Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
30/11/2023 Burden, risk and trends of non-communicable diseases, mortality and hospitalisation among people living with HIV compared to people without HIV
30/11/2023 Clinical characteristics, outcomes and disease trajectories for patients with incident atrial fibrillation
30/11/2023 Exploring the risk of cardioMetabolic complications and describing healthcare resource utilisation in PeOple living With ovERweight and obesity: a non-interventional retrospective longitudinal study in the UK. (EMPOWER)
30/11/2023 Understanding the hip and knee osteoarthritis-arthroplasty pathway and improving Day Case Arthroplasty patient selection
28/11/2023 Gabapentinoids and the risk of severe exacerbation in Chronic Obstructive Pulmonary Disease
28/11/2023 Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
28/11/2023 Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
24/11/2023 The treatment pathway for Atrial Fibrillation from diagnosis to ablation; including the influence of socioeconomic factors on access to ablation in England
23/11/2023 Clinical course, outcomes and risk factors of myocarditis and pericarditis following administration of the Moderna Spikevax COVID-19 vaccine (Elasomeran (mRNA-1273))
23/11/2023 Health outcomes of children with rare or complex diseases and their families: a descriptive longitudinal cohort study
23/11/2023 Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
23/11/2023 Incidence of stroke in patients with epilepsy using anti-seizure medication in England: A retrospective cohort study conducted within the Clinical Practice Research Datalink (CPRD)
22/11/2023 Health inequalities in People with seveRe mental Illnesses: Impact of antipsychOtic tReatments and social Inequalities on long Term phYsical health (PRIORITY).
22/11/2023 Association between COVID-19 and new onset of diabetes
20/11/2023 Exploring inequalities in diagnoses and outcomes of gynaecological cancers in England
17/11/2023 Suicide risk assessment in primary care attenders using big data from general practice
17/11/2023 Clinical Management and Outcomes in Prostate Cancer: Observational, Population-Based Standing Cohort Study in England
17/11/2023 Risk of suicide attempt in patients prescribed leukotriene receptor antagonists (LTRAs) and inhaled corticosteroids (ICS): a self-controlled case series study
15/11/2023 Advantages and Disadvantages using Different Marginal Structural Models Interval Durations in Pharmacoepidemiology
15/11/2023 Prediction risk models for Cardiovascular disease for adults with asthma in England