Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 4 March 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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 (PDF, 3MB, 220 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website. 

 

 

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2021
S. Swain, Coupland, C., Mallen, C., Kuo, C. F., Sarmanova, A., Bierma-Zeinstra, S. M. A., Englund, M., Prieto-Alhambra, D., Doherty, M., and Zhang, W., “Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting”, Rheumatology (Oxford), 2021.
A. Rahman, Kane, J., Montastruc, F., and Renoux, C., “Trends in new prescription of gabapentinoids and of coprescription with opioids in the 4 nations of the UK, 1993-2017”, Br J Clin Pharmacol, 2021.
J. Pearson-Stuttard, Bennett, J., Cheng, Y. J., Vamos, E. P., Cross, A. J., Ezzati, M., and Gregg, E. W., “Trends in predominant causes of death in individuals with and without diabetes in England from 2001 to 2018: an epidemiological analysis of linked primary care records”, Lancet Diabetes Endocrinol, vol. 9, pp. 165-173, 2021.
2020
J. Zhu and Gallego, B., “Targeted estimation of heterogeneous treatment effect in observational survival analysis”, J Biomed Inform, vol. 107, p. 103474, 2020.
S. C. Mendonca, Saunders, C. L., Lund, J., Mant, J., and Edwards, D., “Temporal trends in incidence of atrial fibrillation in primary care records: a population-based cohort study”, BMJ Open, vol. 10, p. e042518, 2020.
E. L. Axson, Sundaram, V., Bloom, C. I., Bottle, A., Cowie, M. R., and Quint, J. K., “Temporal Trends in the Incidence of Heart Failure among Patients with COPD and Its Association with Mortality”, Ann Am Thorac Soc, 2020.
M. Jani, B. Yimer, B., Sheppard, T., Lunt, M., and Dixon, W. G., “Time trends and prescribing patterns of opioid drugs in UK primary care patients with non-cancer pain: A retrospective cohort study”, PLoS Med, vol. 17, p. e1003270, 2020.
P. Planell-Morell, Bajekal, M., Denaxas, S., Raine, R., and Alexander, D. C., “Trajectories of Disease Accumulation Using Electronic Health Records”, Stud Health Technol Inform, vol. 270, pp. 469-473, 2020.
D. C. Gibbons, Aggarwal, B., Fairburn-Beech, J., Hinds, D., Fletcher, M., Bosnic-Anticevich, S., and Price, D., “Treatment patterns among non-active users of maintenance asthma medication in the United Kingdom: a retrospective cohort study in the Clinical Practice Research Datalink”, J Asthma, pp. 1-12, 2020.
D. Abrahami, McDonald, E. G., Schnitzer, M., and Azoulay, L., “Trends in acid suppressant drug prescriptions in primary care in the UK: a population-based cross-sectional study”, BMJ Open, vol. 10, p. e041529, 2020.
J. Ruzangi, Blair, M., Cecil, E., Greenfield, G., Bottle, A., Hargreaves, D. S., and Saxena, S., “Trends in healthcare use in children aged less than 15 years: a population-based cohort study in England from 2007 to 2017”, BMJ Open, vol. 10, p. e033761, 2020.
S. Swain, Sarmanova, A., Mallen, C., Kuo, C. F., Coupland, C., Doherty, M., and Zhang, W., “Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD)”, Osteoarthritis Cartilage, 2020.
H. T. Ayele, Reynier, P., Azoulay, L., Platt, R. W., Cabaussel, J., Benayoun, S., and Filion, K. B., “Trends in the pharmacological treatment of benign prostatic hyperplasia in the UK from 1998 to 2016: a population-based cohort study”, World J Urol, 2020.
S. Price, Spencer, A., Zhang, X., Ball, S., Lyratzopoulos, G., Mujica-Mota, R., Stapley, S., Ukoumunne, O. C., and Hamilton, W., “Trends in time to cancer diagnosis around the period of changing national guidance on referral of symptomatic patients: A serial cross-sectional study using UK electronic healthcare records from 2006-17”, Cancer Epidemiol, vol. 69, p. 101805, 2020.
2019
N. Conrad, Judge, A., Canoy, D., Tran, J., Pinho-Gomes, A. C., Millett, E. R. C., Salimi-Khorshidi, G., Cleland, J. G., McMurray, J. J. V., and Rahimi, K., “Temporal Trends and Patterns in Mortality After Incident Heart Failure: A Longitudinal Analysis of 86000 Individuals”, JAMA Cardiol, 2019.
D. Spanopoulos, Okhai, H., Zaccardi, F., Tebboth, A., Barrett, B., Busse, M., Webb, J., and Khunti, K., “Temporal variation of renal function in people with type 2 diabetes mellitus: a retrospective UK Clinical Practice Research Datalink cohort study”, Diabetes Obes Metab, 2019.
C. Santella, Renoux, C., Yin, H., Yu, O. H. Y., and Azoulay, L., “Testosterone Replacement Therapy and the Risk of Prostate Cancer in Men with Late-Onset Hypogonadism”, Am J Epidemiol, 2019.
J. M. Dennis, Henley, W. E., McGovern, A. P., Farmer, A. J., Sattar, N., Holman, R. R., Pearson, E. R., Hattersley, A. T., Shields, B. M., and Jones, A. G., “Time trends in prescribing of type 2 diabetes drugs, glycemic response and risk factors: a retrospective analysis of primary care data, 2010-2017”, Diabetes Obes Metab, 2019.
C. J. Czoski Murray, Kingsbury, S. R., Arden, N. K., Hewison, J., Judge, A., Matu, J., O'Shea, J., Pinedo-Villanueva, R., Smith, L. K., Smith, C., Thomas, C. M., West, R. M., Wright, J. M., Conaghan, P. G., and Stone, M. H., “Towards UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): protocol for an evaluation of the requirements for arthroplasty follow-up, and the production of consensus-based recommendations”, BMJ Open, vol. 9, p. e031351, 2019.
J. L. Rees, Shah, A., Edwards, K., Sanchez-Santos, M. T., Robinson, D. E., Delmestri, A., Carr, A., Arden, N., Lamb, S. E., Rangan, A., Judge, A., Pinedo-Villanueva, R., Holt, T., Hopewell, S., Prieto-Alhambra, D., and Collins, G., “Treatment of first-time traumatic anterior shoulder dislocation: the UK TASH-D cohort study”, Health Technol Assess, vol. 23, pp. 1-104, 2019.
D. Dedman, Coton, S. J., Ghosh, R. E., Meeraus, W., Crim, C., Harvey, C., Amelio, J., and Landis, S. H., “Treatment Patterns of New Users of Fluticasone Furoate/Vilanterol in Asthma and COPD in UK Primary Care: Retrospective Cohort Study”, Pulmonary Therapy, vol. 5, pp. 81-95, 2019.
G. Powell, Logan, J., Kiri, V., and Borghs, S., “Trends in antiepileptic drug treatment and effectiveness in clinical practice in England from 2003 to 2016: a retrospective cohort study using electronic medical records”, BMJ Open, vol. 9, p. e032551, 2019.
T. Appleyard, Ashworth, J., Bedson, J., Yu, D., and Peat, G., “Trends in gabapentinoid prescribing in patients with osteoarthritis: a United Kingdom national cohort study in primary care”, Osteoarthritis Cartilage, 2019.
M. Gompels, Michael, S., Davies, C., Jones, T., Macleod, J., and May, M., “Trends in HIV testing in the UK primary care setting: a 15-year retrospective cohort study from 2000 to 2015”, BMJ Open, vol. 9, p. e027744, 2019.
B. Feakins, Oke, J., McFadden, E., Aronson, J., Lasserson, D., O'Callaghan, C., Taylor, C., Hill, N., Stevens, R., and Perera, R., “Trends in kidney function testing in UK primary care since the introduction of the quality and outcomes framework: a retrospective cohort study using CPRD”, BMJ Open, vol. 9, p. e028062, 2019.
C. J. Taylor, Ordonez-Mena, J. M., Roalfe, A. K., Lay-Flurrie, S., Jones, N. R., Marshall, T., and Hobbs, F. D. R., “Trends in survival after a diagnosis of heart failure in the United Kingdom 2000-2017: population based cohort study”, Bmj, vol. 364, p. l223, 2019.
C. Group on H. Cancer, “Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence”, Lancet, vol. 394, pp. 1159-1168, 2019.
2018
N. Conrad, Judge, A., Tran, J., Mohseni, H., Hedgecott, D., Crespillo, A. P., Allison, M., Hemingway, H., Cleland, J. G., McMurray, J. J. V., and Rahimi, K., “Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals”, Lancet, vol. 391, pp. 572-580, 2018.
J. W. O'Sullivan, Stevens, S., Hobbs, F. D. R., Salisbury, C., Little, P., Goldacre, B., Bankhead, C., Aronson, J. K., Perera, R., and Heneghan, C., “Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests”, Bmj, vol. 363, p. k4666, 2018.
C. Martinez, Katholing, A., Folkerts, K., and Rietbrock, S., “Thirteen-year trend in the persistence with vitamin K antagonists for venous thromboembolism in the UK: a cohort study”, Curr Med Res Opin, vol. 34, pp. 1985-1990, 2018.
S. C. Chung, Pujades-Rodriguez, M., Duyx, B., Denaxas, S. C., Pasea, L., Hingorani, A., Timmis, A., Williams, B., and Hemingway, H., “Time spent at blood pressure target and the risk of death and cardiovascular diseases”, PLoS One, vol. 13, p. e0202359, 2018.
U. Desai, Kirson, N. Y., Kim, J., Khunti, K., King, S., Trieschman, E., Hellstern, M., Hunt, P. R., and Mukherjee, J., “Time to Treatment Intensification After Monotherapy Failure and Its Association With Subsequent Glycemic Control Among 93,515 Patients With Type 2 Diabetes”, Diabetes Care, vol. 41, pp. 2096-2104, 2018.
H. J. Curtis, Dennis, J. M., Shields, B. M., Walker, A. J., Bacon, S., Hattersley, A. T., Jones, A. G., and Goldacre, B., “Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017”, Diabetes Obes Metab, vol. 20, pp. 2159-2168, 2018.
S. M. Grandi, Reynier, P., Platt, R. W., Basso, O., and Filion, K. B., “The timing of onset of hypertensive disorders in pregnancy and the risk of incident hypertension and cardiovascular disease”, Int J Cardiol, vol. 270, pp. 273-275, 2018.
J. A. Hirst, Farmer, A. J., Smith, M. C., and Stevens, R. J., “Timings for HbA1c testing in people with diabetes are associated with incentive payments: an analysis of UK primary care data”, Diabet Med, 2018.
J. Charlton, Ravindrarajah, R., Hamada, S., Jackson, S. H., and Gulliford, M. C., “Trajectory of Total Cholesterol in the Last Years of Life Over Age 80 Years: Cohort Study of 99,758 Participants”, J Gerontol A Biol Sci Med Sci, vol. 73, pp. 1083-1089, 2018.
J. Gordon, McEwan, P., Idris, I., Evans, M., and Puelles, J., “Treatment choice, medication adherence and glycemic efficacy in people with type 2 diabetes: a UK clinical practice database study”, BMJ Open Diabetes Res Care, vol. 6, p. e000512, 2018.
I. Idris, Peng, X., He, X., Liu, D., Balogh, E., Kaushik, P., and van Brunt, K., “The Trend of High-Dose Insulin Usage Among Patients with Diabetes in the UK: A Retrospective Study”, Diabetes Ther, vol. 9, pp. 2245-2257, 2018.
E. Burn, Edwards, C. J., Murray, D. W., Silman, A., Cooper, C., Arden, N. K., Pinedo-Villanueva, R., and Prieto-Alhambra, D., “Trends and determinants of length of stay and hospital reimbursement following knee and hip replacement: evidence from linked primary care and NHS hospital records from 1997 to 2014”, BMJ Open, vol. 8, p. e019146, 2018.
V. W. Zhong, Juhaeri, J., and Mayer-Davis, E. J., “Trends in Hospital Admission for Diabetic Ketoacidosis in Adults With Type 1 and Type 2 Diabetes in England, 1998-2013: A Retrospective Cohort Study”, Diabetes Care, vol. 41, pp. 1870-1877, 2018.
O. A. Oshagbemi, Keene, S. J., Driessen, J. H. M., Jordan, R., Wouters, E. F. M., de Boer, A., de Vries, F., and Franssen, F. M. E., “Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013”, Respir Med, vol. 144, pp. 1-6, 2018.
C. L. Burton, Chen, Y., Chesterton, L. S., and van der Windt, D. A., “Trends in the prevalence, incidence and surgical management of carpal tunnel syndrome between 1993 and 2013: an observational analysis of UK primary care records”, BMJ Open, vol. 8, p. e020166, 2018.
E. Crellin, Mansfield, K. E., Leyrat, C., Nitsch, D., Douglas, I. J., Root, A., Williamson, E., Smeeth, L., and Tomlinson, L. A., “Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study”, Bmj, vol. 360, p. k341, 2018.
2017
J. Sarginson, Webb, R. T., Stocks, S. J., Esmail, A., Garg, S., and Ashcroft, D. M., “Temporal trends in antidepressant prescribing to children in UK primary care, 2000-2015”, J Affect Disord, vol. 210, pp. 312-318, 2017.
D. A. Lane, Skjoth, F., Lip, G. Y. H., Larsen, T. B., and Kotecha, D., “Temporal Trends in Incidence, Prevalence, and Mortality of Atrial Fibrillation in Primary Care”, J Am Heart Assoc, vol. 6, 2017.
S. Tomkins, Chapman, C., Myland, M., Tham, R., de Nobrega, R., Jackson, B., and Keshav, S., “Treating iron deficiency in patients with gastrointestinal disease: Risk of re-attendance in secondary care”, PLoS One, vol. 12, p. e0189952, 2017.
S. J. Sinnott, Smeeth, L., Williamson, E., and Douglas, I. J., “Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015”, Bmj, vol. 358, p. j3984, 2017.
H. K. Bronsveld, Peeters, P., de Groot, M. C. H., de Boer, A., Schmidt, M. K., and De Bruin, M. L., “Trends in breast cancer incidence among women with type-2 diabetes in British general practice”, Prim Care Diabetes, vol. 11, pp. 373-382, 2017.
K. Donegan, Fox, N., Black, N., Livingston, G., Banerjee, S., and Burns, A., “Trends in diagnosis and treatment for people with dementia in the UK from 2005 to 2015: a longitudinal retrospective cohort study”, Lancet Public Health, vol. 2, pp. e149-e156, 2017.
A. Taqi, Otete, H., and Knaggs, R. D., “Trends in opioid prescribing in primary care patients with knee osteoarthritis: A population based observational study”, Value in Health, vol. 20, pp. A540-A541, 2017.
[Page last reviewed 4 March 2021]