Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 3,000 peer-reviewed publications. The CPRD bibliography listed below is updated on a monthly basis (last updated 4 March 2024).

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

Download: CPRD bibliography PDF March 2024 (PDF, 4.2MB, 313 pages) 

Download: CPRD bibliography .BIB March 2024 (BIB, 1.3MB, 1 page)

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website

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Year Sort ascending Title
2020

Generating high-fidelity synthetic patient data for assessing machine learning healthcare software

10.1038/s41746-020-00353-9

Authors: A Tucker, Z Wang, Y Rotalinti, P Myles

2020

Gender Differences in Inhaled Pharmacotherapy Utilization in Patients with Obstructive Airway Diseases (OADs): A Population-Based Study

10.2147/copd.s264580

Authors: J. Amegadzie, J. Gamble, J. Farrell, Z. Gao

2020

Fertility trends of women with serious mental illness in the United Kingdom 1992-2017: A primary care cohort study using the clinical practice research datalink

10.1016/j.jad.2020.03.037

Authors: H. Hope, R. Parisi, D. Ashcroft, R. Williams, S. Coton, K. Kosidou, M. Pierce, K. Abel

2020

Feasibility of using Clinical Practice Research Datalink data to identify patients with chronic obstructive pulmonary disease to enrol into real-world trials

10.1002/pds.5188

Authors: G. Requena, A. Wolf, R. Williams, D. Dedman, J. Quint, T. Murray-Thomas, J. Pimenta

2020

Factors associated with non-prescription of oral anticoagulant treatment in non-valvular atrial fibrillation patients with dementia: a CPRD-HES study

10.1093/ageing/afaa045

Authors: M. Besford, S. Graham, C. Sammon, F. Mehmud, V. Allan, R. Alikhan, S. Ramagopalan

2020

Examining the impact of data quality and completeness of electronic health records on predictions of patients\textquoteright risks of cardiovascular disease

10.1016/j.ijmedinf.2019.104033

Authors: Y. Li, M. Sperrin, G. Martin, D. Ashcroft, T. van Staa

2020

Evaluating the Risk of Macrovascular Events and Mortality Among People With Multiple Sclerosis in England

10.1001/jamaneurol.2020.0664

Authors: R. Palladino, R. Marrie, A. Majeed, J. Chataway

2020

Evaluating the Effectiveness of an Additional Risk Minimization Measure to Reduce the Risk of Prescribing Mirabegron to Patients with Severe Uncontrolled Hypertension in Four European Countries

10.2147/clep.s242065

Authors: E. Heintjes, I. Bezemer, D. Prieto-Alhambra, E. Smits, H. Booth, D. Dedman, Y. He, F. Hoti, M. Vehkala, S. de Vogel, N. Robinson, K. Appenteng, F. van Beest

2020

Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990-2017: A cohort study

10.1371/journal.pmed.1003106

Authors: R. Mathur, R. Farmer, S. Eastwood, N. Chaturvedi, I. Douglas, L. Smeeth

2020

Ethnic differences in the severity and clinical management of type 2 diabetes at time of diagnosis: A cohort study in the UK Clinical Practice Research Datalink

10.1016/j.diabres.2020.108006

Authors: R. Mathur, L. Palla, R. Farmer, N. Chaturvedi, L. Smeeth

2020

Estimation of the increased risk associated with recurrent events or polyvascular atherosclerotic cardiovascular disease in the United Kingdom

10.1177/2047487319899212

Authors: M. Danese, P. Pemberton-Ross, D. Catterick, G. Villa

2020

Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study

10.1016/s0140-6736(20)30854-0

Authors: A. Banerjee, L. Pasea, S. Harris, A. Gonzalez-Izquierdo, A. Torralbo, L. Shallcross, M. Noursadeghi, D. Pillay, N. Sebire, C. Holmes, C. Pagel, W. Wong, C. Langenberg, B. Williams, S. Denaxas, H. Hemingway

2020

Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study

10.1136/bmjopen-2020-043828

Authors: A. Lai, L. Pasea, A. Banerjee, G. Hall, S. Denaxas, W. Chang, M. Katsoulis, B. Williams, D. Pillay, M. Noursadeghi, D. Linch, D. Hughes, M. Forster, C. Turnbull, N. Fitzpatrick, K. Boyd, G. Foster, T. Enver, V. Nafilyan, B. Humberstone, R. Neal, M. Cooper, M. Jones, K. Pritchard-Jones, R. Sullivan, C. Davie, M. Lawler, H. Hemingway

2020

Consistency of variety of machine learning and statistical models in predicting clinical risks of individual patients: longitudinal cohort study using cardiovascular disease as exemplar

10.1136/bmj.m3919

Authors: Y. Li, M. Sperrin, D. Ashcroft, T. van Staa

2020

Epidemiology of systemic sclerosis in the UK: an analysis of the Clinical Practice Research Datalink

10.1093/rheumatology/keaa680

Authors: J. Pauling, A. McGrogan, J. Snowball, N. McHugh

2020

The Epidemiology of Malignant Melanoma, Squamous Cell Carcinoma, and Basal Cell Carcinoma in the United Kingdom from 2004-2014: A Population-Based Cohort Analysis using the Clinical Practice Research Datalink

10.1111/bjd.19542

Authors: F. Mirza, S. Yumeen, F. Walter

2020

Epidemiology and determinants of non-diabetic hyperglycaemia and its conversion to type 2 diabetes mellitus, 2000-2015: cohort population study using UK electronic health records

10.1136/bmjopen-2020-040201

Authors: R. Ravindrarajah, D. Reeves, E. Howarth, R. Meacock, C. Soiland-Reyes, S. Cotterill, W. Whittaker, S. Heller, M. Sutton, P. Bower, E. Kontopantelis

2020

Epidemiology and outcomes of gastroparesis, as documented in general practice records, in the United Kingdom

10.1136/gutjnl-2020-321277

Authors: Y. Ye, B. Jiang, S. Manne, P. Moses, C. Almansa, D. Bennett, P. Dolin, A. Ford

2020

Costs of joint replacement in osteoarthritis: a study using the National Joint Registry and Clinical Practice Research Datalink datasets

10.1002/acr.24470

Authors: J. Leal, J. Murphy, C. Garriga, A. Delmestri, A. Rangan, A. Price, A. Carr, D. Prieto-Alhambra, A. Judge

2020

Cough presentation in primary care and the identification of chronic cough: a need for diagnostic clarity?

10.1080/03007995.2019.1673716

Authors: S. Holden, A. Morice, S. Birring, S. Jenkins-Jones, H. Langerman, J. Weaver, C. Currie

2020

Could dementia be detected from UK primary care patients\textquoteright records by simple automated methods earlier than by the treating physician? A retrospective case-control study

10.12688/wellcomeopenres.15903.1

Authors: E. Ford, J. Starlinger, P. Rooney, S. Oliver, S. Banerjee, H. van Marwijk, J. Cassell

2020

CPRD Aurum database: Assessment of data quality and completeness of three important comorbidities

10.1002/pds.5135

Authors: R. Persson, C. Vasilakis-Scaramozza, K. Hagberg, T. Sponholtz, T. Williams, P. Myles, S. Jick

2020

Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015)

10.1136/bmjopen-2019-034396

Authors: P. Rockenschaub, V. Nguyen, R. Aldridge, D. Acosta, J. Garcia-Gomez, C. Saez

2020

Deep learning for electronic health records: A comparative review of multiple deep neural architectures

10.1016/j.jbi.2019.103337

Authors: J. Solares, F. Raimondi, Y. Zhu, F. Rahimian, D. Canoy, J. Tran, A. Gomes, A. Payberah, M. Zottoli, M. Nazarzadeh, N. Conrad, K. Rahimi, G. Salimi-Khorshidi

2020

Delays in referral from primary care worsen survival for patients with colorectal cancer: a retrospective cohort study

10.3399/bjgp20X710441

Authors: C. Arhi, E. Burns, A. Bottle, G. Bouras, P. Aylin, P. Ziprin, A. Darzi

2020

Depression in individuals who subsequently develop inflammatory bowel disease: a population-based nested case-control study

10.1136/gutjnl-2020-322308

Authors: J. Blackwell, S. Saxena, I. Petersen, M. Hotopf, H. Creese, A. Bottle, C. Alexakis, R. Pollok

2020

Determinants of referral of women with urinary incontinence to specialist services: a national cohort study using primary care data from the UK

10.1186/s12875-020-01282-y

Authors: I. Gurol-Urganci, R. Geary, J. Mamza, M. Iwagami, D. El-Hamamsy, J. Duckett, A. Wilson, D. Tincello, J. van der Meulen

2020

Determination of healthcare resource and cost implications of using alternative sodium valproate formulations in the treatment of epilepsy in children in England: a retrospective database review

10.1016/j.ejpb.2020.12.007

Authors: H. Batchelor

2020

Development and Validation of a Clinical Prediction Tool for Seasonal Influenza Vaccination in England

10.1001/jamanetworkopen.2020.7743

Authors: M. Loiacono, N. Mitsakakis, J. Kwong, G. Gomez, A. Chit, P. Grootendorst

2020

Development and Validation of a Method to Estimate COPD Severity in Multiple Datasets: A Retrospective Study

10.1007/s41030-020-00139-0

Authors: J. Quint, C. O\textquoterightLeary, A. Venerus, U. Holmgren, P. Varghese, C. Cabrera

2020

Development and validation of a multivariable prediction model for infection-related complications in patients with common infections in UK primary care and the extent of risk-based prescribing of antibiotics

10.1186/s12916-020-01581-2

Authors: C. Mistry, V. Palin, Y. Li, G. Martin, D. Jenkins, W. Welfare, D. Ashcroft, T. Van Staa

2020

Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study

10.1136/bmjdrc-2019-000962

Authors: S. Zghebi, M. Mamas, D. Ashcroft, C. Salisbury, C. Mallen, C. Chew-Graham, D. Reeves, H. van Marwijk, N. Qureshi, S. Weng, T. Holt, I. Buchan, N. Peek, S. Giles, M. Rutter, E. Kontopantelis

2020

Development and validation of the Cambridge Multimorbidity Score

10.1503/cmaj.190757

Authors: R. Payne, S. Mendonca, M. Elliott, C. Saunders, D. Edwards, M. Marshall, M. Roland

2020

Eleven-year multimorbidity burden among 637 255 people with and without type 2 diabetes: a population-based study using primary care and linked hospitalisation data

10.1136/bmjopen-2019-033866

Authors: S. Zghebi, D. Steinke, M. Rutter, D. Ashcroft

2020

Effectiveness of proton pump inhibitors in idiopathic pulmonary fibrosis: a population-based cohort study

10.1016/j.chest.2020.08.2080

Authors: T. Tran, D. Assayag, P. Ernst, S. Suissa

2020

Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease-modifying anti-rheumatic drugs

10.1093/rheumatology/keaa078

Authors: G. Nakafero, M. Grainge, P. Myles, C. Mallen, W. Zhang, M. Doherty, J. Nguyen-Van-Tam, A. Abhishek

2020

The effectiveness of frequent antibiotic use in reducing the risk of infection-related hospital admissions: results from two large population-based cohorts

10.1186/s12916-020-1504-5

Authors: T. van Staa, V. Palin, Y. Li, W. Welfare, T. Felton, P. Dark, D. Ashcroft

2020

Effect of pre-existing conditions on bladder cancer stage at diagnosis: a cohort study using electronic primary care records in the UK

10.3399/bjgp20X710921

Authors: M. Carney, M. Quiroga, L. Mounce, E. Shephard, W. Hamilton, S. Price

2020

The effect of initiation of renin-angiotensin system inhibitors on haemoglobin: A national cohort study

10.1111/bcp.14429

Authors: G. Greenhall, K. Mansfield, D. Nitsch, M. Iwagami, C. Leyrat, R. Johnston, L. Smeeth, L. Tomlinson

2020

The economic burden of infections following intramedullary nailing for a tibial shaft fracture in England

10.1136/bmjopen-2019-035404

Authors: T. Galvain, A. Chitnis, K. Paparouni, C. Tong, C. Holy, P. Giannoudis

2020

Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study

10.1371/journal.pmed.1003432

Authors: M. Pujades-Rodriguez, A. Morgan, R. Cubbon, J. Wu

2020

Disease Activity in Inflammatory Bowel Disease Is Associated With Arterial Vascular Disease

10.1093/ibd/izaa156

Authors: T. Card, E. Zittan, G. Nguyen, M. Grainge

2020

The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study

10.1371/journal.pmed.1003295

Authors: G. Funston, W. Hamilton, G. Abel, E. Crosbie, B. Rous, F. Walter

2020

Development of a structured clinical pharmacology review for specialist support for management of complex polypharmacy in primary care

10.1111/bcp.14243

Authors: C. Threapleton, J. Kimpton, I. Carey, S. DeWilde, D. Cook, T. Harris, E. Baker

2020

Effect of bariatric surgery on long-term cardiovascular outcomes: a nationwide nested cohort study

10.1093/eurheartj/ehaa069

Authors: O. Moussa, M. Ardissino, T. Heaton, A. Tang, O. Khan, P. Ziprin, A. Darzi, P. Collins, S. Purkayastha

2019

Body mass index and Hodgkin\textquoterights lymphoma: UK population-based cohort study of 5.8 million individuals

10.1038/s41416-019-0401-1

Authors: H. Strongman, A. Brown, L. Smeeth, K. Bhaskaran

2019

Cardiovascular and cerebrovascular safety of testosterone replacement therapy among aging men with low testosterone levels: a cohort study.

10.1016/j.amjmed.2019.03.022

Authors: S . Y. Loo, L. Azoulay, R. Nie, S. Dell'Aniello, O. H. Y. Yu, C. Renoux

2019

Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes: A Population-Based Cohort Study Assessing Sex Disparities

10.1161/circulationaha.118.039100

Authors: A. Wright, E. Kontopantelis, R. Emsley, I. Buchan, M. Mamas, N. Sattar, D. Ashcroft, M. Rutter

2019

Changing causes of death for patients with chronic respiratory disease in England, 2005-2015

10.1136/thoraxjnl-2018-212514

Authors: A. Gayle, E. Axson, C. Bloom, V. Navaratnam, J. Quint

2019

The changing face of venous thromboembolism management in England

10.2217/fca-2019-0003

Authors: S. Ramagopalan, R. Carroll, M. Ulvestad, F. Mehmud, R. Alikhan