Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 July 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 206 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



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A. Pate, Barrowman, M., Webb, D., Pimenta, J. M., Davis, K. J., Williams, R., Van Staa, T., and Sperrin, M., Study investigating the generalisability of a COPD trial based in primary care (Salford Lung Study) and the presence of a Hawthorne effect, BMJ Open Respir Res, vol. 5, p. e000339, 2018.
R. P. Cornish, Boyd, A., Van Staa, T., Salisbury, C., and Macleod, J., Socio-economic position and childhood multimorbidity: a study using linkage between the Avon Longitudinal Study of Parents and Children and the General Practice Research Database, Int J Equity Health, vol. 12, p. 66, 2013.
K. T. Palmer, D'Angelo, S., Harris, E. C., Linaker, C., Sayer, A. A., Gale, C. R., Evandrou, M., Van Staa, T., Cooper, C., and Coggon, D., Sleep disturbance and the older worker: findings from the Health and Employment after Fifty study, Scand J Work Environ Health, vol. 43, pp. 136-145, 2017.
D. F. Carr, O'Meara, H., Jorgensen, A. L., Campbell, J., Hobbs, M., McCann, G., Van Staa, T., and Pirmohamed, M., SLCO1B1 genetic variant associated with statin-induced myopathy: a proof-of-concept study using the clinical practice research datalink, Clin Pharmacol Ther, vol. 94, pp. 695-701, 2013.
M. Gulliford, Latinovic, R., Charlton, J., Little, P., Van Staa, T., and Ashworth, M., Selective decrease in consultations and antibiotic prescribing for acute respiratory tract infections in UK primary care up to 2006, J Public Health (Oxf), vol. 31, pp. 512-20, 2009.
A. R. Tate, Beloff, N., Al-Radwan, B., Wickson, J., Puri, S., Williams, T., Van Staa, T., and Bleach, A., Exploiting the potential of large databases of electronic health records for research using rapid search algorithms and an intuitive query interface, J Am Med Inform Assoc, vol. 21, pp. 292-8, 2014.
R. J. Moon, Harvey, N. C., Curtis, E. M., de Vries, F., Van Staa, T., and Cooper, C., Ethnic and geographic variations in the epidemiology of childhood fractures in the United Kingdom, Bone, vol. 85, pp. 9-14, 2016.
E. Herrett, Gadd, S., Jackson, R., Bhaskaran, K., Williamson, E., Van Staa, T., Sofat, R., Timmis, A., and Smeeth, L., Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study, Lancet, 2019.
M. C. Gulliford, Van Staa, T., Dregan, A., McDermott, L., McCann, G., Ashworth, M., Charlton, J., Little, P., Moore, M. V., and Yardley, L., Electronic health records for intervention research: a cluster randomized trial to reduce antibiotic prescribing in primary care (eCRT study), Ann Fam Med, vol. 12, pp. 344-51, 2014.
H. O'Meara, Carr, D. F., Evely, J., Hobbs, M., McCann, G., Van Staa, T., and Pirmohamed, M., Electronic health records for biological sample collection: feasibility study of statin-induced myopathy using the Clinical Practice Research Datalink, Br J Clin Pharmacol, vol. 77, pp. 831-8, 2014.
S. J. Ronaldson, Raghunath, A., Torgerson, D. J., and Van Staa, T., Cost-effectiveness of antibiotics for COPD management: observational analysis using CPRD data, ERJ Open Res, vol. 3, 2017.
E. Herrett, Shah, A. D., Boggon, R., Denaxas, S., Smeeth, L., Van Staa, T., Timmis, A., and Hemingway, H., Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study, Bmj, vol. 346, p. f2350, 2013.
S. Khalid, Calderon-Larranaga, S., Hawley, S., Ali, M. S., Judge, A., Arden, N., Van Staa, T., Cooper, C., Javaid, M. K., and Prieto-Alhambra, D., Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data: a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database, Clin Epidemiol, vol. 10, pp. 1417-1431, 2018.
A. Dregan, Van Staa, T., McDermott, L., McCann, G., Ashworth, M., Charlton, J., Wolfe, C., Rudd, A., Yardley, L., and Gulliford, M., Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial, Trials, vol. 13, p. 181, 2012.
M. C. Gulliford, Van Staa, T., McDermott, L., Dregan, A., McCann, G., Ashworth, M., Charlton, J., Grieve, A. P., Little, P., Moore, M. V., and Yardley, L., Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study), Trials, vol. 12, p. 115, 2011.
S. Rietbrock, Heeley, E., Plumb, J., and Van Staa, T., Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification scheme, Am Heart J, vol. 156, pp. 57-64, 2008.
[Page last reviewed 6 July 2020]