Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 September 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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J. T. Nielen, de Vries, F., Dagnelie, P. C., van den Bemt, B. J., Emans, P. J., Lalmohamed, A., de Boer, A., and Boonen, A., “Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case-control study”, Br J Clin Pharmacol, vol. 81, pp. 370-8, 2016.
T. P. van Staa, Wegman, S., de Vries, F., Leufkens, B., and Cooper, C., “Use of statins and risk of fractures”, Jama, vol. 285, pp. 1850-5, 2001.
A. Tran-Duy, Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F., and de Boer, A., “Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study”, J Intern Med, 2018.
A. Tran-Duy, Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F., and de Boer, A., “Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study”, J Intern Med, vol. 285, pp. 205-214, 2019.
A. Keyany, Nielen, J. T. H., Souverein, P. C., de Vries, F., and van den Bemt, B., “Use of parenteral glucocorticoids and the risk of new onset type 2 diabetes mellitus: A case-control study”, Diabetes Res Clin Pract, vol. 139, pp. 100-106, 2018.
L. M. Knapen, van Dalem, J., Keulemans, Y. C., van Erp, N. P., Bazelier, M. T., De Bruin, M. L., Leufkens, H. G., Croes, S., Neef, C., de Vries, F., and Driessen, J. H., “Use of incretin agents and risk of pancreatic cancer: a population-based cohort study”, Diabetes Obes Metab, vol. 18, pp. 258-65, 2016.
L. M. Knapen, de Jong, R. G., Driessen, J. H., Keulemans, Y. C., van Erp, N. P., De Bruin, M. L., Leufkens, H. G., Croes, S., and de Vries, F., “Use of incretin agents and risk of acute and chronic pancreatitis: A population-based cohort study”, Diabetes Obes Metab, vol. 19, pp. 401-411, 2017.
W. R. der Zanden, de Vries, F., Lalmohamed, A., Driessen, J. H., de Boer, A., Rohde, G., Neef, C., and C. Heijer, den, “Use of Dipeptidyl-Peptidase-4 Inhibitors and the Risk of Pneumonia: A Population-Based Cohort Study”, PLoS One, vol. 10, p. e0139367, 2015.
J. H. Driessen, van Onzenoort, H. A., Henry, R. M., Lalmohamed, A., van den Bergh, J. P., Neef, C., Leufkens, H. G., and de Vries, F., “Use of dipeptidyl peptidase-4 inhibitors for type 2 diabetes mellitus and risk of fracture”, Bone, vol. 68, pp. 124-30, 2014.
F. de Vries, Souverein, P. C., Cooper, C., Leufkens, H. G., and van Staa, T. P., “Use of beta-blockers and the risk of hip/femur fracture in the United Kingdom and The Netherlands”, Calcif Tissue Int, vol. 80, pp. 69-75, 2007.
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R. Y. van der Velde, Wyers, C. E., Teesselink, E., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., Harvey, N. C., and van Staa, T. P., “Trends in oral anti-osteoporosis drug prescription in the United Kingdom between 1990 and 2012: Variation by age, sex, geographic location and ethnicity”, Bone, vol. 94, pp. 50-55, 2017.
O. A. Oshagbemi, Keene, S. J., Driessen, J. H. M., Jordan, R., Wouters, E. F. M., de Boer, A., de Vries, F., and Franssen, F. M. E., “Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013”, Respir Med, vol. 144, pp. 1-6, 2018.
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O. A. Oshagbemi, Burden, A. M., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., Driessen, J. H. M., van der Zee, A. H. Maitlan, de Vries, F., and Franssen, F. M. E., “Stability of Blood Eosinophils in Patients with Chronic Obstructive Pulmonary Disease and in Control Subjects, and the Impact of Sex, Age, Smoking, and Baseline Counts”, Am J Respir Crit Care Med, vol. 195, pp. 1402-1404, 2017.
J. V. Been, Szatkowski, L., van Staa, T. P., Leufkens, H. G., van Schayck, O. C., Sheikh, A., de Vries, F., and Souverein, P., “Smoke-free legislation and the incidence of paediatric respiratory infections and wheezing/asthma: interrupted time series analyses in the four UK nations”, Sci Rep, vol. 5, p. 15246, 2015.
M. T. Bazelier, van Staa, T. P., Uitdehaag, B. M., Cooper, C., Leufkens, H. G., Vestergaard, P., Bentzen, J., and de Vries, F., “A simple score for estimating the long-term risk of fracture in patients with multiple sclerosis”, Neurology, vol. 79, pp. 922-8, 2012.
F. de Vries, van Staa, T. P., Bracke, M. S., Cooper, C., Leufkens, H. G., and Lammers, J. W., “Severity of obstructive airway disease and risk of osteoporotic fracture”, Eur Respir J, vol. 25, pp. 879-84, 2005.
J. T. Nielen, Emans, P. J., Dagnelie, P. C., Boonen, A., Lalmohamed, A., de Boer, A., van den Bemt, B. J., and de Vries, F., “Severity of Diabetes Mellitus and Total Hip or Knee Replacement: A Population-Based Case-Control Study”, Medicine (Baltimore), vol. 95, p. e3739, 2016.
R. Y. van der Velde, Wyers, C. E., Curtis, E. M., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., van Staa, T. P., and Harvey, N. C., “Secular trends in fracture incidence in the UK between 1990 and 2012”, Osteoporos Int, vol. 27, pp. 3197-3206, 2016.
J. T. Nielen, Dagnelie, P. C., Emans, P. J., Veldhorst-Janssen, N., Lalmohamed, A., van Staa, T. P., Boonen, A. E., van den Bemt, B. J., and de Vries, F., “Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements”, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1245-1252, 2016.
R
P. J. Peeters, Bazelier, M. T., Uitdehaag, B. M., Leufkens, H. G., De Bruin, M. L., and de Vries, F., “The risk of venous thromboembolism in patients with multiple sclerosis: the Clinical Practice Research Datalink”, J Thromb Haemost, vol. 12, pp. 444-51, 2014.
L. M. Stolk, de Vries, F., Ebbelaar, C., de Boer, A., Schalekamp, T., Souverein, P., A. Cate-Hoek, T., and Burden, A. M., “Risk of myocardial infarction in patients with atrial fibrillation using vitamin K antagonists, aspirin or direct acting oral anticoagulants”, Br J Clin Pharmacol, vol. 83, pp. 1835-1843, 2017.
E. M. Gieling, van den Ham, H. A., van Onzenoort, H., Bos, J., Kramers, C., de Boer, A., de Vries, F., and Burden, A. M., “Risk of major bleeding and stroke associated with the use of vitamin K antagonists, nonvitamin K antagonist oral anticoagulants and aspirin in patients with atrial fibrillation: a cohort study”, Br J Clin Pharmacol, vol. 83, pp. 1844-1859, 2017.
D. Gibson-Smith, Klop, C., Elders, P. J., Welsing, P. M., van Schoor, N., Leufkens, H. G., Harvey, N. C., van Staa, T. P., and de Vries, F., “The risk of major and any (non-hip) fragility fracture after hip fracture in the United Kingdom: 2000-2010”, Osteoporos Int, vol. 25, pp. 2555-63, 2014.
W. L. Eppenga, Lalmohamed, A., Geerts, A. F., Derijks, H. J., Wensing, M., Egberts, A., De Smet, P. A., and de Vries, F., “Risk of lactic acidosis or elevated lactate concentrations in metformin users with renal impairment: a population-based cohort study”, Diabetes Care, vol. 37, pp. 2218-24, 2014.
B. Spaetgens, de Vries, F., Driessen, J. H. M., Leufkens, H. G., Souverein, P. C., Boonen, A., van der Meer, J. W. M., and Joosten, L. A. B., “Risk of infections in patients with gout: a population-based cohort study”, Sci Rep, vol. 7, p. 1429, 2017.
J. van Dalem, Brouwers, M. C., Stehouwer, C. D., Krings, A., Leufkens, H. G., Driessen, J. H., de Vries, F., and Burden, A. M., “Risk of hypoglycaemia in users of sulphonylureas compared with metformin in relation to renal function and sulphonylurea metabolite group: population based cohort study”, Bmj, vol. 354, p. i3625, 2016.
M. T. Bazelier, de Vries, F., Vestergaard, P., Herings, R. M., Gallagher, A. M., Leufkens, H. G., and van Staa, T. P., “Risk of fracture with thiazolidinediones: an individual patient data meta-analysis”, Front Endocrinol (Lausanne), vol. 4, p. 11, 2013.
S. Pouwels, Bazelier, M. T., de Boer, A., Weber, W. E., Neef, C., Cooper, C., and de Vries, F., “Risk of fracture in patients with Parkinson's disease”, Osteoporos Int, vol. 24, pp. 2283-90, 2013.
S. Pouwels, de Boer, A., Leufkens, H. G., Weber, W. E., Cooper, C., van Onzenoort, H. A., and de Vries, F., “Risk of fracture in patients with muscular dystrophies”, Osteoporos Int, vol. 25, pp. 509-18, 2014.
M. T. Bazelier, Van Staa, T., Uitdehaag, B. M., Cooper, C., Leufkens, H. G., Vestergaard, P., Bentzen, J., and de Vries, F., “The risk of fracture in patients with multiple sclerosis: the UK general practice research database”, J Bone Miner Res, vol. 26, pp. 2271-9, 2011.
S. Pouwels, de Boer, A., Leufkens, H. G., Weber, W. E., Cooper, C., van Staa, T. P., and de Vries, F., “Risk of fracture in patients with Guillain-Barre syndrome”, Osteoporos Int, vol. 25, pp. 1845-51, 2014.
S. Pouwels, de Boer, A., Leufkens, H. G., Weber, W. E., Cooper, C., and de Vries, F., “Risk of fracture in patients with Charcot-Marie-Tooth disease”, Muscle Nerve, vol. 50, pp. 919-24, 2014.
A. Lalmohamed, de Vries, F., Bazelier, M. T., Cooper, A., van Staa, T. P., Cooper, C., and Harvey, N. C., “Risk of fracture after bariatric surgery in the United Kingdom: population based, retrospective cohort study”, Bmj, vol. 345, p. e5085, 2012.
D. C. Braeken, Rohde, G. G., Franssen, F. M., Driessen, J. H., van Staa, T. P., Souverein, P. C., Wouters, E. F., and de Vries, F., “Risk of community-acquired pneumonia in chronic obstructive pulmonary disease stratified by smoking status: a population-based cohort study in the United Kingdom”, Int J Chron Obstruct Pulmon Dis, vol. 12, pp. 2425-2432, 2017.
P. J. Peeters, Bazelier, M. T., Leufkens, H. G., de Vries, F., and De Bruin, M. L., “The risk of colorectal cancer in patients with type 2 diabetes: associations with treatment stage and obesity”, Diabetes Care, vol. 38, pp. 495-502, 2015.
M. T. Bazelier, Mueller-Schotte, S., Leufkens, H. G., Uitdehaag, B. M., Van Staa, T., and de Vries, F., “Risk of cataract and glaucoma in patients with multiple sclerosis”, Mult Scler, vol. 18, pp. 628-38, 2012.
M. E. Goossens, Zeegers, M. P., Bazelier, M. T., De Bruin, M. L., Buntinx, F., and de Vries, F., “Risk of bladder cancer in patients with diabetes: a retrospective cohort study”, BMJ Open, vol. 5, p. e007470, 2015.
J. van Dalem, Brouwers, M., Stehouwer, C. D. A., Krings, A., Klungel, O. H., Driessen, J. H. M., de Vries, F., and Burden, A. M., “Risk of a first-ever acute myocardial infarction and all-cause mortality with sulphonylurea treatment: A population-based cohort study”, Diabetes Obes Metab, vol. 20, pp. 1056-1060, 2018.
J. P. Yska, van Roon, E. N., de Boer, A., Leufkens, H. G., Wilffert, B., de Heide, L. J., de Vries, F., and Lalmohamed, A., “Remission of Type 2 Diabetes Mellitus in Patients After Different Types of Bariatric Surgery: A Population-Based Cohort Study in the United Kingdom”, JAMA Surg, vol. 150, pp. 1126-33, 2015.
F. de Vries, de Vries, C., Cooper, C., Leufkens, B., and van Staa, T. P., “Reanalysis of two studies with contrasting results on the association between statin use and fracture risk: the General Practice Research Database”, Int J Epidemiol, vol. 35, pp. 1301-8, 2006.
Q
A. M. Gallagher, de Vries, F., Plumb, J. M., Hass, B., Clemens, A., and van Staa, T. P., “Quality of INR control and outcomes following venous thromboembolism”, Clin Appl Thromb Hemost, vol. 18, pp. 370-8, 2012.
P
C. Klop, de Vries, F., Bijlsma, J. W., Leufkens, H. G., and Welsing, P. M., “Predicting the 10-year risk of hip and major osteoporotic fracture in rheumatoid arthritis and in the general population: an independent validation and update of UK FRAX without bone mineral density”, Ann Rheum Dis, vol. 75, pp. 2095-2100, 2016.
A. Lalmohamed, Macgregor, A. J., de Vries, F., Leufkens, H. G., and van Staa, T. P., “Patterns of risk of cancer in patients with metal-on-metal hip replacements versus other bearing surface types: a record linkage study between a prospective joint registry and general practice electronic health records in England”, PLoS One, vol. 8, p. e65891, 2013.
H. J. I. De Jong, van Staa, T. P., Lalmohamed, A., de Vries, F., Vandebriel, R. J., Van Loveren, H., Klungel, O. H., and Tervaert, J. W. Cohen, “Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study”, Ann Rheum Dis, vol. 76, pp. 1723-1730, 2017.
H. J. I. De Jong, Tervaert, J. W. Cohen, Lalmohamed, A., de Vries, F., Vandebriel, R. J., Van Loveren, H., Klungel, O. H., and van Staa, T. P., “Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink”, PLoS One, vol. 13, p. e0193297, 2018.
B. Zhang, de Vries, F., Setakis, E., and van Staa, T. P., “The pattern of risk of myocardial infarction in patients taking asthma medication: a study with the General Practice Research Database”, J Hypertens, vol. 27, pp. 1485-92, 2009.
M
C. Klop, Welsing, P. M., Cooper, C., Harvey, N. C., Elders, P. J., Bijlsma, J. W., Leufkens, H. G., and de Vries, F., “Mortality in British hip fracture patients, 2000-2010: a population-based retrospective cohort study”, Bone, vol. 66, pp. 171-7, 2014.
L. Scheepers, Burden, A. M., Arts, I. C. W., Spaetgens, B., Souverein, P., de Vries, F., and Boonen, A., “Medication adherence among gout patients initiated allopurinol: a retrospective cohort study in the Clinical Practice Research Datalink (CPRD)”, Rheumatology (Oxford), vol. 57, pp. 1641-1650, 2018.
L
J. H. Driessen, van den Bergh, J. P., van Onzenoort, H. A., Henry, R. M., Leufkens, H. G., and de Vries, F., “Long-term use of dipeptidyl peptidase-4 inhibitors and risk of fracture: A retrospective population-based cohort study”, Diabetes Obes Metab, vol. 19, pp. 421-428, 2017.
F. de Vries, Setakis, E., Zhang, B., and van Staa, T. P., “Long-acting {beta}2-agonists in adult asthma and the pattern of risk of death and severe asthma outcomes: a study using the GPRD”, Eur Respir J, vol. 36, pp. 494-502, 2010.
[Page last reviewed 6 September 2019]