Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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Author Title Type [ Year(Desc)]
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2014
R. Mathur, Bhaskaran, K., Chaturvedi, N., Leon, D. A., vanStaa, T., Grundy, E., and Smeeth, L., Completeness and usability of ethnicity data in UK-based primary care and hospital databases, J Public Health (Oxf), vol. 36, pp. 684-92, 2014.
K. Wing, Douglas, I., Bhaskaran, K., Klungel, O. H., Reynolds, R. F., Pirmohamed, M., Smeeth, L., and van Staa, T. P., Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records, Drug Discov Today, vol. 19, pp. 361-6, 2014.
T. P. van Staa, Dyson, L., McCann, G., Padmanabhan, S., Belatri, R., Goldacre, B., Cassell, J., Pirmohamed, M., Torgerson, D., Ronaldson, S., Adamson, J., Taweel, A., Delaney, B., Mahmood, S., Baracaia, S., Round, T., Fox, R., Hunter, T., Gulliford, M., and Smeeth, L., The opportunities and challenges of pragmatic point-of-care randomised trials using routinely collected electronic records: evaluations of two exemplar trials, Health Technol Assess, vol. 18, pp. 1-146, 2014.
T. P. van Staa, Gulliford, M., Ng, E. S., Goldacre, B., and Smeeth, L., Prediction of cardiovascular risk using Framingham, ASSIGN and QRISK2: how well do they predict individual rather than population risk?, PLoS One, vol. 9, p. e106455, 2014.
H. J. Forbes, Bhaskaran, K., Thomas, S. L., Smeeth, L., Clayton, T., and Langan, S. M., Quantification of risk factors for herpes zoster: population based case-control study, Bmj, vol. 348, p. g2911, 2014.
S. M. Langan, Minassian, C., Smeeth, L., and Thomas, S. L., Risk of stroke following herpes zoster: a self-controlled case-series study, Clin Infect Dis, vol. 58, pp. 1497-503, 2014.
A. F. Macedo, Douglas, I., Smeeth, L., Forbes, H., and Ebrahim, S., Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink, BMC Cardiovasc Disord, vol. 14, p. 85, 2014.
J. K. Quint, Mullerova, H., DiSantostefano, R. L., Forbes, H., Eaton, S., Hurst, J. R., Davis, K., and Smeeth, L., Validation of chronic obstructive pulmonary disease recording in the Clinical Practice Research Datalink (CPRD-GOLD), BMJ Open, vol. 4, p. e005540, 2014.
2015
M. F. Barakat, McDonald, H. I., Collier, T. J., Smeeth, L., Nitsch, D., and Quint, J. K., Acute kidney injury in stable COPD and at exacerbation, Int J Chron Obstruct Pulmon Dis, vol. 10, pp. 2067-77, 2015.
K. L. Goh, Bhaskaran, K., Minassian, C., Evans, S. J., Smeeth, L., and Douglas, I. J., Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink, Br J Clin Pharmacol, vol. 79, pp. 337-50, 2015.
R. Brauer, Smeeth, L., Anaya-Izquierdo, K., Timmis, A., Denaxas, S. C., Farrington, C. P., Whitaker, H., Hemingway, H., and Douglas, I., Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study, Eur Heart J, vol. 36, pp. 984-92, 2015.
I. J. Douglas, Bhaskaran, K., Batterham, R. L., and Smeeth, L., Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care, PLoS Med, vol. 12, p. e1001925, 2015.
K. J. Rothnie, Smeeth, L., Herrett, E., Pearce, N., Hemingway, H., Wedzicha, J., Timmis, A., and Quint, J. K., Closing the mortality gap after a myocardial infarction in people with and without chronic obstructive pulmonary disease, Heart, vol. 101, pp. 1103-10, 2015.
E. Herrett, Gallagher, A. M., Bhaskaran, K., Forbes, H., Mathur, R., Van Staa, T., and Smeeth, L., Data Resource Profile: Clinical Practice Research Datalink (CPRD), Int J Epidemiol, vol. 44, pp. 827-36, 2015.
J. F. Hayes, Bhaskaran, K., Batterham, R., Smeeth, L., and Douglas, I., The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom, Int J Obes (Lond), vol. 39, pp. 1359-64, 2015.
I. J. Douglas, Bhaskaran, K., Batterham, R. L., and Smeeth, L., The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort, Br J Clin Pharmacol, vol. 79, pp. 1020-7, 2015.
R. Brauer, Bhaskaran, K., Chaturvedi, N., Dexter, D. T., Smeeth, L., and Douglas, I., Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study, PLoS Med, vol. 12, p. e1001854, 2015.
E. R. Millett, De Stavola, B. L., Quint, J. K., Smeeth, L., and Thomas, S. L., Risk factors for hospital admission in the 28 days following a community-acquired pneumonia diagnosis in older adults, and their contribution to increasing hospitalisation rates over time: a cohort study, BMJ Open, vol. 5, p. e008737, 2015.
2016
M. Pujades-Rodriguez, Duyx, B., Thomas, S. L., Stogiannis, D., Smeeth, L., and Hemingway, H., Associations between polymyalgia rheumatica and giant cell arteritis and 12 cardiovascular diseases, Heart, vol. 102, pp. 383-9, 2016.
J. K. Quint, Millett, E. R., Joshi, M., Navaratnam, V., Thomas, S. L., Hurst, J. R., Smeeth, L., and Brown, J. S., Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study, Eur Respir J, vol. 47, pp. 186-93, 2016.
A. D. Morgan, Herrett, E., De Stavola, B. L., Smeeth, L., and Quint, J. K., COPD disease severity and the risk of venous thromboembolic events: a matched case-control study, Int J Chron Obstruct Pulmon Dis, vol. 11, pp. 899-908, 2016.
A. A. Root, Wong, A. Y., Ghebremichael-Weldeselassie, Y., Smeeth, L., Bhaskaran, K., Evans, S. J., Brauer, R., Wong, I. C., Navaratnam, V., and Douglas, I., Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs, Br J Clin Pharmacol, vol. 82, pp. 512-21, 2016.
A. Matthews, Herrett, E., Gasparrini, A., Van Staa, T., Goldacre, B., Smeeth, L., and Bhaskaran, K., Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data, Bmj, vol. 353, p. i3283, 2016.
E. R. Millett, Quint, J. K., De Stavola, B. L., Smeeth, L., and Thomas, S. L., Improved incidence estimates from linked vs. stand-alone electronic health records, J Clin Epidemiol, vol. 75, pp. 66-9, 2016.
N. S. Wexler, Collett, L., Wexler, A. R., Rawlins, M. D., Tabrizi, S. J., Douglas, I., Smeeth, L., and Evans, S. J., Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review, BMJ Open, vol. 6, p. e009070, 2016.
R. Beau-Lejdstrom, Douglas, I., Evans, S. J., and Smeeth, L., Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence, BMJ Open, vol. 6, p. e010508, 2016.
E. Moore, Chatzidiakou, L., Jones, R. L., Smeeth, L., Beevers, S., Kelly, F. J., K. J, Q., and Barratt, B., Linking e-health records, patient-reported symptoms and environmental exposure data to characterise and model COPD exacerbations: protocol for the COPE study, BMJ Open, vol. 6, p. e011330, 2016.
C. Windsor, Herrett, E., Smeeth, L., and Quint, J. K., No association between exacerbation frequency and stroke in patients with COPD, Int J Chron Obstruct Pulmon Dis, vol. 11, pp. 217-25, 2016.
K. Wing, Bhaskaran, K., Smeeth, L., van Staa, T. P., Klungel, O. H., Reynolds, R. F., and Douglas, I., Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury, BMJ Open, vol. 6, p. e012102, 2016.
A. Matthews, Langan, S. M., Douglas, I. J., Smeeth, L., and Bhaskaran, K., Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink, PLoS Med, vol. 13, p. e1002037, 2016.
K. E. Mansfield, Nitsch, D., Smeeth, L., Bhaskaran, K., and Tomlinson, L. A., Prescription of renin-angiotensin system blockers and risk of acute kidney injury: a population-based cohort study, BMJ Open, vol. 6, p. e012690, 2016.
H. J. Forbes, Bhaskaran, K., Thomas, S. L., Smeeth, L., Clayton, T., Mansfield, K., Minassian, C., and Langan, S. M., Quantification of risk factors for postherpetic neuralgia in herpes zoster patients: A cohort study, Neurology, vol. 87, pp. 94-102, 2016.
K. J. Rothnie, Mullerova, H., Thomas, S. L., Chandan, J. S., Smeeth, L., Hurst, J. R., Davis, K., and Quint, J. K., Recording of hospitalizations for acute exacerbations of COPD in UK electronic health care records, Clin Epidemiol, vol. 8, pp. 771-782, 2016.
M. Pujades-Rodriguez, Duyx, B., Thomas, S. L., Stogiannis, D., Rahman, A., Smeeth, L., and Hemingway, H., Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A Population Record-Linkage Cohort Study in England, PLoS One, vol. 11, p. e0151245, 2016.
R. Brauer, Ruigomez, A., Klungel, O., Reynolds, R., M. Tepie, F., Smeeth, L., and Douglas, I., The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies, Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 39-46, 2016.
E. Herrett, Williamson, E., Van Staa, T., Ranopa, M., Free, C., Chadborn, T., Goldacre, B., and Smeeth, L., Text messaging reminders for influenza vaccine in primary care: a cluster randomised controlled trial (TXT4FLUJAB), BMJ Open, vol. 6, p. e010069, 2016.
K. J. Rothnie, Mullerova, H., Hurst, J. R., Smeeth, L., Davis, K., Thomas, S. L., and Quint, J. K., Validation of the Recording of Acute Exacerbations of COPD in UK Primary Care Electronic Healthcare Records, PLoS One, vol. 11, p. e0151357, 2016.
2017
M. Schmidt, Mansfield, K. E., Bhaskaran, K., Nitsch, D., Sorensen, H. T., Smeeth, L., and Tomlinson, L. A., Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin-angiotensin system blockade: a UK general practice-based cohort study, BMJ Open, vol. 7, p. e012818, 2017.
S. J. Sinnott, Mansfield, K. E., Schmidt, M., Bhaskaran, K., Smeeth, L., Nitsch, D., and Tomlinson, L. A., Biochemical monitoring after initiation of aldosterone antagonist therapy in users of renin-angiotensin system blockers: a UK primary care cohort study, BMJ Open, vol. 7, p. e018153, 2017.
V. Navaratnam, Millett, E. R., Hurst, J. R., Thomas, S. L., Smeeth, L., Hubbard, R. B., Brown, J., and Quint, J. K., Bronchiectasis and the risk of cardiovascular disease: a population-based study, Thorax, vol. 72, pp. 161-166, 2017.
J. P. H. Wilding, Godec, T., Khunti, K., Pocock, S., Fox, R., Smeeth, L., Clauson, P., Fenici, P., Hammar, N., and Medina, J., Changes in HbA1c and weight after initiation of second-line therapy in patients with type 2 diabetes in clinical practice., Diabetologia., vol. 60, p. S301, 2017.
E. Hansson, Forbes, H. J., Langan, S. M., Smeeth, L., and Bhaskaran, K., Herpes zoster risk after 21 specific cancers: population-based case-control study, Br J Cancer, vol. 116, pp. 1643-1651, 2017.
A. Jain, van Hoek, A. J., Walker, J. L., Mathur, R., Smeeth, L., and Thomas, S. L., Identifying social factors amongst older individuals in linked electronic health records: An assessment in a population based study, PLoS One, vol. 12, p. e0189038, 2017.
T. A. Yates, Tomlinson, L. A., Bhaskaran, K., Langan, S., Thomas, S., Smeeth, L., and Douglas, I. J., Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort, PLoS Med, vol. 14, p. e1002457, 2017.
S. A. Schmidt, Vestergaard, M., Pedersen, H. S., Schonheyder, H. C., Thomas, S. L., Smeeth, L., Mansfield, K. E., Sorensen, H. T., Forbes, H. J., and Langan, S. M., Partner Bereavement and Risk of Herpes Zoster: Results from Two Population-Based Case-Control Studies in Denmark and the United Kingdom, Clin Infect Dis, vol. 64, pp. 572-579, 2017.
R. Mathur, Bhaskaran, K., Edwards, E., Lee, H., Chaturvedi, N., Smeeth, L., and Douglas, I., Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014, BMJ Open, vol. 7, p. e014444, 2017.
M. Iwagami, Tomlinson, L. A., Mansfield, K. E., McDonald, H. I., Smeeth, L., and Nitsch, D., Prevalence, incidence, indication, and choice of antidepressants in patients with and without chronic kidney disease: a matched cohort study in UK Clinical Practice Research Datalink, Pharmacoepidemiol Drug Saf, vol. 26, pp. 792-801, 2017.
K. Wing, Bhaskaran, K., Pealing, L., Root, A., Smeeth, L., van Staa, T. P., Klungel, O. H., Reynolds, R. F., and Douglas, I., Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study, J Antimicrob Chemother, vol. 72, pp. 2636-2646, 2017.
M. Schmidt, Mansfield, K. E., Bhaskaran, K., Nitsch, D., Sorensen, H. T., Smeeth, L., and Tomlinson, L. A., Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study, Bmj, vol. 356, p. j791, 2017.
S. J. Sinnott, Smeeth, L., Williamson, E., and Douglas, I. J., Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015, Bmj, vol. 358, p. j3984, 2017.
[Page last reviewed 4 November 2019]