Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,200 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 June 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


(PDF, 3MB, 183 pages)


Export 2252 results:
Author Title Type [ Year(Asc)]
M. Ardissino, Moussa, O., Tang, A., Muttoni, E., Ziprin, P., and Purkayastha, S., Idiopathic intracranial hypertension in the British population with obesity, Acta Neurochir (Wien), vol. 161, pp. 239-246, 2019.
N. Al-Attar, Johnston, S., Jamous, N., Mistry, S., Ghosh, E., Gangoli, G., Danker, W., Etter, K., and Ammann, E., Impact of bleeding complications on length of stay and critical care utilization in cardiac surgery patients in England, J Cardiothorac Surg, vol. 14, p. 64, 2019.
E. Burn, Edwards, C. J., Murray, D. W., Silman, A., Cooper, C., Arden, N. K., Prieto-Alhambra, D., and Pinedo-Villanueva, R., The impact of bmi and smoking on risk of revision following knee and hip replacement surgery: evidence from routinely collected data, Osteoarthritis Cartilage, 2019.
J. L. Atkins, Delgado, J., Pilling, L. C., Bowman, K., Masoli, J. A. H., Kuchel, G. A., Ferrucci, L., and Melzer, D., Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts, J Gerontol A Biol Sci Med Sci, vol. 74, pp. 350-357, 2019.
J. T. H. Nielen, Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., and de Vries, F., Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 148, pp. 240-248, 2019.
K. C. Chang, Vamos, E. P., Palladino, R., Majeed, A., Lee, J. T., and Millett, C., Impact of the NHS Health Check on inequalities in cardiovascular disease risk: a difference-in-differences matching analysis, J Epidemiol Community Health, vol. 73, pp. 11-18, 2019.
K. Davies, Johnson, E. L., Hollen, L., Jones, H. M., Lyttle, M. D., Maguire, S., and Kemp, A. M., Incidence of medically attended paediatric burns across the UK, Inj Prev, 2019.
N. E. O'Connell, Smith, K. J., Peterson, M. D., Ryan, N., Liverani, S., Anokye, N., Victor, C., and Ryan, J. M., Incidence of osteoarthritis, osteoporosis and inflammatory musculoskeletal diseases in adults with cerebral palsy: A population-based cohort study, Bone, vol. 125, pp. 30-35, 2019.
L. Wei, Lai, E. C., Kao-Yang, Y. H., Walker, B. R., MacDonald, T. M., and Andrew, R., Incidence of type 2 diabetes mellitus in men receiving steroid 5alpha-reductase inhibitors: population based cohort study, Bmj, vol. 365, p. l1204, 2019.
T. S. Field, Weijs, B., Curcio, A., Giustozzi, M., Sudikas, S., Katholing, A., Wallenhorst, C., Weitz, J. I., Cohen, A. T., and Martinez, C., Incident Atrial Fibrillation, Dementia and the Role of Anticoagulation: A Population-Based Cohort Study, Thromb Haemost, 2019.
H. Strongman, Williams, R., Meeraus, W., Murray-Thomas, T., Campbell, J., Carty, L., Dedman, D., Gallagher, A., Oyinlola, J., Kousoulis, A., and Valentine, J., Limitations for health research with restricted data collection from UK primary care, Pharmacoepidemiol Drug Saf, 2019.
E. Badrick, Renehan, I., and Renehan, A. G., Linkage of the UK Clinical Practice Research Datalink with the national cancer registry, Eur J Epidemiol, vol. 34, pp. 101-102, 2019.
M. Sabido, Thilo, H., and Guido, G., Long-term effectiveness of bisoprolol in patients with angina: A real-world evidence study, Pharmacol Res, vol. 139, pp. 106-112, 2019.
J. A. Rassen, Bartels, D. B., Schneeweiss, S., Patrick, A. R., and Murk, W., Measuring prevalence and incidence of chronic conditions in claims and electronic health record databases, Clin Epidemiol, vol. 11, pp. 1-15, 2019.
R. E. Farmer, Ford, D., Mathur, R., Chaturvedi, N., Kaplan, R., Smeeth, L., and Bhaskaran, K., Metformin use and risk of cancer in patients with type 2 diabetes: a cohort study of primary care records using inverse probability weighting of marginal structural models, Int J Epidemiol, 2019.
R. Brauer, Herrero-Zazo, M., Barlow, D. J., Gaughran, F., Taylor, D., and Howard, L. M., Minocycline and the risk of acute psychiatric events in adolescence: A self-controlled case series, J Psychopharmacol, p. 269881118821852, 2019.
J. M. Ryan, Peterson, M. D., Ryan, N., Smith, K. J., N, E. O. 'Connell, Liverani, S., Anokye, N., Victor, C., and Allen, E., Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy, Dev Med Child Neurol, 2019.
R. Persson, Lee, S., Yood, M. U., Wagner, M., Minton, N., Niemcryk, S., Lindholm, A., Evans, A., and Jick, S., Multi-database study of multiple sclerosis: identification, validation and description of MS patients in two countries, J Neurol, 2019.
G. Glover, Williams, R., Tompkins, G., and Oyinlola, J., An observational study of the use of acute hospital care by people with intellectual disabilities in England, J Intellect Disabil Res, vol. 63, pp. 85-99, 2019.
C. L. Morgan, Jenkins-Jones, S., Currie, C., and Baxter, G., Outcomes Associated with Treatment of Chronic Pain with Tapentadol Compared with Morphine and Oxycodone: A UK Primary Care Observational Study, Adv Ther, 2019.
R. Williams, Kothny, W., Serban, C., Lopez-Leon, S., and Schlienger, R., Pancreatic safety of vildagliptin in patients with type 2 diabetes mellitus: A European, noninterventional, postauthorization safety study, Endocrinol Diabetes Metab, vol. 2, p. e00052, 2019.
S. Lay-Flurrie, Mathieu, E., Bankhead, C., Nicholson, B. D., Perera-Salazar, R., Holt, T., Hobbs, F. D. R., and Salisbury, C., Patient consultation rate and clinical and NHS outcomes: a cross-sectional analysis of English primary care data from 2.7 million patients in 238 practices, BMC Health Serv Res, vol. 19, p. 219, 2019.
C. I. Bloom, Ricciardi, F., Smeeth, L., Stone, P., and Quint, J. K., Predicting COPD 1-year mortality using prognostic predictors routinely measured in primary care, BMC Med, vol. 17, p. 73, 2019.
S. F. Weng, Vaz, L., Qureshi, N., and Kai, J., Prediction of premature all-cause mortality: A prospective general population cohort study comparing machine-learning and standard epidemiological approaches, PLoS One, vol. 14, p. e0214365, 2019.
J. Watson, Salisbury, C., Banks, J., Whiting, P., and Hamilton, W., Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records, Br J Cancer, 2019.
S. Venkatesan, Jorgensen, M. E., Manning, H. J., Andersson, C., Mozid, A. M., Coburn, M., Moonesinghe, S. R., Foex, P., Mythen, M., Grocott, M. P. W., Hardman, J. G., Myles, P. R., and Sanders, R. D., Preoperative chronic beta-blocker prescription in elderly patients as a risk factor for postoperative mortality stratified by preoperative blood pressure: a cohort study, Br J Anaesth, 2019.
T. Newlove-Delgado, Hamilton, W., Ford, T. J., Stein, K., and Ukoumunne, O. C., Prescribing for young people with attention deficit hyperactivity disorder in UK primary care: analysis of data from the Clinical Practice Research Datalink, Atten Defic Hyperact Disord, 2019.
M. J. Carr, Ashcroft, D. M., White, P. D., Kapur, N., and Webb, R. T., Prevalence of comorbid mental and physical illnesses and risks for self-harm and premature death among primary care patients diagnosed with fatigue syndromes, Psychol Med, pp. 1-8, 2019.
V. W. Zhong, Juhaeri, J., Cole, S. R., Shay, C. M., Gordon-Larsen, P., Kontopantelis, E., and Mayer-Davis, E. J., Proximal HbA1C Level and First Hypoglycemia Hospitalization in Adults with Incident Type 2 Diabetes, J Clin Endocrinol Metab, 2019.
E. A. Shephard, Parkinson, M. A., and Hamilton, W. T., Recognising laryngeal cancer in primary care: a large case-control study using electronic records, Br J Gen Pract, vol. 69, pp. e127-e133, 2019.
Y. Li, Molter, A., White, A., Welfare, W., Palin, V., Belmonte, M., Ashcroft, D. M., Sperrin, M., and van Staa, T. P., Relationship between prescribing of antibiotics and other medicines in primary care: a cross-sectional study, Br J Gen Pract, vol. 69, pp. e42-e51, 2019.
S. V. Ramagopalan, Stamp, E., Sammon, C. J., Besford, M., Carroll, R., Mehmud, F., and Alikhan, R., Renal function and oral anticoagulant treatment of incident non-valvular atrial fibrillation: a retrospective study, Future Cardiol, 2019.
S. Weir, Kuo, T. C., Samnaliev, M., Tierney, T. S., Manca, A., Taylor, R. S., Bruce, J., Eldabe, S., and Cumming, D., Reoperation following lumbar spinal surgery: costs and outcomes in a UK population cohort study using the Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES), Eur Spine J, 2019.
T. Newlove-Delgado, Ford, T. J., Hamilton, W., Janssens, A., Stein, K., and Ukoumunne, O. C., Resumption of attention-deficit hyperactivity disorder medication in early adulthood: findings from a UK primary care prescribing study, Eur Child Adolesc Psychiatry, 2019.
E. L. Axson, Bual, N., Bloom, C. I., and Quint, J. K., Risk factors and secondary care utilisation in a primary care population with non-tuberculous mycobacterial disease in the UK, Eur J Clin Microbiol Infect Dis, vol. 38, pp. 117-124, 2019.
J. Bedson, Chen, Y., Ashworth, J., Hayward, R. A., Dunn, K. M., and Jordan, K. P., Risk of adverse events in patients prescribed long-term opioids: A cohort study in the UK Clinical Practice Research Datalink, Eur J Pain, 2019.
M. Blagojevic-Bucknall, Mallen, C., Muller, S., Hayward, R., West, S., Choi, H., and Roddy, E., The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study, Arthritis Rheumatol, vol. 71, pp. 154-160, 2019.
E. Williamson, Denaxas, S., Morris, S., Clarke, C. S., Thomas, M., Evans, H., Direk, K., Gonzalez-Izquierdo, A., Little, P., Lund, V., Blackshaw, H., Schilder, A., Philpott, C., Hopkins, C., and Carpenter, J., Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records, Rhinology, 2019.
F. Zaccardi, Husemoen, L. L. Nystrup, Thorsted, B. L., Webb, D. R., Paul, S. K., Davies, M. J., and Khunti, K., Selectivity of beta-blockers, cardiovascular and all-cause mortality in people with hypoglycaemia: An observational study, Nutr Metab Cardiovasc Dis, vol. 29, pp. 481-488, 2019.
C. Linde, Qin, L., Bakhai, A., Furuland, H., Evans, M., Ayoubkhani, D., Palaka, E., Bennett, H., and McEwan, P., Serum potassium and clinical outcomes in heart failure patients: results of risk calculations in 21 334 patients in the UK, ESC Heart Fail, 2019.
M. Weldegiorgis, Smith, M., Herrington, W. G., Bankhead, C., and Woodward, M., Socioeconomic disadvantage and the risk of advanced chronic kidney disease: results from a cohort study with 1.4 million participants, Nephrology Dialysis Transplantation, 2019.
M. S. Chan, van den Hout, A., Pujades-Rodriguez, M., Jones, M. M., Matthews, F. E., Jagger, C., Raine, R., and Bajekal, M., Socio-economic inequalities in life expectancy of older adults with and without multimorbidity: a record linkage study of 1.1 million people in England, Int J Epidemiol, 2019.
R. K. Akyea, Kai, J., Qureshi, N., Iyen, B., and Weng, S. F., Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease, Heart, 2019.
D. Spanopoulos, Okhai, H., Zaccardi, F., Tebboth, A., Barrett, B., Busse, M., Webb, J., and Khunti, K., Temporal variation of renal function in people with type 2 diabetes mellitus: a retrospective UK Clinical Practice Research Datalink cohort study, Diabetes Obes Metab, 2019.
C. Santella, Renoux, C., Yin, H., Yu, O. H. Y., and Azoulay, L., Testosterone Replacement Therapy and the Risk of Prostate Cancer in Men with Late-Onset Hypogonadism, Am J Epidemiol, 2019.
J. M. Dennis, Henley, W. E., McGovern, A. P., Farmer, A. J., Sattar, N., Holman, R. R., Pearson, E. R., Hattersley, A. T., Shields, B. M., and Jones, A. G., Time trends in prescribing of type 2 diabetes drugs, glycemic response and risk factors: a retrospective analysis of primary care data, 2010-2017, Diabetes Obes Metab, 2019.
J. A. Hirst, Farmer, A. J., Smith, M. C., and Stevens, R. J., Timings for HbA1c testing in people with diabetes are associated with incentive payments: an analysis of UK primary care data, Diabet Med, vol. 36, pp. 36-43, 2019.
J. L. Rees, Shah, A., Edwards, K., Sanchez-Santos, M. T., Robinson, D. E., Delmestri, A., Carr, A., Arden, N., Lamb, S. E., Rangan, A., Judge, A., Pinedo-Villanueva, R., Holt, T., Hopewell, S., Prieto-Alhambra, D., and Collins, G., Treatment of first-time traumatic anterior shoulder dislocation: the UK TASH-D cohort study, Health Technol Assess, vol. 23, pp. 1-104, 2019.
C. J. Taylor, Ordonez-Mena, J. M., Roalfe, A. K., Lay-Flurrie, S., Jones, N. R., Marshall, T., and Hobbs, F. D. R., Trends in survival after a diagnosis of heart failure in the United Kingdom 2000-2017: population based cohort study, Bmj, vol. 364, p. l223, 2019.
C. Rebordosa, Aguado, J., Plana, E., Thomas, S., Frances, A., Lei, A., Garcia-Gil, E., Nuevo, J., Perez-Gutthann, S., and Castellsague, J., Use of aclidinium did not increase the risk of death in a noninterventional cohort study in the Clinical Practice Research Datalink (CPRD), United Kingdom, Respir Med, vol. 152, pp. 37-43, 2019.
[Page last reviewed 6 June 2019]