Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
09/07/2024	Sickness absence in the working age population in England before and during the COVID-19 pandemic: a retrospective cohort study using primary care medical certificate data
19/06/2024	Impact of Mode of Consultation on Antimicrobial Prescribing and Health Complications for Urinary Tract Infections in Primary Care in England
14/06/2024	Feasibility study to assess outcomes in patients with symptoms of colorectal cancer and negative quantitative faecal immunochemical test
14/06/2024	Changes in Cohort Characteristics and Outcomes During the COVID-19 Pandemic for Three Active Comparator, New User Cohorts
14/06/2024	EXCEED - A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients who Initiated Exenatide as Compared with those who Initiated Other non-Glucagon-Like Peptide 1 Receptor Agonists based Glucose Lowering Drugs
14/06/2024	Effectiveness of glucagon-like peptide 1 receptor agonists to prevent and treat obstructive sleep apnoea
13/06/2024	Prevalence and factors associated with low-allergy formula milk prescription in England
12/06/2024	The association between denosumab use and the risk of atypical femoral fractures in osteoporosis management.
12/06/2024	Evaluation of vaccine effectiveness of maternal pertussis immunisation programme in England
11/06/2024	An observational Cohort study of cardiovascular disease risk in people with Asthma evaluating the role of Leukotriene Receptor Antagonists (LTRAs)
11/06/2024	Post-authorisation Safety Study (PASS) of Rimegepant in Patients with Migraine and History of Cardiovascular Disease in European Countries
11/06/2024	Quantifying, Understanding and Enhancing Relational Continuity of Care (QUERCC)
11/06/2024	Prognosis, management and health inequalities of valvular heart diseases in the UK
11/06/2024	Surgery Waiting Times and Healthcare Resource Use by Body Mass Index in Patients with Osteoarthritis
11/06/2024	Burden of Disease of Herpes Zoster among adults aged 18 years old and older at increased risk due to an immunocompromising or chronic condition in England: a retrospective cohort study
11/06/2024	Trends over time in the use of Advice and Guidance and variation by sociodemographics and type of health condition: repeated cross-sectional and cohort study
11/06/2024	Relationship between Hourly Air Pollution and Ambient Temperature with Daily Hospitalization Rates in Asthma Patients: A Time-Series Analysis
10/06/2024	Understanding the mental health and cardiometabolic diseases outcomes experienced by survivors of knife-related assaults
10/06/2024	Investigating the impact of serum potassium levels on clinical outcomes and treatment management strategies for patients with hyperkalemia in UK clinical settings: an observational study (SPECTRA)
10/06/2024	Post-operative Iron Deficiency Anaemia in patients undergoing potentially curative surgery for Colorectal Cancer. Analysis of the complications, cancer outcomes and all-cause mortality in anaemic and non-anaemic patients.