Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 November 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


(PDF, 3MB, 192 pages)


Export 2365 results:
Author Title Type [ Year(Desc)]
P. D. van der Linden, Sturkenboom, M. C., Herings, R. M., Leufkens, H. M., Rowlands, S., and Stricker, B. H., Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids, Arch Intern Med, vol. 163, pp. 1801-7, 2003.
J. B. Soriano, Kiri, V. A., Maier, W. C., and Strachan, D., Increasing prevalence of asthma in UK primary care during the 1990s, Int J Tuberc Lung Dis, vol. 7, pp. 415-21, 2003.
C. C. Yang, Jick, S. S., and Jick, H., Lipid-lowering drugs and the risk of depression and suicidal behavior, Arch Intern Med, vol. 163, pp. 1926-32, 2003.
J. M. Gelfand, Berlin, J., Van Voorhees, A., and Margolis, D. J., Lymphoma rates are low but increased in patients with psoriasis: results from a population-based cohort study in the United Kingdom, Arch Dermatol, vol. 139, pp. 1425-9, 2003.
D. J. Margolis, Knauss, J., Bilker, W., and Baumgarten, M., Medical conditions as risk factors for pressure ulcers in an outpatient setting, Age Ageing, vol. 32, pp. 259-64, 2003.
L. M. Howard, Goss, C., Leese, M., and Thornicroft, G., Medical outcome of pregnancy in women with psychotic disorders and their infants in the first year after birth, Br J Psychiatry, vol. 182, pp. 63-7, 2003.
C. Black, Kaye, J. A., and Jick, H., MMR vaccine and idiopathic thrombocytopaenic purpura, Br J Clin Pharmacol, vol. 55, pp. 107-11, 2003.
T. Card, Hubbard, R., and Logan, R. F., Mortality in inflammatory bowel disease: a population-based cohort study, Gastroenterology, vol. 125, pp. 1583-90, 2003.
T. P. van Staa, Boulton, F., Cooper, C., Hagenbeek, A., Inskip, H., and Leufkens, H. G., Neutropenia and agranulocytosis in England and Wales: incidence and risk factors, Am J Hematol, vol. 72, pp. 248-54, 2003.
L. A. Garcia Rodriguez and Hernandez-Diaz, S., Nonsteroidal antiinflammatory drugs as a trigger of clinical heart failure, Epidemiology, vol. 14, pp. 240-6, 2003.
L. Smeeth, Boulis, M., Hubbard, R., and Fletcher, A. E., A population based case-control study of cataract and inhaled corticosteroids, Br J Ophthalmol, vol. 87, pp. 1247-51, 2003.
J. Hoare, Bruce, M., and Majeed, A., Prevalence of treated asthma and its management in general practice in England and Wales, 1994–1998, Health Stat Q, vol. 17, pp. 15-22, 2003.
J. B. Soriano, Davis, K. J., Coleman, B., Visick, G., Mannino, D., and Pride, N. B., The proportional Venn diagram of obstructive lung disease: two approximations from the United States and the United Kingdom, Chest, vol. 124, pp. 474-81, 2003.
C. B. Forrest, Majeed, A., Weiner, J. P., Carroll, K., and Bindman, A. B., Referral of children to specialists in the United States and the United kingdom, Arch Pediatr Adolesc Med, vol. 157, pp. 279-85, 2003.
H. E. Seaman, de Vries, C. S., and Farmer, R. D., The risk of liver disorders in women prescribed cyproterone acetate in combination with ethinyloestradiol (Dianette): a nested case-control study using the GPRD, Pharmacoepidemiol Drug Saf, vol. 12, pp. 541-50, 2003.
S. L. Wood, Jick, H., and Sauve, R., The risk of stillbirth in pregnancies before and after the onset of diabetes, Diabet Med, vol. 20, pp. 703-7, 2003.
H. E. Seaman, de Vries, C. S., and Farmer, R. D., The risk of venous thromboembolism in women prescribed cyproterone acetate in combination with ethinyl estradiol: a nested cohort analysis and case-control study, Hum Reprod, vol. 18, pp. 522-6, 2003.
M. B. Toledano, Hansell, A. L., Jarup, L., Quinn, M., Jick, S., and Elliott, P., Temporal trends in orchidopexy, Great Britain, 1992-1998, Environ Health Perspect, vol. 111, pp. 129-32, 2003.
P. C. Souverein, van Staa, T. P., Egberts, A. C., De la Rosette, J. J., Cooper, C., and Leufkens, H. G., Use of alpha-blockers and the risk of hip/femur fractures, J Intern Med, vol. 254, pp. 548-54, 2003.
T. P. van Staa, Cooper, C., Leufkens, H. G., Lammers, J. W., and Suissa, S., The use of inhaled corticosteroids in the United Kingdom and the Netherlands, Respir Med, vol. 97, pp. 578-85, 2003.
C. Huerta, Rodriguez, L. A. Garcia, Wallander, M. A., and Johansson, S., Users of oral steroids are at a reduced risk of developing irritable bowel syndrome, Pharmacoepidemiol Drug Saf, vol. 12, pp. 583-8, 2003.
S. S. Jick, Kaye, J. A., Vasilakis-Scaramozza, C., Rodriguez, L. A. Garcia, Ruigomez, A., Meier, C. R., Schlienger, R. G., Black, C., and Jick, H., Validity of the general practice research database, Pharmacotherapy, vol. 23, pp. 686-9, 2003.
C. C. Yang, Jick, S. S., and Testa, M. A., Who receives lipid-lowering drugs: the effects of comorbidities and patient characteristics on treatment initiation, Br J Clin Pharmacol, vol. 55, pp. 288-98, 2003.
P. Boyle, Roehrborn, C., Harkaway, R., Logie, J., de la Rosette, J., and Emberton, M., 5-Alpha reductase inhibition provides superior benefits to alpha blockade by preventing AUR and BPH-related surgery, Eur Urol, vol. 45, pp. 620-6; discussion 626-7, 2004.
T. P. van Staa, Travis, S., Leufkens, H. G., and Logan, R. F., 5-aminosalicylic acids and the risk of renal disease: a large British epidemiologic study, Gastroenterology, vol. 126, pp. 1733-9, 2004.
F. J. de Abajo, Montero, D., Madurga, M., and Rodriguez, L. A. Garcia, Acute and clinically relevant drug-induced liver injury: a population based case-control study, Br J Clin Pharmacol, vol. 58, pp. 71-80, 2004.
J. D. Lewis and Brensinger, C., Agreement between GPRD smoking data: a survey of general practitioners and a population-based survey, Pharmacoepidemiol Drug Saf, vol. 13, pp. 437-41, 2004.
T. Card, Logan, R. F., Rodrigues, L. C., and Wheeler, J. G., Antibiotic use and the development of Crohn's disease, Gut, vol. 53, pp. 246-50, 2004.
H. Jick, Kaye, J. A., and Jick, S. S., Antidepressants and the risk of suicidal behaviors, Jama, vol. 292, pp. 338-43, 2004.
S. V. Morant, Pettitt, D., MacDonald, T. M., Burke, T. A., and Goldstein, J. L., Application of a propensity score to adjust for channelling bias with NSAIDs, Pharmacoepidemiol Drug Saf, vol. 13, pp. 345-53, 2004.
T. P. van Staa, Bishop, N., Leufkens, H. G., and Cooper, C., Are inhaled corticosteroids associated with an increased risk of fracture in children?, Osteoporos Int, vol. 15, pp. 785-91, 2004.
G. Ronquist, Rodriguez, L. A., Ruigomez, A., Johansson, S., Wallander, M. A., Frithz, G., and Svardsudd, K., Association between captopril, other antihypertensive drugs and risk of prostate cancer, Prostate, vol. 58, pp. 50-6, 2004.
H. Jick and Kaye, J. A., Autism and DPT vaccination in the United Kingdom, N Engl J Med, vol. 350, pp. 2722-3, 2004.
A. Gonzalez-Perez, Ronquist, G., and Rodriguez, L. A. Garcia, Breast cancer incidence and use of antihypertensive medication in women, Pharmacoepidemiol Drug Saf, vol. 13, pp. 581-5, 2004.
P. Mangtani, Cumberland, P., Hodgson, C. R., Roberts, J. A., Cutts, F. T., and Hall, A. J., A cohort study of the effectiveness of influenza vaccine in older people, performed using the United Kingdom general practice research database, J Infect Dis, vol. 190, pp. 1-10, 2004.
S. Hennessy, Bilker, W. B., Knauss, J. S., Kimmel, S. E., Margolis, D. J., Morrison, M. F., Reynolds, R. F., Glasser, D. B., and Strom, B. L., Comparative cardiac safety of low-dose thioridazine and low-dose haloperidol, Br J Clin Pharmacol, vol. 58, pp. 81-7, 2004.
S. De Wilde, Carey, I. M., Bremner, S. A., Richards, N., Hilton, S. R., Strachan, D. P., and Cook, D. G., A comparison of the recording of 30 common childhood conditions in the Doctor's Independent Network and General Practice Research Databases, Health Stat Q, pp. 21-31, 2004.
R. G. Schlienger, Fischer, L. M., Jick, H., and Meier, C. R., Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction, Drug Saf, vol. 27, pp. 1157-65, 2004.
I. M. Carey, Cook, D. G., De Wilde, S., Bremner, S. A., Richards, N., Caine, S., Strachan, D. P., and Hilton, S. R., Developing a large electronic primary care database (Doctors' Independent Network) for research, Int J Med Inform, vol. 73, pp. 443-53, 2004.
L. M. Fischer, Schlienger, R. G., Matter, C. M., Jick, H., and Meier, C. R., Discontinuation of nonsteroidal anti-inflammatory drug therapy and risk of acute myocardial infarction, Arch Intern Med, vol. 164, pp. 2472-6, 2004.
M. L. Murray, de Vries, C. S., and Wong, I. C., A drug utilisation study of antidepressants in children and adolescents using the General Practice Research Database, Arch Dis Child, vol. 89, pp. 1098-102, 2004.
L. M. Fischer, Schlienger, R. G., Matter, C., Jick, H., and Meier, C. R., Effect of rheumatoid arthritis or systemic lupus erythematosus on the risk of first-time acute myocardial infarction, Am J Cardiol, vol. 93, pp. 198-200, 2004.
C. Cooper, Dennison, E. M., Leufkens, H. G., Bishop, N., and van Staa, T. P., Epidemiology of childhood fractures in Britain: a study using the general practice research database, J Bone Miner Res, vol. 19, pp. 1976-81, 2004.
J. A. Kaye and Jick, H., Epidemiology of lower limb fractures in general practice in the United Kingdom, Inj Prev, vol. 10, pp. 368-74, 2004.
D. A. Van De Vijver, Walley, T., and Petri, H., Epidemiology of restless legs syndrome as diagnosed in UK primary care, Sleep Med, vol. 5, pp. 435-40, 2004.
A. Gaitatzis, Carroll, K., Majeed, A., and W. J, S., The epidemiology of the comorbidity of epilepsy in the general population, Epilepsia, vol. 45, pp. 1613-22, 2004.
T. Card, West, J., Hubbard, R., and Logan, R. F., Hip fractures in patients with inflammatory bowel disease and their relationship to corticosteroid use: a population based cohort study, Gut, vol. 53, pp. 251-5, 2004.
B. D. Bradbury and Jick, H., In vitro fertilization and childhood retinoblastoma, Br J Clin Pharmacol, vol. 58, pp. 209-11, 2004.
H. Jick, Kaye, J. A., and Black, C., Incidence and prevalence of drug-treated attention deficit disorder among boys in the UK, Br J Gen Pract, vol. 54, pp. 345-7, 2004.
A. M. Gallagher, Thomas, J. M., Hamilton, W. T., and White, P. D., Incidence of fatigue symptoms and diagnoses presenting in UK primary care from 1990 to 2001, J R Soc Med, vol. 97, pp. 571-5, 2004.
[Page last reviewed 4 November 2019]