myocardial infarction.
    Delaney JA, Daskalopoulou MD Phd SS, Suissa S
    Pharmacoepidemiol Drug Saf. 2008 Oct 23
    PMID: 18949804
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  1. Panic disorder and risk of new onset coronary heart disease, acute myocardial infarction, and cardiac mortality: cohort study using the general practice research database.
    Walters K, Rait G, Petersen I, Williams R, Nazareth
    Eur Heart J 2008 Oct 23
    PMID: 18948354
  2. Trends in drug misuse recorded in primary care in the UK from 1998 to 2005.
    Frisher M, Martino O, Crome I, Croft P.
    J Public Health (Oxf). 2008 Oct 4. [Epub ahead of print]
    PMID: 1883619
  3. The potential effects on fracture outcomes of improvements in persistence and compliance with bisphosphonates
    Reitbrock S, Olson M, Van Staa TP
    QJM.2008 Oct 8.
    PMID: 18842684
  4. Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?.
    van Staa TP, Rietbrock S, Setakis E, Leufkens HG.
    J Intern Med. 2008 Nov;264(5):481-92. Epub 2008 Jun 25.
    PMID: 18624902.
  5. High do es inhaled corticosteroids versus add-on long-acting beta-agonists in asthma: An observational study.
    Thomas M, von Ziegenweidt J, Lee AJ, Price D.
    J Allergy Clin Immunol. 2008 Nov 3.
    PMID 18986690
  6. Hormone replacement therapy use and the risk of stroke
    Renoux C, Dell’aniello S, Garbe E, Suissa S.
    Maturitas. 2008 Nov 7 {Epub ahead of print}
    PMID: 18996656
  7. Infections in early life and childhood leukaemia risk: a UK case-control study of general practitioner records
    Cardwell cR, McKinney PA, Patterson CC. Murray LJ.
    Br J Cancer. 2008 Nov 4; 99 (9) : 1529-33. Epub 2008 Sep 30.
    PMID 18827817
  8. Determing the predictive value of Read/OXMIS codes to identify incident acute myocardial infarction in the General Practice Database.
    Hammad TA, McAdams MA, Feight A, Iyasu S, Dal Pan GJ.
    Pharmacoepidemiol Drug Saf. 2008 Nov 4
    PMID: 18985705
  9. Malignancies in the rheumatoid arthritis abatacept clinical development program: An epidemiological assessment.
    Simon TA, Smitten AL, Franklin J, Askling J, Lacaille D, Wolfe F, Hochberg MC, Qi K, Suissa S.
    Ann Rheum Dis. 2008 Dec 3.[Epub ahead of print]
    PMID: 19054822
  10. Use of hormonal contraceptive methods by women with diabetes.
    Shawe J, Mulnier H, Nicholls P, Lawrenson R.
    Prim Care Diabetes. 2008 Dec;2(4):195-9. Epub 2008 Nov 18.
    PMID: 19019754
  11. Costs and persistence of brimonidine versus brinzolamide in everyday glaucoma care: an analysis conducted on the UK General Practitioner Research Database.
    Lafuma A, Laurendeau C, Berdeaux G
    J Med Econ. 2008;11(3):485-97.
    PMID: 19450100
  12. Costs and persistence of alpha-2 adrenergic agonists versus carbonic anhydrase inhibitors, both associated with prostaglandin analogues, for glaucoma as recorded by The United Kingdom General Practitioner Research Database.
    Denis P, Lafuma A, Berdeaux G.
    Clin Ophthalmol. 2008 Jun;2(2):321-9.
    PMID: 19668723
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Research Papers - 2007

  1. Use of antibiotics for sore throat and incidence of quinsy.
    Dunn N, Lane D, Everitt H, Little P.
    Br J Gen Pract. 2007 Jan;57(534):45-9.
    PMID: 17244424
  2. Incidence of skeletal complications during treatment of childhood acute lymphoblastic leukemia: comparison of fracture risk with the General Practice Research Database.
    Hogler W, Wehl G, van Staa T, Meister B, Klein-Franke A, Kropshofer G.
    Pediatr Blood Cancer. 2007 Jan;48(1):21-7.
    PMID: 16317756
  3. Fracture risk with intermittent high-dose oral glucocorticoid therapy.
    De Vries F, Bracke M, Leufkens HG, Lammers JW, Cooper C, Van Staa TP.
    Arthritis Rheum. 2007 Jan;56(1):208-14.
    PMID: 17195223
  4. Dopamine agonists and the risk of cardiac-valve regurgitation.
    Schade R, Andersohn F, Suissa S, Haverkamp W, Garbe E.
    N Engl J Med. 2007 Jan 4;356(1):29-38.
    PMID: 17202453
  5. Measuring disease prevalence: a comparison of musculoskeletal disease using four general practice consultation databases.
    Jordan K, Clarke AM, Symmons DP, Fleming D, Porcheret M, Kadam UT, Croft P.
    Br J Gen Pract. 2007 Jan;57(534):7-14.
    PMID: 17244418
  6. Angiotensin-converting enzyme inhibitor use and protection against pneumonia in patients with diabetes.
    van de Garde EM, Souverein PC, Hak E, Deneer VH, van den Bosch JM, Leufkens HG.
    J Hypertens. 2007 Jan;25(1):235-9.
    PMID: 17143196
  7. Systematic lupus erythematosus prevalence in the UK: methodological issues when using the General Practice Research Database to estimate frequenc y of chronic relapsing-remitting disease.
    Nightingale AL, Farmer RD, de Vries CS. Related Articles, Links
    Pharmacoepidemiol Drug Saf. 2007 Feb;16(2):144-51.
    PMID: 16700093
  8. Use of beta-Blockers and the Risk of Hip/Femur Fracture in the United Kingdom and The Netherlands.
    de Vries F, Souverein PC, Cooper C, Leufkens HG, van Staa TP.
    Calcif Tissue Int. 2007 Feb;80 (2):69-75. Epub 2007 Feb 2.
    PMID: 17308987
  9. Risk of suicide during treatment with venlafaxine, citalopram, fluoxetine, and dothiepin: retrospective cohort study.
    Rubino A, Roskell N, Tennis P, Mines D, Weich S, Andrews E.
    BMJ. 2007 Feb 3;334 (7587):242. Epub 2006 Dec 12.
    PMID: 17164297
  10. Risk of hip fracture in patients with a history of schizophrenia.
    Howard L, Kirkwood G, Leese M.
    Br J Psychiatry. 2007 Feb;190:129-34.
    PMID: 17267929
  11. Relative risk of cardiovascular and cancer mortality in people with severe mental illness from the United Kingdom's General Practice Research Database.
    Osborn DP, Levy G, Nazareth I, Petersen I, Islam A, King MB.
    Arch Gen Psychiatry. 2007 Feb;64(2):242-9. Erratum in: Arch Gen Psychiatry. 2007 Jun;64(6):736.
    PMID: 17283292
  12. Risk of colorectal cancer in women with a prior diagnosis of gynaecologic malignancy.
    Srinivasan R, Yang YX, Rubin SC, Morgan MA, Lewis JD.
    J Clin Gastroenterol. 2007 Mar;41(3):291-6.
    PMID: 17426469
  13. Statins and the risk of pneumonia: a population-based, nested case-control study.
    Schlienger RG, Fedson DS, Jick SS, Jick H, Meier CR.
    Pharmacotherapy. 2007 Mar;27(3):325-32.
    PMID: 17316144
  14. Initial monotherapy with either metformin or sulphonylureas often fails to achieve or maintain current glycaemic goals in patients with Type 2 diabetes in UK primary care.
    Cook MN, Girman CJ, Stein PP, Alexander CM.
    Diabet Med. 2007 Apr;24(4):350-8.
    PMID: 17335466
  15. Vaccinations, infections and antibacterials in the first grass pollen season of life and risk of later hayfever
    Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR, Strachan DP, Cook DG.
    Clin Exp Allergy. 2007 Apr;37(4):512-7.
    PMID: 17430347
  16. Incidence of systemic lupus erythematosus in the United Kingdom
    Somers EC, Thomas SL, Smeeth L, Schoonen WM, Hall AJ., 1990-1999.
    Arthritis Rheum. 2007 Apr 30;57(4):612-618
    PMID: 17471530
  17. Evaluation of the general practice research database congenital heart defects prevalence: Comparison to United Kingdom national systems.
    Wurst KE, Ephross SA, Loehr J, Clark DW, Guess HA.
    Birth Defects Res A Clin Mol Teratol. 2007 Apr;79(4): 309-16.
    PMID: 17286297
  18. Diclofenac and acute myocardial infarction in patients with no major risk factors.
    Jick SS, Kaye JA, Jick H.
    Br J Clin Pharmacol. 2007 May 17; [Epub ahead of print]
    PMID: 17509036
  19. Risk factors and short-term mortality of venous thromboembolism diagnosed in the primary care setting in the United Kingdom.
    Huerta C, Johansson S, Wallander MA, Garcia Rodriguez LA.
    Arch Intern Med. 2007 May 14;167(9):935-43.
    PMID: 17502535
  20. Alarm symptoms in early diagnosis of cancer in primary care: cohort study using General Practice Research Database.
    Jones R, Latinovic R, Charlton J, Gulliford MC.
    BMJ. 2007 May 19;334(7602):1040.
    PMID: 17493982
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  1. Individual fracture risk and the cost-effectiveness of bisphosphonates in patients using oral glucocorticoids.
    van Staa TP, Geusens P, Zhang B, Leufkens HG, Boonen A, Cooper C.
    Rheumatology (Oxford). 2007 Mar;46(3):460-6. Epub 2006 Aug 9.
    PMID: 16899499
  2. Hormone therapy and coronary heart disease in young women.
    Weiner MG, Barnhart K, Xie D, Tannen RL.
    Menopause. 2007 May 11; [Epub ahead of print]
    PMID: 17502840
  3. Lithium use and the risk of fractures.
    Wilting I, de Vries F, Thio BM, Cooper C, Heerdink ER, Leufkens HG, Nolen WA, Egberts AC, van Staa TP
    Bone. 2007 May;40(5):1252-8
    PMID: 17258948
  4. Preferential prescribing of tibolone and combined estrogen plus progestogen therapy in postmenopausal women.
    Velthuis-Te Wierik EJ, Hendricks PT, Martinez C.
    Menopause. 2007 May-Jun;14(3 Pt 1):518-27.
    PMID: 17224856
  5. Prioritizing children's medicines for research: a pharmaco-epidemiological study of antiepileptic drugs.
    Ackers R, Murray ML, Besag FM, Wong IC.
    Br J Clin Pharmacol. 2007 Jun;63(6):689-97. Epub 2007 Jan 25.
    PMID: 17257162
  6. Assessing the burden of influenza and other respiratory infections in England and Wales
    Pitman RJ, Melegaro A, Gelb D, Siddiqui MR, Gay NJ, Edmunds WJ.
    J Infect. 2007 Jun;54(6):530-8.
    PMID: 17097147
  7. Venous thromboembolism and cyproterone acetate in men with prostate cancer: a study using the General Practice Research Database.
    Seaman HE, Langley SE, Farmer RD, de Vries CS.
    BJU Int. 2007 Jun;99(6):1398-403.
    PMID: 17537215
  8. A case-control study of drug risk factors for age-related macular degeneration.
    Douglas IJ, Cook C, Chakravarthy U, Hubbard R, Fletcher AE, Smeeth L.
    Ophthalmology. 2007 Jun;114(6):1164-9.
    PMID: 17544775
  9. Estrogen affects post-menopausal women differently than estrogen plus progestin replacement therapy.
    Tannen RL, Weiner MG, Xie D, Barnhart K.
    Hum Reprod. 2007 Jun;22(6):1769-77.
    PMID: 17347166
  10. The effect of antihypertensive drugs and drug combinations on the incidence of new-onset type-2 diabetes mellitus.
    Burke TA, Sturkenboom MC, Ohman-Strickland PA, Wentworth CE, Rhoads GG.
    Pharmacoepidemiol Drug Saf. 2007 Jul 2; [Epub ahead of print]
    PMID: 17605137
  11. A simulation using data from a primary care practice database closely replicated the women's health initiative trial.
    Tannen RL, Weiner MG, Xie D, Barnhart K.
    J Clin Epidemiol. 2007 Jul;60(7):686-95. Epub 2006 Dec 27.
    PMID: 17573984
  12. The utility of the general practice research database to examine selected congenital heart defects: a validation study.
    Wurst KE, Ephross SA, Loehr J, Clark DW, Guess HA.
    Pharmacoepidemiol Drug Saf. 2007 Aug; 16(8):867-77.
    PMID: 17563909
  13. Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding.
    Delaney JA, Opatrny L, Brophy JM, Suissa S.
    CMAJ 2007 Aug 14; 177(4):347-51.
    PMID: 17698822
  14. The use of antibacterials in children: a report of the Specialist Advisory Committee on Antimicrobial Resistance (SACAR) Paediatric Subgroup.
    Sharland M; SACAR Paediatric Subgroup.
    J Antimicrob Chemother. 2007 Aug; 60 Suppl 1:i15-26.
    PMID: 17656377
  15. Antibacterial prescribing in primary care.
    Petersen I, Hayward AC; SACAR Surveillance Subgroup.
    J Antimicrob Chemother. 2007 Aug; 60 Suppl 1:i43-47.
    PMID: 17656380
  16. Antibacterial prescribing in primary care.
    Petersen I, Hayward AC; SACAR Surveillance Subgroup.
    J Antimicrob Chemother. 2007 Aug; 60 Suppl 1:i43-47.
    PMID: 17656380
  17. Risk for active tuberculosis in inflammatory bowel disease patients.
    Aberra FN, Stettler N, Brensinger C, Lichtenstein GR, Lewis JD.
    Clin Gastroenterol Hepatol. 2007 Sep;5(9):1070-5. Epub 2007 Jul 12.
    PMID: 17627901
  18. Chronic proton pump inhibitor therapy and the risk of colorectal cancer.
    Yang YX, Hennessy S, Propert K, Hwang WT, Sedarat A, Lewis JD.
    Gastroenterology. 2007 Sep;133(3):748-54. Epub 2007 Jun 20.
    PMID: 17678926
  19. Observed association between antidepressant use and pneumonia risk was confounded by comorbidity measures.
    Hennessy S, Bilker WB, Leonard CE, Chittams J, Palumbo CM, Karlawish JH, Yang YX, Lautenbach E, Baine WB, Metlay JP.
    J Clin Epidemiol. 2007 Sep;60(9):911-8. Epub 2007 May 10.
    PMID: 17689807
  20. Clinical features of primary brain tumours: a case-control study using electronic primary care records.
    Hamilton W, Kernick D.
    Br J Gen Pract. 2007 Sep;57(542):695-9.
    PMID: 17761056
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  1. Association between the use of beta-adrenergic receptor agents and the development of venous leg ulcers.
    Margolis DJ, Hoffstad O, Isseroff RR.
    Arch Dermatol. 2007 Oct;143(10):1275-80.
    PMID: 17938341
  2. Unspecified abdominal pain in primary care: the role of gastrointestinal morbidity.
    Wallander MA, Johansson S, Ruigómez A, García Rodríguez LA.
    Int J Clin Pract. 2007 Oct;61(10):1663-70. Epub 2007 Aug 6.
    PMID: 17681003
  3. Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: a population-based cohort study.
    Jackson H, Solaymani-Dodaran M, Card TR, Aithal GP, Logan R, West J.
    Hepatology. 2007 Oct;46(4):1131-7.
    PMID: 17685473
  4. The importance of the disease process and disease-modifying antirheumatic drug treatment in the development of septic arthritis in patients with rheumatoid arthritis.
    Edwards CJ, Cooper C, Fisher D, Field M, van Staa TP, Arden NK.
    Arthritis Rheum. 2007 Oct 15;57(7):1151-7.
    PMID: 17907232
  5. Gout and risk of Parkinson disease: a prospective study.
    Alonso A, Rodríguez LA, Logroscino G, Hernán MA.
    Neurology. 2007 Oct 23;69(17):1696-700.
    PMID: 17954784
  6. Drug treatment discontinuation and achievement of target blood pressure and cholesterol in United Kingdom primary care.
    MacDonald TM, Morant SV, Mozaffari E.
    Curr Med Res Opin. 2007 Nov;23(11):2765-74.
    PMID: 17919356
  7. Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database.
    Petersen I, Johnson AM, Islam A, Duckworth G, Livermore DM, Hayward AC.
    BMJ. 2007 Nov 10;335(7627):982. Epub 2007 Oct 18.
    PMID: 17947744
  8. Migraine and the risk of stroke, TIA, or death in the UK (CME).
    Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
    Headache. 2007 Nov-Dec;47(10):1374-84.
    PMID: 18052947
  9. Incidence of multiple sclerosis in the United Kingdom : Findings from a population-based cohort.
    Alonso A, Jick SS, Olek MJ, Hernán MA.
    J Neurol. 2007 Dec;254(12):1736-41. Epub 2007 Oct 1.
    PMID: 17896096
  10. The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United Kingdom.
    Smitten AL, Choi HK, Hochberg MC, Suissa S, Simon TA, Testa MA, Chan KA.
    Arthritis Rheum. 2007 Dec 15;57(8):1431-8.
    PMID: 18050184
  11. Risk of cerebrovascular accident after a first diagnosis of atrial fibrillation.
    Ruigómez A, García Rodríguez LA, Johansson S, Wallander MA, Edvardsson N.
    Clin Cardiol. 2007 Dec;30(12):624-8.
    PMID: 18069679
  12. Suicide and severe mental illnesses. Cohort study within the UK general practice research database.
    Osborn D, Levy G, Nazareth I, King M.
    Schizophr Res. 2007 Dec 21; [Epub ahead of print]
    PMID: 18155881
  13. Costs and effectiveness of travoprost versus a dorzolamide + timolol fixed combination in first-line treatment of glaucoma: analysis conducted on the United Kingdom General Practitioner Research Database.
    Lafuma A, Berdeaux G.
    Curr Med Res Opin. 2007 Dec;23(12):3009-16.
    PMID: 17958945
  14. The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United Kingdom.
    Smitten AL, Choi HK, Hochberg MC, Suissa S, Simon TA, Testa MA, Chan KA.
    Arthritis Rheum. 2007 Dec 15;57(8):1431-8.
    PMID: 18050184
  15. Lifestyle variables and the risk of myocardial infarction in the General Practice Research Database.
    Delaney JA, Daskalopoulou SS, Brophy JM, Steele RJ, Opatrny L, Suissa S.
    BMC Cardiovasc Disord. 2007 Dec 18;7(1):38 [Epub ahead of print]
    PMID: 18088433
  16. The risk of mortality in patients with psoriasis: results from a population-based study.
    Gelfand JM, Troxel AB, Lewis JD, Kurd SK, Shin DB, Wang X, Margolis DJ, Strom BL.
    Arch Dermatol. 2007 Dec;143(12):1493-9.
    PMID: 18086997
  17. Incidence and risk factors for psoriasis in the general population.
    Huerta C, Rivero E, Rodríguez LA.
    Arch Dermatol. 2007 Dec;143(12):1559-65.
    PMID: 18087008
  18. Upper respiratory tract infection in household contacts of acne patients.
    Bowe WP, Hoffstad O, Margolis DJ.
    Dermatology. 2007;215 (3):213-8.
    PMID: 17823518
  19. Endoscopic findings in a cohort of newly diagnosed gastroesophageal reflux disease patients registered in a UK primary care database.
    Ruigómez A, Rodríguez LA, Wallander MA, Johansson S, Dent J.
    Dis Esophagus. 2007;20(6):504-9.
    PMID: 17958726
  20. Morbidity Associated With Sleep Disorders in Primary Care: A Longitudinal Cohort Study.
    Wallander MA, Johansson S, Ruigómez A, García Rodríguez LA, Jones R.
    Prim Care Companion J Clin Psychiatry. 2007;9(5):338-345.
    PMID: 17998952
  21. Use of a primary care database to determine trends in genital chlamydia testing, diagnostic episodes and management in UK general practice, 1990-2004.
    Hughes G, Williams T, Simms I, Mercer C, Fenton K, Cassell J.
    Sex Transm Infect. 2007 Jul;83(4):310-3. Epub 2007 Mar 14.
    PMID: 17360731
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Research Papers - 2006

  1. Incidence of clinically diagnosed systemic lupus erythematosus 1992-1998 using the UK General Practice Research Database.
    Nightingale AL, Farmer RD, de Vries CS.
    Pharmacoepidemiol Drug Saf. (2006) Jan 3; [Epub ahead of print]
    PMID: 16389657
  2. Hormone replacement therapy and acute myocardial infarction: a large observational study exploring the influence of age.
    Kim J, Evans S, Smeeth L, Pocock S.
    Int J Epidemiol. (2006) Jan 4; [Epub ahead of print]
    PMID: 16394112
  3. Incidence of diagnosed polymyalgia rheumatica and temporal arteritis in the United Kingdom, 1990 to 2001.
    Smeeth L, Cook C, Hall AJ.
    Ann Rheum Dis. (2006) Jan 13; [Epub ahead of print]
    PMID: 16414971
  4. Incidence of common compressive neuropathies in primary care.
    Latinovic R, Gulliford MC, Hughes RA.
    J Neurol Neurosurg Psychiatry. (2006); 77: 263-265
    PMID: 16421136
  5. Glucocorticoid use, other associated factors, and the risk of tuberculosis.
    Jick SS, Lieberman ES, Rahman MU, Choi HK.
    Arthritis Rheum. (2006); 55: 19-26 [Epub ahead of print]
    PMID: 16463407
  6. Risk of schizophrenia in people with coeliac disease, ulcerative colitis and Crohn's disease: a general population-based study.
    West J, Logan RF, Hubbard RB, Card TR.
    Aliment Pharmacol Ther.(2006); 23: 71-4.
    PMID: 16393282
  7. Myocardial infarction risk and hormone replacement: differences between products.
    de Vries CS, Bromley SE, Farmer RD.
    Maturitas. 2006 Feb 20;53(3):343-50. Epub 2005 Jul 22.
    PMID: 16040209
  8. Allergy, histamine 1 receptor blockers, and the risk of multiple sclerosis.
    Alonso A, Jick SS, Hernan MA
    Neurology. (2006) Feb 28; 66: 572-5.
    PMID: 16505314
  9. Risk and predictors of fatigue after infectious mononucleosis in a large primary-care cohort.
    Petersen I, Thomas JM, Hamilton WT, White PD.
    QJM. (2006); 99(1): 49-55. Epub 2005 Dec 5.
    PMID: 16330591
  10. Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database.
    Cassell JA, Mercer CH, Sutcliffe L, Petersen I, Islam A, Brook MG, Ross JD, Kinghorn GR, Simms I, Hughes G, Majeed A, Stephenson JM, Johnson AM, Hayward AC.
    BMJ. (2006) Feb 11; 332: 332-4. Epub 2006 Jan 26.
    PMID: 16439371
  11. Prevalence of inadequate glycemic control among patients with type 2 diabetes in the United Kingdom general practice research database: A series of retrospective analyses of data from 1998 through 2002.
    Fox KM, Gerber Pharmd RA, Bolinder B, Chen J, Kumar S.
    Clin Ther. 2006 Mar;28(3):388-95.
    PMID: 16750453
  12. Simulation of the Syst-Eur randomized control trial using a primary care electronic medical record was feasible.
    Tannen RL, Weiner MG, Marcus SM
    J Clin Epidemiol. (2006) Mar; 59: 254-64.
    PMID: 16488356
  13. Consultations for middle ear disease, antibiotic prescribing and risk factors for reattendance: a case-linked cohort study.
    Williamson I, Benge S, Mullee M, Little P.
    Br J Gen Pract. (2006) Mar; 56: 170-5.
    PMID: 16536956
  14. Upper gastrointestinal complications among users of paracetamol.
    Gonzalez-Perez A, Rodriguez LA
    Basic Clin Pharmacol Toxicol. (2006) Mar; 98: 297-303
    PMID: 16611205
  15. An algorithm to derive a numerical daily dose from unstructured text dosage instructions.
    Shah AD, Martinez C.
    Pharmacoepidemiol Drug Saf. 2006 Mar;15(3):161-6.
    PMID: 16170830
  16. Headache and migraine in primary care: consultation, prescription, and referral rates in a large population.
    Latinovic R, Gulliford M, Ridsdale L.
    J Neurol Neurosurg Psychiatry. 2006 Mar;77(3):385-7.
    PMID: 16484650
  17. All-cause mortality rates in patients with type 1 diabetes mellitus compared with a non-diabetic population from the UK general practice research database, 1992-1999.
    Soedamah-Muthu SS, Fuller JH, Mulnier HE, Raleigh VS, Lawrenson RA, Colhoun HM.
    Diabetologia. (2006) Apr; 49: 660-6. Epub 2006 Jan 24.
    PMID: 16432708
  18. Is there cross-reactivity between penicillins and cephalosporins?
    Apter AJ, Kinman JL, Bilker WB, Herlim M, Margolis DJ, Lautenbach E, Hennessy S, Strom BL
    Am J Med. (2006) Apr; 119: 354.e11-9.
    PMID: 16564780
  19. High risk of cardiovascular disease in patients with type 1 diabetes in the U.K.: a cohort study using the general practice research database.
    Soedamah-Muthu SS, Fuller JH, Mulnier HE, Raleigh VS, Lawrenson RA, Colhoun HM.
    Diabetes Care. (2006) Apr; 29: 798-804.
    PMID: 16567818
  20. Antibiotic Use and Risk of Multiple Sclerosis.
    Alonso A, S Jick S, Jick H, Hernan MA.
    Am J Epidemiol. (2006) Apr 5; [Epub ahead of print]
    PMID: 16597708
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  1. Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease.
    Hernan MA, Logroscino G, Garcia Rodriguez LA.
    Neurology. (2006) Apr 11; 66: 1097-9.
    PMID: 16606925
  2. Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction.
    Andersohn F, Suissa S, Garbe E.
    Circulation. (2006) Apr 25; 113: 1950-7. Epub 2006 Apr 17.
    PMID: 16618816
  3. Chest pain in general practice: incidence, comorbidity and mortality.
    Ruigomez A, Rodriguez LA, Wallander MA, Johansson S, Jones R.
    Fam Pract. (2006) Apr; 23: 167-74. Epub 2006 Feb 3.
    PMID: 16461444
  4. Childhood-Onset Arthritis is Associated with an Elevated Risk of Fracture: A Population-Based Study Using the General Practice Research Database.
    Burnham JM, Shults J, Weinstein R, Lewis JD, Leonard MB.
    Ann Rheum Dis. (2006) Apr 20; [Epub ahead of print]
    PMID: 16627541
  5. Epidemiology and treatment of neuropathic pain: the UK primary care perspective.
    Hall GC, Carroll D, Parry D, McQuay HJ.
    Pain. 2006 May;122(1-2):156-62. Epub 2006 Mar 20.
    PMID: 16545908
  6. Nonsteroidal anti-inflammatory drugs and risk of first hospital admission for heart failure in the general population.
    Huerta C, Varas-Lorenzo C, Castellsague J, Garcia Rodriguez LA.
    Heart. 2006 May 22; [Epub ahead of print]
    PMID: 16717069
  7. Systemic lupus erythematosus prevalence in the U.K.: methodological issues when using the General Practice Research Database to estimate frequency of chronic relapsing-remitting disease.
    Nightingale AL, Farmer RD, de Vries CS.
    Pharmacoepidemiol Drug Saf. 2006 May 15; [Epub ahead of print]
    PMID: 16700093
  8. Acute gastroenteritis is followed by an increased risk of inflammatory bowel disease.
    Garcia Rodriguez LA, Ruigomez A, Panes J.
    Gastroenterology. 2006 May;130(6):1588-94.
    PMID: 16697722
  9. Use of antiepileptic drugs and risk of fractures: case-control study among patients with epilepsy.
    Souverein PC, Webb DJ, Weil JG, Van Staa TP, Egberts AC.
    Neurology. 2006 May 9;66(9):1318-24.
    PMID: 16682661
  10. Hormone replacement therapy and cataract: a population-based case-control study.
    Aina FO, Smeeth L, Hubbard R, Hurt LS, Fletcher AE.
    Eye. 2006 Apr;20(4):417-22.
    PMID: 15846385
  11. Mortality in people with type 2 diabetes in the UK.
    Mulnier HE, Seaman HE, Raleigh VS, Soedamah-Muthu SS, Colhoun HM, Lawrenson RA.
    Diabet Med. 2006 May; 23(5):516-21.
    PMID: 16681560
  12. Bell's palsy and parenteral inactivated influenza vaccine.
    Stowe J, Andrews N, Wise L, Miller E.
    Hum Vaccin. 2006 May-Jun;2(3):110-2. Epub 2006 May 11.
    PMID: 17012908
  13. Statin therapy and reduced risk of pneumonia in patients with diabetes.
    van de Garde EM, Hak E, Souverein PC, Hoes AW, van den Bosch JM, Leufkens HG.
    Thorax. 2006 Jun 29; [Epub ahead of print]
    PMID: 16809409
  14. No association between immunization and Guillain-Barre syndrome in the United Kingdom, 1992 to 2000.
    Hughes RA, Charlton J, Latinovic R, Gulliford MC.
    Arch Intern Med. 2006 Jun 26;166(12):1301-4.
    PMID: 16801513
  15. Discontinuation of antihypertensive drugs among newly diagnosed hypertensive patients in UK general practice.
    Burke TA, Sturkenboom MC, Lu SE, Wentworth CE, Lin Y, Rhoads GG.
    J Hypertens. 2006 Jun;24(6):1193-200.
    PMID: 16685222
  16. Difference in risks of allergic reaction to sulfonamide drugs based on chemical structure.
    Verdel BM, Souverein PC, Egberts AC, Leufkens HG.
    Ann Pharmacother. 2006 Jun;40(6):1040-6. Epub 2006 May 30.
    PMID: 16735666
  17. Risk of aplastic anemia in patients using antiepileptic drugs.
    Handoko KB, Souverein PC, van Staa TP, Meyboom RH, Leufkens HG, Egberts TC, van den Bemt PM.
    Epilepsia. 2006 Jul;47(7):1232-6.
    PMID: 16886988
  18. The impact of dosing frequency on compliance and persistence with bisphosphonates among postmenopausal women in the UK: evidence from three databases.
    Brankin E, Walker M, Lynch N, Aspray T, Lis Y, Cowell W.
    Curr Med Res Opin. 2006 Jul;22(7):1249-56.
    PMID: 16834823
  19. Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study.
    Andersohn F, Schade R, Suissa S, Garbe E.
    Stroke. 2006 Jul;37(7):1725-30. Epub 2006 May 25.
    PMID: 16728684
  20. Incidence of Guillain-Barre syndrome among patients with Campylobacter infection: a general practice research database study.
    Tam CC, Rodrigues LC, Petersen I, Islam A, Hayward A, O'Brien SJ.
    J Infect Dis. 2006 Jul 1;194(1):95-7. Epub 2006 May 26.
    PMID: 16741887
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  1. Diabetes mellitus and antipsychotic treatment in the United Kingdom.
    Carlson C, Hornbuckle K, DeLisle F, Kryzhanovskaya L, Breier A, Cavazzoni P.
    Eur Neuropsychopharmacol. 2006 Jul;16(5):366-75. Epub 2005 Dec 13.
    PMID: 16356695
  2. Reducing variation in antibacterial prescribing rates for 'cough/cold' and sore throat between 1993 and 2001: regional analyses using the general practice research database.
    Smith S, Smith GE, Heatlie H, Bashford JN, Ashcroft DM, Verlander NQ, Duckworth GJ, Mason B, Smyth B, Maxwell S.
    Public Health. 2006 Aug;120(8):752-9. Epub 2006 Jul 7.
    PMID: 16828131
  3. Epidemiology, prescribing patterns and resource use associated with overactive bladder in UK primary care.
    Odeyemi IA, Dakin HA, O'Donnell RA, Warner J, Jacobs A, Dasgupta P.
    Int J Clin Pract. 2006 Aug;60(8):949-58.
    PMID: 16893437
  4. Safety of medications prescribed before and during early pregnancy in a cohort of 81,975 mothers from the UK General Practice Research Database.
    Hardy JR, Leaderer BP, Holford TR, Hall GC, Bracken MB.
    Pharmacoepidemiol Drug Saf. 2006 Aug;15(8):555-64.
    PMID: 16767799
  5. Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications.
    Hernandez-Diaz S, Garcia Rodriguez LA.
    BMC Med. 2006 Sep 20;4(1):22 [Epub ahead of print]
    PMID: 16987411
  6. Comparison of gastro-oesophageal reflux disease and heartburn diagnoses in UK primary care.
    Ruigomez A, Garcia Rodriguez LA, Wallander MA, Johansson S, Dent J.
    Curr Med Res Opin. 2006 Sep;22(9):1661-8.
    PMID: 16968569
  7. The impact of over-the-counter simvastatin on the number of statin prescriptions in the United Kingdom: a view from the General Practice Research Database.
    Filion KB, Chris Delaney JA, Brophy JM, Ernst P, Suissa S.
    Pharmacoepidemiol Drug Saf. 2006 Sep 5; [Epub ahead of print]
    PMID: 16953516
  8. Physical and psychological co-morbidity in irritable bowel syndrome: a matched cohort study using the General Practice Research Database.
    Jones R, Latinovic R, Charlton J, Gulliford M.
    Aliment Pharmacol Ther. 2006 Sep 1;24(5):879-86.
    PMID: 16918893
  9. Is an internal comparison better than using national data when estimating mortality in longitudinal studies?
    Card TR, Solaymani-Dodaran M, Hubbard R, Logan RF, West J.
    J Epidemiol Community Health. 2006 Sep;60(9):819-21.
    PMID: 16905729
  10. Pneumococcal polysaccharide vaccine uptake in England, 1989-2003, prior to the introduction of a vaccination programme for older adults.
    Noakes K, Pebody RG, Gungabissoon U, Stowe J, Miller E. J Public Health (Oxf). 2006 Sep;28(3):242-7. Epub 2006 Jul 4.
    PMID: 16820432
  11. Hormone therapy and cerebrovascular events: a population-based nested case-control study.
    Arana A, Varas C, Gonzalez-Perez A, Gutierrez L, Bjerrum L, Garcia Rodriguez LA.
    Menopause. 2006 Sep-Oct;13(5):730-6.
    PMID: 16946686
  12. Nonsteroidal antiinflammatory drugs and acute myocardial infarction in patients with no major risk factors.
    Jick H, Kaye JA, Russmann S, Jick SS.
    Pharmacotherapy. 2006 Oct;26(10):1379-87.
    PMID: 16999647
  13. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis.
    van Staa TP, Geusens P, Bijlsma JW, Leufkens HG, Cooper C.
    Arthritis Rheum. 2006 Oct;54(10):3104-12.
    PMID: 17009229
  14. Risk of myocardial infarction in patients with psoriasis.
    Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB.
    JAMA. 2006 Oct 11;296(14):1735-41.
    PMID: 17032986
  15. Reanalysis of two studies with contrasting results on the association between statin use and fracture risk: the General Practice Research Database.
    de Vries F, de Vries C, Cooper C, Leufkens B, van Staa TP.
    Int J Epidemiol. 2006 Oct;35(5):1301-8.
    PMID: 17053011
  16. The risk of lymphoma in patients with psoriasis.
    Gelfand JM, Shin DB, Neimann AL, Wang X, Margolis DJ, Troxel AB.
    J Invest Dermatol. 2006 Oct;126(10):2194-201. Epub 2006 Jun 1.
    PMID: 16741509
  17. Age-related changes in consultations and antibiotic prescribing for acute respiratory infections, 1995-2000. Data from the UK General Practice Research Database.
    Ashworth M, Charlton J, Latinovic R, Gulliford M.
    J Clin Pharm Ther. 2006 Oct;31(5):461-7.
    PMID: 16958824
  18. Fracture risk in people with primary biliary cirrhosis: a population-based cohort study.
    Solaymani-Dodaran M, Card TR, Aithal GP, West J.
    Gastroenterology. 2006 Dec;131(6):1752-7. Epub 2006 Sep 8.
    PMID: 17087953
  19. Prevalence of contraindicated medical conditions and use of precluded medications in patients with painful neuropathic disorders prescribed amitriptyline.
    Gore M, Dukes E, Rowbotham D, Tai KS, Leslie DL.
    Pain Pract. 2006 Dec;6(4):265-72. PMID: 17129307
  20. Incidence and risk factors for herpes zoster among patients with inflammatory bowel disease.
    Gupta G, Lautenbach E, Lewis JD.
    Clin Gastroenterol Hepatol. 2006 Dec;4(12):1483-90.
    PMID: 17162240
  21. Esophageal stricture: incidence, treatment patterns, and recurrence rate.
    Ruigomez A, Garcia Rodriguez LA, Wallander MA, Johansson S, Eklund S.
    Am J Gastroenterol. 2006 Dec; 101 (12) : 2685-92.
    PMID: 17227515
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Research Papers 2005

  1. Increased Utilization of Primary Care 5 Years Before Diagnosis of Type 2 Diabetes: A matched cohort study.
    Gulliford MC, Charlton J, Latinovic R.
    Diabetes Care. (2005) Jan; 28(1): 47-52.
    PMID: 15616232
  2. Antidiabetic drugs and heart failure risk in patients with type 2 diabetes in the u.k. Primary care setting.
    Maru S, Koch GG, Stender M, Clark D, Gibowski L, Petri H, White AD, Simpson RJ Jr.
    Diabetes Care. (2005) Jan; 28(1): 20-6.
    PMID: 15616228
  3. Breast cancer risk among users of antidepressant medications.
    Gonzalez-Perez A, Garcia Rodriguez LA.
    Epidemiology. (2005) Jan; 16(1): 101-5.
    PMID: 15613952
  4. Incidence of fractures among epilepsy patients: a population-based retrospective cohort study in the General Practice Research Database.
    Souverein PC, Webb DJ, Petri H, Weil J, Van Staa TP, Egberts T.
    Epilepsia. (2005) Feb;46(2):304-10.
    PMID: 15679512
  5. Autoimmune cholestatic liver disease in people with coeliac disease: a population-based study of their association.
    Lawson A, West J, Aithal GP, Logan RF.
    Aliment Pharmacol Ther. (2005) Feb 15;21(4):401-5.
    PMID: 15709990
  6. Time trends in eating disorder incidence.
    Currin L, Schmidt U, Treasure J, Jick H.
    Br J Psychiatry. (2005) Feb;186:132-5.
    PMID: 15684236
  7. Trends in antihypertensive and lipid-lowering therapy in subjects with type II diabetes: clinical effectiveness or clinical discretion?
    Gulliford MC, Charlton J, Latinovic R.
    J Hum Hypertens. (2005) Feb; 19(2): 111-7.
    PMID: 15361893
  8. Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study.
    Martinez C, Rietbrock S, Wise L, Ashby B, Chick J, Moseley J, Evans S, Gunnell D.
    BMJ (2005), Feb 19;330(7488):389
    PMID: 15718538
  9. No risk of drug-associated liver injury with alpha(1)-adrenoreceptor blocking agents in men with BPH: results from an observational study using the GPRD.
    Clifford GM, Logie J, Farmer RD.
    Pharmacoepidemiol Drug Saf. (2005) Feb;14(2):75-80
    PMID: 15386708
  10. Gout epidemiology: results from the UK General Practice Research Database, 1990-1999.
    Mikuls TR, Farrar JT, Bilker WB, Fernandes S, Schumacher HR Jr, Saag KG.
    Ann Rheum Dis. (2005) Feb; 64(2):267-72
    PMID: 15647434
  11. Nonsteroidal anti-inflammatory drugs and risk of ARF in the general population.
    Huerta C, Castellsague J, Varas-Lorenzo C, Garcia Rodriguez LA.
    Am J Kidney Dis. (2005) Mar;45(3):531-9.
    PMID: 15754275
  12. A simple score for estimating the long-term risk of fracture in patients using
    oral glucocorticoids. van Staa TP, Geusens P, Pols HA, de Laet C, Leufkens HG, Cooper C.
    QJM. (2005) Mar;98(3):191-8.
    PMID: 15728400
  13. Tamoxifen-treated breast carcinoma patients and the risk of acute myocardial infarction and newly-diagnosed angina.
    Bradbury BD, Lash TL, Kaye JA, Jick SS.
    Cancer. (2005) Mar 15;103(6):1114-21.
    PMID: 15712362
  14. Incidence and outcome of persons with a clinical diagnosis of heart failure in a general practice population of 696,884 in the United Kingdom.
    de Giuli F, Khaw KT, Cowie MR, Sutton GC, Ferrari R, Poole-Wilson PA.
    Eur J Heart Fail. (2005) Mar 16;7(3):295-302.
    PMID: 15718168
  15. Intraclass correlation coefficient and outcome prevalence are associated in clustered binary data.
    Gulliford MC, Adams G, Ukoumunne OC, Latinovic R, Chinn S, Campbell MJ.
    J Clin Epidemiol. (2005) Mar;58(3):246-51.
    PMID: 15718113
  16. Incidence, prevalence and management of lower urinary tract symptoms in men in the UK.
    Logie J, Clifford GM, Farmer RD.
    BJU Int. (2005) Mar;95(4):557-62.
    PMID: 15705080
  17. Does lithium therapy protect against the onset of dementia?
    Dunn N, Holmes C, Mullee M.
    Alzheimer Dis Assoc Disord. (2005) Jan-Mar;19(1):20-2.
    PMID: 15764867
  18. A probabilistic cost-effectiveness analysis of escitalopram, generic citalopram and venlafaxine as a first-line treatment of major depressive disorder in the UK.
    Wade AG, Toumi I, Hemels ME.
    Curr Med Res Opin. (2005) Apr;21(4):631-42.
    PMID: 15899113
  19. Use of antibiotics and risk of breast cancer.
    Garcia Rodriguez LA, Gonzalez-Perez A.
    Am J Epidemiol. (2005) Apr 1;161(7):616-9.
    PMID: 15781950
  20. General population based study of the impact of tricyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction.
    Tata LJ, West J, Smith C, Farrington P, Card T, Smeeth L, Hubbard R.
    Heart. (2005) Apr;91(4):465-71.
    PMID: 15772201
Back to top
  1. Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction.
    Fischer LM, Schlienger RG, Matter CM, Jick H, Meier CR.
    Pharmacotherapy. (2005) Apr;25(4):503-10.
    PMID: 15977911
  2. Association between dementia and infectious disease: evidence from a case-control study.
    Dunn N, Mullee M, Perry VH, Holmes C.
    Alzheimer Dis Assoc Disord. (2005) Apr-Jun;19(2):91-4.
    PMID: 15942327
  3. Severity of obstructive airway disease and risk of osteoporotic fracture.
    de Vries F, van Staa TP, Bracke MS, Cooper C, Leufkens HG, Lammers JW.
    Eur Respir J. (2005) May;25(5):879-84.
    PMID: 15863646
  4. Glycemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes.
    Cook MN, Girman CJ, Stein PP, Alexander CM, Holman RR.
    Diabetes Care. (2005) May;28(5):995-1000.
    PMID: 15855556
  5. Hormone replacement therapy and cataract: a population-based case-control study.
    Aina FO, Smeeth L, Hubbard R, Hurt LS, Fletcher AE.
    Eye. (2006) May;20:417-22. Epub 2005 Apr 22.
    PMID: 15846385
  6. Respiratory medications and the risk of cardiac arrhythmias.
    Huerta C, Lanes SF, Garcia Rodriguez LA.
    Epidemiology. (2005) May;16(3):360-6.
    PMID: 15824553
  7. Antibiotic use and the risk of flare of inflammatory bowel disease.
    Aberra FN, Brensinger CM, Bilker WB, Lichtenstein GR, Lewis JD.
    Clin Gastroenterol Hepatol. (2005) May;3(5):459-65.
    PMID: 15880315
  8. Antibiotic prescribing in general practice and hospital admissions for peritonsillar abscess, mastoiditis, and rheumatic fever in children: time trend analysis.
    Sharland M, Kendal H, Yeates D, Randall A, Hughes G, Glasziou P, Mant D.
    BMJ. (2005); 331: 328-9. Epub 2005 Jun 20.
    PMID: 15967760
  9. Concerning: 'Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database'.
    Fleming DM, Ross AM, Cross KW, Kendall H, Elliot AJ.
    J Public Health (Oxf). (2005) Jun;27(2):228-9. Epub 2005 Mar 4.
    PMID: 15749719
  10. Obtaining optimal control in mild asthma: theory and practice.
    Watson L, Kerstjens HA, Rabe KF, Kiri V, Visick GT, Postma DS.
    Fam Pract. (2005) Jun;22(3):305-10. Epub 2005 Apr 1.
    PMID: 15805133
  11. Prevalence of risk factors for suicide in patients prescribed venlafaxine, fluoxetine, and citalopram.
    Mines D, Hill D, Yu H, Novelli L.
    Pharmacoepidemiol Drug Saf. (2005) Jun;14(6):367-72.
    PMID: 15883980
  12. Cigarette smoking and the progression of multiple sclerosis.
    Hernan MA, Jick SS, Logroscino G, Olek MJ, Ascherio A, Jick H.
    Brain. (2005) Jun;128(Pt 6):1461-5. Epub 2005 Mar 9.
    PMID: 15758034
  13. Type 2 diabetes mellitus and the risk of colorectal cancer.
    Yang YX, Hennessy S, Lewis JD.
    Clin Gastroenterol Hepatol. (2005) Jun;3(6):587-94.
    PMID: 15952101
  14. 5-aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study.
    van Staa TP, Card TR, Leufkens HG, Logan RF.
    Gut. 2005 Nov;54(11):1573-8. Epub 2005 Jun 30
    PMID: 15994215
  15. Utility of routinely acquired primary care data for paediatric disease epidemiology and pharmacoepidemiology.
    Helms PJ, Ekins Daukes S, Taylor MW, Simpson CR, McLay JS.
    Br J Clin Pharmacol. (2005) Jun;59(6):684-90.
    PMID: 15948933
  16. Predictors and prognosis of paroxysmal atrial fibrillation in general practice in the UK.
    Ruigomez A, Johansson S, Wallander MA, Garcia Rodriguez LA.
    BMC Cardiovasc Disord. (2005) Jul 11;5(1):20.
    PMID: 16030083
  17. Case-mix and variation in specialist referrals in general practice.
    Sullivan CO, Omar RZ, Ambler G, Majeed A.
    Br J Gen Pract. (2005) Jul;55(516):529-33.
    PMID: 16004738
  18. Gastroesophageal reflux disease and asthma: a longitudinal study in UK general practice.
    Ruigomez A, Rodriguez LA, Wallander MA, Johansson S, Thomas M, Price D.
    Chest. (2005) Jul;128(1):85-93.
    PMID: 16002920
  19. Cesarean delivery in the United Kingdom: time trends in the general practice research database.
    Black C, Kaye JA, Jick H.
    Obstet Gynecol. (2005) Jul;106(1):151-5.
    PMID: 15994631
  20. Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database.
    Russmann S, Kaye JA, Jick SS, Jick H.
    Br J Clin Pharmacol. (2005) Jul;60(1):76-82.
    PMID: 15963097
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  1. The relationship between time since registration and measured incidence rates in the General Practice Research Database.
    Lewis JD, Bilker WB, Weinstein RB, Strom BL.
    Pharmacoepidemiol Drug Saf. (2005) Jul;14(7):443-51.
    PMID: 15898131
  2. Suboptimal physician adherence to quality indicators for the management of gout and asymptomatic hyperuricaemia: results from the UK General Practice Research Database (GPRD).
    Mikuls TR, Farrar JT, Bilker WB, Fernandes S, Saag KG.
    Rheumatology (Oxford). (2005) Aug;44(8):1038-42. Epub 2005 May 3.
    PMID: 15870145
  3. The prognosis of different fatigue diagnostic labels: a longitudinal survey.
    Hamilton WT, Gallagher AM, Thomas JM, White PD.
    Fam Pract. (2005) Aug;22(4):383-8. Epub 2005 Apr 1.
    PMID: 15805126
  4. Cholecystectomy and the risk of colorectal cancer.
    Shao T, Yang YX.
    Am J Gastroenterol. (2005) Aug;100(8):1813-20.
    PMID: 16086719
  5. Inhaled corticosteroids in chronic obstructive pulmonary disease: results from two observational designs free of immortal time bias.
    Kiri VA, Pride NB, Soriano JB, Vestbo J.
    Am J Respir Crit Care Med. (2005) Aug 15;172(4):460-4. Epub 2005 May 18.
    PMID: 15901610
  6. New cases of diabetes mellitus in England and Wales, 1994-1998: Database study.
    Ryan R, Newnham A, Khunti K, Majeed A.
    Public Health. (2005); 119: 892-9. Epub 2005 Aug 2.
    PMID: 16083928
  7. Obesity and the risk of prostate cancer (United States).
    Bradbury BD, Wilk JB, Kaye JA.
    Cancer Causes Control. (2005) Aug;16(6):637-41.
    PMID: 16049801
  8. An algorithm to derive a numerical daily dose from unstructured text dosage instructions.
    Shah AD, Martinez C.
    Pharmacoepidemiol Drug Saf. (2005) Sep 19; [Epub ahead of print]
  9. Inhaled corticosteroids are more effective in COPD patients when used with LABA than with SABA.
    Kiri VA, Bettoncelli G, Testi R, Viegi G.
    Respir Med. (2005) Sep;99(9):1115-24. Epub 2005 Mar 21.
    PMID: 15921904
  10. Antidiabetic therapy and the risk of heart failure in type 2 diabetic patients: an independent effect or confounding by indication.
    Koro CE, Bowlin SJ, Weiss SR.
    Pharmacoepidemiol Drug Saf. (2005); Oct;14(10):697-703.
    PMID: 15654719
  11. Influenza vaccine uptake and distribution in England and Wales using data from the General Practice Research Database, 1989/90-2003/04.
    Joseph C, Goddard N, Gelb D
    J Public Health (Oxf). (2005) ; 27: 371-7. Epub 2005 Oct 5
    PMID: 16207735
  12. The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from the United Kingdom General Practice Research Database.
    Edwards CJ, Arden NK, Fisher D, Saperia JC, Reading I, Van Staa TP, Cooper C.
    Rheumatology (Oxford). 2005 Nov;44(11):1394-8. Epub 2005 Jul 19
    PMID: 16030083
  13. Diabetes mellitus and antipsychotic treatment in the United Kingdom.
    Carlson C, hornbuckle K, Delisle F, Kryzhanovskaya L, breier A, Cavazzoni P.
    Eur Neuropsychopharmacol. (2005) Dec 12; [Epub ahead of print]
    PMID: 16356695
  14. Risk of hip/femur fractures in patients using antipsychotics.
    Hugenholtz GW, Heerdink ER, van Staa TP, Nolen WA, Egberts AC.
    Bone. (2005) Dec; 37: 864-70. Epub 2005 Aug 19
    PMID: 16111927
  15. Drug interactions and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation treated with warfarin.
    Gasse C, Hollowell J, Meier CR, Haefeli WE.
    Thromb Haemost. (2005); 94: 537-43.
    PMID: 16268469
  16. Prostate cancer risk among men with diabetes mellitus (Spain).
    Gonzalez-Perez A, Garcia Rodriguez LA.
    Cancer Causes Control. (2005); 16: 1055-8.
    PMID: 16184470
  17. Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease.
    Dial S, Delaney JA, Barkun AN, Suissa S.
    JAMA. (2005); 294: 2989-95.
    PMID: 16414946
  18. Mortality associated with Barrett's esophagus and gastroesophageal reflux disease diagnoses-a population-based cohort study.
    Solaymani-Dodaran M, Logan RF, West J, Card T.
    Am J Gastroenterol. (2005); 100: 2616-21.
    PMID: 16393209
  19. Prevalence and treatment of psoriasis in the United Kingdom: a population-based study.
    Gelfand JM, Weinstein R, Porter SB, Neimann AL, Berlin JA, Margolis DJ.
    Arch Dermatol. (2005); 141: 1537-41.
    PMID: 16365254
  20. Substance misuse and psychiatric illness: prospective observational study using the general practice research database.
    Frisher M, Crome I, Macleod J, Millson D, Croft P.
    J Epidemiol Community Health. (2005); 59: 847-50.
    PMID: 16166357
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  1. Recent use of oral contraceptives and the risk of multiple sclerosis.
    Alonso A, Jick SS, Olek MJ, Ascherio A, Jick H, Hernan MA
    Arch Neurol. (2005); 62: 1362-5.
    PMID: 16157743
  2. Increased risk for demyelinating diseases in patients with inflammatory bowel disease.
    Gupta G, Gelfand JM, Lewis JD.
    Gastroenterology. (2005); 129: 819-26.
    PMID: 16143121
  3. Antibiotics and the risk of breast cancer.
    Kaye JA, Jick H.
    Epidemiology. (2005); 16: 688-90.
    PMID: 16135947
  4. A case control study of age related macular degeneration and use of statins.
    Smeeth L, Cook C, Chakravarthy U, Hubbard R, Fletcher AE.
    Br J Ophthalmol. (2005); 89: 1171-5.
    PMID: 16113375
  5. Patterns of Comorbidities in Newly Diagnosed COPD and Asthma in Primary Care.
    Soriano JB, Visick GT, Muellero va H, Payvandi N, Hansell AL.
    Chest. (2005); 128:2099-107.
    PMID: 16236861
  6. Antibiotic treatment of acne may be associated with upper respiratory tract infections.
    Margolis DJ, Bowe WP, Hoffstad O, Berlin JA.
    Arch Dermatol. (2005); 141: 1132-6
    PMID: 16172310
  7. Variations in antibiotic prescribing and consultation rates for acute respiratory infection in UK general practices 1995-2000.
    Ashworth M, Charlton J, Ballard K, Latinovic R, Gulliford M.
    Br J Gen Pract.(2005); 55: 603-8
    PMID: 16105368
  8. Tibolone and endometrial cancer: a cohort and nested case-control study in the UK.
    de Vries CS, Bromley SE, Thomas H, Farmer RD.
    Drug Saf. (2005);28(3):241-9
    PMID: 15733028
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Research Papers 2004

  1. A population-based study of the incidence, cause, and severity of anaphylaxis in the United Kingdom.
    Peng MM, Jick H.
    Arch Intern Med. (2004) Feb 9; 164(3):317-9.
    PMID: 14769628
  2. Developing a large electronic primary care database (Doctors' Independent Network) for research.
    Carey IM, Cook DG, De Wilde S, Bremner SA, Richards N, Caine S, Strachan DP, Hilton SR.
    Int J Med Inform. (2004) Jun 15; 73(5): 443-53.
    PMID: 15171985
  3. Risk of extra-oesophageal malignancies and colorectal cancer in Barrett's oesophagus and gastro-oesophageal reflux.
    Solaymani-Dodaran M, Logan RF, West J, Card T, Coupland C.
    Scand J Gastroenterol. (2004) Jul; 39(7): 680-5.
    PMID: 15370691
  4. Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case-control study.
    Souverein PC, Berard A, Van Staa TP, Cooper C, Egberts AC, Leufkens HG, Walker BR.
    Heart. (2004) Aug; 90(8): 859-65.
    PMID: 15253953
  5. Breast cancer incidence and use of antihypertensive medication in women.
    Gonzalez-Perez A, Ronquist G, Garcia Rodriguez LA.
    Pharmacoepidemiol Drug Saf. (2004) Aug; 13(8): 581-5.
    PMID: 15317040
  6. A comparison of the recording of 30 common childhood conditions in the Doctor's Independent Network and General Practice Research Databases.
    De Wilde S, Carey IM, Bremner SA, Richards N, Hilton SR, Strachan DP, Cook DG.
    Health Stat Q. 2004 Summer;(22):21-31.
    PMID: 15704391
  7. Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database.
    Ashworth M, Latinovic R, Charlton J, Cox K, Rowlands G, Gulliford M.
    J Public Health (Oxf).(2004) Sep; 26(3): 268-74.
    PMID: 15454595
  8. Tamoxifen and cataracts: a null association.
    Bradbury BD, Lash TL, Kaye JA, Jick SS.
    Breast Cancer Res Treat. (2004) Sep; 87(2): 189-96.
    PMID: 15377843
  9. Use of beta-blockers and risk of fractures.
    Schlienger RG, Kraenzlin ME, Jick SS, Meier CR.
    JAMA.(2004) Sep 15; 292(11): 1326-32.
    PMID: 15367554
  10. Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study.
    Hernan MA, Jick SS, Olek MJ, Jick H.
    Neurology. (2004) Sep 14; 63(5): 838-42.
    PMID: 15365133
  11. MMR vaccination and pervasive developmental disorders: a case-control study.
    Smeeth L, Cook C, Fombonne E, Heavey L, Rodrigues LC, Smith PG, Hall AJ.
    Lancet. (2004) Sep 11; 364(9438): 963-9.
    PMID: 15364187
  12. Epidemiology of restless legs syndrome as diagnosed in UK primary care.
    Van De Vijver DA, Walley T, Petri H.
    Sleep Med. (2004) Sep; 5(5): 435-40.
    PMID: 15341887
  13. Malignancy and mortality in people with coeliac disease: population based cohort study.
    West J, Logan RF, Smith CJ, Hubbard RB, Card TR.
    BMJ. (2004) Sep 25; 329(7468): 716-9. Epub 2004 Jul 21.
    PMID: 15269095
  14. Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol.
    Hennessy S, Bilker WB, Knauss JS, Kimmel SE, Margolis DJ, Morrison MF, Reynolds RF, Glasser DB, Strom BL
    Br J Clin Pharmacol. (2004); 58: 81-7. Erratum in: Br J Clin Pharmacol. (2004) Aug; 58(2):228.
    PMID: 15206997
  15. Natural history of gastro-oesophageal reflux disease diagnosed in general practice.
    Ruigomez A, Garcia Rodriguez LA, Wallander MA, Johansson S, Graffner H, Dent J.
    Aliment Pharmacol Ther. (2004) Oct 1; 20(7): 751-60.
    PMID: 15379835
  16. A prospective study of alcoholism and the risk of Parkinson's disease.
    Hernan MA, Logroscino G, Rodriguez LA.
    J Neurol. (2004) Oct; 251 Suppl 7: vII14-7.
    PMID: 15505749
  17. Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients.
    Yang YX, Hennessy S, Lewis JD.
    Gastroenterology. (2004) Oct; 127(4): 1044-50.
    PMID: 15480982
  18. Are inhaled corticosteroids associated with an increased risk of fracture in children?
    van Staa TP, Bishop N, Leufkens HG, Cooper C.
    Osteoporos Int. 2004 Oct;15(10):785-91. Epub 2004 Feb 21.
    PMID: 14985948
  19. Rate of first recorded diagnosis of autism and other pervasive developmental disorders in United Kingdom general practice, 1988 to 2001.
    Smeeth L, Cook C, Fombonne PE, Heavey L, Rodrigues LC, Smith PG, Hall AJ.
    BMC Med. (2004) Nov 09; 2(1): 39.
    PMID: 15535890
  20. Persistency and treatment failure in newly diagnosed open angle glaucoma patients in the United Kingdom.
    Zhou Z, Althin R, Sforzolini BS, Dhawan R.
    Br J Ophthalmol. (2004) Nov; 88(11): 1391-4.
    PMID: 15489479
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  1. Strategies for identifying pregnancies in the automated medical records of the General Practice Research Database.
    Hardy JR, Holford TR, Hall GC, Bracken MB.
    Pharmacoepidemiol Drug Saf. (2004) Nov; 13(11): 749-59.
    PMID: 15386720
  2. The psychosocial outcome of pregnancy in women with psychotic disorders.
    Howard LM, Goss C, Leese M, Appleby L, Thornicroft G.
    Schizophr Res. (2004) Nov 1; 71(1): 49-60.
    PMID: 15374572
  3. Risk of myocardial infarction and stroke after acute infection or vaccination.
    Smeeth L, Thomas SL, Hall AJ, Hubbard R, Farrington P, Vallance P.
    N Engl J Med. (2004) Dec 16; 351(25): 2611-8.
    PMID: 15602021
  4. What has happened to antimicrobial usage in primary care in the United Kingdom since the SMAC report? - Description of trends in antimicrobial usage using the General Practice Research Database.
    Smith GE, Smith S, Heatlie H, Bashford JN, Hawker J, Ashcroft D, Millson D, Verlander NQ, Warren R.
    J Public Health (Oxf). (2004) Dec; 26(4): 359-64.
    PMID: 15598854
  5. Discontinuation of nonsteroidal anti-inflammatory drug therapy and risk of acute myocardial infarction.
    Fischer LM, Schlienger RG, Matter CM, Jick H, Meier CR.
    Arch Intern Med. (2004) Dec 13-27; 164(22): 2472-6.
    PMID: 15596638
  6. Epidemiology of lower limb fractures in general practice in the United Kingdom.
    Kaye JA, Jick H.
    Inj Prev. (2004) Dec; 10(6): 368-74.
    PMID: 15583259
  7. Incidence of fatigue symptoms and diagnoses presenting in UK primary care from 1990 to 2001.
    Gallagher AM, Thomas JM, Hamilton WT, White PD.
    J R Soc Med. (2004) Dec; 97(12): 571-5.
    PMID: 15574853
  8. The epidemiology of the comorbidity of epilepsy in the general population.
    Gaitatzis A, Carroll K, Majeed A, W Sander J.
    Epilepsia. (2004) Dec;45(12):1613-22.
    PMID: 15571520
  9. A drug utilisation study of antidepressants in children and adolescents using the General Practice Research Database.
    Murray ML, de Vries CS, Wong IC. Arch Dis Child. (2004) Dec; 89(12): 1098-102.
    PMID: 15557040
  10. Prevalence of comorbid psychiatric illness and substance misuse in primary care in England and Wales.
    Frisher M, Collins J, Millson D, Crome I, Croft P.
    J Epidemiol Community Health. (2004) Dec; 58(12): 1036-41.
    PMID: 15547069
  11. Epidemiology of childhood fractures in Britain: a study using the general practice research database.
    Cooper C, Dennison EM, Leufkens HG, Bishop N, van Staa TP.
    J Bone Miner Res. (2004) Dec; 19(12): 1976-81. Epub 2004 Sep 20.
    PMID: 15537440
  12. Seasonal variation in flares of inflammatory bowel disease.
    Lewis JD, Aberra FN, Lichtenstein GR, Bilker WB, Brensinger C, Strom BL.
    Gastroenterology. (2004); 126: 665-73.
    PMID: 14988820
  13. Triptans in migraine: The risks of stroke, cardiovascular disease, and death in practice.
    Hall GC, Brown MM, Mo J, MacRae KD.
    Neurology. (2004); 62: 563-8.
    PMID: 14981171
  14. The risk of severe depression, psychosis or panic attacks with prophylactic antimalarials.
    Meier CR, Wilcock K, Jick SS.
    Drug Saf. (2004); 27: 203-13.
    PMID: 14756582
  15. Statin use and cancer risk in the General Practice Research Database.
    Kaye JA, Jick H
    Br J Cancer. (2004); 90: 635-7.
    PMID: 14760377
  16. Hip fractures in patients with inflammatory bowel disease and their relationship to corticosteroid use: a population based cohort study.
    Card T, West J, Hubbard R, Logan RF.
    Gut. (2004); 53: 251-5.
    PMID: 14724159
  17. Antibiotic use and the development of Crohn's disease.
    Card T, Logan RF, Rodrigues LC, Wheeler JG.
    Gut. (2004); 53: 246-50.
    PMID: 14724158
  18. Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarction.
    Fischer LM, Schlienger RG, Matter C, Jick H, Meier CR.
    Am J Cardiol. (2004); 93: 198-200.
    PMID: 14715346
  19. Association between captopril, other antihypertensive drugs and risk of prostate cancer.
    Ronquist G, Rodriguez LA, Ruigomez A, Johansson S, Wallander MA, Frithz G, Svardsudd K.
    Prostate. (2004); 58: 50-6.
    PMID: 14673952
  20. A cohort study of the effectiveness of influenza vaccine in older people, performed using the United kingdom general practice research database.
    Mangtani P, Cumberland P, Hodgson CR, Roberts JA, Cutts FT, Hall AJ.
    J Infect Dis. (2004); 190: 1-10
    PMID: 15195237
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  1. Incidence and prevalence of drug-treated attention deficit disorder among boys in the UK.
    Jick H, Kaye JA, Black C.
    Br J Gen Pract. (2004); 54: 345-7
    PMID: 15113516
  2. Validation of the diagnosis of autism in general practitioner records.
    Fombonne E, Heavey L, Smeeth L, Rodrigues LC, Cook C, Smith PG, Meng L, Hall AJ.
    BMC Public Health. (2004); 4: 5
    PMID: 15113435
  3. Represcription of penicillin after allergic-like events.
    Apter AJ, Kinman JL, Bilker WB, Herlim M, Margolis DJ, Lautenbach E, Hennessy S, Strom BL.
    J Allergy Clin Immunol. (2004); 113: 764-70
    PMID: 15100685
  4. 5-Alpha reductase inhibition provides superior benefits to alpha blockade by preventing AUR and BPH-related surgery.
    Boyle P, Roehrborn C, Harkaway R, Logie J, de la Rosette J, Emberton M.
    Eur Urol. (2004); 45: 620-6
    PMID: 15082205
  5. Late-onset seizures as a predictor of subsequent stroke.
    Cleary P, Shorvon S, Tallis R.
    Lancet. (2004); 363: 1184-6
    PMID: 15081649
  6. Inverse association between nonsteroidal anti-inflammatory drugs and prostate cancer.
    Garcia Rodriguez LA, Gonzalez-Perez A.
    Cancer Epidemiol Biomarkers Prev. (2004); 13: 649-53
    PMID: 15066932
  7. Utilisation of hormone replacement therapy in the United Kingdom. A descriptive study using the general practice research database.
    Bromley SE, de Vries CS, Farmer RD.
    BJOG. (2004); 111: 369-76
    PMID: 15008775
  8. Medical conditions associated with venous leg ulcers.
    Margolis DJ, Knauss J, Bilker W.
    Br J Dermatol. (2004); 150: 267-73
    PMID: 14996097
  9. Pharmaceutical treatment of symptomatic vertebral fractures in primary care.
    Torgerson DJ, Sykes D, Puffer S, Brown P, Cooper C.
    Ann Rheum Dis. (2004); 63: 853-6
    PMID: 15194583
  10. 5-aminosalicylic acids and the risk of renal disease: A large british epidemiologic study.
    Van Staa TP, Travis S, Leufkens HG, Logan RF.
    Gastroenterology. (2004); 126: 1733-9
    PMID: 15188168
  11. Ischemic Stroke in Young Women. A Nested Case-Control Study Using the UK General Practice Research Database.
    Nightingale AL, Farmer RD.
    Stroke. (2004); 35: 1574-8
    PMID: 15143296
  12. Acute and clinically relevant drug-induced liver injury: a population based case-control study.
    De Abajo FJ, Montero D, Madurga M, Rodriguez LA.
    Br J Clin Pharmacol. (2004); 58: 71-80
    PMID: 15206996
  13. Autism and DPT vaccine in the UK
    Kaye JA, Jick H
    N Engl J Med (2004); 350 (26): 2722-3
    PMID: 15215496
  14. In-vitro fertilisation and childhood retinoblastoma
    Bradbury BD, Jick H
    Br J Clin Pharmacol. (2004); 58: 209-11.
    PMID: 15255804
  15. Antidepressants and the risk of suicidal behaviors
    Jick H, Kaye JA, Jick SS
    JAMA (2004); 292: 338-343
    PMID: 15265848
  16. Vaccination and allergic disease: a birth cohort study.
    McKeever TM, Lewis SA, Smith C, Hubbard R.
    Am J Public Health. (2004); 94: 985-9
    PMID: 15249303
  17. Risk of oesophageal cancer in Barrett's oesophagus and gastro-oesophageal reflux.
    Solaymani-Dodaran M, Logan RF, West J, Card T, Coupland C.
    Gut. (2004); 53: 1070-4
    PMID: 15370691
  18. Risk factors in carpal tunnel syndrome.
    Geoghegan JM, Clark DI, Bainbridge LC, Smith C, Hubbard R.
    J Hand Surg [Br]. (2004); 29: 315-20
    PMID: 15234492
  19. Risk of vascular disease in adults with diagnosed coeliac disease: a population-based study.
    West J, Logan RF, Card TR, Smith C, Hubbard R.
    Aliment Pharmacol Ther. (2004); 20: 73-9
    PMID: 15225173
  20. A cohort study of the effectiveness of influenza vaccine in older people, performed using the United kingdom general practice research database.
    Mangtani P, Cumberland P, Hodgson CR, Roberts JA, Cutts FT, Hall AJ.
    J Infect Dis. (2004); 190: 1-10
    PMID: 15195237
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  1. Agreement between GPRD smoking data: a survey of general practitioners and a population-based survey.
    Lewis JD, Brensinger C.
    Pharmacoepidemiol Drug Saf. (2004); 13: 437-41
    PMID: 15269927
  2. Venous thromboembolism associated with cyproterone acetate in combination with ethinyloestradiol (Dianette(R)): observational studies using the UK General Practice Research Database.
    Seaman HE, De Vries CS, Farmer RD.
    Pharmacoepidemiol Drug Saf. (2004); 13: 427-36
    PMID: 15269926
  3. Application of a propensity score to adjust for channelling bias with NSAIDs
    Morant SV, Pettitt D, MacDonald TM, Burke TA, Goldstein JL
    Pharmacoepidemiol Drug Saf. (2004); 13: 345-353
    PMID: 15170763
  4. Inhaled corticosteroids and the risk of fractures in children and adolescents
    Schlienger RG, Jick SS, Meier SR
    Pediatrics. (2004); 114: 469-73
    PMID: 15286232
  5. Risk of breast cancer among users of aspirin and other anti-inflammatory drugs.
    Garcia Rodriguez LA, Gonzalez-Perez A.
    Br J Cancer. (2004); 91: 525-9
    PMID: 15226764
  6. Statins and newly diagnosed diabetes
    Jick SS, Bradbury BD
    Br J Clin Pharmacol. (2004); 58: 303-9
    PMID: 15327590
  7. Medical event profiling of COPD patients.
    Hansell AL, Lam KA, Richardson S, Visick G, Soriano JB
    Pharmacoepidemiol Drug Saf. (2004); 13: 547-55
    PMID: 15317036
  8. Thimerosal exposure in infants and developmental disorders: a retrospective cohort study in the United Kingdom does not support a causal association
    Andrews N, Miller E, Grant A, Stowe J, Osborne V, Taylor B
    Pediatrics (2004); 114: 584-591
    PMID: 15342825
  9. Relative cost effectiveness of Depo-Provera, Implanon, and Mirena in reversible long-term hormonal contraception in the UK.
    Varney SJ, Guest JF.
    Pharmacoeconomics. (2004); 22(17): 1141-51
    PMID: 15612832
  10. Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction.
    Schlienger RG, Fischer LM, Jick H, Meier CR.
    Drug Saf. (2004); 27(14): 1157-65.
    PMID: 15554748
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Research Papers 2003

  1. Temporal trends in orchidopexy, great britain, 1992-1998
    Toledano MB, Hansell AL, Jarup L, Quinn M, Jick S, Elliott P
    Environ Health Perspect (2003); 111: 129-132
    PMID: 12515691
  2. Medical outcome of pregnancy in women with psychotic disorders and their infants in the first year after birth
    Howard LM, Goss C, Leese M, Thornicroft G
    Br J Psychiatry (2003); 182: 63-67
    PMID: 12509320
  3. Incidence of erectile dysfunction and characteristics of patients before and after the introduction of sildenafil in the United Kingdom: cross sectional study with comparison patients.
    Kaye JA, Jick H.
    Br Med J. (2003); 326: 424-425
    PMID: 12595382
  4. Cataract and the use of statins: a case-control study.
    Smeeth L, Hubbard R, Fletcher AE
    Q J Med (2003); 96: 337-343
    PMID: 12702782
  5. Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome?
    Ruigomez A, Garcia Rodriguez LA, Johansson S, Wallander MA
    Maturitas (2003); 44: 133-140
    PMID: 12590009
  6. MMR vaccine and idiopathic thrombocytopaenic purpura
    Black C, Kaye JA, Jick H
    Br J Clin Pharmacol. (2003); 55: 107-111
    PMID: 12534647
  7. Who receives lipid-lowering drugs: the effects of comorbidities and patient characteristics on treatment initiation?
    Yang CC, Jick SS, Testa MA
    Br J Clin Pharmacol (2003); 55: 288-298
    PMID: 12630980
  8. The risk of venous thromboembolism in women prescribed cyproterone acetate in combination with ethinyl estradiol: a nested cohort analysis and case-control study.
    Seaman HE, Vries CS, Farmer RD.
    Hum Reprod. (2003); 18: 522-6
    PMID: 12615818
  9. Differences in the use of combined oral contraceptives amongst women with and without acne.
    Seaman HE, Vries CS, Farmer RD.
    Hum Reprod. (2003); 18: 515-21
    PMID: 12615817
  10. Nonsteroidal antiinflammatory drugs as a trigger of clinical heart failure.
    Garcia Rodriguez LA, Hernandez-Diaz S.
    Epidemiology. (2003); 14: 240-6
    PMID: 12606892
  11. Increasing prevalence of asthma in UK primary care during the 1990s.
    Soriano JB, Kiri VA, Maier WC, Strachan D
    Int J Tuberc Lung Dis. (2003); 7: 415-21
    PMID: 12757040
  12. Medical conditions as risk factors for pressure ulcers in an outpatient setting.
    Margolis DJ, Knauss J, Bilker W, Baumgarten M.
    Age Ageing. (2003); 32: 259-64
    PMID: 12720610
  13. Children and the risk of fractures caused by oral corticosteroids.
    van Staa TP, Cooper C, Leufkens HG, Bishop N.
    J Bone Miner Res. (2003); 18: 913-8
    PMID: 12733732
  14. Neutropenia and agranulocytosis in England and Wales: incidence and risk factors.
    van Staa TP, Boulton F, Cooper C, Hagenbeek A, Inskip H, Leufkens HG.
    Am J Hematol. (2003); 72: 248-54
    PMID: 12666135
  15. Referral of children to specialists in the United States and the United Kingdom.
    Forrest CB, Majeed A, Weiner JP, Carroll K, Bindman AB.
    Arch Pediatr Adolesc Med. (2003); 15: 279-85
    PMID: 12622678
  16. Head lice diagnosed in general practice in the West Midlands between 1993 and 2000: a survey using the General Practice Research Database.
    Smith S, Smith G, Heatlie H, Bashford J, Ashcroft D, Millson D.
    Commun Dis Public Health (2003); 6: 139-43
    PMID: 12889294
  17. All-Cause Mortality and Vascular Events Among Patients with Rheumatoid Arthritis, Osteoarthritis, or No Arthritis in the UK General Practice Research Database.
    Watson DJ, Rhodes T, Guess HA
    J Rheumatol. (2003); 30: 1196-202
    PMID: 12784389
  18. The risk of stillbirth in pregnancies before and after the onset of diabetes.
    Wood SL, Jick H, Sauve R.
    Diabet Med. (2003);20 : 703-707
    PMID: 12925047
  19. Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs.
    MacDonald TM, Morant SV, Goldstein JL, Burke TA, Pettitt D.
    Gut. (2003); 52: 1265-1270
    PMID: 12912856
  20. Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids.
    Van der Linden PD, Sturkenboom MC, Herings RM, Leufkens HM, Rowlands S, Stricker BH.
    Arch Intern Med (2003); 163: 1801-7
    PMID: 12912715
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  1. The proportional Venn diagram of obstructive lung disease: two approximations from the United States and the United Kingdom.
    Soriano JB, Davis KJ, Coleman B, Visick G, Mannino D, Pride NB.
    Chest (2003); 124: 474-81
    PMID: 12907531
  2. Fracture risk in people with celiac disease: a population-based cohort study.
    West J, Logan RF, Card TR, Smith C, Hubbard R.
    Gastroenterology. (2003); 125: 429-36
    PMID: 12891545
  3. The incidence of bleeding complications associated with warfarin treatment in general practice in the United Kingdom.
    Hollowell J, Ruigomez A, Johansson S, Wallander MA, Garcia-Rodriguez LA.
    Br J Gen Pract. (2003); 53: 312-4
    PMID: 12879832
  4. Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics.
    Yang CC, Jick SS, Testa MA.
    Br J Clin Pharmacol. (2003); 56: 84-91
    PMID: 12848779
  5. Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture.
    Hubbard R, Farrington P, Smith C, Smeeth L, Tattersfield A.
    Am J Epidemiol. (2003); 158: 77-84
    PMID: 12835289
  6. Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibiotics.
    Strom BL, Schinnar R, Apter AJ, Margolis DJ, Lautenbach E, Hennessy S, Bilker WB, Pettitt D.
    N Engl J Med. (2003); 349: 1628-35
    PMID: 14573734
  7. The differences between ACE inhibitor-treated and calcium channel blocker-treated hypertensive patients.
    McInnes GT.
    J Clin Hypertens (Greenwich). (2003); 5: 337-44
    PMID: 14564134
  8. Antihypertensive treatment and erectile dysfunction in a cohort of type II diabetes patients.
    Blumentals WA, Brown RR, Gomez-Caminero A.
    Int J Impot Res. (2003); 15: 314-7
    PMID: 14562130
  9. Users of oral steroids are at a reduced risk of developing irritable bowel syndrome.
    Huerta C, Garcia Rodriguez LA, Wallander MA, Johansson S.
    Pharmacoepidemiol Drug Saf. (2003); 12: 583-8
    PMID: 14558181
  10. The risk of liver disorders in women prescribed cyproterone acetate in combination with ethinyloestradiol (Dianette): a nested case-control study using the GPRD.
    Seaman HE, de Vries CS, Farmer RD.
    Pharmacoepidemiol Drug Saf. (2003); 12: 541-50
    PMID: 14558177
  11. Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD).
    Carey IM, Cook DG, De Wilde S, Bremner SA, Richards N, Caine S, Strachan DP, Hilton SR.
    BMC Fam Pract. (2003); 4: 14
    PMID: 14516473
  12. Does influenza vaccination increase consultations, corticosteroid prescriptions, or exacerbations in subjects with asthma or chronic obstructive pulmonary disease?
    Tata LJ, West J, Harrison T, Farrington P, Smith C, Hubbard R.
    Thorax. (2003); 58: 835-9
    PMID: 14514932
  13. The incidence of sterilisation in the UK.
    Rowlands S, Hannaford P.
    BJOG. (2003); 110: 819-24
    PMID: 14511963
  14. A population based case-control study of cataract and inhaled corticosteroids.
    Smeeth L, Boulis M, Hubbard R, Fletcher AE.
    Br J Ophthalmol. (2003); 87: 1247-51
    PMID: 14507760
  15. Lipid-lowering drugs and the risk of depression and suicidal behavior.
    Yang CC, Jick SS, Jick H Arch Intern Med. (2003);163: 1926-32
    PMID: 12963565
  16. The use of inhaled corticosteroids in the United Kingdom and the Netherlands
    Van Staa TP, Cooper C, Leufkens HGM, Lammers JW, Suissa S
    Resp Med (2003); 97: 578-585
    PMID: 12735678
  17. Changes in antipsychotic drug prescribing by general practitioners in the United Kingdom from 1991-2000: a population-based observational study
    Kaye JA, Bradbury BD, Jick H
    Br J Clin Pharmacol (2003); 56: 596-575
    PMID: 14651732
  18. Cost and effectiveness of brinzolamide versus dorzolamide in current practice: an analysis based on the UK-GPRD database.
    Deschaseaux-Voinet C, Lafuma A, Berdeaux G.
    Journal of Medical Economics (2003); 6: 69-78
  19. Comparison of area-based inequality measures and disease morbidity in England, 1994-1998
    Hoare J
    Health Statistics Quarterly (2003); 18: 18-24
  20. The UK General Practice Research Database experience in COPD pharmacoepidemiology
    Soriano J.
    Eur Respir J (2003); 22 (Suppl. 43): 17s-22s
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  1. Early-life exposure to antibacterials and the subsequent development of hayfever in childhood in the UK: case-control studies using the General Practice Research Database and the Doctors' Independent Network.
    Bremner SA, Carey IM, DeWilde S, Richards N, Maier WC, Hilton SR., Strachan DP, Cook DG
    Clin Exp Allergy (2003); 33: 1518-1525
    PMID: 14616863
  2. Mortality in inflammatory bowel disease: a population-based cohort study.
    Card T, Hubbard R, Logan RFA.
    Gastroenterology (2003); 125: 1583-1590
    PMID: 14724808
  3. Epidemiology and Possible Causes of Autism
    Jick H, Kaye JA
    Pharmacotherapy (2003); 23: 1524-1530
    PMID: 14695031
  4. Prevalence of treated asthma and its management in general practice in England and Wales, 1994-1998
    Hoare J, Bruce M, Majeed A
    Health Statistics Quarterly (2003); 17: 15-22
  5. Use of alpha-blockers and the risk of hip/femur fractures.
    Souverein PC, Van Staa TP, Egberts AC, De la Rosette JJ, Cooper C, Leufkens HG.
    J Intern Med. (2003); 254(6):548-54.
    PMID: 14641795
  6. Lymphoma rates are low but increased in patients with psoriasis: results from a population-based cohort study in the United Kingdom.
    Gelfand JM, Berlin J, Van Voorhees A, Margolis DJ.
    Arch Dermatol. (2003); 139): 1425-9.
    PMID: 14623702
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Research Papers 2002

  1. Incidence of chronic atrial fibrillation in general practice and its treatment pattern
    Ruigomez A, Johansson S, Wallander MA, Rodriguez LA
    J Clin Epidemiol (2002); 55:358-363
    PMID: 11927203
  2. Association between acetaminophen or nonsteroidal antiinflammatory drugs and risk of developing ovarian, breast, or colon cancer
    Meier CR, Schmitz S, Jick H
    Pharmacotherapy (2002); 22: 303-309
    PMID: 11898889
  3. Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillation
    Ruigomez A, Johansson S, Wallander MA, Garcia Rodriguez LA
    BMC Cardiovasc Disord (2002); 2: 5
    PMID: 11897013
  4. Hormone replacement therapy and prevention of pressure ulcers and venous leg ulcers
    Margolis DJ, Knauss J, Bilker W
    Lancet (2002); 359: 675-677
    PMID: 11879867
  5. Incidence and natural history of Paget's disease of bone in England and Wales
    van Staa TP, Selby P, Leufkens HG, Lyles K, Sprafka JM, Cooper C
    J Bone Miner Res (2002); 17: 465-471
    PMID: 11878305
  6. Treatment patterns among newly diagnosed heart failure patients in general practice
    Johansson S, Wallander MA, Ruigomez A, Garcia R
    Eur J Clin Pharmacol (2002); 57: 813-817
  7. Venous leg ulcer: incidence and prevalence in the elderly
    Margolis DJ, Bilker W, Santanna J, Baumgarten M
    J Am Acad Dermatol (2002); 46: 381-386
    PMID: 11862173
  8. Levothyroxine treatment and occurrence of fracture of the hip
    Sheppard MC, Holder R, Franklyn JA
    Arch Intern Med (2002); 162: 338-343
    PMID: 11822927
  9. Statins and the risk of idiopathic venous thromboembolism
    Yang CC, Jick SS, Jick H
    Br J Clin Pharmacol (2002);53:101-105
  10. Early exposure to infections and antibiotics and the incidence of allergic disease: a birth cohort study with the West Midlands General Practice Research Database
    McKeever TM, Lewis SA, Smith C, Collins J, Heatlie H, Frischer M, Hubbard R
    J Allergy Clin Immunol (2002); 109: 43-50
    PMID: 11799364
  11. Antiepileptic drugs: coprescription of proconvulsant drugs and oral contraceptives: a national study of antiepileptic drug prescribing practice
    Shorvon SD, Tallis RC, Wallace HK
    J Neurol Neurosurg Psychiatry (2002); 72: 114-115
    PMID: 11784837
  12. The epidemiology and treatment of Bell's palsy in the UK
    Rowlands S, Hooper R, Hughes R, Burney P
    Eur J Neurol (2002);9:63-67
    PMID: 11784378
  13. Prescribing patterns in premenstrual syndrome
    Wyatt KM, Dimmock PW, Frischer M, Jones PW, O'Brien SP
    BMC Womens Health (2002); 2: 4
    PMID: 12086594
  14. Itraconazole and fluconazole and certain rare, serious adverse events
    Bradbury BD, Jick SS
    Pharmacotherapy (2002); 22: 697-700
    PMID: 12066960
  15. The Incidence and Prevalence of Pressure Ulcers among Elderly Patients in General Medical Practice
    Margolis DJ, Bilker W, Knauss J, Baumgarten M, Strom BL
    Ann Epidemiol (2002); 12: 321-325
    PMID: 12062919
  16. Validity and completeness of the General Practice Research Database for studies of inflammatory bowel disease
    Lewis JD, Brensinger C, Bilker WB, Strom BL
    Pharmacoepidemiol Drug Saf (2002); 11: 211-218
    PMID: 12051120
  17. The impact of coexisting connective tissue disease on survival in patients with fibrosing alveolitis
    Hubbard R, Venn A
    Rheumatology (2002); 4: 676-679
    PMID: 12048295
  18. Clinical risk factors for venous thromboembolus in users of the combined oral contraceptive pill
    Black C, Kaye JA, Jick H
    Br J Clin Pharmacol ( 2002); 53: 637-640
    PMID: 12047488
  19. The general fertility rate in women with psychotic disorders
    Howard LM, Kumar C, Leese M, Thornicroft G
    Am J Psychiatry (2002); 159: 991-997
    PMID: 12042188
  20. Peptic ulceration in general practice in England and Wales 1994-98: period prevalence and drug management
    Kang JY, Tinto A, Higham J, Majeed A
    Aliment Pharmacol Ther (2002); 16: 1067-1074
    PMID: 12030947
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  1. Lower risk of thromboembolic cardiovascular events with naproxen among patients with rheumatoid arthritis
    Watson DJ, Rhodes T, Cai B, Guess HA
    Arch Intern Med (2002); 162: 1105-1110
    PMID: 12020179
  2. Risk of clinical blood dyscrasia in a cohort of antibiotic users
    Huerta C, Garcia Rodriguez LA
    Pharmacotherapy (2002); 22: 630-636
    PMID: 12013362
  3. Drug or symptom-induced depression in men treated with alpha 1-blockers for benign prostatic hyperplasia? A nested case-control study
    Clifford GM, Farmer RD
    Pharmacoepidemiol Drug Saf (2002); 11: 55-61
    PMID: 11998552
  4. Risk of irritable bowel syndrome among asthma patients
    Huerta C, Garcia Rodriguez LA, Wallander MA, Johansson S
    Pharmacoepidemiol Drug Saf (2002); 11: 31-35
    PMID: 11998549
  5. Mode of delivery and risk of developing allergic disease
    McKeever TM, Lewis SA, Smith C, Hubbard R
    J Allergy Clin Immunol (2002); 109: 800-802
    PMID: 11994703
  6. Statin use, hyperlipidaemia, and the risk of breast cancer
    Kaye JA, Meier CR, Walker AM, Jick H
    Br J Cancer (2002); 86: 1436-1439
    PMID: 11986777
  7. Geriatric drug therapy and healthcare utilization in the United Kingdom
    Kennerfalk A, Ruigomez A, Wallander MA, Wilhelmsen L, Johansson S
    Ann Pharmacother (2002); 36: 797-803
    PMID: 11978154
  8. The effects of air pollution on general practitioner consultations for upper respiratory diseases in London
    Hajat S, Anderson HR, Atkinson RW, Haines A
    Occup Environ Med (2002); 59: 294-299
    PMID: 11983844
  9. Asociations of cold temperatures with GP consultations for respiratory and cardiovascular disease amongst the elderly in London
    Hajat S, Haines A
    Int J Epidemiol (2002); 31: 825-830
    PMID: 12177030
  10. Comparison of speciality referral rates in the United kingdom and the United states: retrospective cohort analysis
    Forrest CB, Majeed A, Weiner JP, Bindman AB
    Br Med J (2002); 325: 370-371
    PMID: 12183310
  11. Incident diabetes associated with antipsychotic use in the United Kingdom general practice research database
    Kornegay CJ, Vasilakis-Scaramozza C, Jick H
    J Clin Psychiatry (2002); 63: 758-762
    PMID: 12363114
  12. Use of nonsteroidal anti-inflammatory drugs and the risk of first-time acute myocardial infarction
    Schlienger RG, Jick H, Meier CR
    Br J Clin Pharmacol (2002); 54: 327-332
    PMID: 12236854
  13. Association between migraine and asthma: matched case-control study
    Davey G, Sedgwick P, Maier W, Visick G, Strachan DP, Anderson HR
    Br J Gen Pract (2002); 52: 723-727
    PMID: 12236275
  14. The importance of prenatal exposures on the development of allergic disease: a birth cohort study using the west midlands general practice database
    McKeever TM, Lewis SA, Smith C, Hubbard R
    Am J Respir Crit Care Med (2002); 166: 827-832
    PMID: 12231492
  15. Risk of acute liver injury in patients with diabetes
    Huerta C, Zhao SZ, Garcia Rodriguez LA
    Pharmacotherapy (2002); 22:1091-1096
    PMID: 12222543
  16. Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database
    Black C, Kaye JA, Jick H
    Br Med J (2002); 325: 419-421
    PMID: 12193358
  17. Does a fracture at one site predict later fractures at other sites? A British cohort study
    van Staa TP, Leufkens HG, Cooper C
    Osteoporos Int (2002); 13: 624-629
    PMID: 12181620
  18. Consultation rates from the general practice research database
    Rowlands S, Moser K
    Br J Gen Pract (2002); 52: 658-660
    PMID: 12171226
  19. Respiratory medications and risk of asthma death
    Lanes SF, Garcia Rodriguez LA, Huerta C
    Thorax (2002); 57: 683-686
    PMID: 12149527
  20. Can the General Practice Research Database be used to monitor the heath of babies and their mothers?
    Macfarlane A, Hockley C, McCandlish R, McNiece R
    Health Statistics Quarterly (2002); 13: 5-15
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  1. Age and sex-specific antibiotic prescribing patterns in general practice in England and Wales, 1994 to 1998
    Wrigley T, Tinto A, Majeed A
    Health Statistics Quarterly (2002); 14: 14-20
  2. Epilepsy prevalence and prescribing patterns in England and Wales
    Purcell B, Gaitatzis A, Sander JW, Majeed A
    Health Statistics Quarterly (2002); 15: 23-30
  3. Prevalence of diagnosed diabetes in general practice in England and Wales, 1994 to 1998
    Newnham A, Ryan R, Khunti K, Majeed A
    Health Statistics Quarterly (2002); 14: 5-13
  4. Etiology and frequency of rhabdomyolysis
    Black C, Jick H
    Pharmacotherapy (2002); 22: 1524-1526
    PMID: 12495162
  5. Accruing large numbers of patients in primary care trials by retrospective recruitment methods
    McCarney R, Fisher P, van Haselen R
    Complement Ther Med (2002); 10: 63-88
    PMID: 12481953
  6. Risk of serious skin disorders among users of oral antifungals: a population-based study
    Castellsague J, Garcia-Rodriguez LA, Duque A, Perez S
    BMC Dermatol (2002) 28; 2: 14
    PMID: 12456265
  7. Association between body mass index and liver disorders: an epidemiological study
    Meier CR, Krahenbuhl S, Schlienger RG, Jick H
    J Hepatol (2002); 37: 741-747
    PMID: 12445413
  8. An assessment of the independent effects of olanzapine and risperidone exposure on the risk of hyperlipidemia in schizophrenic patients
    Koro CE, Fedder DO, L'Italien GJ, Weiss S, Magder LS, Kreyenbuhl J, Revicki D, Buchanan RW
    Arch Gen Psychiatry (2002); 59: 1021-1026
    PMID: 12418935
  9. Survival in COPD patients after regular use of fluticasone propionate and salmeterol in general practice
    Soriano JB, Vestbo J, Pride NB, Kiri V, Maden C, Maier WC
    Eur Respir J (2002); 20: 819-825
    PMID: 12412670
  10. Inhaled corticosteroids and hip fracture: a population-based case-control study
    Hubbard RB, Smith CJ, Smeeth L, Harrison TW, Tattersfield AE
    Am J Respir Crit Care Med (2002) 15; 166: 1563-1566
    PMID: 12406825
  11. Utility of medical and drug history in fracture risk prediction among men and women
    van Staa TP, Leufkens HG, Cooper C
    Bone (2002); 31: 508-514
    PMID: 12398948
  12. Differences in the use of health services among people with and without epilepsy in the United Kingdom: socio-economic and disease-specific determinants.
    Gaitatzis A, Purcell B, Carroll K, Sander JWAS, Majeed A
    Epilepsy Res (2002); 50: 233-241
    PMID: 12200214
  13. Trends in the treatment of osteoporosis and types of drug treatments prescribed in general practice in England and Wales, 1994 to 1998.
    Bailey K, Ellis C, Majeed A.
    Health Statistics Quarterly (2002); 16: 5-13
  14. Prevalence of treated hypertension in general practice in England and Wales, 1994 to 1998.
    Ryan R, Majeed A.
    Health Statistics Quarterly (2002); 16: 14-18
  15. Population need for coronary revascularisation: are national targets credible?
    Martin RM, Hemingway H, Gunnell D, Karsch KR, Baumbach A, Frankel S
    Heart (2002); 88: 627-633
    PMID: 12433896
  16. Assessment of independent effect of olanzapine and risperidone on risk of diabetes among patients with schizophrenia: population based nested case-control study
    Koro CE, Fedder DO, L’Italien GJ, Weiss SS, Magder LS, Kreyenbuhl J, Revicki DA, Buchanan RW
    Br Med J. (2002); 325: 243-245
    PMID: 12153919
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Research Papers 2001

  1. Postmenopausal estrogen replacement therapy and the risk of Alzheimer’s disease
    Seshadri S, Zornberg GL, Derby LE, Myers MW, Jick H, Drachman DA
    Arch Neurol (2001); 58(3): 435-440
    PMID: 11255447
  2. Incidence of newly diagnosed heart failure in UK general practice
    Johansson S, Wallander M, Ruigomez A, Garcia Rodriguez LA
    Eur J Heart Fail (2001); 3(2): 225-231
    PMID: 11246061
  3. A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology
    Smeeth L, Hall AJ, Fombonne E, Rodrigues LC, Huang X, Smith PG
    BMC Public Health (2001); 1(1): 2
    PMID: 11231881
  4. Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations
    de Abajo FJ, Garcia Rodriguez LA
    BMC Clin Pharmacol (2001); 1(1): 1
    PMID: 11228592
  5. Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis
    Kaye JA, del Mar Melero-Montes M, Jick H
    Br Med J (2001); 322: 460-463
    PMID: 11222420
    http://bmj.com/cgi/content/full/322/7284/460  
  6. Epidemiologic assessment of the safety of conventional nonsteroidal anti-inflammatory drugs Hernandez-Diaz S, Garcia-Rodriguez LA
    Am J Med (2001); 110 (3 Suppl 1): 20-27
    PMID: 11173046
  7. Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs
    Garcia-Rodriguez LA, Huerta-Alvarez C
    Epidemiology (2001); 12: 88-93
    PMID: 11138826
  8. Public health impact of adverse bone effects of oral corticosteroids
    Van Staa TP., Abenhaim L., Cooper C., Zhang B., Leufkens HG
    Br J Clin Pharmacol (2001); 6:601-607
    PMID: 11422020
  9. Inequalities in treated heart disease and mental illness in England and Wales, 1994-1998
    Moser K
    Br J Gen Pract (2001); 467:438-444
    PMID: 11407047
  10. Steroids and risk of upper gastrointestinal complications
    Hernandez-Diaz S, Rodriguez LA
    Am J Epidemiol (2001); 153:1089-1093
    PMID: 11390328
  11. Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time-trend analysis
    Kaye JA, Maria Del Mar MM, Jick H
    West J Med (2001); 174:387-390
    PMID: 11222420
  12. Renal failure in patients with neurogenic lower urinary tract dysfunction
    Lawrenson R, Wyndaele JJ, Vlachonikolis I, Farmer C, Glickman S
    Neuroepidemiology (2001); 20:138-143
    PMID: 11359083
  13. Preferential prescribing of type of combined oral contraceptive pill by general practitioners to teenagers with acne
    Rowlands S, Devalia H, Lawrenson R
    Eur J Contracept Reprod Health Care (2001); 6:9-13
    PMID: 11334479
  14. Trends in antibiotic prescribing and associated indications in primary care from 1993 to 1997
    Frischer M, Heatlie H, Norwood J, Bashford J, Millson D, Chapman S
    J Public Health Med (2001); 23:69-73
    PMID: 11315698
  15. Use of statins and risk of fractures
    van Staa TP, Wegman S, de Vries F, Leufkens B, Cooper C
    JAMA (2001); 285:1850-1855
    PMID: 11308398
  16. Use of inhaled corticosteroids and risk of fractures
    van Staa TP, Leufkens HG, Cooper C
    J Bone Miner Res (2001); 16:581-588
    PMID: 11277277
  17. Lower urinary tract symptoms suggestive of benign prostatic obstruction - triumph: the role of general practice databases
    Logie JW, Clifford GM, Farmer RD, Meesen BP
    Eur Urol (2001); 39 Suppl 3:42-47
    PMID: 11275742
  18. Lower urinary tract symptoms suggestive of benign prostatic obstruction - triumph: design and implementation
    Chapple CR
    Eur Urol (2001); 39 Suppl 3:31-36
    PMID: 11275740
  19. Are users of lipid-lowering drugs at increased risk of peripheral neuropathy?
    Gaist D, Alberto L, Rodriguez G, Huerta C, Hallas J, Sindrup SH
    Eur J Clin Pharmacol (2001); 56:931-933
    PMID: 11800044
  20. Diagnosis and Initial Management of Stroke and Transient Ischemic Attack Across UK Health Regions From 1992 to 1996 : Experience of a National Primary Care Database
    Gibbs RG, Newson R, Lawrenson R, Greenhalgh RM, Davies AH
    Stroke (2001): 32: 1085-1090
    PMID: 11340214
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  1. Trends in the prevalence and management of atrial fibrillation in general practice in England and Wales, 1994-1998: analysis of data from the general practice research database
    Majeed A, Moser K, Carroll K
    Heart (2001); 86: 284-288
    PMID: 11514479
  2. The risk of liver damage associated with minocycline: a comparative study
    Seaman HE, Lawrenson RA, Williams TJ, MacRae KD, Farmer RD
    J Clin Pharmacol ( 2001); 4: 852-860
    PMID: 11504273
  3. The risk of obstructive airways disease in a glaucoma population
    Huerta C, Garcia Rodriguez LA, Moller CS, Arellano FM
    Pharmacoepidemiol Drug Saf (2001); 10: 157-163
    PMID: 11499855
  4. Use of selective serotonin reuptake inhibitors and risk of developing first-time acute myocardial infarction
    Meier CR, Schlienger RG, Jick H
    Br J Clin Pharmacol. (2001); 52:179-184
    PMID: 11488775
  5. Patterns of prescribing of nutritional supplements in the United Kingdom
    Gale CR, Edington J, Coles SJ, Martyn CN
    Clin Nutr (2001); 20: 333-337
    PMID: 11478831
  6. Consultations and referrals for dyspepsia in general practice-a one year database survey
    van Bommel MJ, Numans ME, de Wit NJ, Stalman WA
    Postgrad Med J (2001); 77: 514-518
    PMID: 11470932
  7. Otitis externa in UK general practice: a survey using the UK General Practice Research Database
    Rowlands S, Devalia H, Smith C, Hubbard R, Dean A
    Br J Gen Pract (2001); 51: 533-538
    PMID: 11462312
  8. Public health impact of adverse bone effects of oral corticosteroids
    van Staa TP, Abenhaim L, Cooper C, Zhang B, Leufkens HG
    Br J Clin Pharmacol (2001); 51: 601-607
    PMID: 11422020
  9. Incidence of ocular melanoma in the general population and in glaucoma patients
    Huerta C, Garcia Rodriguez LA
    J Epidemiol Community Health (2001); 55: 338-339
    PMID: 11297655
  10. Time trends in GP outpatient referrals
    Hodgson C, Ellis C
    Health Statistics Quarterly (2001); 10:14-19
  11. Antibiotic failure in the treatment of urinary tract infections in young women
    Lawrenson RA, Logie JW
    J Antimicrob Chemother (2001); 48: 895-901
    PMID: 11733475
  12. Epidemiology of fractures in England and Wales
    van Staa TP, Dennison EM, Leufkens HG, Cooper C
    Bone (2001); 29: 517-522
    PMID: 11728921
  13. The excess cost of acute exacerbations of chronic bronchitis in patients aged 45 and older in England and Wales
    McGuire A, Irwin DE, Fenn P, Gray A, Anderson P, Lovering A, MacGowan A.
    Value Health (2001); 4: 370-375
    PMID: 11705127
  14. Acetaminophen and the risk of renal and bladder cancer in the general practice research database
    Kaye JA, Wald Myers M, Jick H
    Epidemiology (2001); 12: 690-694
    PMID: 11679798
  15. Live attenuated polio vaccine and the risk of intussusception.
    Jick H, Vasilakis-Scaramozza C, Jick SS
    Br J Clin Pharmacol (2001); 52: 451-453
    PMID: 11678790
  16. Inflammatory Bowel Disease is not associated with an increased risk of lymphoma
    Lewis JD, Bilker WB, Brensinger C, Deren JJ, Vaughn DJ, Strom BL
    Gastroenterology (2001); 121:1080-1087
    PMID: 11740233
  17. Risk of cataract in patients treated with statins
    Schlienger RG, Haefeli WE, Jick H, Meier CR
    Arch Intern Med (2001);161: 2021-2026
    PMID: 11525705
  18. Siblings, multiple births, and the incidence of allergic disease: a birth cohort study using the West Midlands general practice research database
    McKeever TM, Lewis SA, Smith C, Collins J, Heatlie H, Frischer M, Hubbard R
    Thorax (2001); 56: 758-762
    PMID: 11562513
  19. Prevalence of ischaemic heart disease and its management with statins and aspirin in general practice in England and Wales, 1994 and 1998
    Ryan R, Majeed A
    Health Statistic Quartely (2001); 12, 34-39
  20. Prevalence of comorbid mental illness and drug use recorded in general practice: preliminary findings from the General Practice Research Database
    Frischer M, Akram G
    Drugs: education, prevention and policy (2001); 8: 276-280
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  1. Does oral polio vaccine cause intussusception in infants? Evidence from a sequence of three self-controlled cases series studies in the United Kingdom
    Andrews N, Miller E, Waight P, Farrington P, Crowcroft N, Stowe J, Taylor B
    Eur J Epidemiol (2001); 17: 701-706
    PMID: 12086086
  2. Association between air pollution and daily consultations with general practitioners for allergic rhinitis in London, United Kingdom.
    Hajat S, Haines A, Atkinson RW, Bremner SA, Anderson HR, Emberlin J
    J Epidemiol (2001);153:704-714
    PMID: 11282799
  3. Use of the combined oral contraceptive pill by under 16s
    Rowlands S, Devalia H, Lawrenson R
    J Fam Plann Reprod Health Care (2001); 27: 17-19
    PMID: 12457541
  4. The risk of cataract among users of inhaled steroids
    Jick SS, Wasilakis-Scaramozza C, Maier WC.
    Epidemiology (2001); 12: 229-234
    PMID: 11246585
  5. Prevalence and management of heart failure in England and Wales, 1994-98
    Ellis C, Gnani S, Majeed A
    Health Statistics Quarterly (2001); 11: 17-24
  6. Lipid-lowering drugs and risk of myopathy: a population-based follow-up study
    Gaist D, Garcia Rodriguez LA, Huerta C, Hallas J, Sindrup SH
    Epidemiol (2001); 12: 565-569
    PMID: 11505177
  7. The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen and combination of these agents
    Garcia Rodriguez LA, Hernandez-Diaz S
    Arthritis Research (2001); 3: 98-101
    PMID: 11178116
  8. Relative risk of upper gastrointestinal complications among users of acetaminophen and nonsteroidal anti-inflammatory drugs
    Garcia Rodriguez LA, Hernandez Dias S
    Epidemiol (2001); 12: 570-576
    PMID: 11505178
  9. Gender and drug treatment as determinants of mortality in a cohort of heart failure patients
    Ruigomez A, Johannson S, Wallander M-A, Garcia Rodriguez LA
    Eur J Epidemiol (2001); 17: 329-335
    PMID: 11767958
  10. Risk of venous thromboembolism with cyproterone or levonorgestrel contraceptives
    Vasilakis-Scaramozza C, Jick H
    Lancet (2001); 358: 1427-1429
    PMID: 11705493
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Research Papers 2000

  1. Angiotensin-converting enzyme inhibitors, calcium channel blockers and breast cancer
    Meier CR, Derby LE, Jick SS, Jick H
    Arch Int Med (2000); 160: 349-353
    PMID: 10668837
  2. The risk of acute pancreatitis associated with acid-suppressing drugs
    Eland IA, Huerta-Alvarez C, Stricker BHCH, Garcia Rodriguez LA
    Br J Clin Pharmacol (2000); 49: 473-478
    PMID: 10792205
  3. Antihypertensive drugs and the risk of idiopathic aplastic anemia
    Myers MW, Vasilakis C, Kaufman MR, Jick H
    Br J Clin Pharmacol (2000); 49: 604-608
    PMID: 10848725
  4. Intracranial hemorrhage and use of selective serotonin reputake inhibitors
    De Abajo FJ, Jick H, Derby LE, Jick SS, Schmitz SM
    Br J Clin Pharmacol (2000); 50: 43-47
    PMID: 10886117
  5. A comparison of the risks of venous thromboembolic disease in association with different combined oral contraceptives
    Farmer RDT, Lawrenson RA, Todd J-C, Williams TJ, MacRae KD, Tyrer F, Leydon GM
    Br J Clin Pharmacol (2000); 49: 580-590
    PMID: 10848722
  6. Validation of the diagnosis of venous thromboembolism in general practice database studies
    Lawrenson RA, Todd J-C, Leydon GM, Williams TJ, Farmer RDT
    Br J Clin Pharmacol (2000); 49: 591-596
    PMID: 10848723
  7. Incidence of venous thromboembolism in users of combined oral contraceptives. Methods for identifying cases and estimating person time at risk must be detailed.
    Jick H.
    Br Med J (2000); 320(7226): 57
    PMID: 10617543
    http://bmj.com/cgi/content/full/320/7226/57  
  8. Risk of suicide among users of calcium channel blockers: population based, nested case-control study
    Gasse C, Derby LE, Vasilakis C, Jick H
    Br Med J (2000); 320: 1251
    PMID: 10797037
    http://bmj.com/cgi/content/full/320/7244/1251  
  9. Effect of 1995 pill scare on rates of venous thromboembolism among women taking combined oral contraceptives: analysis of General Practice Research Database
    Farmer RDT, Williams TJ, Simpson EL, Nightingale AL
    Br Med J (2000); 321: 477-479
    PMID: 10948026
    http://bmj.com/cgi/content/full/321/7259/477  
  10. Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: a pooled analysis of published studies and a new population based study
    Garcia Rodriguez LA, Huerta-Alvarez C
    Epidemiology (2000); 11: 376-381
    PMID: 10874542
  11. Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women
    Garcia Rodriguez LA, Varas C, Patrono C
    Epidemiology (2000); 11: 382-387
    PMID: 10874543
  12. Risk of cataract among users of intranasal corticosteroids
    Derby LE, Maier WC
    J Aller Clin Immunol (2000); 105: 912-916
    PMID: 10808171
  13. Use of oral corticosteroids and risk of fractures
    van Staa TP, Leufkens H, Abenhaim L, Zhang B, Cooper C
    J Bone Miner Res (2000); 15(6): 993-1000
    PMID: 10841167
  14. Oral corticosteroids and fracture risk: relationship to daily and cumulative doses.
    van Staa TP, Leufkens HG, Abenhaim L, Zhang B, Cooper C.
    Rheumatology (Oxford). 2000; 39(12):1383-9.
    PMID: 11136882
  15. Overall mortality among patients surviving an episode of peptic ulcer bleeding
    Ruigomez A, Garcia Rodriguez LA, Hasselgren G, Johansson S, Wallander MA
    J Epidemiol Commun Health (2000); 54: 130-133
    PMID: 10715746
  16. HMG-CoA reductase inhibitors and the risk of fractures
    Meier CR, Schlienger RG, Kraenzlin ME, Schlegel B, Jick H
    JAMA (2000); 283: 3205-3210
    PMID: 10866867
  17. The risk of gastrointestinal bleed, myocardial infarction, and newly diagnosed hypertension in users of meloxicam, diclofenac, naproxen and piroxicam
    Jick SS
    Pharmacotherapy (2000); 20: 741-744
    PMID: 10907963
  18. Effect of anti-inflammatory drugs on overall risk of common cancer: case-control study in general practice research database
    Langman MJS, Cheng KK, Gilman EA, Lancashire R J
    Br Med J (2000); 320: 1642-1646
    PMID:10856067
    http://bmj.com/cgi/content/full/320/7250/1642  
  19. Exposure to antidepressants and the risk of cryptogenic fibrosing alveolitis: a case-control study
    Hubbard R, Venn A, Britton J
    Eur Respir J (2000); 16: 409-413
    PMID: 11028652
  20. Medical events and resources utilisation in cancer-pain patients treated with strong opioids: An analysis of the UK general practice research database
    Tooley JH, Cookson RF, Jones M, Nuyts GD
    J Outcomes Res (2000); 4:1-14
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  1. Adult height and cryptogenic fibrosing alveolitis: a case-control study using the UK general practice research database
    Hubbard R, Venn A
    Thorax (2000); 55: 864-866
    PMID: 10992540
  2. Antibiotics in the prevention and treatment of coronary heart disease.
    Meier CR
    J Infect Dis (2000); 181: S558-S562
    PMID: 10839758
  3. Recent trends in physician diagnosed COPD in women and men in the UK
    Soriano JB, Maier WC, Egger P. Visick G, Thakrar B, Sykes J, Pride NB
    Thorax. (2000);55: 789-794
    PMID: 10950900
  4. Population-based study on incidence, risk factors, clinical complications and drug utilisation associated with influenza in the United Kingdom
    Meier CR, Napalkov PN, Wegmueller Y, Jefferson T, Jick H
    Eur J Clin Microbiol Infect Dis (2000); 19: 834-42
    PMID: 11152308
  5. Isotretinoin use and risk of depression, psychotic symptoms, suicide and attempted suicide
    Jick SS, Kremers HM, Vasilakis-Scaramozza C
    Arch Dermatol (2000); 136:1231-1236
    PMID: 11030769
  6. Incidence of first-time idiopathic seizures in users of tramadol
    Gasse C, Derby LE, Vasilakis-Scaramozza C, Jick H
    Pharmacotherapy (2000); 20: 629-634
    PMID: 10853617
  7. The incidence of breast cancer in the general practice research database compared with national cancer registration data
    Kaye JA, Derby LE, Melero-Montes MM, Quinn M, Jick H
    Br J Cancer (2000);83(11):1556-1558
    PMID: 11076668
  8. Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study
    Zornberg GL, Jick H
    Lancet (2000); 356:1219-1223
    PMID: 11072939
  9. Statins and the risk of dementia
    Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman, DA
    Lancet (2000); 356: 1627-1631
    PMID: 11089820
  10. Risk of venous thromboembolism among users of third generation oral contraceptives compared with users of oral contraceptives with levonorgestrel before and after 1995: cohort and case-control analysis
    Jick H, Kaye JA, Vasilakis-Scaramozza C, Jick SS
    Br Med J (2000); 321:1190-1195
    PMID: 11073511
    http://bmj.com/cgi/content/full/321/7270/1190  
  11. Oral corticosteroids and fracture risk: relationship to daily and cumulative doses
    van Staa TP, Leufkens HG, Abenhaim L, Zhang B, Cooper C
    Rheumatology (2000); 39:1383-1389
    PMID: 11136882
  12. Use of oral corticosteroids and risk of fractures.
    Van Staa TP, Leufkens HG, Abenhaim L, Zhang B, Cooper C.
    J Bone Miner Res. 2000 Jun;15(6):993-1000.
    PMID: 10841167
  13. A UK general practice database study of prevalence and mortality of people with neural tube defects
    Lawrenson R, Wyndaele JJ, Viachonikolis I, Farmer C, Glickman S
    Clin Rehabil (2000); 14(6): 627-630
    PMID: 11128738
  14. How do symptoms indicative of BPH progress in real life practice? The UK experience
    Clifford GM, Logie J, Farmer RD
    Eur Urol (2000); 38(Suppl 1): 48-53
    PMID: 11111208
  15. Venous thromboembolism and combined oral contraceptives: does the type of progestogen make a difference?
    Lawrenson R, Farmer R
    Contraception (2000); 62(Suppl 2): S21-S28
    PMID: 11102599
  16. A comparison of trends in problematic drug misuse from two reporting systems
    Frischer M, Heatlie H, Milison D, Lowdell J, Hickman M, Chapman S, Bashford J, Norwood J
    J Pub Health Med (2000); 22: 362-367
    PMID: 11077911
  17. Age, sex and practice variations in the use of statins in general practice in England and Wales
    Majeed A, Moser K, Maxwell R
    J Pub Health Med (2000); 22: 275-279
    PMID: 11077897
  18. Use of nonsteroidal anti-inflammatory drugs and risk of fractures
    van Staa TP, Leufkens HG, Cooper C
    Bone (2000); 27:563-568
    PMID: 11033453
  19. Repeated use of hormonal emergency contraception by younger women in the UK
    Rowlands S, Devalia H, Lawrenson R, Logie J, Ineichen B
    Br J Fam Plann (2000); 26:138-143
    PMID: 10920289
  20. Hormone replacement therapy and incidence of acute myocardial infarction: A population-based nested case-control study
    Varas-Lorenzo C, Garcia Rodriguez LA, Pérez-Gutthann S, Duque-Oliart A
    Circulation (2000) 101: 2572-2578
    PMID: 10840007
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  1. Are schizophrenia or antipsychotic drugs a risk factor for cataracts?
    Ruigomez A, Garcia Rodriguez LA, Dev VJ, Arellano F, Raniwala J
    Epidemiology (2000); 11: 620-623
    PMID: 11055620
  2. Epidemiology of pneumothorax in England
    Gupta D, Hansell A, Nichols T, Duong T, Ayres JG, Strachan D
    Thorax (2000); 55:666-671
    PMID: 10899243
  3. Multiple sclerosis and antecedent infections: a case-control study
    Marrie RA, Wolfson C, Sturkenboom MC, Gout O, Heinzlef O, Roullet E, Abenhaim L
    Neurology (2000); 54: 2307-2310
    PMID: 10881258
  4. Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study
    Hubbard R, Venn A, Lewis S, Britton J
    Am J Respir Crit Care Med (2000); 161:5-8
    PMID: 10619790
  5. Use of oral corticosteroids in the United Kingdom
    van Staa TP, Leufkens HG, Abenhaim L, Begaud B, Zhang B, Cooper C
    QJ Med (2000); 93:105-111
    PMID: 10700481
  6. Detection of colorectal tumor and inflammatory bowel disease during follow-up of patients with initial diagnosis of irritable bowel syndrome
    Garcia Rodriguez LA, Ruigomez A, Wallander MA, Johansson S, Olbe I
    Scandinav J Gastroenterol (2000); 35:306-311
    PMID: 10766326
  7. Overall mortality among patients surviving an episode of peptic ulcer bleeding
    Ruigomez A, Garcia Rodriguez LA, Hasselgren G, Johansson S, Wallander MA
    J Epidemiol Commun Health (2000); 54:130-133
    PMID: 10715746
  8. How do symptoms indicative of BPH progress in real life practice? The UK Experience
    Clifford GM, Logie J, Farmer RD
    Eur Urol (2000); 38 Suppl S1: 48-53
    PMID: 11111208
  9. The effects of age, body mass index, smoking and general health on the risk of venous thromboembolism in users of combined oral contraceptives
    Nightingale AL, Lawrenson RA, Simpson EL, Williams TJ, MacRae KD, Farmer RD
    Eur J Contracept Reprod Health Care (2000); 5:265-274
    PMID: 11245554
  10. Ratio of inhaled corticosteroid to bronchodilator and hospital referral for asthma: a patient level analysis using the General Practice Research Database
    Frischer M, Heatlie H, Chapman S, Bashford J, Norwood J, Millson D
    Curr Med Res Opin (2000); 16; 8-13
    PMID: 16422029
  11. Defining the spectrum of appropriate prescribing: implications for effective medicines management
    Frischer M, Heatlie H, Chapman S, Millson D
    Int J Pharm Med (2000); 14: 17-21
  12. Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with increasing consulting rates for depressive illness?
    Millson D, Frischer M, Croft P, Goadsby P
    Cephalalgia (2000); 20: 732-737
    PMID: 11167903
  13. Patterns of prescription of PC4 by general practitioners in England and Wales.
    Ineichen B, Logie J, Rowlands S, Lawrenson R
    Eur J Contracept Reprod Health Care (2000); 5: 241-247
    PMID: 11245551
  14. Hyperemesis gravidarum and the sex of the baby
    Melero Montes MM, Jick H
    Epidemiology (2000); 12: 123-4
    PMID: 11176253
  15. Baseline risk of gastro-intestinal disorders among new users of meloxicam, ibuprofen, diclofenac, naproxen and indomethacin
    Lanes SF, Garcia Rodriguez LA, Hwang E
    Pharmacoepidemiol & Drug Safety (2000); 9: 113-117
    PMID: 19025810
  16. Morbidity and treatment data from general practice 1998 (England and Wales)
    Office for National Statistics
    Health Statistics Quarterly(2000); 8: 81-86
  17. The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results
    van Staa TP, Abenhaim L, Cooper C, Zhang B, Leufkens HGM
    Pharmacoepidemiol & Drug Safety (2000); 9: 359-366
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Research Papers 1999

  1. Prevalence of asthma in general practice
    Office for National Statistics
    Asthma J(1999); 4: 79-80
  2. Health of older people: disease prevalence, prescription and referral rates, England and Wales 1996
    Carter M, Moser K, Kelly S
    Health Statistics Quarterly (1999); 4: 9-15
  3. Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study
    De Abajo FJ, Garcia Rodriguez LA, Montero D
    Br Med J (1999); 319: 1106-1109
    PMID: 10531103
    http://bmj.com/cgi/content/full/319/7217/1106  
  4. Use of dexfenfluramine, fenfluramine and phentermine and the risk of stroke
    Derby LE, Myers MW, Jick H
    Br J Clin Pharmacol (1999); 47: 565-569
    PMID: 10336582
  5. Switching between Metered Dose Inhalers (MDIs) and Dry Powder Inhalers (DPIs) in airways disease: an analysis of age-specific rates using the General Practice Research Database
    Frischer M, Heatlie H, Chapman S, Bashford J, Norwood J
    J Appl Ther Res (1999); 2: 253-259
  6. Should the corticosteroid to bronchodilator ratio be promoted as a quality prescribing marker?
    Frischer M, Heatlie H, Chapman S, Norwood J, Bashford J, Milison D
    Public Health (1999); 113: 247-250
    PMID: 10557120
  7. Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study
    Garcia Rodriguez LA, Ruigomez A
    Br Med J (1999); 318: 565-566
  8. Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed
    Garcia Rodriguez LA, Ruigomez A
    Epidemiology(1999); 10: 228-232
    PMID: 10230829
  9. Association of air pollution with daily GP consultations for asthma and other lower respiratory conditions in London
    Hajat S, Goubert SA, Haines A, Atkinson RW, Anderson HR
    Thorax (1999); 54: 597-605
    PMID: 10377204
  10. Use of the General Practice Research Database (GPRD) for respiratory epidemiology: a comparison with the 4th Morbidity survey in general practice (MSGP4)
    Hansel A, Hollowell J, Nichols T, McNiece R, Strachan D
    Thorax (1999); 54: 413-419
    PMID: 10212105
  11. Pregnancy outcomes after maternal exposure to fluconazole
    Jick SS
    Pharmacotherapy (1999); 19: 221-222
    PMID: 10030772
  12. Risk of idiopathic cerebral haemorrhage in women on oral contraceptives with differing progestagen components (research letter)
    Jick SS, Myers MW, Jick H
    Lancet (1999); 354: 302-303
    PMID: 10440310
  13. Hormone Replacement Therapy: patterns of use studied through British general practice computerized records
    Lawrence M, Jones L, Lancaster T, Daly E
    Family Practice (1999); 16: 335-342
    PMID: 10493702
  14. Age- and sex-specific antibiotic prescribing patterns in general practice in England and Wales in 1996
    Majeed A, Moser K
    Br J Gen Pract (1999); 49: 735-736
    PMID: 10756619
  15. Prescribing for patients with asthma by general practitioners in England and Wales 1994-1996
    Majeed A, Moser K
    Health Statistics Quarterly (1999); 1: 16-20
  16. Prevalence and management of heart failure in general practice in England and Wales 1994-96
    Majeed A, Moser K
    Health Statistics Quarterly (1999); 4: 5-8
  17. Antibiotics and risk of subsequent first-time acute myocardial infarction
    Meier CR, Derby LE, Jick SS, Vasilakis C, Jick H
    JAMA (1999); 281: 427-431
    PMID: 9952202
  18. Prevalence of treated chronic diseases in general practice in England and Wales - trends over time and variations by the ONS area classification
    Moser K, Majeed A
    Health Statistics Quarterly (1999); 2: 25-32
  19. Low-dose diclofenac, naproxen and ibuprofen cohort study
    Perez Gutthann S, Garcia Rodriguez LA, Duque Oliart A, Varas-Lorenzo C
    Pharmacotherapy (1999); 19(7): 854-859
    PMID: 10417034
  20. Use of cimetidine, omeprazole and ranitidine in pregnant women and pregnancy outcomes
    Ruigomez A, Garcia Rodriguez LA, Cattaruzzi C, Troncon MG, Agostinis L, Wallander MA, Johansson S
    Am J Epidemiol (1999); 150: 476-481
    PMID: 10472947
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  1. One-year follow-up of newly diagnosed irritable bowel syndrome patients
    Ruigomez A, Wallander MA, Johansson S, Garcia Rodriguez LA
    Aliment Pharmacol and Ther (1999); 13: 1097-1102
    PMID: 10468687
  2. Minocycline and lupus-like syndrome in acne patients
    Sturkenboom MCJM, Meier CR, Jick H, Stricker BHCH
    Arch Int Med (1999); 159: 493-497
    PMID: 10074958
  3. Risk of idiopathic venous thromboembolism in users of progestagens alone (research letter)
    Vasilakis C, Jick H, Melero-Montes MM
    Lancet (1999); 354: 1610-1611
    PMID: 10560680
  4. The risk of venous thromboembolism in users of postcoital contraceptive pills
    Vasilakis C, Jick SS, Jick H
    Contraception (1999); 59: 79-83
    PMID: 10361621
  5. Frequency of liver disease in type 2 diabetes patients treated with oral antidiabetic agents
    Jick SS, Stender M, Myers MW
    Diabetes Care (1999); 22: 2067-2071
    PMID: 10587844
  6. Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs
    De Abajo FJ, Garcia Rodriguez LA
    Br J Clin Pharmacol (1999); 47: 307-313
    PMID: 10215756
  7. A cohort study on the risk of acute liver injury among users of ketoconazole and other antifungal drugs
    Garcia Rodriguez LA, Duque A, Castellsague J, Perez Gutthann S, Stricker BHCH
    Br J Clin Pharmacol (1999); 48: 847-852
    PMID: 10594489
  8. Oral contraceptives and venous thromboembolic disease. Analyses of the UK General Practices Research Database and the UK MediPlus Database
    Todd J-C, Williams TJ, MacRae K
    Human Reproduction update (1999); 5:688-706
    PMID: 10652979
  9. Costs of breast cancer treatment in the United Kingdom
    Dolan P, Torgerson DJ, Wolstenholme J
    Breast (1999); 8: 205-207
    PMID: 14731442
  10. Outcomes of undernutrition in patients in the community with cancer or cardiovascular disease
    Edington J, Winter PD, Coles SJ, Gale CR, Martyn CN
    Proceedings of the Nutrition Society (1999); 58: 655-661
    PMID: 10604199
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Research Papers 1998

  1. Recent epidemiological studies of the association between hormone replacement therapy and venous thromboembolism. A review.
    Castellsague J, Gutthann SP, Rodriguez LG
    Drug Safety (1998); 18:117-123
    PMID: 9512918
  2. Why are patients prescribed proton pump inhibitors? Retrospective analysis of link between morbidity and prescribing in the General Practice Research Database
    Bashford JNR, Norwood J, Chapman SR
    Br Med J (1998); 317: 452-456
    PMID: 9703528
    http://bmj.com/cgi/content/full/317/7156/452  
  3. Antiepileptics and blood dyscrasia: a cohort study
    Blackburn SC, Duque Oliart A, Garcia Rodriguez LA, Perez Gutthann S
    Pharmacotherapy (1998); 18: 1277-1283
    PMID: 9855327
  4. Recent developments in general practice computing
    De Lusignan S, Brown A, Majeed A
    Clinician in Management (1998); 7: 148-154
  5. Appendectomy protects against ulcerative colitis
    Derby LE, Jick H
    Epidemiology (1998); 9: 205-207
    PMID: 9504292
  6. The cost of treating osteoporotic fractures in the United Kingdom female population
    Dolan P, Togerson DJ
    Osteopor Int (1998); 8: 611-617
    PMID: 10326069
  7. Risk of hospitalization for upper gastrointestinal tract bleeding associated with ketorolac, other nonsteroidal anti-inflammatory drugs, calcium antagonists and other antihypertensive drugs
    Garcia Rodriguez LA, Cattaruzzi C, Troncon MG, Agostinis L
    Arch Int Med (1998); 158: 33-39
    PMID: 9437376
  8. Use of the UK General Practice Research Database for pharmacoepidemiology.
    García Rodríguez LA, Pérez Gutthann S.
    Br J Clin Pharmacol. 1998 May; 45(5):419-25.
    PMID: 9643612
  9. Comparison of mortality from peptic ulcer bleed between patients with or without peptic ulcer antecedents
    Garcia Rodriguez LA, Ruigomez A, Hasselgren G, Wallander MA, Johansson S
    Epidemiology (1998); 9: 452-456
    PMID: 9647912
  10. Presence of diabetes related complication at the time of NIDDM diagnosis: an important prognostic factor
    Garcia Rodriguez LA, Ruigómez A, Hasselgren W, Wallander MA, Johansson S
    Eur J Epidemiol (1998); 14: 439-445
    PMID: 9744675
  11. Relationship between the regional and national incidence of transient ischaemic attack and stroke and performance of carotid endarterectomy
    Gibbs RGJ, Todd J-C, Irvine C, Lawrenson R, Newson R, Greenhalgh RM, Davies AH
    Eur J Vasc Endovasc Surg (1998); 16: 47-52
    PMID: 9715716
  12. Potential for suicide prevention in primary care? An analysis of factors associated with suicide
    Haste F, Charlton J, Jenkins R
    Br J Gen Pract (1998); 48: 1759-1763
    PMID: 10198484
  13. Antidepressant exposure and risk of cryptogenic fibrosing alveolitis: a case-control study using the General Practice Research Database
    Hubbard R, Venn A, Lewis SA, Britton J
    Thorax (1998); 53: S44
  14. Exposure to commonly prescribed drugs and the etiology of cryptogenic fibrosing alveolitis: a case-control study
    Hubbard R, Venn A, Smith C, Cooper M, Johnston I, Britton I
    Am J Respir Crit Care Med (1998); 157: 743-747
    PMID: 9517585
  15. Influenza vaccine uptake and distribution in England and Wales, July 1989-June 1997
    Irish C, Alli M, Gilham C, Joseph C, Watson J
    Health Trends (1998); 30(2)
  16. The risk of seizures associated with tramadol
    Jick H, Derby LE, Vasilakis C, Fife D
    Pharmacotherapy (1998); 18: 607-611
    PMID: 9620111
  17. A population-based study of users of appetite-suppressant drugs on the risk of cardiac valve regurgitation.
    Jick H, Vasilakis C, Weinrauch LA, Meier CR, Jick SS, Derby LE
    N Engl J Med (1998); 339: 719-724
    PMID: 9731087
  18. Pregnancies and terminations after 1995 warning about third-generation oral contraceptives (research letter)
    Jick SS, Vasilakis C, Jick H
    Lancet (1998); 351: 1404-1405
    PMID: 9593415
  19. A study of the relation of exposure to quinolones and suicidal behaviour
    Jick SS, Vasilakis C, Martinez C, Jick H
    Br J Clin Pharmacol (1998); 45: 77-81
    PMID: 9489598
  20. Risk of serious haematological toxicity associated with the use of chloramphenicol eye drops in a British general practice database
    Lancaster T, Swart AM, Jick H
    Br Med J (1998); 316: 667
    PMID: 9522792
    http://bmj.com/cgi/content/full/316/7132/667  
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  1. Effect of nutritional status on use of health care resources by patients with chronic disease living in the community
    Martyn CN, Winter PD, Coles SJ, Edington J
    Clin Nut (1998); 17: 119-123
    PMID: 10205328
  2. Tamoxifen and risk of idiopathic venous thromboembolism
    Meier CR, Jick H
    Br J Clin Pharmacol (1998); 45: 608-612
    PMID: 9663819
  3. Acute respiratory tract infections and risk of first-time acute myocardial infarction
    Meier CR, Jick SS, Derby LE, Vasilakis C, Jick H
    Lancet (1998); 351: 1467-1471
    PMID: 9605802
  4. Postmenopausal estrogen replacement therapy and the risk of developing systemic lupus erythematosus or discoid lupus
    Meier CR, Sturkenboom MCJM, Cohen AS, Jick H
    J Rheumatol (1998); 25: 1515-1519
    PMID: 9712093
  5. Terfenadine and risk of acute liver disease
    Myers MW, Jick H
    Br J Clin Pharmacol (1998); 46: 251-253
    PMID: 9764966
  6. Mortality in people taking selegiline: observational study
    Thorogood M, Armstrong B, Nichols T, Hollowell J
    Br Med J (1998); 317: 252-254
    PMID: 9677215
    http://bmj.com/cgi/content/full/317/7153/252  
  7. Use of cyclical etidronate and prevention of non-vertebral fractures
    van Staa TP, Abenhaim L, Cooper C
    Br J Rheumatol (1998); 37: 87-94
    PMID: 9487256
  8. Postmarketing surveillance of the safety of cyclic etidronate
    van Staa TP, Leufkens H, Abenhaim L, Cooper C
    Pharmacotherapy (1998); 18(5): 1121-1128
    PMID: 9758324
  9. Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2 052 922 and age-specific fertility rates of women with epilepsy
    Wallace H, Shorvon S, Tallis R
    Lancet (1998); 352: 1970-1973
    PMID: 9872246
  10. Prescribing by general practitioners after an osteoporotic fracture
    Torgerson DJ, Dolan P
    Ann Rheumatic Diseases (1998); 25: 1515-1519
    PMID: 9771215
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Research Papers 1997

  1. Gastric acid, acid-suppressing drugs and bacterial gastroenteritis: how much of a risk?
    Garcia Rodriguez LA, Ruigomez A
    Epidemiology (1997); 8: 571-574
    PMID: 9270961
  2. A review of epidemiologic research on drug-induced acute liver injury using the General Practice Research Database in the United Kingdom
    Garcia Rodriguez LA, Ruigómez A, Jick H
    Pharmacotherapy (1997); 17: 721-728
    PMID: 9250549
  3. Renal disease and acid-suppressing drugs
    Garcia Rodriguez LA, Wallander MA, Johansson S, Bjork S
    Pharmacoepidemiology and Drug Safety (1997); 6: 247-251
    PMID: 15073775
  4. The risk of acute liver injury associated with cimetidine and other acid-suppressing anti-ulcer drugs
    Garcia Rodriguez LA, Wallander MA, Stricker BH
    Br J Clin Pharmacol (1997); 43: 183-188
    PMID: 9131951
  5. Thunderstorm-associated asthma: the effect on GP consultations
    Hajat S, Goubet SA, Haines A
    Br J Gen Pract (1997); 47: 639-641
    PMID: 9474828
  6. The General Practice Research Database: quality of morbidity data
    Hollowell J
    Populat Trends (1997); 87: 36-40
    PMID: 9134574
  7. Calcium-channel blockers and risk of cancer
    Jick H, Jick SS, Derby LE, Vasilakis C, Myers MW, Meier CR
    Lancet (1997); 349: 525-528
    PMID: 9186407
  8. Antihypertensive drugs and fatal myocardial infarction in persons with uncomplicated hypertension
    Jick H, Vasilakis C, Derby LE
    Epidemiology (1997); 8(4): 446-448
    PMID: 9209862
  9. Ciprofloxacin safety in a pediatric population
    Jick SS
    Ped Infect Dis J(1997); 16: 130-134
  10. Anticonvulsants and congenital malformations
    Jick SS, Terris BZ
    Pharmacotherapy (1997); 17: 561-564
    PMID: 9165559
  11. Omeprazole, other antiulcer drugs and newly diagnosed gout
    Meier CR, Jick H
    Br J Clin Pharmacol (1997); 44: 175-178
  12. Omeprazole, H2-blockers and polyarthralgia: case control study
    Meier CR, Jick H
    Br Med J (1997); 315: 1283
    PMID: 9390057
    http://bmj.com/cgi/content/full/315/7118/1283  
  13. Drug use and pulmonary death rates in increasingly symptomatic asthmatics in the U.K.
    Meier CR, Jick H
    Thorax (1997); 52: 612-617
    PMID: 9246132
  14. Hormone replacement therapy and risk of venous thromboembolism: population based case-control study
    Perez Gutthann S, Garcia Rodriguez LA, Castellsague Pique J, Duque Oliart A
    Br Med J (1997); 314: 796-800
    PMID: 9081000
    http://bmj.com/cgi/content/full/314/7083/796  
  15. Upper gastrointestinal adverse events and cyclical etidronate
    van Staa TP, Abenhaim L, Cooper C
    Am J Med (1997); 103:467
    PMID: 9428828
  16. Rates of hypoglycemia in users of sulfonylureas
    van Staa TP, Abehaim L, Monette J
    J Clin Epidemiol (1997); 50: 735-745
    PMID: 9250272
  17. 5-Aminosalicylates, sulfasalazine, steroid use, and complications in patients with ulcerative colitis
    Walker AM, Szneke P, Bianchi LA, Field LG, Sutherland LR, Dryer NA
    Am J Gastroenterol (1997); 9: 816-820
    PMID: 9149192
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Research Papers 1996

  1. Sudden unexplained death among subjects with refractory epilepsy
    Derby LE, Tennis P, Jick H
    Epilepsia (1996); 37(10): 931-935
    PMID: 8822690
  2. The use of the General Practice Research Database (GPRD) to examine potential links between antidepressant medication and the incidence of suicide
    Donovan S
    Drug Informat J (1996); 30: 785-792
  3. A cohort study of the ocular safety of anti-ulcer drugs
    Garcia Rodriguez LA, Mannino S, Wallander MA, Lindblom B
    Br J Clin Pharmacol (1996); 42: 213-216
    PMID: 8864320
  4. Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid
    Garcia Rodriguez LA, Stricker BH, Zimmerman HJ
    Arch Int Med (1996); 156: 1327-1332
    PMID: 8651842
  5. Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis
    Henry D, Lim LL-Y, Garcia Rodriguez LA, Perez Gutthann S, Carson JL, Griffin M, Savage R, Logan R, Moride Y, Hawkey C, Hill S, Fries JT
    Br Med J (1996); 312: 1563-1566
    PMID: 8664664
    http://bmj.com/cgi/content/full/312/7046/1563  
  6. The risk of myocardial infarction associated with antihypertensive drug treatment in persons with uncomplicated essential hypertension
    Jick H, Derby LE, Gurewich V, Vasilakis C
    Pharmacotherapy (1996); 16(3): 321-326
    PMID: 8726591
  7. The demand for eating disorder care. An epidemiological study using the General Practice Research Database
    Turnbull SJ, Ward A, Treasure JL, Jick H, Derby LE
    Br J Psychiatry (1996); 169: 705-712
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Research Papers 1995

  1. Care of schizophrenia in general practice: the general practitioner and the patient
    Nazareth I, King M, Davies S
    Br J Gen Pract (1995); 45: 343-347
    PMID: 7612336
  2. Specific therapeutic group age-sex related prescribing units (STAR-PUs): weightings for analysing general practices’ prescribing in England
    Lloyd DCEF, Harris CM, Roberts DJ
    Br Med J (1995); 311: 991-994
    PMID: 7580642
    http://bmj.com/cgi/content/full/311/7011/991  
  3. Hormone replacement therapy: characteristics of users and non-users in a British general practice cohort identified through computerised prescribing records
    Lancaster T, Surman G, Lawrence M, Mant D, Vessey M, Thorogood M, Yudkin P, Daly E
    J Epidemiol Commun Health (1995); 49:389-394
    PMID: 7650462
  4. Antidepressants and suicide
    Jick SS, Dean AD, Jick H
    Br Med J (1995); 310: 215-218
    PMID: 7677826
  5. The risk of sulfasalazine- and mesalazine-associated blood disorders
    Jick H, Myers MW, Dean AD
    Pharmacotherapy (1995); 15(2): 176-181
    PMID: 7624265
  6. Risk of idiopathic cardiovascular death and nonfatal venous thromboembolism in women using oral contraceptive with differing progestagen components
    Jick H, Jick SS, Gurewich V, Myers MW, Vasilakis C
    Lancet (1995); 346: 1589-1593
    PMID: 7500750
  7. A large population-based follow-up study of trimethoprim-sulfamethoxazole, trimethoprim, and cephalexin users for uncommon serious drug toxicity
    Jick H, Derby LE
    Pharmacotherapy (1995); 15(4): 428-432
    PMID: 7479194
  8. Ocular safety of antiulcer drugs (letter)
    Garcia Rodríguez LA, Mannino S, Wallander MA
    Lancet (1995); 345: 1059-1060
    PMID: 7723534
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Research Papers 1994

  1. The quality of information recorded on a UK database of primary care records: A study of hospitalisations due to hypoglycemia and other conditions
    van Staa TP, Abenhaim L
    Pharmacoepidemiology and Drug Safety (1994); 3: 15-21
  2. The use of nitrates, calcium channel blockers and ACE Inhibitors in primary care in the Northern Region: A Pharmacoepidemiological study
    Roberts SJ, Bateman DN
    Br J Clin Pharmacol (1994); 38: 489-497
    PMID: 7888286
  3. A study of the association between hormone replacement therapy, smoking and the occurrence of myocardial infarction in women
    Mann RD, Lis Y, Chukwujindu J, Chanter DO
    J Clin Epidemiol (1994); 47: 307-312
    PMID: 8138842
  4. The VAMP system and the detection of risk. Some examples
    Mann RD
    Pharmacotherapy (1994); 3: 313-319
  5. Flucloxacillin and cholestatic hepatitis (letter)
    Jick H, Derby LE, Dean AD, Henry DA
    Med J Aust (1994); 160: 525
    PMID: 8170433
  6. Acute liver injury associated with nonsteroidal anti-inflammatory drugs and the role of risk factors
    Garcia Rodríguez LA, Williams R, Derby LE, Dean AD, Jick H
    Arch Int Med (1994); 154: 311-316
    PMID: 8297198
  7. Risk of upper gastrointestinal bleeding and perforation associated with individual nonsteroidal anti-inflammatory drugs
    Garcia Rodríguez LA, Jick H
    Lancet (1994); 343: 769-772
    PMID: 7907735
  8. Risk of gynaecomastia associated with cimetidine, omeprazole, and other antiulcer drugs
    Garcia Rodríguez LA, Jick H
    Br Med J (1994); 308: 503-506
    PMID: 8136667
  9. Practice based information systems for monitoring medicines
    Fleming DM
    Pharmaceutical Medicine (1994); 8: 161-176
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Research Papers 1993

  1. Towards accurate prescribing analysis in general practice: accounting for the effects of practice demography
    Sleator DJD
    Br J Gen Pract (1993); 43: 102-106
    PMID: 8323786
  2. Accuracy of diagnosis of psychosis on general practice computer system
    Nazareth I, King M, Haines A, Rangel L, Myers S
    Br Med J (1993); 307: 32-34
    PMID: 8343670
  3. Care of schizophrenia in general practice
    Nazareth I, King M, Haines A, See Tai S, Hall G
    Br Med J (1993); 307:910
    PMID: 8241855
  4. A concurrent cohort study of oral contraceptive users from the VAMP research bank
    Lis Y, Spitzer WO, Mann RD, Cockburn I, Chukwujindu J, Thorogood M, Evans S, Suissa S, Lelorier J
    Pharmacoepidemiology and Drug Safety (1993); 2: 51-53
  5. A follow-up safety study of ciprofloxacin users
    Jick SS, Jick H, Dean AD
    Pharmacotherapy (1993); 13: 461-464
    PMID: 8247912
  6. Nonsteroidal antiinflammatory drugs and certain rare, serious adverse effects. A cohort study
    Jick H, Derby LE, Garcia Rodríguez LA, Jick SS, Dean AD
    Pharmacotherapy (1993); 13:461-464
    PMID: 8321735
  7. Micturin (terodiline hydrochloride), torsades de pointe and other arrhythmias - a study using the VAMP database
    Hall GC, Chukwujindu J, Richardson J, Lis Y, Wild RN
    Pharmacoepidemiology and Drug Safety (1993); 2:127-132
  8. Liver disorders in patients receiving chlorpromazine or isoniazid
    Derby LE, Pérez Gutthann S, Jick H, Dean AD
    Pharmacotherapy (1993); 13: 353-358
    PMID: 8361861
  9. Cholestatic hepatitis associated with flucloxacillin
    Derby LE, Jick H, Henry DA, Dean AD
    Med J Aust (1993); 159: 596-600
    PMID: 8479374
  10. Erythromycin-associated cholestatic hepatitis
    Derby LE, Jick H, Henry DA, Dean AD
    Med J Aust (1993); 158: 600-602
    PMID: 8479375
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Research Papers 1992

  1. Micturin and torsades de pointe-experience of a post-marketing alert
    Wild RN
    Pharmacoepidemiology and Drug Safety (1992); 1: 147-150
  2. Urinary tract infections and estrogen use in older women
    Orlander JD, Jick SS, Dean AD, Jick H
    J Am Geriatr Soc (1992); 40: 817-820
    PMID: 1634725
  3. NSAIDs, quinolones and convulsions: an epidemiologic approach
    Mannino S, Garcia Rodríguez LA, Jick SS
    Post Marketing Surveillance (1992); 6: 119-128
  4. Research implications of computerised primary care
    Mann RD, Hall G, Chukwujindu J
    Post Marketing Surveillance (1992): 5(3): 259-268
  5. Antidepressants and convulsions
    Jick SS, Jick H, Knauss TA, Dean AD
    J Clin Psychopharmacol (1992); 12: 241-245
    PMID: 1527226
  6. Comparison of frequencies of suicidal tendencies among patients receiving fluoxetine, lofepramine, mianserin or trazodone
    Jick H, Ulcickas M, Dean AD
    Pharmacotherapy (1992); 12: 451-454
    PMID: 1492009
  7. Further validation of information recorded on a general practitioner based computerised data resource in the United Kingdom
    Jick H, Terris BZ, Derby LE, Jick SS
    Pharmacoepidemiology and Drug Safety (1992); 1:347-349
  8. Liver disease associated with diclofenac, naproxen and piroxicam
    Jick H, Derby LE, Garcia Rodriguez LA, Jick SS, Dean AD
    Pharmacotherapy (1992); 12: 207-212
    PMID: 1608854
  9. Antidepressant drugs and suicide
    Derby LE, Jick H, Dean AD
    J Clin Psychopharmacol (1992); 12: 235-240
    PMID: 1527225
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Research Papers 1988 - 1991

  1. How common are epileptic seizures in old age?
    Tallis R, Hall G, Craig I, Dean A
    Age and Ageing (1991); 20: 442-448
    PMID: 1776595
  2. Validation of information recorded on general practitioner based computerised data resource in the United Kingdom
    Jick H, Jick SS, Derby LE
    Br Med J (1991); 302: 766-768
    PMID: 2021768
  3. A total audit of preventive procedures in 45 practices caring for 430 000 patients
    Lawrence M, Coulter A, Jones L
    Br Med J (1990); 300: 1501-1503
    PMID: 2372603
  4. A comparison of the risk of hypoglycemia between users of human and animal insulins. Experience in the United Kingdom
    Jick H, Hall GC, Dean AD, Jick SS, Derby LE
    Pharmacotherapy (1990); 10(6): 395-397
    PMID: 2287559
  5. Post marketing surveillance using a computerised general practice data base
    Hall GC, Luscombe DK, Walker SR
    Pharmaceutical Medicine (1988); 2: 345-351
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