Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after RDG approval. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

Date of Approval Sort ascending Title
29/08/2023 Association between propensity to prescribe antibiotics for common infections in primary care and adverse outcomes
29/08/2023 Risk of Osteonecrosis of the Jaw in Female Users of Osteoporosis Treatments
22/08/2023 Global COVID Vaccine Safety (GCoVS) Project Investigating COVID-19 Vaccination and Adverse Events, including Myocarditis, Pericarditis, Guillain-Barre Syndrome and Vaccine Induced Thrombosis and Thrombocytopenia: A Self-controlled case series study.
22/08/2023 Characterisation of Medication Utilisation and Clusters Prior to, During and After Pregnancy: A Population-Based Descriptive Study
22/08/2023 Primary care for care home residents: Changes over time before and through the COVID-19 pandemic
22/08/2023 Changes in survival, and causes of death in people with idiopathic pulmonary fibrosis in England, 2010 to 2022
21/08/2023 Feasibility Study to Assess the Recording of Endocrine Therapy Use and Induced Vasomotor Symptoms among Women with Breast Cancer in the UK
16/08/2023 Understanding and addressing socio-economic inequality within the quality and safety of care and outcomes for people living with dementia.
15/08/2023 Chronic pain and opioid prescribing in the local health economy: the trends in prevalence and incidence and associated healthcare resource utilisation
15/08/2023 Feasibility and assessment of the association between opioid use and the development of diverticulitis
14/08/2023 Vascular disease and cancer: cohort studies of adult cancer populations and outcomes
10/08/2023 Enhancing Autism Spectrum Disorder (ASD) Research in the United Kingdom: Prevalence Estimation and Comparative Assessment of Conventional Regression and Machine Learning Models for ASD Risk Prediction
09/08/2023 The association between hyperglycaemia and hypertension during pregnancy and their impact on maternal health and birth outcomes- a retrospective cohort study in the CPRD database
09/08/2023 Adverse health outcomes among people with atopic eczema: a consistent application of cohort study design to multiple outcomes
09/08/2023 A treat to target approach for obesity management: exploring potential treatment targets
09/08/2023 The risk of adverse psychiatric and somatic outcomes with gabapentinoid use: a UK population-based study using electronic health records
08/08/2023 The association between prescriptions for inhaled corticosteroids, pneumonia and exacerbations in people with asthma and Chronic obstructive pulmonary disease
04/08/2023 Risk of suicide events with discontinuation of antidepressant treatment in patients with major depressive disorder.
04/08/2023 The efficacy and safety of concomitant treatment with candesartan and indapamide in patients with essential arterial hypertension: Outcomes in real world practice
03/08/2023 Co-prescribing of endothelin receptor antagonists (ERAs) and phosphodiesterate-5 inhibitors (PDE-5is) in pulmonary arterial hypertension (PAH) - a DARWIN EU study