Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
18/12/2015	Descriptive study of patients with haemophilia in the CPRD.
14/12/2015	Trends and factors associated with therapy decisions in newly diagnosed COPD patients in GOLD groups A and B. A non-interventional study using the Clinical Practice Research Datalink (CPRD) database
08/12/2015	An observational evaluation of prescribing of fixed-dose combination inhaled corticosteroid / long-acting beta2-agonist (ICS/LABA): fluticasone propionate / formoterol (FP/FOR) and adverse events in routine primary care at 18-months post launch
08/12/2015	Congenital malformations and maternal use of anti-hypertensive medication in the UK
08/12/2015	Cost Effectiveness of Different Patterns of Monitoring of Cardiovascular Medications in General Practices
08/12/2015	Patterns of prescribing in end of life care using CPRD data.
07/12/2015	Bile duct and gallbladder diseases associated with the use of incretin-based drugs in patients with type 2 diabetes
03/12/2015	Statin Potency and the Risk of Hospitalization for Community-Acquired Pneumonia
03/12/2015	Clinical & Economic Burden of Diabetic Foot Ulcer Care Pathways in the UK
02/12/2015	Use of Finasteride 1mg for Alopecia and the Incidence of Erectile Dysfunction (ED)
02/12/2015	Descriptive study of patients in the CPRD with lysosomal function disorders.
30/11/2015	Association between Use of Beta-blockers or Diuretics and Incident Meniere's Disease
30/11/2015	A descriptive study of LAIV utilization to identify and characterize medication errors due to expired vaccine use in individuals 2-17 years of age in the CPRD
30/11/2015	The association between statin prescribing and the risk of glioma: a matched case-control study
27/11/2015	Prescribing Trends of ADHD Medications in UK Primary Care
26/11/2015	Comparison of the performance of the English NHS Health Checks & Scottish Keep Well programmes
26/11/2015	Near real-time vaccine safety surveillance using the Clinical Practice Research Datalink (CPRD) – a feasibility study
24/11/2015	Utilization of Standard and Target-Specific Oral Anticoagulants among Adults in the United Kingdom with Incident Non-Valvular Atrial Fibrillation
20/11/2015	Risk of MI associated with acute exacerbations of chronic obstructive pulmonary disease (COPD): a self-controlled case series
19/11/2015	Effects of selective serotonin reuptake inhibitors on the risk of mortality in patients with epilepsy: a CALIBER study using linked data