Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,600 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 4 January 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 218 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



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R. Alsaggaf, St George, D. M. M., Zhan, M., Pfeiffer, R. M., Wang, Y., Anderson, L. A., Liu, Z., Koshiol, J., Bauer, A. J., Wagner, K. R., Greene, M. H., Amr, S., and Gadalla, S. M., Benign tumors in myotonic dystrophy type I target disease-related cancer sites, Ann Clin Transl Neurol, vol. 6, pp. 1510-1518, 2019.
N. Ismail, Jordan, K. P., Kadam, U. T., Edwards, J. J., Kinnaird, T., and Mamas, M. A., Bleeding After Hospital Discharge Following Acute Coronary Syndrome: Incidence, Types, Timing, and Predictors, J Am Heart Assoc, vol. 8, p. e013679, 2019.
O. A. Oshagbemi, Franssen, F. M. E., van Kraaij, S., Braeken, D. C. W., Wouters, E. F. M., van der Zee, A. H. Maitlan, Driessen, J. H. M., and de Vries, F., Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD), Copd, pp. 1-8, 2019.
J. Gregson, Qizilbash, N., Iwagami, M., Douglas, I., Johnson, M., Pearce, N., and Pocock, S., Blood pressure and risk of dementia and its subtypes: a historical cohort study with long-term follow-up in 2.6 million people, Eur J Neurol, vol. 26, pp. 1479-1486, 2019.
H. Strongman, Brown, A., Smeeth, L., and Bhaskaran, K., Body mass index and Hodgkin's lymphoma: UK population-based cohort study of 5.8 million individuals, Br J Cancer, 2019.
J. P. Sheppard, Stevens, S., Stevens, R., Martin, U., Mant, J., Hobbs, F. D. R., and McManus, R. J., Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension, JAMA Intern Med, vol. 178, pp. 1626-1634, 2018.
D. B. Wolfson, Best, A. F., Addona, V., Wolfson, J., and Gadalla, S. M., Benefits of combining prevalent and incident cohorts: An application to myotonic dystrophy, Stat Methods Med Res, p. 962280218804275, 2018.
O. A. Oshagbemi, Franssen, F. M. E., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., van der Zee, A. H. Maitlan, Burden, A. M., and de Vries, F., Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality, Pharmacoepidemiol Drug Saf, vol. 27, pp. 1191-1199, 2018.
J. Delgado, Bowman, K., Ble, A., Masoli, J., Han, Y., Henley, W., Welsh, S., Kuchel, G. A., Ferrucci, L., and Melzer, D., Blood Pressure Trajectories in the 20 Years Before Death, JAMA Intern Med, vol. 178, pp. 93-99, 2018.
S. Kent, Jebb, S. A., Gray, A., Green, J., Reeves, G., Beral, V., Mihaylova, B., and Cairns, B. J., Body mass index and use and costs of primary care services among women aged 55-79 years in England: a cohort and linked data study, Int J Obes (Lond), 2018.
E. A. Yanni, Ferreira, G., Guennec, M., Y. Hahi, E., A. Ghachi, E., Haguinet, F., Espie, E., and Bianco, V., Burden of herpes zoster in 16 selected immunocompromised populations in England: a cohort study in the Clinical Practice Research Datalink 2000-2012, BMJ Open, vol. 8, p. e020528, 2018.
C. Renoux, Dell'Aniello, S., Brenner, B., and Suissa, S., Bias from depletion of susceptibles: the example of hormone replacement therapy and the risk of venous thromboembolism, Pharmacoepidemiol Drug Saf, vol. 26, pp. 554-560, 2017.
S. J. Sinnott, Mansfield, K. E., Schmidt, M., Bhaskaran, K., Smeeth, L., Nitsch, D., and Tomlinson, L. A., Biochemical monitoring after initiation of aldosterone antagonist therapy in users of renin-angiotensin system blockers: a UK primary care cohort study, BMJ Open, vol. 7, p. e018153, 2017.
W. G. Herrington, Smith, M., Bankhead, C., Matsushita, K., Stevens, S., Holt, T., Hobbs, F. D., Coresh, J., and Woodward, M., Body-mass index and risk of advanced chronic kidney disease: Prospective analyses from a primary care cohort of 1.4 million adults in England, PLoS One, vol. 12, p. e0173515, 2017.
V. Navaratnam, Millett, E. R., Hurst, J. R., Thomas, S. L., Smeeth, L., Hubbard, R. B., Brown, J., and Quint, J. K., Bronchiectasis and the risk of cardiovascular disease: a population-based study, Thorax, vol. 72, pp. 161-166, 2017.
S. Langham, Wright, A., Shaw, H., Bryson, S., and O'Leary, S., Budget impact analysis of oral glycopyrronium bromide (Sialanar™) for the symptomatic treatment of severe sialorrhoea (Drooling) in the UK setting, Value in Health, vol. 20, p. A720, 2017.
K. van Brunt, Curtis, B., Ivanyi, T., Balogh, E., Chalkiadaki, C., MacLachlan, S., Neasham, D., and Raluy-Callado, M., Basal-bolus Therapy in Patients with Type 2 Diabetes Mellitus in the UK: Patient Characteristics, Treatment Patterns and the Effect of Switching to Premixed Insulin, Diabetes Ther, vol. 7, pp. 793-807, 2016.
J. Spoendlin, Meier, C., Jick, S. S., and Meier, C. R., Bisphosphonate therapy start may transiently increase the risk of tendon rupture in patients with glucocorticoid co-medication: a population-based observational study, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1116-1123, 2016.
C. Ang, Doyle, E., and Branch, A., Bisphosphonates as potential adjuvants for patients with cancers of the digestive system, World J Gastroenterol, vol. 22, pp. 906-16, 2016.
C. A. Emdin, Rothwell, P. M., Salimi-Khorshidi, G., Kiran, A., Conrad, N., Callender, T., Mehta, Z., Pendlebury, S. T., Anderson, S. G., Mohseni, H., Woodward, M., and Rahimi, K., Blood Pressure and Risk of Vascular Dementia: Evidence From a Primary Care Registry and a Cohort Study of Transient Ischemic Attack and Stroke, Stroke, vol. 47, pp. 1429-35, 2016.
F. Rees, Doherty, M., Grainge, M., Lanyon, P., Davenport, G., and Zhang, W., Burden of Comorbidity in Systemic Lupus Erythematosus in the UK, 1999-2012, Arthritis Care Res (Hoboken), vol. 68, pp. 819-27, 2016.
I. J. Douglas, Bhaskaran, K., Batterham, R. L., and Smeeth, L., Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care, PLoS Med, vol. 12, p. e1001925, 2015.
P. Imfeld, Bodmer, M., Jick, S. S., and Meier, C. R., Benzodiazepine Use and Risk of Developing Alzheimer's Disease or Vascular Dementia: A Case-Control Analysis, Drug Saf, vol. 38, pp. 909-19, 2015.
A. Palmaro, Dupouy, J., and Lapeyre-Mestre, M., Benzodiazepines and risk of death: Results from two large cohort studies in France and UK, Eur Neuropsychopharmacol, vol. 25, pp. 1566-77, 2015.
N. Qizilbash, Gregson, J., Johnson, M. E., Pearce, N., Douglas, I., Wing, K., Evans, S. J. W., and Pocock, S. J., BMI and risk of dementia in two million people over two decades: a retrospective cohort study, Lancet Diabetes Endocrinol, vol. 3, pp. 431-436, 2015.
J. H. Driessen, Henry, R. M., van Onzenoort, H. A., Lalmohamed, A., Burden, A. M., Prieto-Alhambra, D., Neef, C., Leufkens, H. G., and de Vries, F., Bone fracture risk is not associated with the use of glucagon-like peptide-1 receptor agonists: a population-based cohort analysis, Calcif Tissue Int, vol. 97, pp. 104-12, 2015.
R. D. Pockett, Watkins, J., McEwan, P., and Meier, G., Burden of Illness in UK Subjects with Reported Respiratory Infections Vaccinated or Unvaccinated against Influenza: A Retrospective Observational Study, PLoS One, vol. 10, p. e0134928, 2015.
[Page last reviewed 5 January 2021]