Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
09/07/2024 Sickness absence in the working age population in England before and during the COVID-19 pandemic: a retrospective cohort study using primary care medical certificate data
09/07/2024 Sickness absence in the working age population in England before and during the COVID-19 pandemic: a retrospective cohort study using primary care medical certificate data
19/06/2024 Impact of Mode of Consultation on Antimicrobial Prescribing and Health Complications for Urinary Tract Infections in Primary Care in England
14/06/2024 Changes in Cohort Characteristics and Outcomes During the COVID-19 Pandemic for Three Active Comparator, New User Cohorts
03/06/2024 Changes in healthcare, diagnosis, and treatment of acute and chronic conditions during the COVID-19 pandemic
24/05/2024 Estimating diagnosis incidence and age at diagnosis for growth-affecting conditions in UK children.
21/05/2024 Osteoporotic fractures and kidney injury in people living with an ileostomy
08/05/2024 Safety of Paxlovid Among Patients with Moderate or Severe Hepatic or Renal Impairment: Investigation of Any Safety Events and Events of Special Interest
29/04/2024 Real-world use and effectiveness of COVID-19 vaccines in pregnant women
18/04/2024 Risk of Atherosclerotic Cardiovascular Disease in Early Type 2 Diabetes: A Retrospective Study Using CPRD Aurum Data
18/04/2024 Validation of proposed National Institute of Health and Care Excellence (NICE) indicator for recording of smoking information in patients with severe mental illness (SMI) in primary care data
17/04/2024 Epidemiology of allergic rhinitis in England: A retrospective cohort study in UK primary care data.
17/04/2024 Glucagon-like peptide 1 receptor agonists and the risk of thyroid cancer among patients with type 2 diabetes
16/04/2024 A descriptive study testing new, proposed NICE (National Institute for Health and Care Excellence) indicators on cardiovascular disease (CVD) risk assessments in primary care using general practice data
16/04/2024 Burden of mental health conditions in athletes: A retrospective open cohort study in primary care
16/04/2024 Evaluating the annual learning disability health check for young people in England
16/04/2024 Alport Syndrome Patient Insights using Real-World Evidence: Baseline Characterisation and Treatment Pathways of Patients with Alport Syndrome Across Geographies - Exploring a rare Disease in a multi-database retrospective Cohort Study
15/04/2024 Investigating whether a new NICE (National Institute for Health and Care Excellence) indicator on chronic obstructive pulmonary disease (COPD) annual reviews for those at high risk of hospital admission can be measured using general practice data
15/04/2024 The prevalence, incidence, and mortality of Primary Raynaud's Phenomenon in England, United Kingdom.