Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 October 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
A. Root, Brown, J. P., Forbes, H. J., Bhaskaran, K., Hayes, J., Smeeth, L., and Douglas, I. J., “Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression”, JAMA Pediatr, 2019.
Y. Schonmann, Mansfield, K. E., Hayes, J. F., Abuabara, K., Roberts, A., Smeeth, L., and Langan, S. M., “Atopic eczema in adulthood and risk of depression and anxiety: a population-based cohort study”, J Allergy Clin Immunol Pract, 2019.
H. Strongman, Brown, A., Smeeth, L., and Bhaskaran, K., “Body mass index and Hodgkin's lymphoma: UK population-based cohort study of 5.8 million individuals”, Br J Cancer, 2019.
F. Nissen, Douglas, I. J., Mullerova, H., Pearce, N., Bloom, C. I., Smeeth, L., and Quint, J. K., “Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink)”, J Asthma Allergy, vol. 12, pp. 7-19, 2019.
S. J. Sinnott, Smeeth, L., Williamson, E., Perel, P., Nitsch, D., Tomlinson, L. A., and Douglas, I. J., “The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data”, Pharmacoepidemiol Drug Saf, 2019.
C. I. Bloom, Douglas, I., Olney, J., D'Ancona, G., Smeeth, L., and Quint, J. K., “Cost saving of switching to equivalent inhalers and its effect on health outcomes”, Thorax, 2019.
E. Herrett, Gadd, S., Jackson, R., Bhaskaran, K., Williamson, E., Van Staa, T., Sofat, R., Timmis, A., and Smeeth, L., “Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study”, Lancet, 2019.
M. Pikoula, Quint, J. K., Nissen, F., Hemingway, H., Smeeth, L., and Denaxas, S., “Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records”, BMC Med Inform Decis Mak, vol. 19, p. 86, 2019.
H. Strongman, Gadd, S., Matthews, A., Mansfield, K. E., Stanway, S., Lyon, A. R., dos-Santos-Silva, I., Smeeth, L., and Bhaskaran, K., “Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic health records databases”, Lancet, 2019.
R. E. Farmer, Ford, D., Mathur, R., Chaturvedi, N., Kaplan, R., Smeeth, L., and Bhaskaran, K., “Metformin use and risk of cancer in patients with type 2 diabetes: a cohort study of primary care records using inverse probability weighting of marginal structural models”, Int J Epidemiol, 2019.
C. Minassian, Williams, R., Meeraus, W. H., Smeeth, L., Campbell, O. M. R., and Thomas, S. L., “Methods to generate and validate a Pregnancy Register in the UK Clinical Practice Research Datalink primary care database”, Pharmacoepidemiol Drug Saf, vol. 28, pp. 923-933, 2019.
C. I. Bloom, Ricciardi, F., Smeeth, L., Stone, P., and Quint, J. K., “Predicting COPD 1-year mortality using prognostic predictors routinely measured in primary care”, BMC Med, vol. 17, p. 73, 2019.
2018
K. E. Mansfield, Douglas, I. J., Nitsch, D., Thomas, S. L., Smeeth, L., and Tomlinson, L. A., “Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis”, Clin Epidemiol, vol. 10, pp. 187-202, 2018.
K. Bhaskaran, dos-Santos-Silva, I., Leon, D. A., Douglas, I. J., and Smeeth, L., “Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3.6 million adults in the UK”, Lancet Diabetes Endocrinol, vol. 6, pp. 944-953, 2018.
J. Wilding, Godec, T., Khunti, K., Pocock, S., Fox, R., Smeeth, L., Clauson, P., Fenici, P., Hammar, N., and Medina, J., “Changes in HbA1c and weight, and treatment persistence, over the 18 months following initiation of second-line therapy in patients with type 2 diabetes: results from the United Kingdom Clinical Practice Research Datalink”, BMC Med, vol. 16, p. 116, 2018.
S. Wilkinson, Douglas, I., Stirnadel-Farrant, H., Fogarty, D., Pokrajac, A., Smeeth, L., and Tomlinson, L., “Changing use of antidiabetic drugs in the UK: trends in prescribing 2000-2017”, BMJ Open, vol. 8, p. e022768, 2018.
M. Iwagami, Caplin, B., Smeeth, L., Tomlinson, L. A., and Nitsch, D., “Chronic kidney disease and cause-specific hospitalisation: a matched cohort study using primary and secondary care patient data”, Br J Gen Pract, vol. 68, pp. e512-e523, 2018.
A. D. Morgan, Rothnie, K. J., Bhaskaran, K., Smeeth, L., and Quint, J. K., “Chronic obstructive pulmonary disease and the risk of 12 cardiovascular diseases: a population-based study using UK primary care data”, Thorax, vol. 73, pp. 877-879, 2018.
F. Nissen, Morales, D. R., Mullerova, H., Smeeth, L., Douglas, I. J., and Quint, J. K., “Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care”, Br J Gen Pract, vol. 68, pp. e775-e782, 2018.
C. I. Bloom, Nissen, F., Douglas, I. J., Smeeth, L., Cullinan, P., and Quint, J. K., “Exacerbation risk and characterisation of the UK's asthma population from infants to old age”, Thorax, vol. 73, pp. 313-320, 2018.
M. Iwagami, Tomlinson, L. A., Mansfield, K. E., Douglas, I. J., Smeeth, L., and Nitsch, D., “Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study”, Br J Clin Pharmacol, vol. 84, pp. 2142-2151, 2018.
A. Jain, van Hoek, A. J., Walker, J. L., Forbes, H. J., Langan, S. M., Root, A., Smeeth, L., and Thomas, S. L., “Inequalities in zoster disease burden: a population-based cohort study to identify social determinants using linked data from the U.K. Clinical Practice Research Datalink”, Br J Dermatol, vol. 178, pp. 1324-1330, 2018.
U. Koppe, Nitsch, D., Mansfield, K. E., Mathur, R., Bhaskaran, K., Batterham, R. L., Smeeth, L., and Douglas, I. J., “Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink”, BMJ Open, vol. 8, p. e020371, 2018.
S. A. J. Schmidt, Langan, S. M., Pedersen, H. S., Schonheyder, H. C., Thomas, S. L., Smeeth, L., Mansfield, K. E., Sorensen, H. T., Forbes, H. J., and Vestergaard, M., “Mood Disorders and Risk of Herpes Zoster in 2 Population-Based Case-Control Studies in Denmark and the United Kingdom”, Am J Epidemiol, vol. 187, pp. 1019-1028, 2018.
K. J. Rothnie, Connell, O., Mullerova, H., Smeeth, L., Pearce, N., Douglas, I., and Quint, J. K., “Myocardial Infarction and Ischemic Stroke after Exacerbations of Chronic Obstructive Pulmonary Disease”, Ann Am Thorac Soc, vol. 15, pp. 935-946, 2018.
K. J. Rothnie, Mullerova, H., Smeeth, L., and Quint, J. K., “Natural History of Chronic Obstructive Pulmonary Disease Exacerbations in a General Practice-based Population with Chronic Obstructive Pulmonary Disease”, Am J Respir Crit Care Med, vol. 198, pp. 464-471, 2018.
K. Wing, Williamson, E., Carpenter, J. R., Wise, L., Schneeweiss, S., Smeeth, L., Quint, J. K., and Douglas, I., “Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results”, BMJ Open, vol. 8, p. e019475, 2018.
J. K. Quint, Moore, E., Lewis, A., Hashmi, M., Sultana, K., Wright, M., Smeeth, L., Chatzidiakou, L., Jones, R., Beevers, S., Kolozali, S., Kelly, F., and Barratt, B., “Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research”, NPJ Prim Care Respir Med, vol. 28, p. 21, 2018.
R. J. Silverwood, Forbes, H. J., Abuabara, K., Ascott, A., Schmidt, M., Schmidt, S. A. J., Smeeth, L., and Langan, S. M., “Severe and predominantly active atopic eczema in adulthood and long term risk of cardiovascular disease: population based cohort study”, Bmj, vol. 361, p. k1786, 2018.
M. Iwagami, Mansfield, K. E., Hayes, J. F., Walters, K., Osborn, D. P., Smeeth, L., Nitsch, D., and Tomlinson, L. A., “Severe mental illness and chronic kidney disease: a cross-sectional study in the United Kingdom”, Clin Epidemiol, vol. 10, pp. 421-429, 2018.
K. Chidwick, Strongman, H., Matthews, A., Stanway, S., Lyon, A. R., Smeeth, L., and Bhaskaran, K., “Statin use in cancer survivors versus the general population: cohort study using primary care data from the UK clinical practice research datalink”, BMC Cancer, vol. 18, p. 1018, 2018.
E. Crellin, Mansfield, K. E., Leyrat, C., Nitsch, D., Douglas, I. J., Root, A., Williamson, E., Smeeth, L., and Tomlinson, L. A., “Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study”, Bmj, vol. 360, p. k341, 2018.
A. Jain, Walker, J. L., Mathur, R., Forbes, H. J., Langan, S. M., Smeeth, L., van Hoek, A. J., and Thomas, S. L., “Zoster vaccination inequalities: A population based cohort study using linked data from the UK Clinical Practice Research Datalink”, PLoS One, vol. 13, p. e0207183, 2018.
2017
M. Schmidt, Mansfield, K. E., Bhaskaran, K., Nitsch, D., Sorensen, H. T., Smeeth, L., and Tomlinson, L. A., “Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin-angiotensin system blockade: a UK general practice-based cohort study”, BMJ Open, vol. 7, p. e012818, 2017.
S. J. Sinnott, Mansfield, K. E., Schmidt, M., Bhaskaran, K., Smeeth, L., Nitsch, D., and Tomlinson, L. A., “Biochemical monitoring after initiation of aldosterone antagonist therapy in users of renin-angiotensin system blockers: a UK primary care cohort study”, BMJ Open, vol. 7, p. e018153, 2017.
V. Navaratnam, Millett, E. R., Hurst, J. R., Thomas, S. L., Smeeth, L., Hubbard, R. B., Brown, J., and Quint, J. K., “Bronchiectasis and the risk of cardiovascular disease: a population-based study”, Thorax, vol. 72, pp. 161-166, 2017.
J. P. H. Wilding, Godec, T., Khunti, K., Pocock, S., Fox, R., Smeeth, L., Clauson, P., Fenici, P., Hammar, N., and Medina, J., “Changes in HbA1c and weight after initiation of second-line therapy in patients with type 2 diabetes in clinical practice.”, Diabetologia., vol. 60, p. S301, 2017.
E. Hansson, Forbes, H. J., Langan, S. M., Smeeth, L., and Bhaskaran, K., “Herpes zoster risk after 21 specific cancers: population-based case-control study”, Br J Cancer, vol. 116, pp. 1643-1651, 2017.
A. Jain, van Hoek, A. J., Walker, J. L., Mathur, R., Smeeth, L., and Thomas, S. L., “Identifying social factors amongst older individuals in linked electronic health records: An assessment in a population based study”, PLoS One, vol. 12, p. e0189038, 2017.
T. A. Yates, Tomlinson, L. A., Bhaskaran, K., Langan, S., Thomas, S., Smeeth, L., and Douglas, I. J., “Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort”, PLoS Med, vol. 14, p. e1002457, 2017.
S. A. Schmidt, Vestergaard, M., Pedersen, H. S., Schonheyder, H. C., Thomas, S. L., Smeeth, L., Mansfield, K. E., Sorensen, H. T., Forbes, H. J., and Langan, S. M., “Partner Bereavement and Risk of Herpes Zoster: Results from Two Population-Based Case-Control Studies in Denmark and the United Kingdom”, Clin Infect Dis, vol. 64, pp. 572-579, 2017.
R. Mathur, Bhaskaran, K., Edwards, E., Lee, H., Chaturvedi, N., Smeeth, L., and Douglas, I., “Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014”, BMJ Open, vol. 7, p. e014444, 2017.
M. Iwagami, Tomlinson, L. A., Mansfield, K. E., McDonald, H. I., Smeeth, L., and Nitsch, D., “Prevalence, incidence, indication, and choice of antidepressants in patients with and without chronic kidney disease: a matched cohort study in UK Clinical Practice Research Datalink”, Pharmacoepidemiol Drug Saf, vol. 26, pp. 792-801, 2017.
K. Wing, Bhaskaran, K., Pealing, L., Root, A., Smeeth, L., van Staa, T. P., Klungel, O. H., Reynolds, R. F., and Douglas, I., “Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study”, J Antimicrob Chemother, vol. 72, pp. 2636-2646, 2017.
M. Schmidt, Mansfield, K. E., Bhaskaran, K., Nitsch, D., Sorensen, H. T., Smeeth, L., and Tomlinson, L. A., “Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study”, Bmj, vol. 356, p. j791, 2017.
S. J. Sinnott, Smeeth, L., Williamson, E., and Douglas, I. J., “Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015”, Bmj, vol. 358, p. j3984, 2017.
J. L. Walker, Andrews, N. J., Mathur, R., Smeeth, L., and Thomas, S. L., “Trends in the burden of varicella in UK general practice”, Epidemiol Infect, vol. 145, pp. 2678-2682, 2017.
F. Nissen, Morales, D. R., Mullerova, H., Smeeth, L., Douglas, I. J., and Quint, J. K., “Validation of asthma recording in the Clinical Practice Research Datalink (CPRD)”, BMJ Open, vol. 7, p. e017474, 2017.
2016
M. Pujades-Rodriguez, Duyx, B., Thomas, S. L., Stogiannis, D., Smeeth, L., and Hemingway, H., “Associations between polymyalgia rheumatica and giant cell arteritis and 12 cardiovascular diseases”, Heart, vol. 102, pp. 383-9, 2016.
J. K. Quint, Millett, E. R., Joshi, M., Navaratnam, V., Thomas, S. L., Hurst, J. R., Smeeth, L., and Brown, J. S., “Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study”, Eur Respir J, vol. 47, pp. 186-93, 2016.
[Page last reviewed 4 October 2019]