Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
A. Henderson, Iwagami, M., Bottomley, C., Tomlinson, L., Mansfield, K., and Nitsch, D., Paediatric acute kidney injury hospital admissions in England 1997–2014: burden and risk factors, Clinical Kidney Journal, 2019.
R. Williams, Kothny, W., Serban, C., Lopez-Leon, S., and Schlienger, R., Pancreatic safety of vildagliptin in patients with type 2 diabetes mellitus: A European, noninterventional, postauthorization safety study, Endocrinol Diabetes Metab, vol. 2, p. e00052, 2019.
H. J. Forbes, Wong, A. Y. S., Morton, C., Bhaskaran, K., Smeeth, L., Richards, M., Schmidt, S. A. J., Langan, S. M., and Warren-Gash, C., Partner Bereavement and Detection of Dementia: A UK-Based Cohort Study Using Routine Health Data, J Alzheimers Dis, 2019.
S. Lay-Flurrie, Mathieu, E., Bankhead, C., Nicholson, B. D., Perera-Salazar, R., Holt, T., Hobbs, F. D. R., and Salisbury, C., Patient consultation rate and clinical and NHS outcomes: a cross-sectional analysis of English primary care data from 2.7 million patients in 238 practices, BMC Health Serv Res, vol. 19, p. 219, 2019.
J. S. Floyd, Bloch, K. M., Brody, J. A., Maroteau, C., Siddiqui, M. K., Gregory, R., Carr, D. F., Molokhia, M., Liu, X., Bis, J. C., Ahmed, A., Liu, X., Hallberg, P., Yue, Q. Y., Magnusson, P. K. E., Brisson, D., Wiggins, K. L., Morrison, A. C., Khoury, E., McKeigue, P., Stricker, B. H., Lapeyre-Mestre, M., Heckbert, S. R., Gallagher, A. M., Chinoy, H., Gibbs, R. A., Bondon-Guitton, E., Tracy, R., Boerwinkle, E., Gaudet, D., Conforti, A., Van Staa, T., Sitlani, C. M., Rice, K. M., van der Zee, A. H. Maitlan, Wadelius, M., Morris, A. P., Pirmohamed, M., Palmer, C. A. N., Psaty, B. M., and Alfirevic, A., Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing, PLoS One, vol. 14, p. e0218115, 2019.
X. Sun, Douiri, A., and Gulliford, M., Pneumonia incidence trends in UK primary care from 2002 to 2017: population-based cohort study, Epidemiol Infect, vol. 147, p. e263, 2019.
R. Denholm, Morris, R., and Payne, R., Polypharmacy patterns in the last year of life in patients with dementia, Eur J Clin Pharmacol, 2019.
C. I. Bloom, Ricciardi, F., Smeeth, L., Stone, P., and Quint, J. K., Predicting COPD 1-year mortality using prognostic predictors routinely measured in primary care, BMC Med, vol. 17, p. 73, 2019.
S. F. Weng, Vaz, L., Qureshi, N., and Kai, J., Prediction of premature all-cause mortality: A prospective general population cohort study comparing machine-learning and standard epidemiological approaches, PLoS One, vol. 14, p. e0214365, 2019.
J. Watson, Salisbury, C., Banks, J., Whiting, P., and Hamilton, W., Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records, Br J Cancer, 2019.
S. Venkatesan, Jorgensen, M. E., Manning, H. J., Andersson, C., Mozid, A. M., Coburn, M., Moonesinghe, S. R., Foex, P., Mythen, M., Grocott, M. P. W., Hardman, J. G., Myles, P. R., and Sanders, R. D., Preoperative chronic beta-blocker prescription in elderly patients as a risk factor for postoperative mortality stratified by preoperative blood pressure: a cohort study, Br J Anaesth, 2019.
T. Newlove-Delgado, Hamilton, W., Ford, T. J., Stein, K., and Ukoumunne, O. C., Prescribing for young people with attention deficit hyperactivity disorder in UK primary care: analysis of data from the Clinical Practice Research Datalink, Atten Defic Hyperact Disord, 2019.
M. J. Carr, Ashcroft, D. M., White, P. D., Kapur, N., and Webb, R. T., Prevalence of comorbid mental and physical illnesses and risks for self-harm and premature death among primary care patients diagnosed with fatigue syndromes, Psychol Med, pp. 1-8, 2019.
D. Lautsch, Wang, T., Yang, L., and Rajpathak, S. N., Prevalence of Established Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in the UK, Diabetes Ther, 2019.
K. M. Abel, Hope, H., Swift, E., Parisi, R., Ashcroft, D. M., Kosidou, K., Osam, C. S., Dalman, C., and Pierce, M., Prevalence of maternal mental illness among children and adolescents in the UK between 2005 and 2017: a national retrospective cohort analysis, Lancet Public Health, vol. 4, pp. e291-e300, 2019.
V. W. Zhong, Juhaeri, J., Cole, S. R., Shay, C. M., Gordon-Larsen, P., Kontopantelis, E., and Mayer-Davis, E. J., Proximal HbA1C Level and First Hypoglycemia Hospitalization in Adults with Incident Type 2 Diabetes, J Clin Endocrinol Metab, 2019.
2018
K. Gruntz, Bloechliger, M., Becker, C., Jick, S. S., Fuhr, P., Meier, C. R., and Ruegg, S., Parkinson disease and the risk of epileptic seizures, Ann Neurol, vol. 83, pp. 363-374, 2018.
H. J. I. De Jong, Tervaert, J. W. Cohen, Lalmohamed, A., de Vries, F., Vandebriel, R. J., Van Loveren, H., Klungel, O. H., and van Staa, T. P., Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink, PLoS One, vol. 13, p. e0193297, 2018.
J. Tran, Norton, R., Conrad, N., Rahimian, F., Canoy, D., Nazarzadeh, M., and Rahimi, K., Patterns and temporal trends of comorbidity among adult patients with incident cardiovascular disease in the UK between 2000 and 2014: A population-based cohort study, PLoS Med, vol. 15, p. e1002513, 2018.
A. V. Margulis, Linder, M., Arana, A., Pottegard, A., Berglind, I. A., Bui, C. L., Kristiansen, N. S., Bahmanyar, S., McQuay, L. J., Atsma, W. J., Appenteng, K., D'Silva, M., Perez-Gutthann, S., and Hallas, J., Patterns of use of antimuscarinic drugs to treat overactive bladder in Denmark, Sweden, and the United Kingdom, PLoS One, vol. 13, p. e0204456, 2018.
L. McDonald, Schultze, A., Carroll, R., and Ramagopalan, S. V., Performing studies using the UK Clinical Practice Research Datalink: to link or not to link?, Eur J Epidemiol, vol. 33, pp. 601-605, 2018.
F. A. Achana, Fleming, K. M., Tata, L. J., Sultan, A. A., and Petrou, S., Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data, Bjog, vol. 125, pp. 874-883, 2018.
M. Sabido, Hohenberger, T., and Grassi, G., Pharmacological intervention in hypertension using beta-blockers: Real-world evidence for long-term effectiveness, Pharmacol Res, vol. 130, pp. 191-197, 2018.
H. Strongman, Christopher, S., Majak, M., Williams, R., Bahmanyar, S., Linder, M., Heintjes, E. M., Bennett, D., Korhonen, P., and Hoti, F., Pioglitazone and cause-specific risk of mortality in patients with type 2 diabetes: extended analysis from a European multidatabase cohort study, BMJ Open Diabetes Res Care, vol. 6, p. e000481, 2018.
E. G. Tyrrell, Kendrick, D., Sayal, K., and Orton, E., Poisoning substances taken by young people: a population-based cohort study, Br J Gen Pract, vol. 68, pp. e703-e710, 2018.
A. Cherskov, Pohl, A., Allison, C., Zhang, H., Payne, R. A., and Baron-Cohen, S., Polycystic ovary syndrome and autism: A test of the prenatal sex steroid theory, Transl Psychiatry, vol. 8, p. 136, 2018.
T. R. Berni, Morgan, C. L., Berni, E. R., and Rees, D. A., Polycystic Ovary Syndrome Is Associated With Adverse Mental Health and Neurodevelopmental Outcomes, J Clin Endocrinol Metab, vol. 103, pp. 2116-2125, 2018.
S. Jenkins-Jones, Parviainen, L., Porter, J., Withe, M., Whitaker, M. J., Holden, S. E., Morgan, C. L., Currie, C. J., and Ross, R. J. M., Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia, Eur J Endocrinol, vol. 178, pp. 309-320, 2018.
J. R. Ingram, Jenkins-Jones, S., Knipe, D. W., Morgan, C. L. I., Cannings-John, R., and Piguet, V., Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis suppurativa, Br J Dermatol, vol. 178, pp. 917-924, 2018.
J. Busby, Mills, K., Zhang, S. D., Liberante, F. G., and Cardwell, C. R., Postdiagnostic Calcium Channel Blocker Use and Breast Cancer Mortality: A Population-based Cohort Study, Epidemiology, vol. 29, pp. 407-413, 2018.
A. M. Mueller, Meier, C. R., Jick, S. S., and Schneider, C., The Potential of Glycemic Control and Body Weight Change as Early Markers for Pancreatic Cancer in Patients With Long-standing Diabetes Mellitus: A Case-Control Study, PancreasPancreasPancreas, vol. 47, pp. 807-815, 2018.
J. W. O'Sullivan, Stevens, S., Oke, J., Hobbs, F. D. R., Salisbury, C., Little, P., Goldacre, B., Bankhead, C., Aronson, J. K., Heneghan, C., and Perera, R., Practice variation in the use of tests in UK primary care: a retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16, BMC Med, vol. 16, p. 229, 2018.
J. M. Dennis, Shields, B. M., Hill, A. V., Knight, B. A., McDonald, T. J., Rodgers, L. R., Weedon, M. N., Henley, W. E., Sattar, N., Holman, R. R., Pearson, E. R., Hattersley, A. T., and Jones, A. G., Precision Medicine in Type 2 Diabetes: Clinical Markers of Insulin Resistance Are Associated With Altered Short- and Long-term Glycemic Response to DPP-4 Inhibitor Therapy, Diabetes Care, vol. 41, pp. 705-712, 2018.
S. W. D. Merriel, May, M. T., and Martin, R. M., Predicting prostate cancer progression: protocol for a retrospective cohort study to identify prognostic factors for prostate cancer outcomes using routine primary care data, BMJ Open, vol. 8, p. e019409, 2018.
C. L. Burton, Chesterton, L. S., Chen, Y., and van der Windt, D. A., Predicting surgical intervention in patients presenting with carpal tunnel syndrome in primary care, Clin Epidemiol, vol. 10, pp. 739-748, 2018.
F. Rahimian, Salimi-Khorshidi, G., Payberah, A. H., Tran, J., R. Solares, A., Raimondi, F., Nazarzadeh, M., Canoy, D., and Rahimi, K., Predicting the risk of emergency admission with machine learning: Development and validation using linked electronic health records, PLoS Med, vol. 15, p. e1002695, 2018.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Predictors and temporal trend of flu vaccination in auto-immune rheumatic diseases in the UK: a nationwide prospective cohort study, Rheumatology (Oxford), vol. 57, pp. 1726-1734, 2018.
T. Newlove-Delgado, Ford, T. J., Hamilton, W., Stein, K., and Ukoumunne, O. C., Prescribing of medication for attention deficit hyperactivity disorder among young people in the Clinical Practice Research Datalink 2005-2013: analysis of time to cessation, Eur Child Adolesc Psychiatry, vol. 27, pp. 29-35, 2018.
D. Spanopoulos, Barrett, B., Busse, M., Roman, T., and Poole, C., Prescription of DPP-4 Inhibitors to Patients With Adult Type 2 Diabetes Mellitus and Creatinine Clearance>50 mL/min: The UK Primary Care Experience, Clin Ther, vol. 40, pp. 1424-1428.e4, 2018.
D. Spanopoulos, Barrett, B., Busse, M., Roman, T., and Poole, C., Prescription of DPP-4 Inhibitors to Type 2 Diabetes Mellitus Patients With Renal Impairment: A UK Primary Care Experience, Clin Ther, vol. 40, pp. 152-154, 2018.
S. H. Mahmoudpour, Asselbergs, F. W., Souverein, P. C., de Boer, A., and van der Zee, A. H. Maitlan, Prescription patterns of angiotensin-converting enzyme inhibitors for various indications: A UK population-based study, Br J Clin Pharmacol, vol. 84, pp. 2365-2372, 2018.
M. D. Danese, Sidelnikov, E., and Kutikova, L., The prevalence, low-density lipoprotein cholesterol levels, and treatment of patients at very high risk of cardiovascular events in the United Kingdom: a cross-sectional study, Curr Med Res Opin, vol. 34, pp. 1441-1447, 2018.
G. Disanto, Zecca, C., MacLachlan, S., Sacco, R., Handunnetthi, L., Meier, U. C., Simpson, A., McDonald, L., Rossi, A., Benkert, P., Kuhle, J., Ramagopalan, S. V., and Gobbi, C., Prodromal symptoms of multiple sclerosis in primary care, Ann Neurol, vol. 83, pp. 1162-1173, 2018.
P. Imfeld, Bodmer, M., Jick, S. S., and Meier, C. R., Proton Pump Inhibitor Use and Risk of Developing Alzheimer's Disease or Vascular Dementia: A Case-Control Analysis, Drug Saf, vol. 41, pp. 1387-1396, 2018.
V. S. Hegade, Mells, G. F., Fisher, H., Kendrick, S., DiBello, J., Gilchrist, K., Alexander, G. J., Hirschfield, G. M., Sandford, R. N., and Jones, D. E. J., Pruritus is Common and Under-treated in Patients with Primary Biliary Cholangitis in the United Kingdom, Clin Gastroenterol Hepatol, 2018.
R. Houghton, Liu, C., and Bolognani, F., Psychiatric Comorbidities and Psychotropic Medication Use in Autism: A Matched Cohort Study with ADHD and General Population Comparator Groups in the United Kingdom, Autism Res, 2018.
R. Parisi, Webb, R. T., Kleyn, C. E., Carr, M. J., Kapur, N., Griffiths, C. E. M., and Ashcroft, D. M., Psychiatric morbidity and suicidal behaviour in psoriasis: a primary care cohort study, Br J Dermatol, 2018.
[Page last reviewed 4 November 2019]