Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
15/11/2023 Prediction risk models for Cardiovascular disease for adults with asthma in England
15/11/2023 Advantages and Disadvantages using Different Marginal Structural Models Interval Durations in Pharmacoepidemiology
15/11/2023 The association between psoriasis and dementia: a population-based matched cohort study
15/11/2023 The safety of beta-blockers in Chronic Obstructive Pulmonary Disease (COPD): A prevalent new-user cohort study
13/11/2023 Determining clusters of multiple long-term health conditions in patients undergoing surgery
13/11/2023 Defining fibrotic hypertension in electronic healthcare records
13/11/2023 Effect of metformin on the risk of long COVID among overweight and obese individuals: a population-based retrospective cohort study
13/11/2023 Development and validation of cardiovascular and mortality risk scores for haemodialysis patients using statistical and machine learning techniques
09/11/2023 Incidence, prevalence, treatment and natural history of autoimmune diseases in England: a population-based cohort study
07/11/2023 Characterising baseline disease and treatment patterns in alopecia areata
07/11/2023 A comparison of dynamic blood pressure treatment strategies and the risk of cardiovascular events among patients with hypertension: a retrospective cohort study
06/11/2023 The association between timing within the school year and clinical presentations for depression, anxiety, and self-harm
06/11/2023 EXAcerbations of Chronic Obstructive Pulmonary Disease (COPD) and their OutcomeS (EXACOS)-CARBON: estimating the carbon footprint associated with the medical management of individuals living with COPD in England
06/11/2023 Identification of vascular patients at high bleeding risk: validation of the European Socitiety of Cardiology's high bleeding risk criteria
03/11/2023 Investigating prescription cascades and adverse drug reactions of dementia drug treatments
02/11/2023 Drug utilization study in patients with major depressive disorder - a DARWIN EU study
02/11/2023 Prescribing of domperidone among postpartum women: feasibility for a study on off-label prescribing.
02/11/2023 Association between leukotriene receptor antagonist use and reduced risk of epileptic seizure: a self-controlled case series study
02/11/2023 Evaluating connective tissue diseases and vasculitis services in England using patient outcomes: a model for national audit
02/11/2023 Valvular Heart Disease Diagnosis and Treatment Rates in the UK