| 2025 |
Epidemiology of gender dysphoria and gender incongruence in children and young people attending primary care practices in England: retrospective cohort study
10.1136/archdischild-2024-327992
Authors: S. Jarvis, L. Fraser, T. Langton, C. Hewitt, T. Doran |
| 2025 |
Estimating the burden of underdiagnosis within England: A modelling study of linked primary care data
10.1371/journal.pone.0313877
Authors: O. Anosova, A. Head, B. Collins, A. Alexiou, K. Darras, M. Sutton, R. Cookson, L. Anselmi, M. O'Flaherty, B. Barr, C. Kypridemos |
| 2025 |
Causes of death in patients with atrial fibrillation in the UK: a nationwide electronic health record study
10.1093/ehjopen/oeae103
Authors: Y. Lai, H. Yoshimura, N. Zakkak, E. Marijon, A. Chahal, G. Lip, F. Schmidt, R. Providencia |
| 2025 |
The association between fibrotic diseases and treatment resistant hypertension in England
10.1093/eurjpc/zwaf068
Authors: G. Massen, P. Stone, R. Jenkins, R. Allen, L. Wain, I. Stewart, U. Tayal, J. Quint |
| 2025 |
Continuity and locum use for acute consultations: observational study of subsequent workload
10.3399/bjgp.2024.0312
Authors: H. Kajaria-Montag, S. Scholtes, D. Gray, K. Sidaway-Lee, M. Freeman, P. Evans |
| 2025 |
A UK population-based case-control study of blood tests before cancer diagnosis in patients with non-specific abdominal symptoms
10.1038/s41416-024-02936-9
Authors: M. Rafiq, B. White, M. Barclay, G. Abel, C. Renzi, G. Lyratzopoulos |
| 2025 |
Prevalence and outcomes of patients taking oral corticosteroids for over 1 month undergoing major surgery in England 2010-2020
10.1111/anae.16532
Authors: J. Harris, G. Russell, B. Reeves, B. Gibbison |
| 2025 |
Potential interactions between digoxin and direct oral anticoagulants: application of cohort & novel case-crossover designs
10.1016/j.jclinepi.2025.111709
Authors: A. Wong, C. Warren-Gash, K. Bhaskaran, C. Leyrat, A. Banerjee, L. Smeeth, I. Douglas |
| 2025 |
Glucagon-like peptide-1 receptor agonists and risk of suicidality among patients with type 2 diabetes: active comparator, new user cohort study
10.1136/bmj-2024-080679
Authors: S. Shapiro, H. Yin, O. H. Y. Yu, S. Rej, S. Suissa, L. Azoulay |
| 2025 |
Stroke incidence in heart failure and atrial fibrillation: population cohort study
10.3399/bjgp.2024.0470
Authors: N. Jones, M. Smith, S. Lay-Flurrie, Y. Yang, F. Hobbs, C. Taylor |
| 2025 |
Adverse childhood experiences in firstborns and mental health risk and health-care use in siblings: a population-based birth cohort study of half a million children in England
10.1016/s2468-2667(24)00301-3
Authors: S. Syed, L. Howe, R. Lacey, J. Deighton, Qummer Arfeen, G. Feder, R. Gilbert |
| 2025 |
Achievement of HbA1c and weight targets in adults with type 2 diabetes on once weekly injectable glucagon-like peptide-1 receptor agonist therapy in UK primary care: A retrospective, real-world study
10.1111/dom.16201
Authors: K. Gulati, K. Wijndaele, J. Webb, L. von Arx, M. Seif, T. Jennison, A. Geneidat, R. Wild, R. Wood, K. Khunti |
| 2025 |
Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK
10.2147/jaa.s452747
Authors: I. Gouia, F. Joulain, Y. Zhang, C. Morgan, A. Khan |
| 2025 |
The impact of COVID vaccination on incidence of long COVID and healthcare resource utilisation in a primary care cohort in England, 2021-2022
10.1186/s12879-024-10097-6
Authors: J. Yang, K. Rai, T. Alfred, L. Massey, O. Massey, L. McGrath, K. Andersen, T. Tritton, C. Tsang, R. Butfield, C. Reynard, D. Mendes, J. Nguyen |
| 2025 |
Identifying children who develop severe chronic kidney disease using primary care records
10.1371/journal.pone.0314084
Authors: L. Plumb, M. Sinha, T. Jones, M. Redaniel, M. Ridd, A. Owen-Smith, F. Caskey, Y. Ben-Shlomo |
| 2025 |
Burden of vascular risk factors by age, sex, ethnicity and deprivation in young adults with and without newly diagnosed type 2 diabetes
10.1016/j.diabres.2025.112002
Authors: J. Goldney, M. Barker, J. Sargeant, E. Daynes, D. Papamargaritis, S. Shabnam, L. Goff, K. Khunti, J. Henson, M. Davies, F. Zaccardi |
| 2025 |
The impact of polypharmacy on health outcomes in the aged: A retrospective cohort study
10.1371/journal.pone.0317907
Authors: I. Boateng, C. Pascual, P. Grassby, Z. Asghar, K. Ibrahim |
| 2025 |
Maternal postpartum six-week check and short-term health outcomes for women with hypertensive disorders in pregnancy: An observational study using the Clinical Practice Research Datalink (CPRD)
10.1111/aogs.15068
Authors: R. Ramakrishnan, D. Korb, Y. Li, M. Knight, C. Carson |
| 2025 |
Prevalence and patient characteristics associated with cardiovascular disease risk factor screening in UK primary care for people with severe mental illness: an electronic healthcare record study
10.1136/bmjment-2024-301409
Authors: N. Launders, C. Jackson, J. Hayes, A. John, R. Stewart, M. Iveson, E. Bramon, B. Guthrie, S. Mercer, D. Osborn |
| 2025 |
Incidence trends in ischaemic and non-ischaemic heart failure in people with and without type 2 diabetes, 2000-2019: An observational study in England
10.1016/j.diabres.2024.111980
Authors: K. Panchal, C. Lawson, S. Shabnam, K. Khunti, F. Zaccardi |
| 2025 |
Hearing loss and risk of major osteoporotic fracture: a population-based cohort study in the United Kingdom
10.1007/s11657-024-01484-2
Authors: S. Khalid, D. Alhambra, S. Hasheminasab, Y. Vinogradova, N. Qureshi, M. Ratzinger, V. Brunetti, A. Salas, L. Canals |
| 2025 |
Disease burden, healthcare resource utilisation, and treatment patterns in patients with newly diagnosed myasthenia gravis in England: A retrospective cohort study
10.1177/22143602241308194
Authors: K. Bonar, N. Boudiaf, P. Zaremba, T. Tarancón, J. Zhou, S. Jacob |
| 2025 |
Population-Based Validation Results From the Drug Repurposing for Effective Alzheimer's Medicines (DREAM) Study
10.1002/cpt.3583
Authors: R. Desai, V. Varma, M. Mahesri, S. Lee, A. Freedman, T. Gerhard, J. Segal, S. Vine, M. Ritchey, D. Horton, M. Thambisetty |
| 2025 |
Diabetes complications in people with alcohol use disorder and type 2 diabetes
10.3399/bjgpo.2024.0133
Authors: S. Cook, S. Saxena, R. Mathur, T. Beaney, S. Gnani, A. Neves, A. Maini, R. Parekh, K. Walters, D. Osborn, J. Quint |
| 2025 |
The Clinical Practice Research Datalink (CPRD) Mother-Baby Links: A Data Resource Profile
10.1002/pds.70091
Authors: S. Coton, S. Welburn, R. Williams, J. Campbell |
| 2025 |
Benzodiazepine and z-drug prescribing in critical care survivors and the risk of rehospitalisation or death due to falls/trauma and due to any cause: a retrospective matched cohort study using the UK Clinical Practice Research Datalink
10.1007/s00134-024-07762-4
Authors: E. Mansi, C. Rentsch, R. Bourne, A. Jeffery, B. Guthrie, N. Lone |
| 2025 |
Potential interactions between antimicrobials and direct oral anticoagulants: Population-based cohort and case-crossover study
10.1016/j.hrthm.2025.01.007
Authors: A. Wong, C. Warren-Gash, K. Bhaskaran, C. Leyrat, A. Banerjee, L. Smeeth, I. Douglas |
| 2025 |
Monitoring for 5-aminosalicylate nephrotoxicity in adults with inflammatory bowel disease: prognostic model development and validation using data from the Clinical Practice Research Datalink
10.1136/bmjgast-2024-001627
Authors: A. Abhishek, G. Nakafero, T. Card, M. Taal, M. Grainge, G. Aithal, C. Mallen, M. Stevenson, R. Riley |
| 2025 |
Greenhouse gas emissions associated with severe asthma care in the United Kingdom
10.1016/j.jaip.2025.02.012
Authors: A. Wilkinson, M. Khezrian, L. Heaney, S. Patel, J. Quint, H. Rupani, E. Rapsomaniki, K. Rhodes, A. Menzies-Gow, T. Tran |
| 2025 |
General practice antibiotic prescriptions attributable to respiratory syncytial virus by age and antibiotic class: an ecological analysis of the English population
10.1093/jac/dkaf043
Authors: L. Miller, T. Beaney, R. Hope, M. Cunningham, J. Robotham, K. Pouwels, C. Costelloe |
| 2025 |
Using Quantitative Bias Analysis to Adjust for Misclassification of COVID-19 Outcomes: An Applied Example of Inhaled Corticosteroids and COVID-19 Outcomes
10.1002/pds.70086
Authors: M. Bokern, C. Rentsch, J. Quint, J. Hunnicutt, I. Douglas, A. Schultze |
| 2025 |
Psoriasis and dementia: A population-based matched cohort study of adults in England
10.1002/acn3.52283
Authors: J. Matthewman, K. Mansfield, S. Cadogan, K. Abuabara, C. Smith, K. Bhaskaran, S. Langan, C. Warren-Gash |
| 2025 |
Association between diabetes self-management education attendance, hospital admissions and mortality in type 2 diabetes: A cohort analysis protocol
10.1111/dom.16257
Authors: G. Lewis, D. Hughes, G. Irving, J. Wilding, K. Hardy |
| 2025 |
Safety and effectiveness of anticoagulation therapy in older people with atrial fibrillation during exposed and unexposed treatment periods
10.1136/heartjnl-2024-324763
Authors: A. Mitchell, M. Watson, T. Welsh, A. McGrogan |
| 2025 |
Life course trajectories of maternal cardiovascular disease risk factors by obstetric history: a UK cohort study using electronic health records
10.1186/s12916-025-03937-y
Authors: K. Birnie, L. Howe, T. Jones, P. Madley-Dowd, F. Martin, H. Forbes, M. Redaniel, R. Cornish, M. Magnus, N. Davies, K. Tilling, A. Hughes, D. Lawlor, A. Fraser |
| 2025 |
Treatment patterns, outcomes and healthcare resource utilization of obstructive hypertrophic cardiomyopathy in England
10.1002/ehf2.15213
Authors: F. Osman, C. Zema, M. Hurst, B. Sandler, F. Brellier, O. Utuama, O. Kirichek, J. Houghton, T. Lemmer, M. Esteban |
| 2025 |
Validation of Clinical Practice Research Datalink (CPRD) Aurum Mother-Baby Link
10.1002/pds.5860
Authors: C. Vasilakis-Scaramozza, R. Persson, G. Kafatos, D. Neasham, K. Hagberg, S. Jick |
| 2025 |
Association between use of sodium-glucose co-transporter-2 inhibitor and the risk of incident dementia: a population-based cohort study
10.1136/bmjdrc-2024-004541
Authors: Z. Abdullah, Y. Cui, R. Platt, C. Renoux, L. Azoulay, C. Xia, O. H. Y. Yu |
| 2025 |
A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data
10.1016/j.ebiom.2025.105584
Authors: O. Murrin, N. Mounier, B. Voller, L. Tata, C. Gallego-Moll, A. Roso-Llorach, L. Carrasco-Ribelles, C. Fox, L. Allan, R. Woodward, X. Liang, J. Valderas, S. Khalid, F. Dudbridge, S. Lamb, M. Mancini, L. Farmer, K. Boddy, J. Bowden, D. Melzer, T. Frayling, J. Masoli, L. Pilling, C. Violán, J. Delgado |
| 2025 |
Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors and the Prevention of Cirrhosis Among Patients With Type 2 Diabetes
10.2337/dc24-1903
Authors: R. Pradhan, H. Yin, S. Lu, G. Sebastiani, O. Yu, S. Suissa, L. Azoulay |
| 2025 |
Comparative cardiometabolic safety and effectiveness of aripiprazole in people with severe mental illness: A target trial emulation
10.1371/journal.pmed.1004520
Authors: A. Richards-Belle, N. Launders, S. Hardoon, A. Richards, K. Man, N. Davies, E. Bramon, J. Hayes, D. Osborn |
| 2025 |
Gestational diabetes mellitus and subsequent cardiovascular disease in a period of rising diagnoses: Cohort study
10.1111/aogs.15022
Authors: A. Mehrabadi, Y. Yu, S. Grandi, R. Platt, K. Filion |
| 2025 |
Patterns of analgesic utilisation among people with knee osteoarthritis: a cohort study using UK primary care data
10.1080/20523211.2025.2455067
Authors: A. Taqi, S. Gran, R. Knaggs |
| 2025 |
Addressing uncertainty in identifying pregnancies in the English CPRD GOLD Pregnancy Register: a methodological study using a worked example
10.23889/ijpds.v10i1.2471
Authors: Y. Li, J. Kurinczuk, F. Alderdice, M. Quigley, O. Rivero-Arias, J. Sanders, S. Kenyon, D. Siassakos, N. Parekh, S. De Almeida, C. Carson |
| 2025 |
Cardiovascular disease morbidity is associated with social deprivation in subjects with familial hypercholesterolaemia (FH): A retrospective cohort study of individuals with FH in UK primary care and the UK Simon Broome register
10.1016/j.atherosclerosis.2025.119142
Authors: B. Iyen, N. Qureshi, J. Kai, N. Capps, P. Durrington, J. Cegla, H. Soran, J. Schofield, H. Neil, S. Humphries |
| 2024 |
The risk of acute infections in new users of antidepressants: An observational cohort study
10.1016/j.jad.2024.03.002
Authors: N. Aebi, C. Meier, S. Jick, U. Lang, J. Spoendlin |
| 2024 |
Clostridioides difficile infections, recurrences, and clinical outcomes in real-world settings from 2015 to 2019: The RECUR England study
10.1016/j.ijid.2024.01.002
Authors: S. Ghosh, A. Antunes, H. Rinta-Kokko, E. Chaparova, S. Lay-Flurrie, A. Tricotel, F. Andersson |
| 2024 |
Ethnic differences in depression and anxiety among adults with atopic eczema: Population-based matched cohort studies within UK primary care
10.1002/clt2.12348
Authors: E. Adesanya, A. Henderson, J. Hayes, A. Lewin, R. Mathur, A. Mulick, C. Morton, C. Smith, S. Langan, K. Mansfield |
| 2024 |
Oral prednisolone and warfarin and risk of oesophageal cancer: A case-control study
10.1016/j.canep.2024.102552
Authors: C. Cardwell, R. McDowell, C. Hughes, J. Busby, P. Murchie |
| 2024 |
Sodium-glucose cotransporter-2 inhibitors and the risk of atrial fibrillation in patients with type 2 diabetes: a population-based cohort study
10.1093/ehjcvp/pvae022
Authors: T. Eroglu, R. Coronel, P. Souverein |
