Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 May 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 203 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



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R. K. Hernandez, Do, T. P., Critchlow, C. W., Dent, R. E., and Jick, S. S., Patient-related risk factors for fracture-healing complications in the United Kingdom General Practice Research Database, Acta Orthop, vol. 83, pp. 653-60, 2012.
L. Li, Roddam, A., Gitlin, M., Taylor, A., Shepherd, S., Shearer, A., and Jick, S., Persistence with osteoporosis medications among postmenopausal women in the UK General Practice Research Database, Menopause, vol. 19, pp. 33-40, 2012.
R. W. Platt, Delaney, J. A., and Suissa, S., The positivity assumption and marginal structural models: the example of warfarin use and risk of bleeding, Eur J Epidemiol, vol. 27, pp. 77-83, 2012.
S. Toovey, Prinssen, E. P., Rayner, C. R., Thakrar, B. T., Dutkowski, R., Koerner, A., Chu, T., Sirzen-Zelenskaya, A., Britschgi, M., Bansod, S., and Donner, B., Post-marketing assessment of neuropsychiatric adverse events in influenza patients treated with oseltamivir: an updated review, Adv Ther, vol. 29, pp. 826-48, 2012.
T. P. Staa, Goldacre, B., Gulliford, M., Cassell, J., Pirmohamed, M., Taweel, A., Delaney, B., and Smeeth, L., Pragmatic randomised trials using routine electronic health records: putting them to the test, Bmj, vol. 344, p. e55, 2012.
P. Ernst, Renoux, C., Dell'Aniello, S., and Suissa, S., Pramipexole use and the risk of pneumonia, BMC Neurol, vol. 12, p. 113, 2012.
N. Shi, Durden, E., Torres, A., Cao, Z., and Happich, M., Predictors of Treatment with Duloxetine or Venlafaxine XR among Adult Patients Treated for Depression in Primary Care Practices in the United Kingdom, Depress Res Treat, vol. 2012, p. 815363, 2012.
H. J. Forbes, Thomas, S. L., Smeeth, L., and Langan, S. M., Prescription of antiviral therapy after herpes zoster in general practice: who receives therapy?, Br J Gen Pract, vol. 62, pp. e808-14, 2012.
M. C. Bradley, Murray, L. J., Cantwell, M. M., and Hughes, C. M., Proton pump inhibitors and histamine-2-receptor antagonists and pancreatic cancer risk: a nested case-control study, Br J Cancer, vol. 106, pp. 233-9, 2012.
C. E. Leonard, Freeman, C. P., Newcomb, C. W., Reese, P. P., Herlim, M., Bilker, W. B., Hennessy, S., and Strom, B. L., Proton pump inhibitors and traditional nonsteroidal anti-inflammatory drugs and the risk of acute interstitial nephritis and acute kidney injury, Pharmacoepidemiol Drug Saf, vol. 21, pp. 1155-72, 2012.
S. Toovey, Jick, S. S., and Meier, C. R., Parkinson's disease or Parkinson symptoms following seasonal influenza, Influenza Other Respir Viruses, vol. 5, pp. 328-33, 2011.
A. Dregan, Grieve, A., Van Staa, T., and Gulliford, M. C., Potential application of item-response theory to interpretation of medical codes in electronic patient records, BMC Med Res Methodol, vol. 11, p. 168, 2011.
J. A. Hodgkinson, Taylor, C. J., and Hobbs, F. D., Predictors of incident atrial fibrillation and influence of medications: a retrospective case-control study, Br J Gen Pract, vol. 61, pp. e353-61, 2011.
R. L. DiSantostefano and Davis, K. J., Prescription patterns in asthma patients initiating salmeterol in UK general practice: a retrospective cohort study using the General Practice Research Database (GPRD), Drug Saf, vol. 34, pp. 511-20, 2011.
W. Gao, Gulliford, M., and Higginson, I. J., Prescription patterns of analgesics in the last 3 months of life: a retrospective analysis of 10202 lung cancer patients, Br J Cancer, vol. 104, pp. 1704-10, 2011.
D. Bennett, Hodgson, M. E., Shukla, A., and Logie, J. W., Prevalence of diagnosed adult immune thrombocytopenia in the United Kingdom, Adv Ther, vol. 28, pp. 1096-104, 2011.
N. F. Khan, Watson, E., and Rose, P. W., Primary care consultation behaviours of long-term, adult survivors of cancer in the UK, Br J Gen Pract, vol. 61, pp. 197-9, 2011.
N. N. Mehta, Azfar, R. S., Shin, D. B., Neimann, A. L., Troxel, A. B., and Gelfand, J. M., Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database, Eur Heart J, vol. 31, pp. 1000-6, 2010.
C. J. Girman, Kou, T. D., Cai, B., Alexander, C. M., O'Neill, E. A., Williams-Herman, D. E., and Katz, L., Patients with type 2 diabetes mellitus have higher risk for acute pancreatitis compared with those without diabetes, Diabetes Obes Metab, vol. 12, pp. 766-71, 2010.
M. Egbring, Kullak-Ublick, G. A., and Russmann, S., Phynx: an open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases, Pharmacoepidemiol Drug Saf, vol. 19, pp. 38-44, 2010.
M. Thomas, Murray-Thomas, T., Fan, T., Williams, T., and Taylor, S., Prescribing patterns of asthma controller therapy for children in UK primary care: a cross-sectional observational study, BMC Pulm Med, vol. 10, p. 29, 2010.
S. Johansson, Wallander, M. A., de Abajo, F. J., and Rodriguez, L. A. Garcia, Prospective drug safety monitoring using the UK primary-care General Practice Research Database: theoretical framework, feasibility analysis and extrapolation to future scenarios, Drug Saf, vol. 33, pp. 223-32, 2010.
B. Zhang, de Vries, F., Setakis, E., and van Staa, T. P., The pattern of risk of myocardial infarction in patients taking asthma medication: a study with the General Practice Research Database, J Hypertens, vol. 27, pp. 1485-92, 2009.
C. Millett, Bottle, A., Ng, A., Curcin, V., Molokhia, M., Saxena, S., and Majeed, A., Pay for perfomance and the quality of diabetes management in individuals with and without co-morbid medical conditions, J R Soc Med, vol. 102, pp. 369-77, 2009.
D. J. Humes, Solaymani-Dodaran, M., Fleming, K. M., Simpson, J., Spiller, R. C., and West, J., A population-based study of perforated diverticular disease incidence and associated mortality, Gastroenterology, vol. 136, pp. 1198-205, 2009.
S. Rietbrock, Olson, M., and van Staa, T. P., The potential effects on fracture outcomes of improvements in persistence and compliance with bisphosphonates, Qjm, vol. 102, pp. 35-42, 2009.
S. Turner, Thomas, M., von Ziegenweidt, J., and Price, D., Prescribing trends in asthma: a longitudinal observational study, Arch Dis Child, vol. 94, pp. 16-22, 2009.
R. A. Watts, Al-Taiar, A., Scott, D. G., and Macgregor, A. J., Prevalence and incidence of Wegener's granulomatosis in the UK general practice research database, Arthritis Rheum, vol. 61, pp. 1412-6, 2009.
H. Phatak, Wentworth, C., Sazonov, V., and Burke, T., Prevalence and predictors of lipid abnormalities in patients treated with statins in the UK general practice, Atherosclerosis, vol. 202, pp. 225-33, 2009.
C. Martinez, Sullivan, T., and Hauser, W. A., Prevalence of acute repetitive seizures (ARS) in the United Kingdom, Epilepsy Res, vol. 87, pp. 137-43, 2009.
H. E. Evans, Tsourapas, A., Mercer, C. H., Rait, G., Bryan, S., Hamill, M., Delpech, V., Hughes, G., Brook, G., Williams, T., Johnson, A. M., Singh, S., Petersen, I., Chadborn, T., and Cassell, J. A., Primary care consultations and costs among HIV-positive individuals in UK primary care 1995-2005: a cohort study, Sex Transm Infect, vol. 85, pp. 543-9, 2009.
Y. B. Brauchli, Jick, S. S., Miret, M., and Meier, C. R., Psoriasis and risk of incident cancer: an inception cohort study with a nested case-control analysis, J Invest Dermatol, vol. 129, pp. 2604-12, 2009.
Y. B. Brauchli, Jick, S. S., Miret, M., and Meier, C. R., Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis, Br J Dermatol, vol. 160, pp. 1048-56, 2009.
[Page last reviewed 5 May 2020]