Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 May 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 3MB, 203 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 2509 results:
Author Title Type [ Year(Asc)]
A. J. Apter, Kinman, J. L., Bilker, W. B., Herlim, M., Margolis, D. J., Lautenbach, E., Hennessy, S., and Strom, B. L., Is there cross-reactivity between penicillins and cephalosporins?, Am J Med, vol. 119, pp. 354.e11-9, 2006.
J. A. Cassell, Mercer, C. H., Sutcliffe, L., Petersen, I., Islam, A., Brook, M. G., Ross, J. D., Kinghorn, G. R., Simms, I., Hughes, G., Majeed, A., Stephenson, J. M., Johnson, A. M., and Hayward, A. C., Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database, Bmj, vol. 332, pp. 332-4, 2006.
A. Gonzalez-Perez and Rodriguez, L. A., Upper gastrointestinal complications among users of paracetamol, Basic Clin Pharmacol Toxicol, vol. 98, pp. 297-303, 2006.
P. C. Souverein, Webb, D. J., Weil, J. G., van Staa, T. P., and Egberts, A. C., Use of antiepileptic drugs and risk of fractures: case-control study among patients with epilepsy, Neurology, vol. 66, pp. 1318-24, 2006.
F. Andersohn, Suissa, S., and Garbe, E., Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction, Circulation, vol. 113, pp. 1950-7, 2006.
T. P. van Staa, Card, T., Logan, R. F., and Leufkens, H. G., 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study, Gut, vol. 54, pp. 1573-8, 2005.
D. J. Margolis, Bowe, W. P., Hoffstad, O., and Berlin, J. A., Antibiotic treatment of acne may be associated with upper respiratory tract infections, Arch Dermatol, vol. 141, pp. 1132-6, 2005.
F. N. Aberra, Brensinger, C. M., Bilker, W. B., Lichtenstein, G. R., and Lewis, J. D., Antibiotic use and the risk of flare of inflammatory bowel disease, Clin Gastroenterol Hepatol, vol. 3, pp. 459-65, 2005.
J. A. Kaye and Jick, H., Antibiotics and the risk of breast cancer, Epidemiology, vol. 16, pp. 688-90, 2005.
C. Martinez, Rietbrock, S., Wise, L., Ashby, D., Chick, J., Moseley, J., Evans, S., and Gunnell, D., Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study, Bmj, vol. 330, p. 389, 2005.
S. Maru, Koch, G. G., Stender, M., Clark, D., Gibowski, L., Petri, H., White, A. D., and Simpson, Jr., R. J., Antidiabetic drugs and heart failure risk in patients with type 2 diabetes in the U.K. primary care setting, Diabetes Care, vol. 28, pp. 20-6, 2005.
C. E. Koro, Bowlin, S. J., and Weiss, S. R., Antidiabetic therapy and the risk of heart failure in type 2 diabetic patients: an independent effect or confounding by indication, Pharmacoepidemiol Drug Saf, vol. 14, pp. 697-703, 2005.
N. Dunn, Mullee, M., Perry, V. H., and Holmes, C., Association between dementia and infectious disease: evidence from a case-control study, Alzheimer Dis Assoc Disord, vol. 19, pp. 91-4, 2005.
A. Lawson, West, J., Aithal, G. P., and Logan, R. F., Autoimmune cholestatic liver disease in people with coeliac disease: a population-based study of their association, Aliment Pharmacol Ther, vol. 21, pp. 401-5, 2005.
A. Gonzalez-Perez and Rodriguez, L. A. Garcia, Breast cancer risk among users of antidepressant medications, Epidemiology, vol. 16, pp. 101-5, 2005.
L. Smeeth, Cook, C., Chakravarthy, U., Hubbard, R., and Fletcher, A. E., A case control study of age related macular degeneration and use of statins, Br J Ophthalmol, vol. 89, pp. 1171-5, 2005.
C. O. Sullivan, Omar, R. Z., Ambler, G., and Majeed, A., Case-mix and variation in specialist referrals in general practice, Br J Gen Pract, vol. 55, pp. 529-33, 2005.
C. Black, Kaye, J. A., and Jick, H., Cesarean delivery in the United Kingdom: time trends in the general practice research database, Obstet Gynecol, vol. 106, pp. 151-5, 2005.
C. J. Edwards, Arden, N. K., Fisher, D., Saperia, J. C., Reading, I., van Staa, T. P., and Cooper, C., The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from the United Kingdom General Practice Research Database, Rheumatology (Oxford), vol. 44, pp. 1394-8, 2005.
T. Shao and Yang, Y. X., Cholecystectomy and the risk of colorectal cancer, Am J Gastroenterol, vol. 100, pp. 1813-20, 2005.
M. A. Hernan, Jick, S. S., Logroscino, G., Olek, M. J., Ascherio, A., and Jick, H., Cigarette smoking and the progression of multiple sclerosis, Brain, vol. 128, pp. 1461-5, 2005.
D. M. Fleming, Ross, A. M., Cross, K. W., Kendall, H., and Elliot, A. J., Concerning: 'Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database', J Public Health (Oxf), vol. 27, pp. 228-9; author reply 229-31, 2005.
L. M. Fischer, Schlienger, R. G., Matter, C. M., Jick, H., and Meier, C. R., Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction, Pharmacotherapy, vol. 25, pp. 503-10, 2005.
N. Dunn, Holmes, C., and Mullee, M., Does lithium therapy protect against the onset of dementia?, Alzheimer Dis Assoc Disord, vol. 19, pp. 20-2, 2005.
C. Gasse, Hollowell, J., Meier, C. R., and Haefeli, W. E., Drug interactions and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation treated with warfarin, Thromb Haemost, vol. 94, pp. 537-43, 2005.
A. Ruigomez, Rodriguez, L. A., Wallander, M. A., Johansson, S., Thomas, M., and Price, D., Gastroesophageal reflux disease and asthma: a longitudinal study in UK general practice, Chest, vol. 128, pp. 85-93, 2005.
L. J. Tata, West, J., Smith, C., Farrington, P., Card, T., Smeeth, L., and Hubbard, R., General population based study of the impact of tricyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction, Heart, vol. 91, pp. 465-71, 2005.
M. N. Cook, Girman, C. J., Stein, P. P., Alexander, C. M., and Holman, R. R., Glycemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes, Diabetes Care, vol. 28, pp. 995-1000, 2005.
T. R. Mikuls, Farrar, J. T., Bilker, W. B., Fernandes, S., Schumacher, Jr., H. R., and Saag, K. G., Gout epidemiology: results from the UK General Practice Research Database, 1990-1999, Ann Rheum Dis, vol. 64, pp. 267-72, 2005.
F. de Giuli, Khaw, K. T., Cowie, M. R., Sutton, G. C., Ferrari, R., and Poole-Wilson, P. A., Incidence and outcome of persons with a clinical diagnosis of heart failure in a general practice population of 696,884 in the United Kingdom, Eur J Heart Fail, vol. 7, pp. 295-302, 2005.
P. C. Souverein, Webb, D. J., Petri, H., Weil, J., van Staa, T. P., and Egberts, T., Incidence of fractures among epilepsy patients: a population-based retrospective cohort study in the General Practice Research Database, Epilepsia, vol. 46, pp. 304-10, 2005.
J. Logie, Clifford, G. M., and Farmer, R. D., Incidence, prevalence and management of lower urinary tract symptoms in men in the UK, BJU Int, vol. 95, pp. 557-62, 2005.
G. Gupta, Gelfand, J. M., and Lewis, J. D., Increased risk for demyelinating diseases in patients with inflammatory bowel disease, Gastroenterology, vol. 129, pp. 819-26, 2005.
M. C. Gulliford, Charlton, J., and Latinovic, R., Increased utilization of primary care 5 years before diagnosis of type 2 diabetes: a matched cohort study, Diabetes Care, vol. 28, pp. 47-52, 2005.
C. Joseph, Goddard, N., and Gelb, D., Influenza vaccine uptake and distribution in England and Wales using data from the General Practice Research Database, 1989/90-2003/04, J Public Health (Oxf), vol. 27, pp. 371-7, 2005.
V. A. Kiri, Bettoncelli, G., Testi, R., and Viegi, G., Inhaled corticosteroids are more effective in COPD patients when used with LABA than with SABA, Respir Med, vol. 99, pp. 1115-24, 2005.
V. A. Kiri, Pride, N. B., Soriano, J. B., and Vestbo, J., Inhaled corticosteroids in chronic obstructive pulmonary disease: results from two observational designs free of immortal time bias, Am J Respir Crit Care Med, vol. 172, pp. 460-4, 2005.
M. C. Gulliford, Adams, G., Ukoumunne, O. C., Latinovic, R., Chinn, S., and Campbell, M. J., Intraclass correlation coefficient and outcome prevalence are associated in clustered binary data, J Clin Epidemiol, vol. 58, pp. 246-51, 2005.
M. Solaymani-Dodaran, Logan, R. F., West, J., and Card, T., Mortality associated with Barrett's esophagus and gastroesophageal reflux disease diagnoses-a population-based cohort study, Am J Gastroenterol, vol. 100, pp. 2616-21, 2005.
R. Ryan, Newnham, A., Khunti, K., and Majeed, A., New cases of diabetes mellitus in England and Wales, 1994-1998: database study, Public Health, vol. 119, pp. 892-9, 2005.
G. M. Clifford, Logie, J., and Farmer, R. D., No risk of drug-associated liver injury with alpha1-adrenoreceptor blocking agents in men with BPH: results from an observational study using the GPRD, Pharmacoepidemiol Drug Saf, vol. 14, pp. 75-80, 2005.
C. Huerta, Castellsague, J., Varas-Lorenzo, C., and Rodriguez, L. A. Garcia, Nonsteroidal anti-inflammatory drugs and risk of ARF in the general population, Am J Kidney Dis, vol. 45, pp. 531-9, 2005.
B. D. Bradbury, Wilk, J. B., and Kaye, J. A., Obesity and the risk of prostate cancer (United States), Cancer Causes Control, vol. 16, pp. 637-41, 2005.
L. Watson, Kerstjens, H. A., Rabe, K. F., Kiri, V., Visick, G. T., and Postma, D. S., Obtaining optimal control in mild asthma: theory and practice, Fam Pract, vol. 22, pp. 305-10, 2005.
J. B. Soriano, Visick, G. T., Muellerova, H., Payvandi, N., and Hansell, A. L., Patterns of comorbidities in newly diagnosed COPD and asthma in primary care, Chest, vol. 128, pp. 2099-107, 2005.
A. Ruigomez, Johansson, S., Wallander, M. A., and Rodriguez, L. A. Garcia, Predictors and prognosis of paroxysmal atrial fibrillation in general practice in the UK, BMC Cardiovasc Disord, vol. 5, p. 20, 2005.
J. M. Gelfand, Weinstein, R., Porter, S. B., Neimann, A. L., Berlin, J. A., and Margolis, D. J., Prevalence and treatment of psoriasis in the United Kingdom: a population-based study, Arch Dermatol, vol. 141, pp. 1537-41, 2005.
D. Mines, Hill, D., Yu, H., and Novelli, L., Prevalence of risk factors for suicide in patients prescribed venlafaxine, fluoxetine, and citalopram, Pharmacoepidemiol Drug Saf, vol. 14, pp. 367-72, 2005.
A. G. Wade, Toumi, I., and Hemels, M. E., A probabilistic cost-effectiveness analysis of escitalopram, generic citalopram and venlafaxine as a first-line treatment of major depressive disorder in the UK, Curr Med Res Opin, vol. 21, pp. 631-42, 2005.
W. T. Hamilton, Gallagher, A. M., Thomas, J. M., and White, P. D., The prognosis of different fatigue diagnostic labels: a longitudinal survey, Fam Pract, vol. 22, pp. 383-8, 2005.
[Page last reviewed 5 May 2020]