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UK data driving real-world evidence
Bibliography
Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 4 March 2021) and papers are listed below and in the PDF below.
If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.
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(PDF, 3MB, 220 pages)This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website.
“The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations”, Pharmacoepidemiol Drug Saf, 2019.
, “Ankylosing spondylitis and risk of ischaemic heart disease: a population-based cohort study”, Ann Rheum Dis, vol. 75, pp. 203-9, 2016.
, “Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations, and methodological implications”, Eur J Clin Pharmacol, vol. 70, pp. 849-57, 2014.
, “Anti-osteoporosis drug prescribing after hip fracture in the UK: 2000-2010”, Osteoporos Int, vol. 26, pp. 1919-28, 2015.
, , , “Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD)”, Copd, pp. 1-8, 2019.
, “Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality”, Pharmacoepidemiol Drug Saf, vol. 27, pp. 1191-1199, 2018.
, “Bone fracture risk is not associated with the use of glucagon-like peptide-1 receptor agonists: a population-based cohort analysis”, Calcif Tissue Int, vol. 97, pp. 104-12, 2015.
, “Bridging differences in outcomes of pharmacoepidemiological studies: design and first results of the PROTECT project”, Curr Clin Pharmacol, vol. 9, pp. 130-8, 2014.
, “Cancer recording in patients with and without type 2 diabetes in the Clinical Practice Research Datalink primary care data and linked hospital admission data: a cohort study”, BMJ Open, vol. 8, p. e020827, 2018.
, “Cancer risk among insulin users: comparing analogues with human insulin in the CARING five-country cohort study”, Diabetologia, vol. 60, pp. 1691-1703, 2017.
, “Cardiovascular safety of vildagliptin in patients with type 2 diabetes: A European multi-database, non-interventional post-authorization safety study”, Diabetes Obes Metab, vol. 19, pp. 1473-1478, 2017.
, “Causes of death in patients with multiple sclerosis and matched referent subjects: a population-based cohort study”, Eur J Neurol, vol. 19, pp. 1007-14, 2012.
, “Chlamydia trachomatis and the Risk of Pelvic Inflammatory Disease, Ectopic Pregnancy, and Female Infertility: A Retrospective Cohort Study Among Primary Care Patients”, Clinical Infectious Diseases, 2019.
, “Comparability of the age and sex distribution of the UK Clinical Practice Research Datalink and the total Dutch population”, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1460-1464, 2016.
, “Concomitant use of ibuprofen and paracetamol and the risk of major clinical safety outcomes”, Br J Clin Pharmacol, vol. 70, pp. 429-38, 2010.
, “Concomitant use of oral glucocorticoids and proton pump inhibitors and risk of osteoporotic fractures among patients with rheumatoid arthritis: a population-based cohort study”, Ann Rheum Dis, 2020.
, “C-reactive protein as a biomarker of response to inhaled corticosteroids among patients with COPD”, Pulm Pharmacol Ther, p. 101870, 2019.
, “The effect of body mass index on the risk of post-operative complications during the 6 months following total hip replacement or total knee replacement surgery”, Osteoarthritis Cartilage, vol. 22, pp. 918-27, 2014.
, “Elevated risk of clinical fractures and associated risk factors in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom”, Osteoporos Int, vol. 25, pp. 1275-83, 2014.
, “The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study”, Ann Rheum Dis, vol. 74, pp. 1373-8, 2015.
, “Epidemiology of fractures in the United Kingdom 1988-2012: Variation with age, sex, geography, ethnicity and socioeconomic status”, Bone, vol. 87, pp. 19-26, 2016.
, “The epidemiology of mortality after fracture in England: variation by age, sex, time, geographic location, and ethnicity”, Osteoporos Int, vol. 28, pp. 161-168, 2017.
, “Ethnic and geographic variations in the epidemiology of childhood fractures in the United Kingdom”, Bone, vol. 85, pp. 9-14, 2016.
, “Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project”, Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 56-65, 2016.
, “Five-year fracture risk estimation in patients with Parkinson's disease”, Bone, vol. 56, pp. 266-70, 2013.
, “Fracture rate in patients with myasthenia gravis: the general practice research database”, Osteoporos Int, vol. 24, pp. 467-76, 2013.
, “Fracture risk before and after total hip replacement in patients with osteoarthritis: potential benefits of bisphosphonate use”, Arthritis Rheum, vol. 63, pp. 992-1001, 2011.
, “Fracture risk in patients receiving acid-suppressant medication alone and in combination with bisphosphonates”, Osteoporos Int, vol. 20, pp. 1989-98, 2009.
, “Fracture risk with intermittent high-dose oral glucocorticoid therapy”, Arthritis Rheum, vol. 56, pp. 208-14, 2007.
, “Gastrointestinal cancer incidence in type 2 diabetes mellitus; results from a large population-based cohort study in the UK”, Cancer Epidemiol, vol. 54, pp. 104-111, 2018.
, “High risk of drug-induced microscopic colitis with concomitant use of NSAIDs and proton pump inhibitors”, Aliment Pharmacol Ther, vol. 43, pp. 1004-13, 2016.
, “Identification of antithrombotic drugs related to total joint replacement using anonymised free-text notes: a search strategy in the Clinical Practice Research Datalink”, BMJ Open, vol. 5, p. e009017, 2015.
, “The Impact of the Choice of Data Source in Record Linkage Studies Estimating Mortality in Venous Thromboembolism”, PLoS One, vol. 11, p. e0148349, 2016.
, “Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink”, Diabetes Res Clin Pract, vol. 148, pp. 240-248, 2019.
, “Impact of varying outcomes and definitions of suicidality on the associations of antiepileptic drugs and suicidality: comparisons from UK Clinical Practice Research Datalink (CPRD) and Danish national registries (DNR)”, Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 142-55, 2016.
, “Incidence of subsequent fractures in the UK between 1990 and 2012 among individuals 50 years or older”, Osteoporos Int, vol. 29, pp. 2469-2475, 2018.
, “Increased risk of all-cause mortality associated with domperidone use in Parkinson's patients: a population-based cohort study in the UK”, Br J Clin Pharmacol, vol. 84, pp. 2551-2561, 2018.
, “Individuals With Type 2 Diabetes Mellitus Are at an Increased Risk of Gout But This Is Not Due to Diabetes: A Population-Based Cohort Study”, Medicine (Baltimore), vol. 94, p. e1358, 2015.
, “Influence of metformin intake on the risk of bladder cancer in type 2 diabetes patients”, Br J Clin Pharmacol, vol. 80, pp. 1464-72, 2015.
, “Insulin glargine use and breast cancer risk: Associations with cumulative exposure”, Acta Oncol, vol. 55, pp. 851-8, 2016.
, “Lithium use and the risk of fractures”, Bone, vol. 40, pp. 1252-8, 2007.
, “Long-acting {beta}2-agonists in adult asthma and the pattern of risk of death and severe asthma outcomes: a study using the GPRD”, Eur Respir J, vol. 36, pp. 494-502, 2010.
, “Long-term use of dipeptidyl peptidase-4 inhibitors and risk of fracture: A retrospective population-based cohort study”, Diabetes Obes Metab, vol. 19, pp. 421-428, 2017.
, “Medication adherence among gout patients initiated allopurinol: a retrospective cohort study in the Clinical Practice Research Datalink (CPRD)”, Rheumatology (Oxford), vol. 57, pp. 1641-1650, 2018.
, “Mortality, causes of death and influence of medication use in patients with systemic lupus erythematosus vs matched controls”, Rheumatology (Oxford), 2020.
, “Mortality in British hip fracture patients, 2000-2010: a population-based retrospective cohort study”, Bone, vol. 66, pp. 171-7, 2014.
, , “Obstructive sleep apnea and the risk of gout: a population-based case-control study”, Arthritis Res Ther, vol. 22, p. 92, 2020.
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