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UK data driving real-world evidence
Bibliography
Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 April 2021) and papers are listed below and in the PDF below.
If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.
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(PDF, 5MB, 226 pages)This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website.
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“Antibiotic use and serious complications following acute otitis media and acute sinusitis: a retrospective cohort study”, Br J Gen Pract, vol. 70, pp. e255-e263, 2020.
, “Time trends and geographical variation in prescribing of drugs for diabetes in England from 1998 to 2017”, Diabetes Obes Metab, vol. 20, pp. 2159-2168, 2018.
, “Epidemiology of fractures in the United Kingdom 1988-2012: Variation with age, sex, geography, ethnicity and socioeconomic status”, Bone, vol. 87, pp. 19-26, 2016.
, “Time trends in eating disorder incidence”, Br J Psychiatry, vol. 186, pp. 132-5, 2005.
, “Impact of differing glucose-lowering regimens on the pattern of association between glucose control and survival”, Diabetes Obes Metab, vol. 20, pp. 821-830, 2018.
, “Antibiotic treatment failure in four common infections in UK primary care 1991-2012: longitudinal analysis”, Bmj, vol. 349, p. g5493, 2014.
, “Survival as a function of HbA(1c) in people with type 2 diabetes: a retrospective cohort study”, Lancet, vol. 375, pp. 481-9, 2010.
, “Mortality and other important diabetes-related outcomes with insulin vs other antihyperglycemic therapies in type 2 diabetes”, J Clin Endocrinol Metab, vol. 98, pp. 668-77, 2013.
, “Herpes zoster related healthcare burden and costs in immunocompromised (IC) and IC-free populations in England: an observational retrospective database analysis”, BMJ Open, vol. 9, p. e023502, 2019.
, “The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database”, Osteoarthritis Cartilage, vol. 20, pp. 519-24, 2012.
, “Temporal trends in hip and knee replacement in the United Kingdom: 1991 to 2006”, J Bone Joint Surg Br, vol. 92, pp. 130-5, 2010.
, “A population-based survival analysis describing the association of body mass index on time to revision for total hip and knee replacements: results from the UK general practice research database”, BMJ Open, vol. 3, p. e003614, 2013.
, “Future projections of total hip and knee arthroplasty in the UK: results from the UK Clinical Practice Research Datalink”, Osteoarthritis Cartilage, vol. 23, pp. 594-600, 2015.
, “Adjusting for measurement error in baseline prognostic biomarkers included in a time-to-event analysis: a joint modelling approach”, BMC Med Res Methodol, vol. 13, p. 146, 2013.
, “Changes in the pharmacological management of rheumatoid arthritis over two decades”, Rheumatology (Oxford), 2021.
, “The epidemiology of haemochromatosis: a population-based study”, Aliment Pharmacol Ther, vol. 29, pp. 183-92, 2009.
, “A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort”, BMJ Open, vol. 5, p. e007974, 2015.
, “A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink”, Clin Epidemiol, vol. 10, pp. 107-120, 2018.
, “The Use of a Bayesian Hierarchy to Develop and Validate a Co-Morbidity Score to Predict Mortality for Linked Primary and Secondary Care Data from the NHS in England”, PLoS One, vol. 11, p. e0165507, 2016.
, “Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study”, PLoS Med, vol. 10, p. e1001437, 2013.
, “Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding”, Gastroenterology, vol. 144, pp. 1384-93, 1393.e1-2; quiz e18-9, 2013.
, “Defining upper gastrointestinal bleeding from linked primary and secondary care data and the effect on occurrence and 28 day mortality”, BMC Health Serv Res, vol. 12, p. 392, 2012.
, “Glycemic Control and Risk of Infections Among People With Type 1 or Type 2 Diabetes in a Large Primary Care Cohort Study”, Diabetes Care, vol. 41, pp. 2127-2135, 2018.
, “Variability in Glycated Hemoglobin and Risk of Poor Outcomes Among People With Type 2 Diabetes in a Large Primary Care Cohort Study”, Diabetes Care, vol. 42, pp. 2237-2246, 2019.
, “Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study”, Bmj, vol. 360, p. k341, 2018.
, “Hand eczema and steroid-refractory chronic hand eczema in general practice: prevalence and initial treatment”, Br J Dermatol, vol. 176, pp. 955-964, 2017.
, “Cardiac glycosides use and the risk of lung cancer: a nested case-control study”, BMC Cancer, vol. 14, p. 573, 2014.
, “Cardiac glycosides and the risk of breast cancer in women with chronic heart failure and supraventricular arrhythmia”, Breast Cancer Res Treat, vol. 146, pp. 619-26, 2014.
, “Can the Risk of Severe Depression-Related Outcomes be Reduced by Tailoring the Antidepressant Therapy to Patient Characteristics?”, Am J Epidemiol, 2020.
, “The risk of a subsequent cancer diagnosis after herpes zoster infection: primary care database study”, Br J Cancer, vol. 108, pp. 721-6, 2013.
, “Representativeness of a digitally engaged population and a patient organisation population with rheumatoid arthritis and their willingness to participate in research: a cross-sectional study”, RMD Open, vol. 4, p. e000664, 2018.
, “Influenza and Pneumococcal Vaccination Uptake in Patients with Rheumatoid Arthritis Treated with Immunosuppressive Therapy in the UK: A Retrospective Cohort Study Using Data from the Clinical Practice Research Datalink”, PLoS One, vol. 11, p. e0153848, 2016.
, “Glucocorticoid use is associated with an increased risk of hypertension”, Rheumatology (Oxford), 2020.
, “Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK General Practice Research Database”, Bmj, vol. 341, p. c5475, 2010.
, “Validating childhood asthma in an epidemiological study using linked electronic patient records”, BMJ Open, vol. 4, p. e005345, 2014.
, “Socio-economic position and childhood multimorbidity: a study using linkage between the Avon Longitudinal Study of Parents and Children and the General Practice Research Database”, Int J Equity Health, vol. 12, p. 66, 2013.
, “Dental consultations in UK general practice and antibiotic prescribing rates: a retrospective cohort study”, Br J Gen Pract, vol. 66, pp. e329-36, 2016.
, “Prevalence and Incidence Trends for Diagnosed Prescription Opioid Use Disorders in the United Kingdom”, Pain Ther, vol. 6, pp. 73-84, 2017.
, “Ischaemic cardiac events and use of strontium ranelate in postmenopausal osteoporosis: a nested case-control study in the CPRD”, Osteoporos Int, vol. 25, pp. 737-45, 2014.
, “Epidemiology of childhood fractures in Britain: a study using the general practice research database”, J Bone Miner Res, vol. 19, pp. 1976-81, 2004.
, “The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK”, Osteoporos Int, vol. 21, pp. 569-77, 2010.
, “Initial monotherapy with either metformin or sulphonylureas often fails to achieve or maintain current glycaemic goals in patients with Type 2 diabetes in UK primary care”, Diabet Med, vol. 24, pp. 350-8, 2007.
, “Glycemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetes”, Diabetes Care, vol. 28, pp. 995-1000, 2005.
, “Effect of timing and duration of statin exposure on risk of hip or knee revision arthroplasty: a population-based cohort study”, J Rheumatol, 2019.
, “Increased Prevalence of Polyneuropathy in Parkinson's Disease Patients: An Observational Study”, J Parkinsons Dis, vol. 8, pp. 141-144, 2018.
, “Temporal Trends and Patterns in Mortality After Incident Heart Failure: A Longitudinal Analysis of 86000 Individuals”, JAMA Cardiol, 2019.
, “Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients”, PLoS Med, vol. 16, p. e1002805, 2019.
, “Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals”, Lancet, vol. 391, pp. 572-580, 2018.
, “Health care resource use by patients before and after a diagnosis of chronic fatigue syndrome (CFS/ME): a clinical practice research datalink study”, BMC Fam Pract, vol. 18, p. 60, 2017.
, “Trends in the incidence of chronic fatigue syndrome and fibromyalgia in the UK, 2001-2013: a Clinical Practice Research Datalink study”, J R Soc Med, vol. 110, pp. 231-244, 2017.
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