Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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Author [ Title(Desc)] Type Year
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S. H. Landis, Wurst, K., Le, H. V., Bonar, K., and Punekar, Y. S., Can Assessment of Disease Burden Prior to Changes in Initial COPD Maintenance Treatment Provide Insight into Remaining Unmet Needs? A Retrospective Database Study in UK Primary Care, Copd, vol. 14, pp. 80-85, 2017.
V. M. Walker, Davies, N. M., Jones, T., Kehoe, P. G., and Martin, R. M., Can commonly prescribed drugs be repurposed for the prevention or treatment of Alzheimer's and other neurodegenerative diseases? Protocol for an observational cohort study in the UK Clinical Practice Research Datalink, BMJ Open, vol. 6, p. e012044, 2016.
E. S. Petherick, Pickett, K. E., and Cullum, N. A., Can different primary care databases produce comparable estimates of burden of disease: results of a study exploring venous leg ulceration, Fam Pract, vol. 32, pp. 374-80, 2015.
F. A. Pearce, Hubbard, R. B., Grainge, M. J., Watts, R. A., Abhishek, A., and Lanyon, P. C., Can granulomatosis with polyangiitis be diagnosed earlier in primary care? A case-control study, Qjm, vol. 111, pp. 39-45, 2018.
S. F. Weng, Reps, J., Kai, J., Garibaldi, J. M., and Qureshi, N., Can machine-learning improve cardiovascular risk prediction using routine clinical data?, PLoS One, vol. 12, p. e0174944, 2017.
C. A. Bannister, Holden, S. E., Jenkins-Jones, S., Morgan, C. L., Halcox, J. P., Schernthaner, G., Mukherjee, J., and Currie, C. J., Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls, Diabetes Obes Metab, vol. 16, pp. 1165-73, 2014.
A. Macfarlane, Hockley, C., McCandlish, R., and McNiece, R., Can the General Practice Research Database be used to monitor the health of babies and their mothers?, Health Stat Q, pp. 5-15, 2002.
A. Judge, Wallace, G., Prieto-Alhambra, D., Arden, N. K., and Edwards, C. J., Can the publication of guidelines change the management of early rheumatoid arthritis? An interrupted time series analysis from the United Kingdom, Rheumatology (Oxford), vol. 54, pp. 2244-8, 2015.
S. Muller, Hider, S. L., Belcher, J., Helliwell, T., and Mallen, C. D., Is cancer associated with polymyalgia rheumatica? A cohort study in the General Practice Research Database, Ann Rheum Dis, vol. 73, pp. 1769-73, 2014.
C. Tsang, Bottle, A., Majeed, A., and Aylin, P., Cancer diagnosed by emergency admission in England: an observational study using the general practice research database, BMC Health Serv Res, vol. 13, p. 308, 2013.
J. A. Kaye, Margulis, A. V., Fortuny, J., McQuay, L. J., Plana, E., Bartsch, J. L., Bui, C. L., Perez-Gutthann, S., and Arana, A., Cancer Incidence after Initiation of Antimuscarinic Medications for Overactive Bladder in the United Kingdom: Evidence for Protopathic Bias, Pharmacotherapy, vol. 37, pp. 673-683, 2017.
E. Ankus, Price, S. J., Ukoumunne, O. C., Hamilton, W., and Bailey, S. E. R., Cancer incidence in patients with a high normal platelet count: a cohort study using primary care data, Fam Pract, vol. 35, pp. 671-675, 2018.
R. Boggon, van Staa, T. P., Chapman, M., Gallagher, A. M., Hammad, T. A., and Richards, M. A., Cancer recording and mortality in the General Practice Research Database and linked cancer registries, Pharmacoepidemiol Drug Saf, vol. 22, pp. 168-75, 2013.
R. Williams, van Staa, T. P., Gallagher, A. M., Hammad, T., Leufkens, H. G. M., and de Vries, F., Cancer recording in patients with and without type 2 diabetes in the Clinical Practice Research Datalink primary care data and linked hospital admission data: a cohort study, BMJ Open, vol. 8, p. e020827, 2018.
A. But, De Bruin, M. L., Bazelier, M. T., Hjellvik, V., Andersen, M., Auvinen, A., Starup-Linde, J., Schmidt, M. K., Furu, K., de Vries, F., Karlstad, O., Ekstrom, N., and Haukka, J., Cancer risk among insulin users: comparing analogues with human insulin in the CARING five-country cohort study, Diabetologia, vol. 60, pp. 1691-1703, 2017.
C. Becker, Brobert, G. P., Johansson, S., Jick, S. S., and Meier, C. R., Cancer risk in association with Parkinson disease: a population-based study, Parkinsonism Relat Disord, vol. 16, pp. 186-90, 2010.
R. Alsaggaf, St George, D. M. M., Zhan, M., Pfeiffer, R. M., Wang, Y., Wagner, K. R., Greene, M. H., Amr, S., and Gadalla, S. M., Cancer Risk in Myotonic Dystrophy Type I: Evidence of a Role for Disease Severity, JNCI Cancer Spectr, vol. 2, p. pky052, 2018.
G. Singh, Bell, G. S., Driever, P. H., and Sander, J. W., Cancer risk in people with epilepsy using valproate-sodium, Acta Neurol Scand, vol. 125, pp. 234-40, 2012.
S. Couraud, Dell'Aniello, S., Bouganim, N., and Azoulay, L., Cardiac glycosides and the risk of breast cancer in women with chronic heart failure and supraventricular arrhythmia, Breast Cancer Res Treat, vol. 146, pp. 619-26, 2014.
S. Couraud, Azoulay, L., Dell'Aniello, S., and Suissa, S., Cardiac glycosides use and the risk of lung cancer: a nested case-control study, BMC Cancer, vol. 14, p. 573, 2014.
S. Hernandez-Diaz and Rodriguez, L. A. Garcia, Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications, BMC Med, vol. 4, p. 22, 2006.
S. Y. Loo, Azoulay, L., Nie, R., Dell'Aniello, S., Yu, O. H. Y., and Renoux, C., Cardiovascular and cerebrovascular safety of testosterone replacement therapy among aging men with low testosterone levels: a cohort study., Am J Med, 2019.
A. K. Wright, Kontopantelis, E., Emsley, R., Buchan, I. E., Mamas, M. A., Sattar, N., Ashcroft, D. M., and Rutter, M. K., Cardiovascular Risk and Risk Factor Management in Type 2 Diabetes: A Population-Based Cohort Study Assessing Sex Disparities, Circulation, 2019.
L. Wei, Mackenzie, I. S., MacDonald, T. M., and George, J., Cardiovascular risk associated with sodium-containing medicines, Expert Opin Drug Saf, vol. 13, pp. 1515-23, 2014.
J. Dollerup, Vestbo, J., Murray-Thomas, T., Kaplan, A., Martin, R. J., Pizzichini, E., Pizzichini, M. M. M., Burden, A., Martin, J., and Price, D. B., Cardiovascular risks in smokers treated with nicotine replacement therapy: a historical cohort study, Clin Epidemiol, vol. 9, pp. 231-243, 2017.
A. Gilsenan, Fortuny, J., Cainzos-Achirica, M., Cantero, O. F., Flynn, R. W. V., Garcia-Rodriguez, L., Harding, A., Kollhorst, B., Karlsson, P., Linner, L., MacDonald, T. M., Odsbu, I., Plana, E., Ruigomez, A., Schink, T., Ziemiecki, R., and Andrews, E. B., Cardiovascular Safety of Prucalopride in Patients with Chronic Constipation: A Multinational Population-Based Cohort Study, Drug Saf, 2019.
R. Williams, de Vries, F., Kothny, W., Serban, C., Lopez-Leon, S., Chu, C., and Schlienger, R., Cardiovascular safety of vildagliptin in patients with type 2 diabetes: A European multi-database, non-interventional post-authorization safety study, Diabetes Obes Metab, vol. 19, pp. 1473-1478, 2017.
I. Nazareth, King, M., Haines, A., Tai, S. S., and Hall, G., Care of schizophrenia in general practice, Bmj, vol. 307, p. 910, 1993.
I. Nazareth, King, M., and Davies, S., Care of schizophrenia in general practice: the general practitioner and the patient, Br J Gen Pract, vol. 45, pp. 343-7, 1995.
L. Smeeth, Cook, C., Chakravarthy, U., Hubbard, R., and Fletcher, A. E., A case control study of age related macular degeneration and use of statins, Br J Ophthalmol, vol. 89, pp. 1171-5, 2005.
C. Becker, Meier, C. R., Jick, S. S., and Bodmer, M., Case-control analysis on metformin and cancer of the esophagus, Cancer Causes Control, vol. 24, pp. 1763-70, 2013.
L. Smeeth, Hall, A. J., Fombonne, E., Rodrigues, L. C., Huang, X., and Smith, P. G., A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology, BMC Public Health, vol. 1, p. 2, 2001.
I. J. Douglas, Cook, C., Chakravarthy, U., Hubbard, R., Fletcher, A. E., and Smeeth, L., A case-control study of drug risk factors for age-related macular degeneration, Ophthalmology, vol. 114, pp. 1164-9, 2007.
C. O. Sullivan, Omar, R. Z., Ambler, G., and Majeed, A., Case-mix and variation in specialist referrals in general practice, Br J Gen Pract, vol. 55, pp. 529-33, 2005.
L. Smeeth, Hubbard, R., and Fletcher, A. E., Cataract and the use of statins: a case-control study, Qjm, vol. 96, pp. 337-43, 2003.
C. Becker, Schneider, C., Aballea, S., Bailey, C., Bourne, R., Jick, S., and Meier, C., Cataract in patients with diabetes mellitus-incidence rates in the UK and risk factors, Eye (Lond), vol. 32, pp. 1028-1035, 2018.
A. Lalmohamed, Bazelier, M. T., van Staa, T. P., Uitdehaag, B. M., Leufkens, H. G., de Boer, A., and de Vries, F., Causes of death in patients with multiple sclerosis and matched referent subjects: a population-based cohort study, Eur J Neurol, vol. 19, pp. 1007-14, 2012.
A. A. Sultan, Crooks, C. J., Card, T., Tata, L. J., Fleming, K. M., and West, J., Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis, Gut, vol. 64, pp. 1220-6, 2015.
K. Abuabara, Azfar, R. S., Shin, D. B., Neimann, A. L., Troxel, A. B., and Gelfand, J. M., Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K, Br J Dermatol, vol. 163, pp. 586-92, 2010.
M. Solaymani-Dodaran, Card, T. R., and West, J., Cause-specific mortality of people with Barrett's esophagus compared with the general population: a population-based cohort study, Gastroenterology, vol. 144, pp. 1375-83, 1383.e1, 2013.
C. Black, Kaye, J. A., and Jick, H., Cesarean delivery in the United Kingdom: time trends in the general practice research database, Obstet Gynecol, vol. 106, pp. 151-5, 2005.
I. C. Wong, Asherson, P., Bilbow, A., Clifford, S., Coghill, D., DeSoysa, R., Hollis, C., McCarthy, S., Murray, M., Planner, C., Potts, L., Sayal, K., and Taylor, E., Cessation of attention deficit hyperactivity disorder drugs in the young (CADDY)–a pharmacoepidemiological and qualitative study, Health Technol Assess, vol. 13, pp. iii-iv, ix-xi, 1-120, 2009.
M. A. C. Tanke, Feyman, Y., Bernal-Delgado, E., Deeny, S. R., Imanaka, Y., Jeurissen, P., Lange, L., Pimperl, A., Sasaki, N., Schull, M., Wammes, J. J. G., Wodchis, W. P., and Meyer, G. S., A challenge to all. A primer on inter-country differences of high-need, high-cost patients, PLoS One, vol. 14, p. e0217353, 2019.
M. Smith, Herrington, W. G., Weldegiorgis, M., Hobbs, F. R., Bankhead, C., and Woodward, M., Change in Albuminuria and Risk of Renal and Cardiovascular Outcomes: Natural Variation Should Be Taken into Account, Kidney Int Rep, vol. 3, pp. 939-949, 2018.
J. A. Kaye, Bradbury, B. D., and Jick, H., Changes in antipsychotic drug prescribing by general practitioners in the United Kingdom from 1991 to 2000: a population-based observational study, Br J Clin Pharmacol, vol. 56, pp. 569-75, 2003.
J. P. H. Wilding, Godec, T., Khunti, K., Pocock, S., Fox, R., Smeeth, L., Clauson, P., Fenici, P., Hammar, N., and Medina, J., Changes in HbA1c and weight after initiation of second-line therapy in patients with type 2 diabetes in clinical practice., Diabetologia., vol. 60, p. S301, 2017.
J. Wilding, Godec, T., Khunti, K., Pocock, S., Fox, R., Smeeth, L., Clauson, P., Fenici, P., Hammar, N., and Medina, J., Changes in HbA1c and weight, and treatment persistence, over the 18 months following initiation of second-line therapy in patients with type 2 diabetes: results from the United Kingdom Clinical Practice Research Datalink, BMC Med, vol. 16, p. 116, 2018.
D. Prieto-Alhambra, Javaid, M. K., Maskell, J., Judge, A., Nevitt, M., Cooper, C., and Arden, N. K., Changes in hip fracture rate before and after total knee replacement due to osteoarthritis: a population-based cohort study, Ann Rheum Dis, vol. 70, pp. 134-8, 2011.
E. Setakis, Leufkens, H. G., and van Staa, T. P., Changes in the characteristics of patients prescribed selective cyclooxygenase 2 inhibitors after the 2004 withdrawal of rofecoxib, Arthritis Rheum, vol. 59, pp. 1105-11, 2008.
J. K. Quint, Millett, E. R., Joshi, M., Navaratnam, V., Thomas, S. L., Hurst, J. R., Smeeth, L., and Brown, J. S., Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study, Eur Respir J, vol. 47, pp. 186-93, 2016.
[Page last reviewed 4 November 2019]