Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,200 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 5 August 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
A. Pate, Emsley, R., Ashcroft, D. M., Brown, B., and Van Staa, T., The uncertainty with using risk prediction models for individual decision making: an exemplar cohort study examining the prediction of cardiovascular disease in English primary care, BMC Med, vol. 17, p. 134, 2019.
C. Rebordosa, Aguado, J., Plana, E., Thomas, S., Frances, A., Lei, A., Garcia-Gil, E., Nuevo, J., Perez-Gutthann, S., and Castellsague, J., Use of aclidinium did not increase the risk of death in a noninterventional cohort study in the Clinical Practice Research Datalink (CPRD), United Kingdom, Respir Med, vol. 152, pp. 37-43, 2019.
Y. Vinogradova, Coupland, C., and Hippisley-Cox, J., Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases, Bmj, vol. 364, p. k4810, 2019.
J. Watson, Jones, H. E., Banks, J., Whiting, P., Salisbury, C., and Hamilton, W., Use of multiple inflammatory marker tests in primary care: using Clinical Practice Research Datalink to evaluate accuracy, Br J Gen Pract, vol. 69, pp. e462-e469, 2019.
A. Tran-Duy, Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F., and de Boer, A., Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study, J Intern Med, vol. 285, pp. 205-214, 2019.
T. Burkard, Moser, M., Rauch, M., Jick, S. S., and Meier, C. R., Utilization pattern of hormone therapy in UK general practice between 1996 and 2015: a descriptive study, Menopause, 2019.
2018
L. McDonald, Sammon, C. J., Samnaliev, M., and Ramagopalan, S., Under-recording of hospital bleeding events in UK primary care: a linked Clinical Practice Research Datalink and Hospital Episode Statistics study, Clin Epidemiol, vol. 10, pp. 1155-1168, 2018.
D. Yu, Jordan, K. P., and Peat, G., Underrecording of osteoarthritis in United Kingdom primary care electronic health record data, Clin Epidemiol, vol. 10, pp. 1195-1201, 2018.
F. Ahmadizar, Souverein, P., de Boer, A., and van der Zee, A. H. Maitlan, Undertreatment of hypertension and hypercholesterolaemia in children and adolescents with type 1 diabetes: long-term follow-up on time trends in the occurrence of cardiovascular disease, risk factors and medications use, Br J Clin Pharmacol, vol. 84, pp. 776-785, 2018.
C. F. Kuo, Chou, I. J., See, L. C., Chen, J. S., Yu, K. H., Luo, S. F., Hsieh, A. H., Zhang, W., and Doherty, M., Urate-lowering treatment and risk of total joint replacement in patients with gout, Rheumatology (Oxford), vol. 57, pp. 2129-2139, 2018.
A. Douros, Abrahami, D., Yin, H., Yu, O. H. Y., Renoux, C., Hudson, M., and Azoulay, L., Use of Dipeptidyl Peptidase-4 Inhibitors and New-onset Rheumatoid Arthritis in Patients with Type 2 Diabetes, Epidemiology, vol. 29, pp. 904-912, 2018.
A. Keyany, Nielen, J. T. H., Souverein, P. C., de Vries, F., and van den Bemt, B., Use of parenteral glucocorticoids and the risk of new onset type 2 diabetes mellitus: A case-control study, Diabetes Res Clin Pract, vol. 139, pp. 100-106, 2018.
P. Tammes, Sartini, C., Preston, I., Hay, A. D., Lasserson, D., and Morris, R. W., Use of primary care data to predict those most vulnerable to cold weather: a case-crossover analysis, Br J Gen Pract, vol. 68, pp. e146-e156, 2018.
A. Tran-Duy, Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F., and de Boer, A., Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study, J Intern Med, 2018.
J. G. Kuiper, van Herk-Sukel, M. P. P., Castellsague, J., Pottegard, A., Berglind, I. A., Dedman, D., Gutierrez, L., Calingaert, B., Hallas, J., Sundstrom, A., Gallagher, A. M., Kaye, J. A., Pardo, C., Rothman, K. J., and Perez-Gutthann, S., Use of Topical Tacrolimus and Topical Pimecrolimus in Four European Countries: A Multicentre Database Cohort Study, Drugs Real World Outcomes, 2018.
S. S. Zghebi, Rutter, M. K., Ashcroft, D. M., Salisbury, C., Mallen, C., Chew-Graham, C. A., Reeves, D., van Marwijk, H., Qureshi, N., Weng, S., Peek, N., Planner, C., Nowakowska, M., Mamas, M., and Kontopantelis, E., Using electronic health records to quantify and stratify the severity of type 2 diabetes in primary care in England: rationale and cohort study design, BMJ Open, vol. 8, p. e020926, 2018.
S. L. Stevens, McManus, R. J., and Stevens, R. J., The utility of long-term blood pressure variability for cardiovascular risk prediction in primary care, J Hypertens, 2018.
2017
F. X. Lamy, Saragoussi, D., Johnson, M. E., Guiraud-Diawara, A., Jorgensen, K. T., Loze, J. Y., and Maguire, A., The use of adjunctive antipsychotics to treat depression in UK primary care, Curr Med Res Opin, vol. 33, pp. 891-898, 2017.
V. Mandilaras, Bouganim, N., Yin, H., Asselah, J., and Azoulay, L., The use of drugs acting on the renin-angiotensin system and the incidence of pancreatic cancer, Br J Cancer, vol. 116, pp. 103-108, 2017.
L. M. Knapen, de Jong, R. G., Driessen, J. H., Keulemans, Y. C., van Erp, N. P., De Bruin, M. L., Leufkens, H. G., Croes, S., and de Vries, F., Use of incretin agents and risk of acute and chronic pancreatitis: A population-based cohort study, Diabetes Obes Metab, vol. 19, pp. 401-411, 2017.
J. Gorricho, Garjon, J., Alonso, A., Celaya, M. C., Saiz, L. C., Erviti, J., and Lopez, A., Use of oral antidiabetic agents and risk of community-acquired pneumonia: a nested case-control study, Br J Clin Pharmacol, vol. 83, pp. 2034-2044, 2017.
T. A. Durham, K. Lich, H., Viera, A. J., Fine, J. P., Mukherjee, J., Weinberger, M., and Dusetzina, S. B., Utilization of Standard and Target-Specific Oral Anticoagulants Among Adults in the United Kingdom With Incident Atrial Fibrillation, Am J Cardiol, vol. 120, pp. 1820-1829, 2017.
2016
R. Joshi, Venkatesan, S., and Myles, P. R., A UK general practice population cohort study investigating the association between lipid lowering drugs and 30-day mortality following medically attended acute respiratory illness, PeerJ, vol. 4, p. e1902, 2016.
N. A. Francis, Hood, K., Lyons, R., and Butler, C. C., Understanding flucloxacillin prescribing trends and treatment non-response in UK primary care: a Clinical Practice Research Datalink (CPRD) study, J Antimicrob Chemother, vol. 71, pp. 2037-46, 2016.
S. Rajaram, Steffey, A., Blak, B., Hickman, M., Christensen, H., and Caspard, H., Uptake of childhood influenza vaccine from 2012-2013 to 2014-2015 in the UK and the implications for high-risk children: a retrospective observational cohort study, BMJ Open, vol. 6, p. e010625, 2016.
C. J. Crooks, Card, T. R., and West, J., The Use of a Bayesian Hierarchy to Develop and Validate a Co-Morbidity Score to Predict Mortality for Linked Primary and Secondary Care Data from the NHS in England, PLoS One, vol. 11, p. e0165507, 2016.
L. Azoulay, Soldera, S., Yin, H., and Bouganim, N., Use of Calcium Channel Blockers and Risk of Breast Cancer: A Population-based Cohort Study, Epidemiology, vol. 27, pp. 594-601, 2016.
C. Seliger, Meier, C. R., Jick, S. S., Uhl, M., Bogdahn, U., Hau, P., and Leitzmann, M. F., Use of cardiac glycosides and risk of glioma, J Neurooncol, vol. 127, pp. 321-8, 2016.
L. M. Knapen, van Dalem, J., Keulemans, Y. C., van Erp, N. P., Bazelier, M. T., De Bruin, M. L., Leufkens, H. G., Croes, S., Neef, C., de Vries, F., and Driessen, J. H., Use of incretin agents and risk of pancreatic cancer: a population-based cohort study, Diabetes Obes Metab, vol. 18, pp. 258-65, 2016.
C. Seliger, Meier, C. R., Becker, C., Jick, S. S., Bogdahn, U., Hau, P., and Leitzmann, M. F., Use of Selective Cyclooxygenase-2 Inhibitors, Other Analgesics, and Risk of Glioma, PLoS One, vol. 11, p. e0149293, 2016.
K. Tascilar, Azoulay, L., Dell'Aniello, S., Bartels, D. B., and Suissa, S., The Use of Telmisartan and the Incidence of Cancer, Am J Hypertens, vol. 29, pp. 1358-1365, 2016.
J. T. Nielen, de Vries, F., Dagnelie, P. C., van den Bemt, B. J., Emans, P. J., Lalmohamed, A., de Boer, A., and Boonen, A., Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case-control study, Br J Clin Pharmacol, vol. 81, pp. 370-8, 2016.
M. Asaria, Walker, S., Palmer, S., Gale, C. P., Shah, A. D., Abrams, K. R., Crowther, M., Manca, A., Timmis, A., Hemingway, H., and Sculpher, M., Using electronic health records to predict costs and outcomes in stable coronary artery disease, Heart, vol. 102, pp. 755-62, 2016.
2015
F. Lapi, Azoulay, L., Kezouh, A., Benisty, J., Matok, I., Mugelli, A., and Suissa, S., The use of antidepressants and the risk of chronic atrial fibrillation, J Clin Pharmacol, vol. 55, pp. 423-30, 2015.
J. Assayag, Pollak, M. N., and Azoulay, L., The use of aspirin and the risk of mortality in patients with prostate cancer, J Urol, vol. 193, pp. 1220-5, 2015.
Y. Vinogradova, Coupland, C., and Hippisley-Cox, J., Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases, Bmj, vol. 350, p. h2135, 2015.
D. M. Carbonari, Saine, M. E., Newcomb, C. W., Blak, B., Roy, J. A., Haynes, K., Wood, J., Gallagher, A. M., Bhullar, H., Cardillo, S., Hennessy, S., Strom, B. L., and , Use of demographic and pharmacy data to identify patients included within both the Clinical Practice Research Datalink (CPRD) and The Health Improvement Network (THIN), Pharmacoepidemiol Drug Saf, vol. 24, pp. 999-1003, 2015.
W. R. der Zanden, de Vries, F., Lalmohamed, A., Driessen, J. H., de Boer, A., Rohde, G., Neef, C., and C. Heijer, den, Use of Dipeptidyl-Peptidase-4 Inhibitors and the Risk of Pneumonia: A Population-Based Cohort Study, PLoS One, vol. 10, p. e0139367, 2015.
M. Tuccori, Wu, J. W., Yin, H., Majdan, A., and Azoulay, L., The Use of Glyburide Compared With Other Sulfonylureas and the Risk of Cancer in Patients With Type 2 Diabetes, Diabetes Care, vol. 38, pp. 2083-9, 2015.
2013
N. M. Hawkins, Scholes, S., Bajekal, M., Love, H., O'Flaherty, M., Raine, R., and Capewell, S., The UK National Health Service: delivering equitable treatment across the spectrum of coronary disease, Circ Cardiovasc Qual Outcomes, vol. 6, pp. 208-16, 2013.
E. Hak, Mulder, B., Schuiling-Veninga, C. C., de Vries, T. W., and Jick, S. S., Use of acid-suppressive drugs in pregnancy and the risk of childhood asthma: bidirectional crossover study using the general practice research database, Drug Saf, vol. 36, pp. 1097-104, 2013.
L. A. Garcia Rodriguez, Johansson, S., and L. Soriano, C., Use of clopidogrel and proton pump inhibitors after a serious acute coronary event: risk of coronary events and peptic ulcer bleeding, Thromb Haemost, vol. 110, pp. 1014-24, 2013.
L. L. Lanza, McQuay, L. J., Rothman, K. J., Bone, H. G., Kaunitz, A. M., Harel, Z., Ataher, Q., Ross, D., Arena, P. L., and Wolter, K. D., Use of depot medroxyprogesterone acetate contraception and incidence of bone fracture, Obstet Gynecol, vol. 121, pp. 593-600, 2013.
C. R. Dormuth, Hemmelgarn, B. R., Paterson, J. M., James, M. T., Teare, G. F., Raymond, C. B., Lafrance, J. P., Levy, A., Garg, A. X., and Ernst, P., Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases, Bmj, vol. 346, p. f880, 2013.
B. Smiechowski, Azoulay, L., Yin, H., Pollak, M. N., and Suissa, S., The use of metformin and colorectal cancer incidence in patients with type II diabetes mellitus, Cancer Epidemiol Biomarkers Prev, vol. 22, pp. 1877-83, 2013.
B. B. Smiechowski, Azoulay, L., Yin, H., Pollak, M. N., and Suissa, S., The use of metformin and the incidence of lung cancer in patients with type 2 diabetes, Diabetes Care, vol. 36, pp. 124-9, 2013.
[Page last reviewed 5 August 2019]