Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 April 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 5MB, 226 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



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Author Title Type [ Year(Desc)]
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S. de Lusignan, Brown, A., and Majeed, A., Recent developments in general practice computing, Clinician in Management, vol. 7, pp. 148-154, 1998.
J. Castellsague, S. Gutthann, P., and Rodriguez, L. A. Garcia, Recent epidemiological studies of the association between hormone replacement therapy and venous thromboembolism. A review, Drug Saf, vol. 18, pp. 117-23, 1998.
R. G. Gibbs, Todd, J. C., Irvine, C., Lawrenson, R., Newson, R., Greenhalgh, R. M., and Davies, A. H., Relationship between the regional and national incidence of transient ischaemic attack and stroke and performance of carotid endarterectomy, Eur J Vasc Endovasc Surg, vol. 16, pp. 47-52, 1998.
L. A. Garcia Rodriguez, Cattaruzzi, C., Troncon, M. G., and Agostinis, L., Risk of hospitalization for upper gastrointestinal tract bleeding associated with ketorolac, other nonsteroidal anti-inflammatory drugs, calcium antagonists, and other antihypertensive drugs, Arch Intern Med, vol. 158, pp. 33-9, 1998.
H. Jick, Derby, L. E., Vasilakis, C., and Fife, D., The risk of seizures associated with tramadol, Pharmacotherapy, vol. 18, pp. 607-11, 1998.
T. Lancaster, Swart, A. M., and Jick, H., Risk of serious haematological toxicity with use of chloramphenicol eye drops in a British general practice database, Bmj, vol. 316, p. 667, 1998.
M. Frischer, Heatlie, H., Chapman, S., Bashford, J., Norwood, J., and Millson, D., Ratio of inhaled corticosteroid to bronchodilator treatment and asthma hospitalisation, Curr Med Res Opin, vol. 16, pp. 8-13, 2000.
J. B. Soriano, Maier, W. C., Egger, P., Visick, G., Thakrar, B., Sykes, J., and Pride, N. B., Recent trends in physician diagnosed COPD in women and men in the UK, Thorax, vol. 55, pp. 789-94, 2000.
L. A. Garcia Rodriguez and Huerta-Alvarez, C., Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: a pooled analysis of published studies and a new population-based study, Epidemiology, vol. 11, pp. 376-81, 2000.
S. Rowlands, Devalia, H., Lawrenson, R., Logie, J., and Ineichen, B., Repeated use of hormonal emergency contraception by younger women in the UK, Br J Fam Plann, vol. 26, pp. 138-43, 2000.
I. A. Eland, Alvarez, C. H., Stricker, B. H., and Rodriguez, L. A., The risk of acute pancreatitis associated with acid-suppressing drugs, Br J Clin Pharmacol, vol. 49, pp. 473-8, 2000.
L. Derby and Maier, W. C., Risk of cataract among users of intranasal corticosteroids, J Allergy Clin Immunol, vol. 105, pp. 912-6, 2000.
S. S. Jick, The risk of gastrointestinal bleed, myocardial infarction, and newly diagnosed hypertension in users of meloxicam, diclofenac, naproxen, and piroxicam, Pharmacotherapy, vol. 20, pp. 741-4, 2000.
C. Gasse, Derby, L. E., Vasilakis, C., and Jick, H., Risk of suicide among users of calcium channel blockers: population based, nested case-control study, Bmj, vol. 320, p. 1251, 2000.
H. Jick, Kaye, J. A., Vasilakis-Scaramozza, C., and Jick, S. S., Risk of venous thromboembolism among users of third generation oral contraceptives compared with users of oral contraceptives with levonorgestrel before and after 1995: cohort and case-control analysis, Bmj, vol. 321, pp. 1190-5, 2000.
L. A. Garcia-Rodriguez and Huerta-Alvarez, C., Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs, Epidemiology, vol. 12, pp. 88-93, 2001.
L. A. Garcia Rodriguez and Hernandez-Diaz, S., Relative risk of upper gastrointestinal complications among users of acetaminophen and nonsteroidal anti-inflammatory drugs, Epidemiology, vol. 12, pp. 570-6, 2001.
R. Lawrenson, Wyndaele, J. J., Vlachonikolis, I., Farmer, C., and Glickman, S., Renal failure in patients with neurogenic lower urinary tract dysfunction, Neuroepidemiology, vol. 20, pp. 138-43, 2001.
S. S. Jick, Vasilakis-Scaramozza, C., and Maier, W. C., The risk of cataract among users of inhaled steroids, Epidemiology, vol. 12, pp. 229-34, 2001.
R. G. Schlienger, Haefeli, W. E., Jick, H., and Meier, C. R., Risk of cataract in patients treated with statins, Arch Intern Med, vol. 161, pp. 2021-6, 2001.
H. E. Seaman, Lawrenson, R. A., Williams, T. J., MacRae, K. D., and Farmer, R. D., The risk of liver damage associated with minocycline: a comparative study, J Clin Pharmacol, vol. 41, pp. 852-60, 2001.
C. Huerta, Rodriguez, L. A. Garcia, Moller, C. S., and Arellano, F. M., The risk of obstructive airways disease in a glaucoma population, Pharmacoepidemiol Drug Saf, vol. 10, pp. 157-63, 2001.
F. J. de Abajo and Rodriguez, L. A. Garcia, Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations, BMC Clin Pharmacol, vol. 1, p. 1, 2001.
L. A. Garcia Rodriguez and Hernandez-Diaz, S., The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents, Arthritis Res, vol. 3, pp. 98-101, 2001.
C. Vasilakis-Scaramozza and Jick, H., Risk of venous thromboembolism with cyproterone or levonorgestrel contraceptives, Lancet, vol. 358, pp. 1427-9, 2001.
C. Black, Kaye, J. A., and Jick, H., Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database, Bmj, vol. 325, pp. 419-21, 2002.
S. F. Lanes, Rodriguez, L. A. Garcia, and Huerta, C., Respiratory medications and risk of asthma death, Thorax, vol. 57, pp. 683-6, 2002.
C. Huerta, Zhao, S. Z., and Rodriguez, L. A. Garcia, Risk of acute liver injury in patients with diabetes, Pharmacotherapy, vol. 22, pp. 1091-6, 2002.
C. Huerta and Rodriguez, L. A. Garcia, Risk of clinical blood dyscrasia in a cohort of antibiotic users, Pharmacotherapy, vol. 22, pp. 630-6, 2002.
C. Huerta, Rodriguez, L. A. Garcia, Wallander, M. A., and Johansson, S., Risk of irritable bowel syndrome among asthma patients, Pharmacoepidemiol Drug Saf, vol. 11, pp. 31-5, 2002.
A. Ruigomez, Johansson, S., Wallander, M. A., and Rodriguez, L. A. Garcia, Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillation, BMC Cardiovasc Disord, vol. 2, p. 5, 2002.
J. Castellsague, Garcia-Rodriguez, L. A., Duque, A., and Perez, S., Risk of serious skin disorders among users of oral antifungals: a population-based study, BMC Dermatol, vol. 2, p. 14, 2002.
[Page last reviewed 6 April 2021]