Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 June 2020) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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 (PDF, 3MB, 205 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website

 

 

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2020
R. Hiramatsu, Iwagami, M., and Nitsch, D., Association between chronic kidney disease and incident diagnosis of dementia in England: a cohort study in Clinical Practice Research Datalink, BMJ Open, vol. 10, p. e033811, 2020.
B. D. Nicholson, Hamilton, W., Koshiaris, C., Oke, J. L., Hobbs, F. D. R., and Aveyard, P., The association between unexpected weight loss and cancer diagnosis in primary care: a matched cohort analysis of 65,000 presentations, Br J Cancer, 2020.
M. Gokhale, Hattori, T., Evitt, L., Lenney, W., Nordstrom, B., Collins, J., Schultze, A., and Van Dyke, M. K., Burden of asthma exacerbations and health care utilization in pediatric patients with asthma in the US and England, Immun Inflamm Dis, 2020.
I. Matthews, Duong, M., Parsons, V. L., Nozad, B., Qizilbash, N., Patel, Y., and Guimicheva, B., Burden of disease from shingles and post-herpetic neuralgia in the over 80 year olds in the UK, PLoS One, vol. 15, p. e0229224, 2020.
S. Borghs, Byram, L., Chan, J., Dedeken, P., Logan, J., Kiri, V., Noack-Rink, M., Patsalos, P. N., and Thieffry, S., Comparing healthcare cost associated with the use of enzyme-inducing and non-enzyme active antiepileptic drugs in elderly patients with epilepsy in the UK: a long-term retrospective, matched cohort study, BMC Neurol, vol. 20, p. 7, 2020.
P. Rockenschaub, Nguyen, V., Aldridge, R. W., Acosta, D., Garcia-Gomez, J. M., and Saez, C., Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015), BMJ Open, vol. 10, p. e034396, 2020.
J. R. Ayala Solares, Raimondi, F. E. Diletta, Zhu, Y., Rahimian, F., Canoy, D., Tran, J., Gomes, A. C. Pinho, Payberah, A. H., Zottoli, M., Nazarzadeh, M., Conrad, N., Rahimi, K., and Salimi-Khorshidi, G., Deep learning for electronic health records: A comparative review of multiple deep neural architectures, J Biomed Inform, vol. 101, p. 103337, 2020.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease-modifying anti-rheumatic drugs, Rheumatology (Oxford), 2020.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease-modifying anti-rheumatic drugs, Rheumatology (Oxford), 2020.
A. Banerjee, Pasea, L., Harris, S., Gonzalez-Izquierdo, A., Torralbo, A., Shallcross, L., Noursadeghi, M., Pillay, D., Sebire, N., Holmes, C., Pagel, C., Wong, W. K., Langenberg, C., Williams, B., Denaxas, S., and Hemingway, H., Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study, Lancet, vol. 395, pp. 1715-1725, 2020.
R. Persson, Lee, S., Yood, M. U., Wagner, M., Minton, N., Niemcryk, S., Lindholm, A., Evans, A., and Jick, S., Incident cardiovascular disease in patients diagnosed with multiple sclerosis: A multi-database study, Mult Scler Relat Disord, vol. 37, p. 101423, 2020.
R. Persson, Lee, S., Yood, M. U., Mc, M. R. Wagner, Minton, N., Niemcryk, S., Lindholm, A., Evans, A. M., and Jick, S., Incident depression in patients diagnosed with multiple sclerosis: a multi-database study, Eur J Neurol, 2020.
R. Persson, Lee, S., M. Yood, U., Mc, C. M. Wagner, Minton, N., Niemcryk, S., Lindholm, A., Evans, A. M., and Jick, S. S., Infections in patients diagnosed with multiple sclerosis: A multi-database study, Mult Scler Relat Disord, vol. 41, p. 101982, 2020.
H. J. L. Heerspink, Karasik, A., Thuresson, M., Melzer-Cohen, C., Chodick, G., Khunti, K., Wilding, J. P. H., Rodriguez, L. A. Garcia, Cea-Soriano, L., Kohsaka, S., Nicolucci, A., Lucisano, G., Lin, F. J., Wang, C. Y., Wittbrodt, E., Fenici, P., and Kosiborod, M., Kidney outcomes associated with use of SGLT2 inhibitors in real-world clinical practice (CVD-REAL 3): a multinational observational cohort study, Lancet Diabetes Endocrinol, vol. 8, pp. 27-35, 2020.
C. W. le Roux, Hartvig, N. V., Haase, C. L., Nordsborg, R. B., Olsen, A. H., and Satylganova, A., Obesity, cardiovascular risk and healthcare resource utilization in the UK, Eur J Prev Cardiol, p. 2047487320925639, 2020.
C. van Durme, Spaetgens, B., Driessen, J., Nielen, J., Sastry, M., Boonen, A., and de Vries, F., Obstructive sleep apnea and the risk of gout: a population-based case-control study, Arthritis Res Ther, vol. 22, p. 92, 2020.
A. Price, Ford, T., Janssens, A., Williams, A. J., and Newlove-Delgado, T., Regional analysis of UK primary care prescribing and adult service referrals for young people with attention-deficit hyperactivity disorder, BJPsych Open, vol. 6, p. e7, 2020.
2019
M. Nowakowska, Van Staa, T., Molter, A., Ashcroft, D. M., Tsang, J. Y., White, A., Welfare, W., and Palin, V., Antibiotic choice in UK general practice: rates and drivers of potentially inappropriate antibiotic prescribing, J Antimicrob Chemother, 2019.
N. S. Nagra, Robinson, D. E., Douglas, I., Delmestri, A., Dakin, S. G., Snelling, S. J. B., Carr, A. J., and Prieto-Alhambra, D., Antibiotic treatment and flares of rheumatoid arthritis: a self-controlled case series study analysis using CPRD GOLD, Sci Rep, vol. 9, p. 8941, 2019.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink, Ann Rheum Dis, 2019.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink, Ann Rheum Dis, 2019.
F. Montastruc, Nie, R., Loo, S., Rej, S., Dell'Aniello, S., Micallef, J., Suissa, S., and Renoux, C., Association of Aripiprazole With the Risk for Psychiatric Hospitalization, Self-harm, or Suicide, JAMA Psychiatry, 2019.
S. Y. Loo, Azoulay, L., Nie, R., Dell'Aniello, S., Yu, O. H. Y., and Renoux, C., Cardiovascular and cerebrovascular safety of testosterone replacement therapy among aging men with low testosterone levels: a cohort study., Am J Med, 2019.
A. V. Gayle, Axson, E. L., Bloom, C. I., Navaratnam, V., and Quint, J. K., Changing causes of death for patients with chronic respiratory disease in England, 2005-2015, Thorax, 2019.
S. Ramtoola, Nyeland, M. E., Jacobsen, J., Ploug, U. J., Kragh, N., and Zimmermann, E., Characteristics of newly diagnosed adults with type 1 diabetes in the UK and evolution of glycaemic control, body mass index and Charlson comorbidity index over the first 5 years after diagnosis, Prim Care Diabetes, 2019.
S. Menon, Nightingale, P., and Trudgill, N., Chronic Obstructive Pulmonary Disease and the Risk of Esophagitis, Barrett Esophagus, and Esophageal Adenocarcinoma: A Primary Care Case-Control Study, J Clin Gastroenterol, 2019.
V. Kuan, Denaxas, S., A Izquierdo, G. -, Direk, K., Bhatti, O., Husain, S., Sutaria, S., Hingorani, M., Nitsch, D., Parisinos, C. A., Lumbers, T., Mathur, R., Sofat, R., Casas, J. P., Wong, I. C. K., Hemingway, H., and Hingorani, A. D., A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service, The Lancet Digital Health, 2019.
L. Fiaschi, Nelson-Piercy, C., Deb, S., King, R., and Tata, L. J., Clinical management of nausea and vomiting in pregnancy and hyperemesis gravidarum across primary and secondary care: a population based study, Bjog, 2019.
F. Nissen, Douglas, I. J., Mullerova, H., Pearce, N., Bloom, C. I., Smeeth, L., and Quint, J. K., Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink), J Asthma Allergy, vol. 12, pp. 7-19, 2019.
A. Schultze, Graham, S., Nordstrom, B. L., Mehmud, F., and Ramagopalan, S. V., Commonly used definitions in real-world studies may underestimate the prevalence of renal disease among nonvalvular atrial fibrillation patients, J Comp Eff Res, 2019.
M. Nowakowska, Zghebi, S. S., Ashcroft, D. M., Buchan, I., Chew-Graham, C., Holt, T., Mallen, C., van Marwijk, H., Peek, N., Perera-Salazar, R., Reeves, D., Rutter, M. K., Weng, S. F., Qureshi, N., Mamas, M. A., and Kontopantelis, E., The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort, BMC Med, vol. 17, p. 145, 2019.
S. J. Sinnott, Smeeth, L., Williamson, E., Perel, P., Nitsch, D., Tomlinson, L. A., and Douglas, I. J., The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data, Pharmacoepidemiol Drug Saf, 2019.
M. E. Saine, Carbonari, D. M., Newcomb, C. W., Gallagher, A. M., Blak, B. T., Roy, J. A., Wood, J., Cardillo, S., Hennessy, S., Strom, B. L., and , Concordance of hospitalizations between Clinical Practice Research Datalink and linked Hospital Episode Statistics among patients treated with oral antidiabetic therapies, Pharmacoepidemiol Drug Saf, 2019.
N. Conrad, Judge, A., Canoy, D., Tran, J., O'Donnell, J., Nazarzadeh, M., Salimi-Khorshidi, G., Hobbs, F. D. R., Cleland, J. G., McMurray, J. J. V., and Rahimi, K., Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients, PLoS Med, vol. 16, p. e1002805, 2019.
S. V. Ramagopalan, Graham, S., Carroll, R., Raluy-Callado, M., Nordstrom, B. L., Donaldson, R., Colby, C., Mehmud, F., and Alikhan, R., Discontinuation and primary care visits in nonvalvular atrial fibrillation patients treated with apixaban or warfarin, J Comp Eff Res, 2019.
G. Nakafero, Grainge, M., Valdes, A., Townsend, N., Mallen, C., Zhang, W., Doherty, M., Mamas, M. A., and Abhishek, A., Do beta-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink, BMJ Open, vol. 9, p. e032050, 2019.
A. Jaggi, Nazir, J., Fatoye, F., Siddiqui, E., Choudhury, N., Argoubi, R., Ali, M., de Ridder, D., and Drake, M. J., Drug utilization patterns and healthcare resource use and costs in patients with neurogenic bladder in the United Kingdom: A retrospective primary care database study, Neurourol Urodyn, 2019.
R. Y. L. Kuo, Ng, M., Prieto-Alhambra, D., and Furniss, D., Dupuytren's disease predicts increased all-cause and cancer-specific mortality: analysis of a large cohort from the UK Clinical Practice Research Datalink, Plast Reconstr Surg, 2019.
M. H. Secrest, Platt, R. W., Dormuth, C. R., Chateau, D., Targownik, L., Nie, R., Doyle, C. M., Dell'Aniello, S., and Filion, K. B., Extreme restriction design as a method for reducing confounding by indication in pharmacoepidemiologic research, Pharmacoepidemiol Drug Saf, 2019.
P. H. Wilding J, Rigney, U., Blak, B. T., Nolan, S. T., Fenici, P., and Medina, J., Glycaemic, weight, and blood pressure changes associated with early versus later treatment intensification with dapagliflozin in United Kingdom primary care patients with type 2 diabetes mellitus, Diabetes Res Clin Pract, p. 107791, 2019.
M. Pikoula, Quint, J. K., Nissen, F., Hemingway, H., Smeeth, L., and Denaxas, S., Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records, BMC Med Inform Decis Mak, vol. 19, p. 86, 2019.
J. T. H. Nielen, Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., and de Vries, F., Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 148, pp. 240-248, 2019.
G. Muduma, Aluvihare, V., Clancy, M., de Nigris, E., Whitlock, C., Landeira, M., and Nazir, J., The Last Year Before Graft Failure Negatively Impacts Economic Outcomes and is Associated With Greater Healthcare Resource Utilization Compared With Previous Years in the United Kingdom: Results of a Retrospective Observational Study, Transplant Direct, vol. 5, p. e443, 2019.
D. Sumilo, Nirantharakumar, K., Willis, B. H., Rudge, G., Martin, J., Gokhale, K., Thayakaran, R., Adderley, N. J., Chandan, J. S., Okoth, K., Hewston, R., Skrybant, M., Deeks, J. J., and Brocklehurst, P., Long-term impact of giving antibiotics before skin incision versus after cord clamping on children born by caesarean section: protocol for a longitudinal study based on UK electronic health records, BMJ Open, vol. 9, p. e033013, 2019.
A. Green, Shaddick, G., Charlton, R., Snowball, J., Nightingale, A., Smith, C., Tillett, W., and McHugh, N., Modifiable risk factors and the development of psoriatic arthritis in people with psoriasis, Br J Dermatol, 2019.
J. M. Ryan, Peterson, M. D., Ryan, N., Smith, K. J., N, E. O. 'Connell, Liverani, S., Anokye, N., Victor, C., and Allen, E., Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy, Dev Med Child Neurol, 2019.
R. Persson, Lee, S., Yood, M. U., Wagner, M., Minton, N., Niemcryk, S., Lindholm, A., Evans, A., and Jick, S., Multi-database study of multiple sclerosis: identification, validation and description of MS patients in two countries, J Neurol, 2019.
A. Henderson, Iwagami, M., Bottomley, C., Tomlinson, L., Mansfield, K., and Nitsch, D., Paediatric acute kidney injury hospital admissions in England 1997–2014: burden and risk factors, Clinical Kidney Journal, 2019.
S. Lay-Flurrie, Mathieu, E., Bankhead, C., Nicholson, B. D., Perera-Salazar, R., Holt, T., Hobbs, F. D. R., and Salisbury, C., Patient consultation rate and clinical and NHS outcomes: a cross-sectional analysis of English primary care data from 2.7 million patients in 238 practices, BMC Health Serv Res, vol. 19, p. 219, 2019.
T. Newlove-Delgado, Hamilton, W., Ford, T. J., Stein, K., and Ukoumunne, O. C., Prescribing for young people with attention deficit hyperactivity disorder in UK primary care: analysis of data from the Clinical Practice Research Datalink, Atten Defic Hyperact Disord, 2019.
[Page last reviewed 5 June 2020]