Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 7 September 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 209 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2588 results:
Author Title Type [ Year(Desc)]
C. Huerta, Johansson, S., Wallander, M. A., and Rodriguez, L. A. Garcia, Risk factors and short-term mortality of venous thromboembolism diagnosed in the primary care setting in the United Kingdom, Arch Intern Med, vol. 167, pp. 935-43, 2007.
F. N. Aberra, Stettler, N., Brensinger, C., Lichtenstein, G. R., and Lewis, J. D., Risk for active tuberculosis in inflammatory bowel disease patients, Clin Gastroenterol Hepatol, vol. 5, pp. 1070-5, 2007.
A. Ruigomez, Rodriguez, L. A. Garcia, Johansson, S., Wallander, M. A., and Edvardsson, N., Risk of cerebrovascular accident after a first diagnosis of atrial fibrillation, Clin Cardiol, vol. 30, pp. 624-8, 2007.
R. Srinivasan, Yang, Y. X., Rubin, S. C., Morgan, M. A., and Lewis, J. D., Risk of colorectal cancer in women with a prior diagnosis of gynecologic malignancy, J Clin Gastroenterol, vol. 41, pp. 291-6, 2007.
A. L. Smitten, Choi, H. K., Hochberg, M. C., Suissa, S., Simon, T. A., Testa, M. A., and Chan, K. A., The risk of herpes zoster in patients with rheumatoid arthritis in the United States and the United Kingdom, Arthritis Rheum, vol. 57, pp. 1431-8, 2007.
L. Howard, Kirkwood, G., and Leese, M., Risk of hip fracture in patients with a history of schizophrenia, Br J Psychiatry, vol. 190, pp. 129-34, 2007.
J. M. Gelfand, Troxel, A. B., Lewis, J. D., Kurd, S. K., Shin, D. B., Wang, X., Margolis, D. J., and Strom, B. L., The risk of mortality in patients with psoriasis: results from a population-based study, Arch Dermatol, vol. 143, pp. 1493-9, 2007.
A. Rubino, Roskell, N., Tennis, P., Mines, D., Weich, S., and Andrews, E., Risk of suicide during treatment with venlafaxine, citalopram, fluoxetine, and dothiepin: retrospective cohort study, Bmj, vol. 334, p. 242, 2007.
R. L. Tannen, Weiner, M. G., Xie, D., and Barnhart, K., A simulation using data from a primary care practice database closely replicated the women's health initiative trial, J Clin Epidemiol, vol. 60, pp. 686-95, 2007.
R. G. Schlienger, Fedson, D. S., Jick, S. S., Jick, H., and Meier, C. R., Statins and the risk of pneumonia: a population-based, nested case-control study, Pharmacotherapy, vol. 27, pp. 325-32, 2007.
A. L. Nightingale, Farmer, R. D., and de Vries, C. S., Systemic lupus erythematosus prevalence in the UK: methodological issues when using the General Practice Research Database to estimate frequency of chronic relapsing-remitting disease, Pharmacoepidemiol Drug Saf, vol. 16, pp. 144-51, 2007.
M. A. Wallander, Johansson, S., Ruigomez, A., and Rodriguez, L. A. Garcia, Unspecified abdominal pain in primary care: the role of gastrointestinal morbidity, Int J Clin Pract, vol. 61, pp. 1663-70, 2007.
W. P. Bowe, Hoffstad, O., and Margolis, D. J., Upper respiratory tract infection in household contacts of acne patients, Dermatology, vol. 215, pp. 213-8, 2007.
G. Hughes, Williams, T., Simms, I., Mercer, C., Fenton, K., and Cassell, J., Use of a primary care database to determine trends in genital chlamydia testing, diagnostic episodes and management in UK general practice, 1990-2004, Sex Transm Infect, vol. 83, pp. 310-3, 2007.
M. Sharland, The use of antibacterials in children: a report of the Specialist Advisory Committee on Antimicrobial Resistance (SACAR) Paediatric Subgroup, J Antimicrob Chemother, vol. 60 Suppl 1, pp. i15-26, 2007.
N. Dunn, Lane, D., Everitt, H., and Little, P., Use of antibiotics for sore throat and incidence of quinsy, Br J Gen Pract, vol. 57, pp. 45-9, 2007.
F. de Vries, Souverein, P. C., Cooper, C., Leufkens, H. G., and van Staa, T. P., Use of beta-blockers and the risk of hip/femur fracture in the United Kingdom and The Netherlands, Calcif Tissue Int, vol. 80, pp. 69-75, 2007.
K. E. Wurst, Ephross, S. A., Loehr, J., Clark, D. W., and Guess, H. A., The utility of the general practice research database to examine selected congenital heart defects: a validation study, Pharmacoepidemiol Drug Saf, vol. 16, pp. 867-77, 2007.
S. A. Bremner, Carey, I. M., DeWilde, S., Richards, N., Maier, W. C., Hilton, S. R., Strachan, D. P., and Cook, D. G., Vaccinations, infections and antibacterials in the first grass pollen season of life and risk of later hayfever, Clin Exp Allergy, vol. 37, pp. 512-7, 2007.
H. E. Seaman, Langley, S. E., Farmer, R. D., and de Vries, C. S., Venous thromboembolism and cyproterone acetate in men with prostate cancer: a study using the General Practice Research Database, BJU Int, vol. 99, pp. 1398-403, 2007.
S. B. Meropol, Chan, K. A., Chen, Z., Finkelstein, J. A., Hennessy, S., Lautenbach, E., Platt, R., Schech, S. D., Shatin, D., and Metlay, J. P., Adverse events associated with prolonged antibiotic use, Pharmacoepidemiol Drug Saf, vol. 17, pp. 523-32, 2008.
D. Nitsch, Douglas, I., Smeeth, L., and Fletcher, A., Age-related macular degeneration and complement activation-related diseases: a population-based case-control study, Ophthalmology, vol. 115, pp. 1904-10, 2008.
S. S. Jick and Li, L., Antidepressant drug use and risk of venous thromboembolism, Pharmacotherapy, vol. 28, pp. 144-50, 2008.
Y. B. Brauchli, Jick, S. S., Curtin, F., and Meier, C. R., Association between beta-blockers, other antihypertensive drugs and psoriasis: population-based case-control study, Br J Dermatol, vol. 158, pp. 1299-307, 2008.
Y. B. Brauchli, Jick, S. S., Curtin, F., and Meier, C. R., Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: A population based case-control study, J Am Acad Dermatol, vol. 58, pp. 421-9, 2008.
E. Setakis, Leufkens, H. G., and van Staa, T. P., Changes in the characteristics of patients prescribed selective cyclooxygenase 2 inhibitors after the 2004 withdrawal of rofecoxib, Arthritis Rheum, vol. 59, pp. 1105-11, 2008.
S. Rietbrock, Heeley, E., Plumb, J., and Van Staa, T., Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification scheme, Am Heart J, vol. 156, pp. 57-64, 2008.
Y. X. Yang, Hennessy, S., Propert, K., Hwang, W. T., Sarkar, M., and Lewis, J. D., Chronic statin therapy and the risk of colorectal cancer, Pharmacoepidemiol Drug Saf, vol. 17, pp. 869-76, 2008.
J. Griffin, Lee, S., Caiado, M., Kesten, S., and Price, D., Comparison of tiotropium bromide and combined ipratropium/salbutamol for the treatment of COPD: a UK General Practice Research Database 12-month follow-up study, Prim Care Respir J, vol. 17, pp. 104-10, 2008.
P. Denis, Lafuma, A., and Berdeaux, G., Costs and persistence of alpha-2 adrenergic agonists versus carbonic anhydrase inhibitors, both associated with prostaglandin analogues, for glaucoma as recorded by The United Kingdom General Practitioner Research Database, Clin Ophthalmol, vol. 2, pp. 321-9, 2008.
A. Lafuma, Laurendeau, C., and Berdeaux, G., Costs and persistence of brimonidine versus brinzolamide in everyday glaucoma care: an analysis conducted on the UK General Practitioner Research Database, J Med Econ, vol. 11, pp. 485-97, 2008.
A. Lafuma and Berdeaux, G., Costs and persistence of carbonic anhydrase inhibitor versus alpha-2 agonists, associated with beta-blockers, in glaucoma and ocular hypertension: an analysis of the UK-GPRD database, Curr Med Res Opin, vol. 24, pp. 1519-27, 2008.
R. A. Charlton, Cunnington, M. C., de Vries, C. S., and Weil, J. G., Data resources for investigating drug exposure during pregnancy and associated outcomes: the General Practice Research Database (GPRD) as an alternative to pregnancy registries, Drug Saf, vol. 31, pp. 39-51, 2008.
T. A. Hammad, McAdams, M. A., Feight, A., Iyasu, S., and Dal Pan, G. J., Determining the predictive value of Read/OXMIS codes to identify incident acute myocardial infarction in the General Practice Research Database, Pharmacoepidemiol Drug Saf, vol. 17, pp. 1197-201, 2008.
C. Becker, Brobert, G. P., Johansson, S., Jick, S. S., and Meier, C. R., Diabetes in patients with idiopathic Parkinson's disease, Diabetes Care, vol. 31, pp. 1808-12, 2008.
S. S. Daskalopoulou, Delaney, J. A., Filion, K. B., Brophy, J. M., Mayo, N. E., and Suissa, S., Discontinuation of statin therapy following an acute myocardial infarction: a population-based study, Eur Heart J, vol. 29, pp. 2083-91, 2008.
T. P. van Staa, Rietbrock, S., Setakis, E., and Leufkens, H. G., Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?, J Intern Med, vol. 264, pp. 481-92, 2008.
H. E. Seaman, Ballard, K. D., Wright, J. T., and de Vries, C. S., Endometriosis and its coexistence with irritable bowel syndrome and pelvic inflammatory disease: findings from a national case-control study–Part 2, Bjog, vol. 115, pp. 1392-6, 2008.
F. Rani, Murray, M. L., Byrne, P. J., and Wong, I. C., Epidemiologic features of antipsychotic prescribing to children and adolescents in primary care in the United Kingdom, Pediatrics, vol. 121, pp. 1002-9, 2008.
T. P. van Staa, Smeeth, L., Persson, I., Parkinson, J., and Leufkens, H. G., Evaluating drug toxicity signals: is a hierarchical classification of evidence useful or a hindrance?, Pharmacoepidemiol Drug Saf, vol. 17, pp. 475-84, 2008.
J. Charlton, Latinovic, R., and Gulliford, M. C., Explaining the decline in early mortality in men and women with type 2 diabetes: a population-based cohort study, Diabetes Care, vol. 31, pp. 1761-6, 2008.
I. J. Douglas and Smeeth, L., Exposure to antipsychotics and risk of stroke: self controlled case series study, Bmj, vol. 337, p. a1227, 2008.
A. M. Gallagher, Rietbrock, S., Olson, M., and van Staa, T. P., Fracture outcomes related to persistence and compliance with oral bisphosphonates, J Bone Miner Res, vol. 23, pp. 1569-75, 2008.
L. Opatrny, Delaney, J. A., and Suissa, S., Gastro-intestinal haemorrhage risks of selective serotonin receptor antagonist therapy: a new look, Br J Clin Pharmacol, vol. 66, pp. 76-81, 2008.
P. L. Thompson, Gilbert, R. E., Long, P. F., Saxena, S., Sharland, M., and Wong, I. C., Has UK guidance affected general practitioner antibiotic prescribing for otitis media in children?, J Public Health (Oxf), vol. 30, pp. 479-86, 2008.
C. Renoux, Dell'Aniello, S., Garbe, E., and Suissa, S., Hormone replacement therapy use and the risk of stroke, Maturitas, vol. 61, pp. 305-9, 2008.
M. G. Weiner, Barnhart, K., Xie, D., and Tannen, R. L., Hormone therapy and coronary heart disease in young women, Menopause, vol. 15, pp. 86-93, 2008.
S. L. Thomas, Edwards, C. J., Smeeth, L., Cooper, C., and Hall, A. J., How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the general practice research database?, Arthritis Rheum, vol. 59, pp. 1314-21, 2008.
J. D. Lewis, Gelfand, J. M., Troxel, A. B., Forde, K. A., Newcomb, C., Kim, H., Margolis, D. J., and Strom, B. L., Immunosuppressant medications and mortality in inflammatory bowel disease, Am J Gastroenterol, vol. 103, pp. 1428-35; quiz 1436, 2008.
T. R. Card, Solaymani-Dodaran, M., and West, J., Incidence and mortality of primary sclerosing cholangitis in the UK: a population-based cohort study, J Hepatol, vol. 48, pp. 939-44, 2008.
[Page last reviewed 7 September 2020]