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2018
H. Caspard, Steffey, A., Mallory, R. M., and Ambrose, C. S., Evaluation of the safety of live attenuated influenza vaccine (LAIV) in children and adolescents with asthma and high-risk conditions: a population-based prospective cohort study conducted in England with the Clinical Practice Research Datalink, BMJ Open, vol. 8, p. e023118, 2018.
C. I. Bloom, Nissen, F., Douglas, I. J., Smeeth, L., Cullinan, P., and Quint, J. K., Exacerbation risk and characterisation of the UK's asthma population from infants to old age, Thorax, vol. 73, pp. 313-320, 2018.
J. M. Gamble, Chibrikov, E., Midodzi, W. K., Twells, L. K., and Majumdar, S. R., Examining the risk of depression or self-harm associated with incretin-based therapies used to manage hyperglycaemia in patients with type 2 diabetes: a cohort study using the UK Clinical Practice Research Datalink, BMJ Open, vol. 8, p. e023830, 2018.
K. Donegan, Owen, R., Bird, H., Burch, B., Smith, A., and Tregunno, P., Exploring the Potential Routine Use of Electronic Healthcare Record Data to Strengthen Early Signal Assessment in UK Medicines Regulation: Proof-of-Concept Study, Drug Saf, vol. 41, pp. 899-910, 2018.
R. M. Joseph, van Staa, T. P., Lunt, M., Abrahamowicz, M., and Dixon, W. G., Exposure measurement error when assessing current glucocorticoid use using UK primary care electronic prescription data, Pharmacoepidemiol Drug Saf, 2018.
D. R. Morales, Flynn, R., Zhang, J., Trucco, E., Quint, J. K., and Zutis, K., External validation of ADO, DOSE, COTE and CODEX at predicting death in primary care patients with COPD using standard and machine learning approaches, Respir Med, vol. 138, pp. 150-155, 2018.
T. K. Mukhtar, Bankhead, C., Stevens, S., Perera, R., Holt, T. A., Salisbury, C., and Hobbs, F. R., Factors associated with consultation rates in general practice in England, 2013-2014: a cross-sectional study, Br J Gen Pract, vol. 68, pp. e370-e377, 2018.
C. I. Alatorre, Hoogwerf, B. J., Deeg, M. A., Nelson, D. R., Hunter, T. M., Ng, W. T., and Rekhter, M. D., Factors associated with stroke, myocardial infarction, ischemic heart disease, unstable angina, or mortality in patients from real world clinical practice with newly-diagnosed type 2 diabetes and early glycemic control, Curr Med Res Opin, vol. 34, pp. 337-343, 2018.
O. Moussa, Arhi, C., Ziprin, P., Darzi, A., Khan, O., and Purkayastha, S., Fate of the metabolically healthy obese-is this term a misnomer? A study from the Clinical Practice Research Datalink, Int J Obes (Lond), 2018.
M. Iwagami, Tomlinson, L. A., Mansfield, K. E., Douglas, I. J., Smeeth, L., and Nitsch, D., Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study, Br J Clin Pharmacol, vol. 84, pp. 2142-2151, 2018.
R. de Jong, Peeters, P., Burden, A. M., De Bruin, M. L., Haak, H. R., Masclee, A. A. M., de Vries, F., and Janssen-Heijnen, M. L. G., Gastrointestinal cancer incidence in type 2 diabetes mellitus; results from a large population-based cohort study in the UK, Cancer Epidemiol, vol. 54, pp. 104-111, 2018.
J. L. Hong, M. Funk, J., LoCasale, R., Dempster, S. E., Cole, S. R., Webster-Clark, M., Edwards, J. K., and Sturmer, T., Generalizing Randomized Clinical Trial Results: Implementation and Challenges Related to Missing Data in the Target Population, Am J Epidemiol, vol. 187, pp. 817-827, 2018.
A. Douros, Filion, K. B., Yin, H., Yu, O. H., Etminan, M., Udell, J. A., and Azoulay, L., Glucagon-Like Peptide 1 Receptor Agonists and the Risk of Incident Diabetic Retinopathy, Diabetes Care, vol. 41, pp. 2330-2338, 2018.
C. L. Morgan, Qiao, Q., Grandy, S., Johnsson, K., Jenkins-Jones, S., Holden, S., and Currie, C. J., Glucose Control and Weight Change Associated with Treatment with Exenatide Compared with Basal Insulin: A Retrospective Study, Diabetes Ther, vol. 9, pp. 269-283, 2018.
C. Rebordosa, Plana, E., Aguado, J., Thomas, S., Garcia-Gil, E., Perez-Gutthann, S., and Castellsague, J., GOLD assessment of COPD severity in the Clinical Practice Research Datalink (CPRD), Pharmacoepidemiol Drug Saf, 2018.
M. Kerkhof, Tran, T. N., Soriano, J. B., Golam, S., Gibson, D., Hillyer, E. V., and Price, D. B., Healthcare resource use and costs of severe, uncontrolled eosinophilic asthma in the UK general population, Thorax, vol. 73, pp. 116-124, 2018.
H. Otete, Fleming, M. K., West, J., and Orton, E., Healthcare Utilisation, Morbidities and Alcohol Use Monitoring Prior to Alcoholic Psychosis Diagnosis, Alcohol Alcohol, 2018.
S. Vanni, Zattoni, M., Moda, F., Giaccone, G., Tagliavini, F., Haik, S., Deslys, J. P., Zanusso, G., Ironside, J. W., Carmona, M., Ferrer, I., Kovacs, G. G., and Legname, G., Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases, Front Neurosci, vol. 12, p. 8, 2018.
R. Kumar, Hepatitis B virus infection and diabetes mellitus: An adverse relationship A letter in response to Incidence and prevalence of hepatitis B in patients with diabetes mellitus in the UK: A population-based cohort study using the UK Clinical Practice Researc, J Viral Hepat, vol. 25, p. 1401, 2018.
M. Ardissino, Moussa, O., Tang, A., Muttoni, E., Ziprin, P., and Purkayastha, S., Idiopathic intracranial hypertension in the British population with obesity, Acta Neurochir (Wien), 2018.
M. Hickman, Steer, C., Tilling, K., Lim, A. G., Marsden, J., Millar, T., Strang, J., Telfer, M., Vickerman, P., and Macleod, J., The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom, Addiction, vol. 113, pp. 1461-1476, 2018.
E. Martin-Merino, Calderon-Larranaga, A., Hawley, S., Poblador-Plou, B., Llorente-Garcia, A., Petersen, I., and Prieto-Alhambra, D., The impact of different strategies to handle missing data on both precision and bias in a drug safety study: a multidatabase multinational population-based cohort study, Clin Epidemiol, vol. 10, pp. 643-654, 2018.
C. J. Currie, Holden, S. E., Jenkins-Jones, S., Morgan, C. L., Voss, B., Rajpathak, S. N., Alemayehu, B., Peters, J. R., and Engel, S. S., Impact of differing glucose-lowering regimens on the pattern of association between glucose control and survival, Diabetes Obes Metab, vol. 20, pp. 821-830, 2018.
J. Daugherty, Lin, X., Baxter, R., Suruki, R., and Bradford, E., The impact of long-term systemic glucocorticoid use in severe asthma: A UK retrospective cohort analysis, J Asthma, vol. 55, pp. 651-658, 2018.
J. L. Atkins, Delgado, J., Pilling, L. C., Bowman, K., Masoli, J. A. H., Kuchel, G. A., Ferrucci, L., and Melzer, D., Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts, J Gerontol A Biol Sci Med Sci, 2018.
E. Cecil, Bottle, A., Ma, R., Hargreaves, D. S., Wolfe, I., ,, and Saxena, S., Impact of preventive primary care on children's unplanned hospital admissions: a population-based birth cohort study of UK children 2000-2013, BMC Med, vol. 16, p. 151, 2018.
K. C. Chang, Vamos, E. P., Palladino, R., Majeed, A., Lee, J. T., and Millett, C., Impact of the NHS Health Check on inequalities in cardiovascular disease risk: a difference-in-differences matching analysis, J Epidemiol Community Health, 2018.
C. L. Morgan, Inzucchi, S. E., Puelles, J., Jenkins-Jones, S., and Currie, C. J., Impact of treatment with pioglitazone on stroke outcomes: A real-world database analysis, Diabetes Obes Metab, vol. 20, pp. 2140-2147, 2018.
G. L. C. Ferreira, Marano, C., De Moerlooze, L., Guignard, A., Feng, Y., Y. Hahi, E., and Van Staa, T., Incidence and prevalence of hepatitis B in patients with diabetes mellitus in the UK: A population-based cohort study using the UK Clinical Practice Research Datalink, J Viral Hepat, vol. 25, pp. 571-580, 2018.
J. C. Wilson, Sarsour, K., Gale, S., Petho-Schramm, A., Jick, S. S., and Meier, C. R., Incidence and risk of glucocorticoid-associated adverse effects in patients with rheumatoid arthritis, Arthritis Care Res (Hoboken), 2018.
R. Y. van der Velde, Wyers, C. E., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., van de Staa, T. P., and Harvey, N. C., Incidence of subsequent fractures in the UK between 1990 and 2012 among individuals 50 years or older, Osteoporos Int, vol. 29, pp. 2469-2475, 2018.
H. Strongman, Kausar, I., and Maher, T. M., Incidence, Prevalence, and Survival of Patients with Idiopathic Pulmonary Fibrosis in the UK, Adv Ther, vol. 35, pp. 724-736, 2018.
J. G. Royle, Lanyon, P. C., Grainge, M. J., Abhishek, A., and Pearce, F. A., The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink, Clin Rheumatol, vol. 37, pp. 2103-2111, 2018.
R. J. Partington, Muller, S., Helliwell, T., Mallen, C. D., and A. Sultan, A., Incidence, prevalence and treatment burden of polymyalgia rheumatica in the UK over two decades: a population-based study, Ann Rheum Dis, vol. 77, pp. 1750-1756, 2018.
C. Conradt, Guo, D., Miclea, A., Nisslein, T., Ismail, C., Chatamra, K., and Andersohn, F., Increased Prevalence of Polyneuropathy in Parkinson's Disease Patients: An Observational Study, J Parkinsons Dis, vol. 8, pp. 141-144, 2018.
M. Simeonova, de Vries, F., Pouwels, S., Driessen, J. H. M., Leufkens, H. G. M., Cadarette, S. M., and Burden, A. M., Increased risk of all-cause mortality associated with domperidone use in Parkinson's patients: a population-based cohort study in the UK, Br J Clin Pharmacol, vol. 84, pp. 2551-2561, 2018.
E. Richardson, Bedson, J., Chen, Y., Lacey, R., and Dunn, K. M., Increased risk of reproductive dysfunction in women prescribed long-term opioids for musculoskeletal pain: A matched cohort study in the Clinical Practice Research Datalink, Eur J Pain, vol. 22, pp. 1701-1708, 2018.
D. Abrahami, Douros, A., Yin, H., Yu, O. H., Faillie, J. L., Montastruc, F., Platt, R. W., Bouganim, N., and Azoulay, L., Incretin based drugs and risk of cholangiocarcinoma among patients with type 2 diabetes: population based cohort study, Bmj, vol. 363, p. k4880, 2018.
D. Abrahami, Yin, H., Yu, O. H. Y., Pollak, M. N., and Azoulay, L., Incretin-based Drugs and the Incidence of Colorectal Cancer in Patients with Type 2 Diabetes, Epidemiology, vol. 29, pp. 246-253, 2018.
A. Jain, van Hoek, A. J., Walker, J. L., Forbes, H. J., Langan, S. M., Root, A., Smeeth, L., and Thomas, S. L., Inequalities in zoster disease burden: a population-based cohort study to identify social determinants using linked data from the U.K. Clinical Practice Research Datalink, Br J Dermatol, vol. 178, pp. 1324-1330, 2018.
A. Matcho, Ryan, P., Fife, D., Gifkins, D., Knoll, C., and Friedman, A., Inferring pregnancy episodes and outcomes within a network of observational databases, PLoS One, vol. 13, p. e0192033, 2018.
S. R. Markar, Arhi, C., Leusink, A., Vidal-Diez, A., Karthikesalingam, A., Darzi, A., Lagergren, J., and Hanna, G. B., The Influence of Antireflux Surgery on Esophageal Cancer Risk in England: National Population-based Cohort Study, Ann Surg, vol. 268, pp. 861-867, 2018.
V. Prasad, West, J., Sayal, K., and Kendrick, D., Injury among children and young people with and without attention-deficit hyperactivity disorder in the community: The risk of fractures, thermal injuries, and poisonings, Child Care Health Dev, vol. 44, pp. 871-878, 2018.
D. E. Robinson, van Staa, T. P., Dennison, E. M., Cooper, C., and Dixon, W. G., The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: A cohort study, Bone, vol. 117, pp. 83-90, 2018.
E. Badrick, Renehan, I., and Renehan, A. G., Linkage of the UK Clinical Practice Research Datalink with the national cancer registry, Eur J Epidemiol, 2018.
M. Sabido, Thilo, H., and Guido, G., Long-term effectiveness of bisoprolol in patients with angina: A real-world evidence study, Pharmacol Res, vol. 139, pp. 106-112, 2018.
U. Koppe, Nitsch, D., Mansfield, K. E., Mathur, R., Bhaskaran, K., Batterham, R. L., Smeeth, L., and Douglas, I. J., Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink, BMJ Open, vol. 8, p. e020371, 2018.
A. D. Mosholder, Lee, J. Y., Zhou, E. H., Kang, E. M., Ghosh, M., Izem, R., Major, J. M., and Graham, D. J., Long-Term Risk of Acute Myocardial Infarction, Stroke, and Death With Outpatient Use of Clarithromycin: A Retrospective Cohort Study, Am J Epidemiol, vol. 187, pp. 786-792, 2018.
A. Dregan, Ravindrarajah, R., Charlton, J., Ashworth, M., and Molokhia, M., Long-term trends in antithrombotic drug prescriptions among adults aged 80 years and over from primary care: a temporal trends analysis using electronic health records, Ann Epidemiol, vol. 28, pp. 440-446, 2018.
R. M. Joseph, Ray, D. W., Keevil, B., van Staa, T. P., and Dixon, W. G., Low salivary cortisol levels in patients with rheumatoid arthritis exposed to oral glucocorticoids: a cross-sectional study set within UK electronic health records, RMD Open, vol. 4, p. e000700, 2018.