Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 7 September 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 209 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2588 results:
Author [ Title(Desc)] Type Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
Y. Lis, Spitzer, W. O., Mann, R. D., Chukwujindu, J., Thorogood, M., Evans, S., Suissa, S., and Lelorier, J., A concurrent cohort study of oral contraceptive users from the VAMP research bank, Pharmacoepidemiology and Drug Safety, vol. 2, pp. 51-63, 1993.
D. J. Humes, Fleming, K. M., Spiller, R. C., and West, J., Concurrent drug use and the risk of perforated colonic diverticular disease: a population-based case-control study, Gut, vol. 60, pp. 219-24, 2011.
L. Azoulay, Dell'Aniello, S., Simon, T., Renoux, C., and Suissa, S., The concurrent use of antithrombotic therapies and the risk of bleeding in patients with atrial fibrillation, Thromb Haemost, vol. 109, pp. 431-9, 2013.
F. Lapi, Azoulay, L., Yin, H., Nessim, S. J., and Suissa, S., Concurrent use of diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers with non-steroidal anti-inflammatory drugs and risk of acute kidney injury: nested case-control study, Bmj, vol. 346, p. e8525, 2013.
S. Suissa, Dell'Aniello, S., and Ernst, P., Concurrent use of long-acting bronchodilators in COPD and the risk of adverse cardiovascular events, Eur Respir J, vol. 49, 2017.
J. P. Fournier, Duijnhoven, R. G., Renoux, C., Dell'Aniello, S., Klungel, O. H., and Suissa, S., Concurrent use of statins and hormone therapy and risk of venous thromboembolism in postmenopausal women: a population-based case-control study, Menopause, vol. 21, pp. 1023-6, 2014.
L. Azoulay, Dell'Aniello, S., Huiart, L., Fort, G. G. du, and Suissa, S., Concurrent use of tamoxifen with CYP2D6 inhibitors and the risk of breast cancer recurrence, Breast Cancer Res Treat, vol. 126, pp. 695-703, 2011.
L. Watson, Das, R., Farquhar, R., Langerman, H., and Barnett, A. H., Consequences of delaying treatment intensification in type 2 diabetes: evidence from a UK database, Curr Med Res Opin, vol. 32, pp. 1465-75, 2016.
S. Rowlands and Moser, K., Consultation rates from the general practice research database, Br J Gen Pract, vol. 52, pp. 658-60, 2002.
M. J. van Bommel, Numans, M. E., de Wit, N. J., and Stalman, W. A., Consultations and referrals for dyspepsia in general practice–a one year database survey, Postgrad Med J, vol. 77, pp. 514-8, 2001.
I. Williamson, Benge, S., Mullee, M., and Little, P., Consultations for middle ear disease, antibiotic prescribing and risk factors for reattendance: a case-linked cohort study, Br J Gen Pract, vol. 56, pp. 170-5, 2006.
N. F. Khan, Ward, A. M., Watson, E., and Rose, P. W., Consulting and prescribing behaviour for anxiety and depression in long-term survivors of cancer in the UK, Eur J Cancer, vol. 46, pp. 3339-44, 2010.
D. A. Rees, Jenkins-Jones, S., and Morgan, C. L., Contemporary Reproductive Outcomes for Patients With Polycystic Ovary Syndrome: A Retrospective Observational Study, J Clin Endocrinol Metab, vol. 101, pp. 1664-72, 2016.
M. Olsson, Schnecke, V., Cabrera, C., Skrtic, S., and Lind, M., Contemporary Risk Estimates of Three HbA1c Variables for Myocardial Infarction in 101,799 Patients Following Diagnosis of Type 2 Diabetes, Diabetes Care, vol. 38, pp. 1481-6, 2015.
S. Skrtic, Cabrera, C., Olsson, M., Schnecke, V., and Lind, M., Contemporary risk estimates of three HbA1c variables in relation to heart failure following diagnosis of type 2 diabetes, Heart, vol. 103, pp. 353-358, 2017.
M. C. Gulliford, Dregan, A., Moore, M. V., Ashworth, M., Staa, T., McCann, G., Charlton, J., Yardley, L., Little, P., and McDermott, L., Continued high rates of antibiotic prescribing to adults with respiratory tract infection: survey of 568 UK general practices, BMJ Open, vol. 4, p. e006245, 2014.
P. Tammes, Purdy, S., Salisbury, C., MacKichan, F., Lasserson, D., and Morris, R. W., Continuity of Primary Care and Emergency Hospital Admissions Among Older Patients in England, Ann Fam Med, vol. 15, pp. 515-522, 2017.
C. Schneider, Jick, S. S., Bothner, U., and Meier, C. R., COPD and the risk of depression, Chest, vol. 137, pp. 341-7, 2010.
A. D. Morgan, Herrett, E., De Stavola, B. L., Smeeth, L., and Quint, J. K., COPD disease severity and the risk of venous thromboembolic events: a matched case-control study, Int J Chron Obstruct Pulmon Dis, vol. 11, pp. 899-908, 2016.
E. Merinopoulou, Raluy-Callado, M., Ramagopalan, S., MacLachlan, S., and Khalid, J. M., COPD exacerbations by disease severity in England, Int J Chron Obstruct Pulmon Dis, vol. 11, pp. 697-709, 2016.
Y. S. Punekar, Shukla, A., and Mullerova, H., COPD management costs according to the frequency of COPD exacerbations in UK primary care, Int J Chron Obstruct Pulmon Dis, vol. 9, pp. 65-73, 2014.
J. G. Royle, Lanyon, P. C., Grainge, M. J., Abhishek, A., and Pearce, F. A., Correction to: The incidence, prevalence, and survival of systemic sclerosis in the UK Clinical Practice Research Datalink, Clin Rheumatol, vol. 37, p. 2601, 2018.
C. Deschaseaux-Voinet, Lafuma, A., and Berdeaux, G., Cost and effectiveness of brinzolamide versus dorzolamide in current practice: an analysis based on the UK-GPRD database, J Med Econ, vol. 6, pp. 69-78, 2003.
G. Moncrieff, Lied-Lied, A., Nelson, G., Holy, C. E., Weinstein, R., Wei, D., and Rowe, S., Cost and effectiveness of prescribing emollient therapy for atopic eczema in UK primary care in children and adults: a large retrospective analysis of the Clinical Practice Research Datalink, BMC Dermatol, vol. 18, p. 9, 2018.
R. De Natale, Lafuma, A., and Berdeaux, G., Cost effectiveness of travoprost versus a fixed combination of latanoprost/timolol in patients with ocular hypertension or glaucoma: analysis based on the UK general practitioner research database, Clin Drug Investig, vol. 29, pp. 111-20, 2009.
P. Dolan and Torgerson, D. J., The cost of treating osteoporotic fractures in the United Kingdom female population, Osteoporos Int, vol. 8, pp. 611-7, 1998.
C. I. Bloom, Douglas, I., Olney, J., D'Ancona, G., Smeeth, L., and Quint, J. K., Cost saving of switching to equivalent inhalers and its effect on health outcomes, Thorax, 2019.
M. C. Gulliford, Bhattarai, N., Charlton, J., and Rudisill, C., Cost-effectiveness of a universal strategy of brief dietary intervention for primary prevention in primary care: population-based cohort study and Markov model, Cost Eff Resour Alloc, vol. 12, p. 4, 2014.
S. J. Ronaldson, Raghunath, A., Torgerson, D. J., and Van Staa, T., Cost-effectiveness of antibiotics for COPD management: observational analysis using CPRD data, ERJ Open Res, vol. 3, 2017.
R. J. Pitman, Nagy, L. D., and Sculpher, M. J., Cost-effectiveness of childhood influenza vaccination in England and Wales: Results from a dynamic transmission model, Vaccine, vol. 31, pp. 927-42, 2013.
J. Leal, Gray, A. M., Hawley, S., Prieto-Alhambra, D., Delmestri, A., Arden, N. K., Cooper, C., Javaid, M. K., and Judge, A., Cost-Effectiveness of Orthogeriatric and Fracture Liaison Service Models of Care for Hip Fracture Patients: A Population-Based Study, J Bone Miner Res, vol. 32, pp. 203-211, 2017.
A. Lafuma and Berdeaux, G., Costs and effectiveness of travoprost versus a dorzolamide + timolol fixed combination in first-line treatment of glaucoma: analysis conducted on the United Kingdom General Practitioner Research Database, Curr Med Res Opin, vol. 23, pp. 3009-16, 2007.
M. C. Gulliford, Charlton, J., Prevost, T., Booth, H., Fildes, A., Ashworth, M., Littlejohns, P., Reddy, M., Khan, O., and Rudisill, C., Costs and Outcomes of Increasing Access to Bariatric Surgery: Cohort Study and Cost-Effectiveness Analysis Using Electronic Health Records, Value Health, vol. 20, pp. 85-92, 2017.
P. Denis, Lafuma, A., and Berdeaux, G., Costs and persistence of alpha-2 adrenergic agonists versus carbonic anhydrase inhibitors, both associated with prostaglandin analogues, for glaucoma as recorded by The United Kingdom General Practitioner Research Database, Clin Ophthalmol, vol. 2, pp. 321-9, 2008.
A. Lafuma, Laurendeau, C., and Berdeaux, G., Costs and persistence of brimonidine versus brinzolamide in everyday glaucoma care: an analysis conducted on the UK General Practitioner Research Database, J Med Econ, vol. 11, pp. 485-97, 2008.
A. Lafuma and Berdeaux, G., Costs and persistence of carbonic anhydrase inhibitor versus alpha-2 agonists, associated with beta-blockers, in glaucoma and ocular hypertension: an analysis of the UK-GPRD database, Curr Med Res Opin, vol. 24, pp. 1519-27, 2008.
J. Hong, Reed, C., Novick, D., and Happich, M., Costs associated with treatment of chronic low back pain: an analysis of the UK General Practice Research Database, Spine (Phila Pa 1976), vol. 38, pp. 75-82, 2013.
P. Dolan, Torgerson, D. J., and Wolstenholme, J., Costs of breast cancer treatment in the United Kingdom, Breast, vol. 8, pp. 205-7, 1999.
S. V. Ramagopalan, Samnaliev, M., Weir, S., Sammon, C. J., Carroll, R., and Alikhan, R., Costs of gastrointestinal bleeding events in atrial fibrillation: a UK Clinical Practice Research Datalink study, Future Cardiol, 2019.
E. Ford, Starlinger, J., Rooney, P., Oliver, S., Banerjee, S., van Marwijk, H., and Cassell, J., Could dementia be detected from UK primary care patients' records by simple automated methods earlier than by the treating physician? A retrospective case-control study, Wellcome Open Res, vol. 5, p. 120, 2020.
K. C. Chang, Soljak, M., Lee, J. T., Woringer, M., Johnston, D., Khunti, K., Majeed, A., and Millett, C., Coverage of a national cardiovascular risk assessment and management programme (NHS Health Check): Retrospective database study, Prev Med, vol. 78, pp. 1-8, 2015.
N. M. Davies, Smith, G. D., Windmeijer, F., and Martin, R. M., COX-2 selective nonsteroidal anti-inflammatory drugs and risk of gastrointestinal tract complications and myocardial infarction: an instrumental variable analysis, Epidemiology, vol. 24, pp. 352-62, 2013.
O. A. Oshagbemi, Franssen, F. M. E., Wouters, E. F. M., van der Zee, A. H. Maitlan, Driessen, J. H. M., de Boer, A., and de Vries, F., C-reactive protein as a biomarker of response to inhaled corticosteroids among patients with COPD, Pulm Pharmacol Ther, p. 101870, 2019.
C. Francois, Tanasescu, A., Lamy, F. X., Despiegel, N., Falissard, B., Chalem, Y., Lancon, C., Llorca, P. M., Saragoussi, D., Verpillat, P., Wade, A. G., and Zighed, D. A., Creating an index to measure health state of depressed patients in automated healthcare databases: the methodology, J Mark Access Health Policy, vol. 5, p. 1372025, 2017.
M. Touya, Lamy, F. X., Tanasescu, A., Saragoussi, D., Francois, C., Wade, A. G., Llorca, P. M., Lancon, C., and Falissard, B., Creation and validation of a linear index to measure the health state of patients with depression in automated healthcare databases, J Mark Access Health Policy, vol. 7, p. 1674115, 2019.
R. Boggon, Eaton, S., Timmis, A., Hemingway, H., Gabriel, H., Minhas, I., and van Staa, T. P., Current prescribing of statins and persistence to statins following ACS in the UK: a MINAP/GPRD study, Br J Cardiol, vol. 19, p. 24, 2012.
L. M. Fischer, Schlienger, R. G., Matter, C. M., Jick, H., and Meier, C. R., Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction, Pharmacotherapy, vol. 25, pp. 503-10, 2005.
R. G. Schlienger, Fischer, L. M., Jick, H., and Meier, C. R., Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction, Drug Saf, vol. 27, pp. 1157-65, 2004.
F. Andersohn, Schade, R., Suissa, S., and Garbe, E., Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study, Stroke, vol. 37, pp. 1725-30, 2006.
A. W. Lim, Landy, R., Castanon, A., Hollingworth, A., Hamilton, W., Dudding, N., and Sasieni, P., Cytology in the diagnosis of cervical cancer in symptomatic young women: a retrospective review, Br J Gen Pract, vol. 66, pp. e871-e879, 2016.
[Page last reviewed 7 September 2020]