Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 October 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
N. Conrad, Judge, A., Canoy, D., Tran, J., Pinho-Gomes, A. C., Millett, E. R. C., Salimi-Khorshidi, G., Cleland, J. G., McMurray, J. J. V., and Rahimi, K., “Temporal Trends and Patterns in Mortality After Incident Heart Failure: A Longitudinal Analysis of 86000 Individuals”, JAMA Cardiol, 2019.
D. Spanopoulos, Okhai, H., Zaccardi, F., Tebboth, A., Barrett, B., Busse, M., Webb, J., and Khunti, K., “Temporal variation of renal function in people with type 2 diabetes mellitus: a retrospective UK Clinical Practice Research Datalink cohort study”, Diabetes Obes Metab, 2019.
C. Santella, Renoux, C., Yin, H., Yu, O. H. Y., and Azoulay, L., “Testosterone Replacement Therapy and the Risk of Prostate Cancer in Men with Late-Onset Hypogonadism”, Am J Epidemiol, 2019.
J. M. Dennis, Henley, W. E., McGovern, A. P., Farmer, A. J., Sattar, N., Holman, R. R., Pearson, E. R., Hattersley, A. T., Shields, B. M., and Jones, A. G., “Time trends in prescribing of type 2 diabetes drugs, glycemic response and risk factors: a retrospective analysis of primary care data, 2010-2017”, Diabetes Obes Metab, 2019.
C. J. Czoski Murray, Kingsbury, S. R., Arden, N. K., Hewison, J., Judge, A., Matu, J., O'Shea, J., Pinedo-Villanueva, R., Smith, L. K., Smith, C., Thomas, C. M., West, R. M., Wright, J. M., Conaghan, P. G., and Stone, M. H., “Towards UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): protocol for an evaluation of the requirements for arthroplasty follow-up, and the production of consensus-based recommendations”, BMJ Open, vol. 9, p. e031351, 2019.
J. L. Rees, Shah, A., Edwards, K., Sanchez-Santos, M. T., Robinson, D. E., Delmestri, A., Carr, A., Arden, N., Lamb, S. E., Rangan, A., Judge, A., Pinedo-Villanueva, R., Holt, T., Hopewell, S., Prieto-Alhambra, D., and Collins, G., “Treatment of first-time traumatic anterior shoulder dislocation: the UK TASH-D cohort study”, Health Technol Assess, vol. 23, pp. 1-104, 2019.
T. Appleyard, Ashworth, J., Bedson, J., Yu, D., and Peat, G., “Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care”, Osteoarthritis Cartilage, 2019.
B. Feakins, Oke, J., McFadden, E., Aronson, J., Lasserson, D., O'Callaghan, C., Taylor, C., Hill, N., Stevens, R., and Perera, R., “Trends in kidney function testing in UK primary care since the introduction of the quality and outcomes framework: a retrospective cohort study using CPRD”, BMJ Open, vol. 9, p. e028062, 2019.
C. J. Taylor, Ordonez-Mena, J. M., Roalfe, A. K., Lay-Flurrie, S., Jones, N. R., Marshall, T., and Hobbs, F. D. R., “Trends in survival after a diagnosis of heart failure in the United Kingdom 2000-2017: population based cohort study”, Bmj, vol. 364, p. l223, 2019.
C. Group on H. Cancer, “Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence”, Lancet, vol. 394, pp. 1159-1168, 2019.
2018
N. Conrad, Judge, A., Tran, J., Mohseni, H., Hedgecott, D., Crespillo, A. P., Allison, M., Hemingway, H., Cleland, J. G., McMurray, J. J. V., and Rahimi, K., “Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals”, Lancet, vol. 391, pp. 572-580, 2018.
J. W. O'Sullivan, Stevens, S., Hobbs, F. D. R., Salisbury, C., Little, P., Goldacre, B., Bankhead, C., Aronson, J. K., Perera, R., and Heneghan, C., “Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests”, Bmj, vol. 363, p. k4666, 2018.
C. Martinez, Katholing, A., Folkerts, K., and Rietbrock, S., “Thirteen-year trend in the persistence with vitamin K antagonists for venous thromboembolism in the UK: a cohort study”, Curr Med Res Opin, vol. 34, pp. 1985-1990, 2018.
U. Desai, Kirson, N. Y., Kim, J., Khunti, K., King, S., Trieschman, E., Hellstern, M., Hunt, P. R., and Mukherjee, J., “Time to Treatment Intensification After Monotherapy Failure and Its Association With Subsequent Glycemic Control Among 93,515 Patients With Type 2 Diabetes”, Diabetes Care, vol. 41, pp. 2096-2104, 2018.
H. J. Curtis, Dennis, J. M., Shields, B. M., Walker, A. J., Bacon, S., Hattersley, A. T., Jones, A. G., and Goldacre, B., “Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017”, Diabetes Obes Metab, vol. 20, pp. 2159-2168, 2018.
S. M. Grandi, Reynier, P., Platt, R. W., Basso, O., and Filion, K. B., “The timing of onset of hypertensive disorders in pregnancy and the risk of incident hypertension and cardiovascular disease”, Int J Cardiol, vol. 270, pp. 273-275, 2018.
J. A. Hirst, Farmer, A. J., Smith, M. C., and Stevens, R. J., “Timings for HbA1c testing in people with diabetes are associated with incentive payments: an analysis of UK primary care data”, Diabet Med, 2018.
J. Charlton, Ravindrarajah, R., Hamada, S., Jackson, S. H., and Gulliford, M. C., “Trajectory of Total Cholesterol in the Last Years of Life Over Age 80 Years: Cohort Study of 99,758 Participants”, J Gerontol A Biol Sci Med Sci, vol. 73, pp. 1083-1089, 2018.
J. Gordon, McEwan, P., Idris, I., Evans, M., and Puelles, J., “Treatment choice, medication adherence and glycemic efficacy in people with type 2 diabetes: a UK clinical practice database study”, BMJ Open Diabetes Res Care, vol. 6, p. e000512, 2018.
I. Idris, Peng, X., He, X., Liu, D., Balogh, E., Kaushik, P., and van Brunt, K., “The Trend of High-Dose Insulin Usage Among Patients with Diabetes in the UK: A Retrospective Study”, Diabetes Ther, vol. 9, pp. 2245-2257, 2018.
E. Burn, Edwards, C. J., Murray, D. W., Silman, A., Cooper, C., Arden, N. K., Pinedo-Villanueva, R., and Prieto-Alhambra, D., “Trends and determinants of length of stay and hospital reimbursement following knee and hip replacement: evidence from linked primary care and NHS hospital records from 1997 to 2014”, BMJ Open, vol. 8, p. e019146, 2018.
V. W. Zhong, Juhaeri, J., and Mayer-Davis, E. J., “Trends in Hospital Admission for Diabetic Ketoacidosis in Adults With Type 1 and Type 2 Diabetes in England, 1998-2013: A Retrospective Cohort Study”, Diabetes Care, vol. 41, pp. 1870-1877, 2018.
O. A. Oshagbemi, Keene, S. J., Driessen, J. H. M., Jordan, R., Wouters, E. F. M., de Boer, A., de Vries, F., and Franssen, F. M. E., “Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013”, Respir Med, vol. 144, pp. 1-6, 2018.
C. L. Burton, Chen, Y., Chesterton, L. S., and van der Windt, D. A., “Trends in the prevalence, incidence and surgical management of carpal tunnel syndrome between 1993 and 2013: an observational analysis of UK primary care records”, BMJ Open, vol. 8, p. e020166, 2018.
E. Crellin, Mansfield, K. E., Leyrat, C., Nitsch, D., Douglas, I. J., Root, A., Williamson, E., Smeeth, L., and Tomlinson, L. A., “Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study”, Bmj, vol. 360, p. k341, 2018.
2017
J. Sarginson, Webb, R. T., Stocks, S. J., Esmail, A., Garg, S., and Ashcroft, D. M., “Temporal trends in antidepressant prescribing to children in UK primary care, 2000-2015”, J Affect Disord, vol. 210, pp. 312-318, 2017.
D. A. Lane, Skjoth, F., Lip, G. Y. H., Larsen, T. B., and Kotecha, D., “Temporal Trends in Incidence, Prevalence, and Mortality of Atrial Fibrillation in Primary Care”, J Am Heart Assoc, vol. 6, 2017.
S. Tomkins, Chapman, C., Myland, M., Tham, R., de Nobrega, R., Jackson, B., and Keshav, S., “Treating iron deficiency in patients with gastrointestinal disease: Risk of re-attendance in secondary care”, PLoS One, vol. 12, p. e0189952, 2017.
S. J. Sinnott, Smeeth, L., Williamson, E., and Douglas, I. J., “Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015”, Bmj, vol. 358, p. j3984, 2017.
H. K. Bronsveld, Peeters, P., de Groot, M. C. H., de Boer, A., Schmidt, M. K., and De Bruin, M. L., “Trends in breast cancer incidence among women with type-2 diabetes in British general practice”, Prim Care Diabetes, vol. 11, pp. 373-382, 2017.
K. Donegan, Fox, N., Black, N., Livingston, G., Banerjee, S., and Burns, A., “Trends in diagnosis and treatment for people with dementia in the UK from 2005 to 2015: a longitudinal retrospective cohort study”, Lancet Public Health, vol. 2, pp. e149-e156, 2017.
A. Taqi, Otete, H., and Knaggs, R. D., “Trends in opioid prescribing in primary care patients with knee osteoarthritis: A population based observational study”, Value in Health, vol. 20, pp. A540-A541, 2017.
R. Y. van der Velde, Wyers, C. E., Teesselink, E., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., Harvey, N. C., and van Staa, T. P., “Trends in oral anti-osteoporosis drug prescription in the United Kingdom between 1990 and 2012: Variation by age, sex, geographic location and ethnicity”, Bone, vol. 94, pp. 50-55, 2017.
J. L. Walker, Andrews, N. J., Mathur, R., Smeeth, L., and Thomas, S. L., “Trends in the burden of varicella in UK general practice”, Epidemiol Infect, vol. 145, pp. 2678-2682, 2017.
S. M. Collin, Bakken, I. J., Nazareth, I., Crawley, E., and White, P. D., “Trends in the incidence of chronic fatigue syndrome and fibromyalgia in the UK, 2001-2013: a Clinical Practice Research Datalink study”, J R Soc Med, vol. 110, pp. 231-244, 2017.
S. Y. Loo, Dell'Aniello, S., Huiart, L., and Renoux, C., “Trends in the prescription of novel oral anticoagulants in UK primary care”, Br J Clin Pharmacol, vol. 83, pp. 2096-2106, 2017.
2016
M. Pang, Schuster, T., Filion, K. B., Eberg, M., and Platt, R. W., “Targeted Maximum Likelihood Estimation for Pharmacoepidemiologic Research”, Epidemiology, vol. 27, pp. 570-7, 2016.
C. Martinez, Suissa, S., Rietbrock, S., Katholing, A., Freedman, B., Cohen, A. T., and Handelsman, D. J., “Testosterone treatment and risk of venous thromboembolism: population based case-control study”, Bmj, vol. 355, p. i5968, 2016.
E. Herrett, Williamson, E., Van Staa, T., Ranopa, M., Free, C., Chadborn, T., Goldacre, B., and Smeeth, L., “Text messaging reminders for influenza vaccine in primary care: a cluster randomised controlled trial (TXT4FLUJAB)”, BMJ Open, vol. 6, p. e010069, 2016.
C. Martinez, Katholing, A., Wallenhorst, C., and Freedman, S. B., “Therapy persistence in newly diagnosed non-valvular atrial fibrillation treated with warfarin or NOAC. A cohort study”, Thromb Haemost, vol. 115, pp. 31-9, 2016.
I. M. Carey, Anderson, H. R., Atkinson, R. W., Beevers, S., Cook, D. G., Dajnak, D., Gulliver, J., and Kelly, F. J., “Traffic pollution and the incidence of cardiorespiratory outcomes in an adult cohort in London”, Occup Environ Med, vol. 73, pp. 849-856, 2016.
J. Bedson, Chen, Y., Hayward, R. A., Ashworth, J., Walters, K., Dunn, K. M., and Jordan, K. P., “Trends in long-term opioid prescribing in primary care patients with musculoskeletal conditions: an observational database study”, Pain, vol. 157, pp. 1525-31, 2016.
N. Frey, Hugle, T., Jick, S. S., Meier, C. R., and Spoendlin, J., “Type II diabetes mellitus and incident osteoarthritis of the hand: a population-based case-control analysis”, Osteoarthritis Cartilage, vol. 24, pp. 1535-40, 2016.
2015
E. Koshy, Watt, H., Curcin, V., Bottle, A., Sharland, M., and Saxena, S., “Tonsillectomy among children with low baseline acute throat infection consultation rates in UK general practices: a cohort study”, BMJ Open, vol. 5, p. e006686, 2015.
J. P. Fournier, Yin, H., Nessim, S. J., Montastruc, J. L., and Azoulay, L., “Tramadol for noncancer pain and the risk of hyponatremia”, Am J Med, vol. 128, pp. 418-25.e5, 2015.
J. P. Fournier, Azoulay, L., Yin, H., Montastruc, J. L., and Suissa, S., “Tramadol use and the risk of hospitalization for hypoglycemia in patients with noncancer pain”, JAMA Intern Med, vol. 175, pp. 186-93, 2015.
A. M. Pfeil, Imfeld, P., Pettengell, R., Jick, S. S., Szucs, T. D., Meier, C. R., and Schwenkglenks, M., “Trends in incidence and medical resource utilisation in patients with chronic lymphocytic leukaemia: insights from the UK Clinical Practice Research Datalink (CPRD)”, Ann Hematol, vol. 94, pp. 421-9, 2015.
2014
K. E. Wurst, Punekar, Y. S., and Shukla, A., “Treatment evolution after COPD diagnosis in the UK primary care setting”, PLoS One, vol. 9, p. e105296, 2014.
P. N. Taylor, Minassian, C., Rehman, A., Iqbal, A., Draman, M. S., Hamilton, W., Dunlop, D., Robinson, A., Vaidya, B., Lazarus, J. H., Thomas, S., Dayan, C. M., and Okosieme, O. E., “TSH levels and risk of miscarriage in women on long-term levothyroxine: a community-based study”, J Clin Endocrinol Metab, vol. 99, pp. 3895-902, 2014.
L. Bensimon, Yin, H., Suissa, S., Pollak, M. N., and Azoulay, L., “Type 2 diabetes and the risk of mortality among patients with prostate cancer”, Cancer Causes Control, vol. 25, pp. 329-38, 2014.
[Page last reviewed 4 October 2019]