Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
06/10/2015 The association between Huntington's disease and cancer before and after the Huntington's diagnosis - a two-phase study
05/10/2015 An evaluation of the epidemiology and burden of illness of congenital adrenal hyperplasia in the United Kingdom
02/10/2015 Statins for Prevention of Cardiovascular Disease in Older Primary Care UK Patients
02/10/2015 Developing insights into treatment of chronic/diabetic kidney disease (CKD/DKD) using real world data
02/10/2015 Evaluation of the clinical and economic outcomes associated with Bydureon versus basal insulin in people with type 2 diabetes
28/09/2015 Secondary prevention of acute coronary syndrome: comparative effectiveness of recommended vs. less intensive drug combination using Clinical Practice Research Datalink (CPRD). The SCARFACE-CPRD study.
23/09/2015 Evidence for and implications of channeling in the use of nonprescription acetaminophen and ibuprofen in an electronic medical records database
22/09/2015 The risk of fragility fracture in inflammatory arthritis: evidence for the effective and equitable targeting of prevention
18/09/2015 Study to investigate the drug treatment for sialorrhoea in children over the past 10 years.
15/09/2015 Assessing channelling bias and effectiveness in newly marketed glucose-lowering medications - a retrospective cohort study
15/09/2015 Can Continuity Of Primary Care Decrease Unscheduled Secondary Care Use?
14/09/2015 The incidence of Guillain-Barre Syndrome in the United Kingdom from April 2005 to March 2015.
11/09/2015 Healthcare resource utilisation and economic impact among kidney transplant patients during the last year before graft failure in the UK: a retrospective observational study
11/09/2015 Healthcare resource utilisation and economic impact among liver transplant patients during the last year before graft failure in the UK: a retrospective observational study
04/09/2015 Coronary Artery Disease in the Ageing Population of Adults with Congenital Heart Disease
04/09/2015 Time to treatment intensification and associated outcomes among patients with Type 2 diabetes mellitus in the UK
01/09/2015 Medical resource use and costs associated with diabetes complications in the population of diabetes patients receiving insulin therapy in the United Kingdom
28/08/2015 Demographic and clinical characteristics of T2DM patients treated with DPP-4 and SGLT2 inhibitors in the absence of a current clinical guideline - A CPRD Study
28/08/2015 Characteristics of newly diagnosed adults with Type 1 diabetes in the UK and their evolution over the first 5 years
28/08/2015 Cluster Headache Patient Prevalence and Prescribed Treatments in the UK Clinical Practice Research Datalink