Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page. 

Date of Approval	Title
11/06/2024	Surgery Waiting Times and Healthcare Resource Use by Body Mass Index in Patients with Osteoarthritis
11/06/2024	Quantifying, Understanding and Enhancing Relational Continuity of Care (QUERCC)
10/06/2024	Post-operative Iron Deficiency Anaemia in patients undergoing potentially curative surgery for Colorectal Cancer. Analysis of the complications, cancer outcomes and all-cause mortality in anaemic and non-anaemic patients.
10/06/2024	Initial uptake of Shingrix vaccine in England: a cohort study
10/06/2024	Understanding the mental health and cardiometabolic diseases outcomes experienced by survivors of knife-related assaults
10/06/2024	Investigating the impact of serum potassium levels on clinical outcomes and treatment management strategies for patients with hyperkalemia in UK clinical settings: an observational study (SPECTRA)
07/06/2024	Feasibility of using Clinical Practice Research Datalink data to identify people with long term wounds who develop poor mental and psychological wellbeing outcomes
07/06/2024	A cohort study to investigate the use of social prescriptions in England and to describe patterns of healthcare use, prescribing and health outcomes following a social prescribing referral
07/06/2024	Examining the epidemiology and mortality of people with psoriasis
07/06/2024	Assessing the Availability and Completeness of Alternative Measurements in Routinely Collected Breast Cancer Patient Data: A Feasibility Study
04/06/2024	Trends and Patterns in Multimorbidity in Children and Young People
03/06/2024	Changes in healthcare, diagnosis, and treatment of acute and chronic conditions during the COVID-19 pandemic
03/06/2024	Identifying early indicators of prostate cancer progression from longitudinal clinical data.
31/05/2024	Association between hypertensive disorders of pregnancy and subsequent development of arrhythmias: A retrospective cohort study
24/05/2024	Evaluating the risks and benefits of renin-angiotensin system inhibitor treatment in chronic kidney disease using prediction under intervention models
24/05/2024	Estimating diagnosis incidence and age at diagnosis for growth-affecting conditions in UK children.
21/05/2024	Osteoporotic fractures and kidney injury in people living with an ileostomy
20/05/2024	Isotretinoin exposure during pregnancy
15/05/2024	Incidence and Prevalence of Ectopic Pregnancy
15/05/2024	Health and Labor Market Impacts of Hormone Replacement Therapy: A Descriptive Retrospective Analysis of Hormone Replacement Therapy Prescriptions Using UK Primary Care Data and Supplementary Labour Force Survey and Understanding Society Survey Data