Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
14/06/2024	Changes in Cohort Characteristics and Outcomes During the COVID-19 Pandemic for Three Active Comparator, New User Cohorts
14/06/2024	EXCEED - A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients who Initiated Exenatide as Compared with those who Initiated Other non-Glucagon-Like Peptide 1 Receptor Agonists based Glucose Lowering Drugs
13/06/2024	Prevalence and factors associated with low-allergy formula milk prescription in England
12/06/2024	Evaluation of vaccine effectiveness of maternal pertussis immunisation programme in England
12/06/2024	The association between denosumab use and the risk of atypical femoral fractures in osteoporosis management.
11/06/2024	Trends over time in the use of Advice and Guidance and variation by sociodemographics and type of health condition: repeated cross-sectional and cohort study
11/06/2024	Relationship between Hourly Air Pollution and Ambient Temperature with Daily Hospitalization Rates in Asthma Patients: A Time-Series Analysis
11/06/2024	Burden of Disease of Herpes Zoster among adults aged 18 years old and older at increased risk due to an immunocompromising or chronic condition in England: a retrospective cohort study
11/06/2024	Prognosis, management and health inequalities of valvular heart diseases in the UK
11/06/2024	Quantifying, Understanding and Enhancing Relational Continuity of Care (QUERCC)
11/06/2024	Post-authorisation Safety Study (PASS) of Rimegepant in Patients with Migraine and History of Cardiovascular Disease in European Countries
11/06/2024	An observational Cohort study of cardiovascular disease risk in people with Asthma evaluating the role of Leukotriene Receptor Antagonists (LTRAs)
11/06/2024	Surgery Waiting Times and Healthcare Resource Use by Body Mass Index in Patients with Osteoarthritis
10/06/2024	Understanding the mental health and cardiometabolic diseases outcomes experienced by survivors of knife-related assaults
10/06/2024	Investigating the impact of serum potassium levels on clinical outcomes and treatment management strategies for patients with hyperkalemia in UK clinical settings: an observational study (SPECTRA)
10/06/2024	Initial uptake of Shingrix vaccine in England: a cohort study
10/06/2024	Post-operative Iron Deficiency Anaemia in patients undergoing potentially curative surgery for Colorectal Cancer. Analysis of the complications, cancer outcomes and all-cause mortality in anaemic and non-anaemic patients.
07/06/2024	Feasibility of using Clinical Practice Research Datalink data to identify people with long term wounds who develop poor mental and psychological wellbeing outcomes
07/06/2024	A cohort study to investigate the use of social prescriptions in England and to describe patterns of healthcare use, prescribing and health outcomes following a social prescribing referral
07/06/2024	Assessing the Availability and Completeness of Alternative Measurements in Routinely Collected Breast Cancer Patient Data: A Feasibility Study