Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 October 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
E. Williamson, Denaxas, S., Morris, S., Clarke, C. S., Thomas, M., Evans, H., Direk, K., Gonzalez-Izquierdo, A., Little, P., Lund, V., Blackshaw, H., Schilder, A., Philpott, C., Hopkins, C., and Carpenter, J., Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records, Rhinology, 2019.
C. Linde, Qin, L., Bakhai, A., Furuland, H., Evans, M., Ayoubkhani, D., Palaka, E., Bennett, H., and McEwan, P., Serum potassium and clinical outcomes in heart failure patients: results of risk calculations in 21 334 patients in the UK, ESC Heart Fail, 2019.
M. Rafiq, Hayward, A., Warren-Gash, C., Denaxas, S., Gonzalez-Izquierdo, A., Lyratzopoulos, G., and Thomas, S., Socioeconomic deprivation and regional variation in Hodgkin's lymphoma incidence in the UK: a population-based cohort study of 10 million individuals, BMJ Open, vol. 9, p. e029228, 2019.
J. Fortuny, Gilsenan, A., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Kollhorst, B., Karlsson, P., Linner, L., MacDonald, T. M., Plana, E., Ruigomez, A., Schink, T., Ziemiecki, R., and Andrews, E. B., Study Design and Cohort Comparability in a Study of Major Cardiovascular Events in New Users of Prucalopride Versus Polyethylene Glycol 3350, Drug Saf, 2019.
A. Banerjee, Allan, V., Denaxas, S., Shah, A., Kotecha, D., Lambiase, P. D., Jacob, J., Lund, L. H., and Hemingway, H., Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis, Europace, 2019.
A. Banerjee, Allan, V., Denaxas, S., Shah, A., Kotecha, D., Lambiase, P. D., Jacob, J., Lund, L. H., and Hemingway, H., Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis, Europace, 2019.
J. L. Rees, Shah, A., Edwards, K., Sanchez-Santos, M. T., Robinson, D. E., Delmestri, A., Carr, A., Arden, N., Lamb, S. E., Rangan, A., Judge, A., Pinedo-Villanueva, R., Holt, T., Hopewell, S., Prieto-Alhambra, D., and Collins, G., Treatment of first-time traumatic anterior shoulder dislocation: the UK TASH-D cohort study, Health Technol Assess, vol. 23, pp. 1-104, 2019.
B. Feakins, Oke, J., McFadden, E., Aronson, J., Lasserson, D., O'Callaghan, C., Taylor, C., Hill, N., Stevens, R., and Perera, R., Trends in kidney function testing in UK primary care since the introduction of the quality and outcomes framework: a retrospective cohort study using CPRD, BMJ Open, vol. 9, p. e028062, 2019.
C. J. Taylor, Ordonez-Mena, J. M., Roalfe, A. K., Lay-Flurrie, S., Jones, N. R., Marshall, T., and Hobbs, F. D. R., Trends in survival after a diagnosis of heart failure in the United Kingdom 2000-2017: population based cohort study, Bmj, vol. 364, p. l223, 2019.
S. Denaxas, Gonzalez-Izquierdo, A., Direk, K., Fitzpatrick, N. K., Fatemifar, G., Banerjee, A., Dobson, R. J. B., Howe, L. J., Kuan, V., Lumbers, R. T., Pasea, L., Patel, R. S., Shah, A. D., Hingorani, A. D., Sudlow, C., and Hemingway, H., UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER, J Am Med Inform Assoc, 2019.
C. Rebordosa, Aguado, J., Plana, E., Thomas, S., Frances, A., Lei, A., Garcia-Gil, E., Nuevo, J., Perez-Gutthann, S., and Castellsague, J., Use of aclidinium did not increase the risk of death in a noninterventional cohort study in the Clinical Practice Research Datalink (CPRD), United Kingdom, Respir Med, vol. 152, pp. 37-43, 2019.
2018
K. Richardson, Fox, C., Maidment, I., Steel, N., Loke, Y. K., Arthur, A., Myint, P. K., Grossi, C. M., Mattishent, K., Bennett, K., Campbell, N. L., Boustani, M., Robinson, L., Brayne, C., Matthews, F. E., and Savva, G. M., Anticholinergic drugs and risk of dementia: case-control study, Bmj, vol. 361, p. k1315, 2018.
K. Bhaskaran, dos-Santos-Silva, I., Leon, D. A., Douglas, I. J., and Smeeth, L., Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3.6 million adults in the UK, Lancet Diabetes Endocrinol, vol. 6, pp. 944-953, 2018.
S. R. Pye, Sheppard, T., Joseph, R. M., Lunt, M., Girard, N., Haas, J. S., Bates, D. W., Buckeridge, D. L., van Staa, T. P., Tamblyn, R., and Dixon, W. G., Assumptions made when preparing drug exposure data for analysis have an impact on results: An unreported step in pharmacoepidemiology studies, Pharmacoepidemiol Drug Saf, vol. 27, pp. 781-788, 2018.
K. W. Littink, Stappers, P. T. Y., Riemslag, F. C. C., Talsma, H. E., van Genderen, M. M., Cremers, F. P. M., Collin, R. W. J., and van den Born, L. I., Autosomal Recessive NRL Mutations in Patients with Enhanced S-Cone Syndrome, Genes (Basel), vol. 9, 2018.
F. A. Pearce, Hubbard, R. B., Grainge, M. J., Watts, R. A., Abhishek, A., and Lanyon, P. C., Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study, Qjm, vol. 111, pp. 39-45, 2018.
R. Williams, van Staa, T. P., Gallagher, A. M., Hammad, T., Leufkens, H. G. M., and de Vries, F., Cancer recording in patients with and without type 2 diabetes in the Clinical Practice Research Datalink primary care data and linked hospital admission data: a cohort study, BMJ Open, vol. 8, p. e020827, 2018.
L. Li, Neogi, T., and Jick, S., A cohort study of comorbidity in patients with granulomatosis with polyangiitis, Rheumatology (Oxford), vol. 57, pp. 291-299, 2018.
J. Busby, Murray, L., Mills, K., Zhang, S. D., Liberante, F., and Cardwell, C. R., A combined connectivity mapping and pharmacoepidemiology approach to identify existing medications with breast cancer causing or preventing properties, Pharmacoepidemiol Drug Saf, vol. 27, pp. 78-86, 2018.
S. Y. Loo, Coulombe, J., Dell'Aniello, S., Brophy, J. M., Suissa, S., and Renoux, C., Comparative effectiveness of novel oral anticoagulants in UK patients with non-valvular atrial fibrillation and chronic kidney disease: a matched cohort study, BMJ Open, vol. 8, p. e019638, 2018.
J. L. Hong, Webster-Clark, M., Funk, M. J., Sturmer, T., Dempster, S., Cole, S. R., Herr, I., and LoCasale, R., Comparison of Methods to Generalize Randomized Clinical Trial Results without Individual-Level Data for the Target Population, Am J Epidemiol, 2018.
J. G. Royle, Lanyon, P. C., Grainge, M. J., Abhishek, A., and Pearce, F. A., Correction to: The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink, Clin Rheumatol, vol. 37, p. 2601, 2018.
G. Moncrieff, Lied-Lied, A., Nelson, G., Holy, C. E., Weinstein, R., Wei, D., and Rowe, S., Cost and effectiveness of prescribing emollient therapy for atopic eczema in UK primary care in children and adults: a large retrospective analysis of the Clinical Practice Research Datalink, BMC Dermatol, vol. 18, p. 9, 2018.
S. Landis, Suruki, R., Maskell, J., Bonar, K., Hilton, E., and Compton, C., Demographic and Clinical Characteristics of COPD Patients at Different Blood Eosinophil Levels in the UK Clinical Practice Research Datalink, Copd, vol. 15, pp. 177-184, 2018.
A. Leite, Thomas, S. L., and Andrews, N. J., Do delays in data availability limit the implementation of near real-time vaccine safety surveillance using the Clinical Practice Research Datalink?, Pharmacoepidemiol Drug Saf, vol. 27, pp. 25-29, 2018.
D. J. Humes, Abdul-Sultan, A., Walker, A. J., Ludvigsson, J. F., and West, J., Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study, Hernia, vol. 22, pp. 447-453, 2018.
M. Liang, Ye, T., and Fu, H., Estimating individualized optimal combination therapies through outcome weighted deep learning algorithms, Stat Med, vol. 37, pp. 3869-3886, 2018.
R. M. Joseph, van Staa, T. P., Lunt, M., Abrahamowicz, M., and Dixon, W. G., Exposure measurement error when assessing current glucocorticoid use using UK primary care electronic prescription data, Pharmacoepidemiol Drug Saf, 2018.
J. Jackson, Lewis, N. V., Feder, G. S., Whiting, P., Jones, T., Macleod, J., and Redaniel, M. T., Exposure to domestic violence and abuse and consultations for emergency contraception: nested case-control study in a UK primary care dataset, Br J Gen Pract, 2018.
J. L. Hong, M. Funk, J., LoCasale, R., Dempster, S. E., Cole, S. R., Webster-Clark, M., Edwards, J. K., and Sturmer, T., Generalizing Randomized Clinical Trial Results: Implementation and Challenges Related to Missing Data in the Target Population, Am J Epidemiol, vol. 187, pp. 817-827, 2018.
S. Vanni, Zattoni, M., Moda, F., Giaccone, G., Tagliavini, F., Haik, S., Deslys, J. P., Zanusso, G., Ironside, J. W., Carmona, M., Ferrer, I., Kovacs, G. G., and Legname, G., Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases, Front Neurosci, vol. 12, p. 8, 2018.
M. Hickman, Steer, C., Tilling, K., Lim, A. G., Marsden, J., Millar, T., Strang, J., Telfer, M., Vickerman, P., and Macleod, J., The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom, Addiction, vol. 113, pp. 1461-1476, 2018.
E. Martin-Merino, Calderon-Larranaga, A., Hawley, S., Poblador-Plou, B., Llorente-Garcia, A., Petersen, I., and Prieto-Alhambra, D., The impact of different strategies to handle missing data on both precision and bias in a drug safety study: a multidatabase multinational population-based cohort study, Clin Epidemiol, vol. 10, pp. 643-654, 2018.
J. Daugherty, Lin, X., Baxter, R., Suruki, R., and Bradford, E., The impact of long-term systemic glucocorticoid use in severe asthma: A UK retrospective cohort analysis, J Asthma, vol. 55, pp. 651-658, 2018.
K. C. Chang, Vamos, E. P., Palladino, R., Majeed, A., Lee, J. T., and Millett, C., Impact of the NHS Health Check on inequalities in cardiovascular disease risk: a difference-in-differences matching analysis, J Epidemiol Community Health, 2018.
J. G. Royle, Lanyon, P. C., Grainge, M. J., Abhishek, A., and Pearce, F. A., The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink, Clin Rheumatol, vol. 37, pp. 2103-2111, 2018.
M. Simeonova, de Vries, F., Pouwels, S., Driessen, J. H. M., Leufkens, H. G. M., Cadarette, S. M., and Burden, A. M., Increased risk of all-cause mortality associated with domperidone use in Parkinson's patients: a population-based cohort study in the UK, Br J Clin Pharmacol, vol. 84, pp. 2551-2561, 2018.
E. Richardson, Bedson, J., Chen, Y., Lacey, R., and Dunn, K. M., Increased risk of reproductive dysfunction in women prescribed long-term opioids for musculoskeletal pain: A matched cohort study in the Clinical Practice Research Datalink, Eur J Pain, vol. 22, pp. 1701-1708, 2018.
A. Jain, van Hoek, A. J., Walker, J. L., Forbes, H. J., Langan, S. M., Root, A., Smeeth, L., and Thomas, S. L., Inequalities in zoster disease burden: a population-based cohort study to identify social determinants using linked data from the U.K. Clinical Practice Research Datalink, Br J Dermatol, vol. 178, pp. 1324-1330, 2018.
S. R. Markar, Arhi, C., Leusink, A., Vidal-Diez, A., Karthikesalingam, A., Darzi, A., Lagergren, J., and Hanna, G. B., The Influence of Antireflux Surgery on Esophageal Cancer Risk in England: National Population-based Cohort Study, Ann Surg, vol. 268, pp. 861-867, 2018.
S. R. Markar, Arhi, C., Leusink, A., Vidal-Diez, A., Karthikesalingam, A., Darzi, A., Lagergren, J., and Hanna, G. B., The Influence of Antireflux Surgery on Esophageal Cancer Risk in England: National Population-based Cohort Study, Ann Surg, vol. 268, pp. 861-867, 2018.
A. D. Mosholder, Lee, J. Y., Zhou, E. H., Kang, E. M., Ghosh, M., Izem, R., Major, J. M., and Graham, D. J., Long-Term Risk of Acute Myocardial Infarction, Stroke, and Death With Outpatient Use of Clarithromycin: A Retrospective Cohort Study, Am J Epidemiol, vol. 187, pp. 786-792, 2018.
S. A. J. Schmidt, Langan, S. M., Pedersen, H. S., Schonheyder, H. C., Thomas, S. L., Smeeth, L., Mansfield, K. E., Sorensen, H. T., Forbes, H. J., and Vestergaard, M., Mood Disorders and Risk of Herpes Zoster in 2 Population-Based Case-Control Studies in Denmark and the United Kingdom, Am J Epidemiol, vol. 187, pp. 1019-1028, 2018.
L. Li, Neogi, T., and Jick, S., Mortality in Patients With Giant Cell Arteritis: A Cohort Study in UK Primary Care, Arthritis Care Res (Hoboken), vol. 70, pp. 1251-1256, 2018.
F. A. Pearce, Lanyon, P. C., Watts, R. A., Grainge, M. J., Abhishek, A., and Hubbard, R. B., Novel insights into the aetiology of granulomatosis with polyangiitis-a case-control study using the Clinical Practice Research Datalink, Rheumatology (Oxford), vol. 57, pp. 1002-1010, 2018.
C. W. le Roux, Chubb, B., Nortoft, E., and Borglykke, A., Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD), Obes Sci Pract, vol. 4, pp. 409-416, 2018.
H. J. I. De Jong, Tervaert, J. W. Cohen, Lalmohamed, A., de Vries, F., Vandebriel, R. J., Van Loveren, H., Klungel, O. H., and van Staa, T. P., Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink, PLoS One, vol. 13, p. e0193297, 2018.
A. V. Margulis, Linder, M., Arana, A., Pottegard, A., Berglind, I. A., Bui, C. L., Kristiansen, N. S., Bahmanyar, S., McQuay, L. J., Atsma, W. J., Appenteng, K., D'Silva, M., Perez-Gutthann, S., and Hallas, J., Patterns of use of antimuscarinic drugs to treat overactive bladder in Denmark, Sweden, and the United Kingdom, PLoS One, vol. 13, p. e0204456, 2018.
H. Strongman, Christopher, S., Majak, M., Williams, R., Bahmanyar, S., Linder, M., Heintjes, E. M., Bennett, D., Korhonen, P., and Hoti, F., Pioglitazone and cause-specific risk of mortality in patients with type 2 diabetes: extended analysis from a European multidatabase cohort study, BMJ Open Diabetes Res Care, vol. 6, p. e000481, 2018.
J. Busby, Mills, K., Zhang, S. D., Liberante, F. G., and Cardwell, C. R., Postdiagnostic Calcium Channel Blocker Use and Breast Cancer Mortality: A Population-based Cohort Study, Epidemiology, vol. 29, pp. 407-413, 2018.
[Page last reviewed 4 October 2019]