Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 April 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 5MB, 226 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



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F. Lapi, Azoulay, L., Niazi, M. T., Yin, H., Benayoun, S., and Suissa, S., Androgen deprivation therapy and risk of acute kidney injury in patients with prostate cancer, Jama, vol. 310, pp. 289-96, 2013.
J. Assayag, Yin, H., Benayoun, S., Pollak, M. N., Suissa, S., and Azoulay, L., Androgen deprivation therapy and the risk of colorectal cancer in patients with prostate cancer, Cancer Causes Control, vol. 24, pp. 839-45, 2013.
L. Azoulay, Yin, H., Benayoun, S., Renoux, C., Boivin, J. F., and Suissa, S., Androgen-deprivation therapy and the risk of stroke in patients with prostate cancer, Eur Urol, vol. 60, pp. 1244-50, 2011.
V. Schneider-Lindner, Quach, C., Hanley, J. A., and Suissa, S., Antibacterial drugs and the risk of community-associated methicillin-resistant Staphylococcus aureus in children, Arch Pediatr Adolesc Med, vol. 165, pp. 1107-14, 2011.
S. Dial, Nessim, S. J., Kezouh, A., Benisty, J., and Suissa, S., Antihypertensive agents acting on the renin-angiotensin system and the risk of sepsis, Br J Clin Pharmacol, vol. 78, pp. 1151-8, 2014.
F. Khosrow-Khavar, Filion, K. B., Bouganim, N., Suissa, S., and Azoulay, L., Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study, Circulation, vol. 141, pp. 549-559, 2020.
F. Montastruc, Nie, R., Loo, S., Rej, S., Dell'Aniello, S., Micallef, J., Suissa, S., and Renoux, C., Association of Aripiprazole With the Risk for Psychiatric Hospitalization, Self-harm, or Suicide, JAMA Psychiatry, 2019.
S. Couraud, Azoulay, L., Dell'Aniello, S., and Suissa, S., Cardiac glycosides use and the risk of lung cancer: a nested case-control study, BMC Cancer, vol. 14, p. 573, 2014.
F. Khosrow-Khavar, Bouganim, N., Filion, K. B., Suissa, S., and Azoulay, L., Cardiotoxicity of Sequential Aromatase Inhibitors Use in Women with Breast Cancer, Am J Epidemiol, 2020.
L. Azoulay, Schneider-Lindner, V., Dell'Aniello, S., Schiffrin, A., and Suissa, S., Combination therapy with sulfonylureas and metformin and the prevention of death in type 2 diabetes: a nested case-control study, Pharmacoepidemiol Drug Saf, vol. 19, pp. 335-42, 2010.
M. O. Bernier, Mikaeloff, Y., Hudson, M., and Suissa, S., Combined oral contraceptive use and the risk of systemic lupus erythematosus, Arthritis Rheum, vol. 61, pp. 476-81, 2009.
A. Douros, Dell'Aniello, S., Yu, O. H. Y., and Suissa, S., Comparative cardiovascular and hypoglycemic safety of glimepiride in type 2 diabetes: A population-based cohort study, Diabetes Obes Metab, 2019.
L. Sinyavskaya, Gauthier, S., Renoux, C., Dell'Aniello, S., Suissa, S., and Brassard, P., Comparative effect of statins on the risk of incident Alzheimer disease, Neurology, vol. 90, pp. e179-e187, 2018.
S. Suissa, Dell'Aniello, S., and Ernst, P., Comparative effectiveness and safety of LABA-LAMA versus LABA-ICS treatment of COPD in real world clinical practice, Chest, 2019.
S. Suissa, Dell'Aniello, S., and Ernst, P., Comparative Effectiveness of Initial LAMA versus LABA in COPD: Real-World Cohort Study, Copd, vol. 18, pp. 1-8, 2021.
S. Suissa, Dell'Aniello, S., and Ernst, P., Comparative effectiveness of LABA-ICS versus LAMA as initial treatment in COPD targeted by blood eosinophils: a population-based cohort study, Lancet Respir Med, vol. 6, pp. 855-862, 2018.
S. Y. Loo, Coulombe, J., Dell'Aniello, S., Brophy, J. M., Suissa, S., and Renoux, C., Comparative effectiveness of novel oral anticoagulants in UK patients with non-valvular atrial fibrillation and chronic kidney disease: a matched cohort study, BMJ Open, vol. 8, p. e019638, 2018.
S. Suissa, Dell'Aniello, S., and Ernst, P., Comparative effects of LAMA-LABA-ICS versus LAMA-LABA for COPD: Cohort study in real world clinical practice: LAMA-LABA-ICS versus LAMA-LABA in COPD, Chest, 2019.
T. Tran and Suissa, S., Comparing New-User Cohort Designs: The Example of Proton Pump Inhibitor Effectiveness in Idiopathic Pulmonary Fibrosis, Am J Epidemiol, 2020.
L. Azoulay, Dell'Aniello, S., Simon, T., Renoux, C., and Suissa, S., The concurrent use of antithrombotic therapies and the risk of bleeding in patients with atrial fibrillation, Thromb Haemost, vol. 109, pp. 431-9, 2013.
F. Lapi, Azoulay, L., Yin, H., Nessim, S. J., and Suissa, S., Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal anti-inflammatory drugs and risk of acute kidney injury: nested case-control study, Bmj, vol. 346, p. e8525, 2013.
S. Suissa, Dell'Aniello, S., and Ernst, P., Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events, Eur Respir J, vol. 49, 2017.
J. P. Fournier, Duijnhoven, R. G., Renoux, C., Dell'Aniello, S., Klungel, O. H., and Suissa, S., Concurrent use of statins and hormone therapy and risk of venous thromboembolism in postmenopausal women: a population-based case-control study, Menopause, vol. 21, pp. 1023-6, 2014.
L. Azoulay, Dell'Aniello, S., Huiart, L., Fort, G. G. du, and Suissa, S., Concurrent use of tamoxifen with CYP2D6 inhibitors and the risk of breast cancer recurrence, Breast Cancer Res Treat, vol. 126, pp. 695-703, 2011.
F. Andersohn, Schade, R., Suissa, S., and Garbe, E., Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study, Stroke, vol. 37, pp. 1725-30, 2006.
S. S. Daskalopoulou, Delaney, J. A., Filion, K. B., Brophy, J. M., Mayo, N. E., and Suissa, S., Discontinuation of statin therapy following an acute myocardial infarction: a population-based study, Eur Heart J, vol. 29, pp. 2083-91, 2008.
C. Renoux, Dell'Aniello, S., Brophy, J. M., and Suissa, S., Dopamine agonist use and the risk of heart failure, Pharmacoepidemiol Drug Saf, vol. 21, pp. 34-41, 2012.
R. Schade, Andersohn, F., Suissa, S., Haverkamp, W., and Garbe, E., Dopamine agonists and the risk of cardiac-valve regurgitation, N Engl J Med, vol. 356, pp. 29-38, 2007.
N. Larivee, Suissa, S., Eberg, M., Joseph, L., Eisenberg, M. J., Abenhaim, H. A., and Filion, K. B., Drospirenone-containing combined oral contraceptives and the risk of arterial thrombosis: a population-based nested case-control study, Bjog, vol. 124, pp. 1672-1679, 2017.
N. Larivee, Suissa, S., Coulombe, J., Tagalakis, V., and Filion, K. B., Drospirenone-Containing Oral Contraceptive Pills and the Risk of Venous Thromboembolism: An Assessment of Risk in First-Time Users and Restarters, Drug Saf, vol. 40, pp. 583-596, 2017.
J. A. Delaney, Opatrny, L., Brophy, J. M., and Suissa, S., Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding, Cmaj, vol. 177, pp. 347-51, 2007.
I. Matok, Azoulay, L., Yin, H., and Suissa, S., Immortal time bias in observational studies of drug effects in pregnancy, Birth Defects Res A Clin Mol Teratol, vol. 100, pp. 658-62, 2014.
K. B. Filion, Delaney, J. A., Brophy, J. M., Ernst, P., and Suissa, S., The impact of over-the-counter simvastatin on the number of statin prescriptions in the United Kingdom: a view from the General Practice Research Database, Pharmacoepidemiol Drug Saf, vol. 16, pp. 1-4, 2007.
J. L. Faillie, Azoulay, L., Patenaude, V., Hillaire-Buys, D., and Suissa, S., Incretin based drugs and risk of acute pancreatitis in patients with type 2 diabetes: cohort study, Bmj, vol. 348, p. g2780, 2014.
O. H. Yu, Filion, K. B., Azoulay, L., Patenaude, V., Majdan, A., and Suissa, S., Incretin-based drugs and the risk of congestive heart failure, Diabetes Care, vol. 38, pp. 277-84, 2015.
A. Douros, Santella, C., Dell'Aniello, S., Azoulay, L., Renoux, C., Suissa, S., and Brassard, P., Infectious Disease Burden and the Risk of Alzheimer's Disease: A Population-Based Study, J Alzheimers Dis, 2021.
L. Azoulay, Dell'Aniello, S., Simon, T. A., Renoux, C., and Suissa, S., Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes, Eur Heart J, vol. 35, pp. 1881-7, 2014.
[Page last reviewed 6 April 2021]