Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 September 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
M. Nowakowska, Van Staa, T., Molter, A., Ashcroft, D. M., Tsang, J. Y., White, A., Welfare, W., and Palin, V., Antibiotic choice in UK general practice: rates and drivers of potentially inappropriate antibiotic prescribing, J Antimicrob Chemother, 2019.
N. S. Nagra, Robinson, D. E., Douglas, I., Delmestri, A., Dakin, S. G., Snelling, S. J. B., Carr, A. J., and Prieto-Alhambra, D., Antibiotic treatment and flares of rheumatoid arthritis: a self-controlled case series study analysis using CPRD GOLD, Sci Rep, vol. 9, p. 8941, 2019.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink, Ann Rheum Dis, 2019.
G. Nakafero, Grainge, M. J., Myles, P. R., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., and Abhishek, A., Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink, Ann Rheum Dis, 2019.
F. Montastruc, Nie, R., Loo, S., Rej, S., Dell'Aniello, S., Micallef, J., Suissa, S., and Renoux, C., Association of Aripiprazole With the Risk for Psychiatric Hospitalization, Self-harm, or Suicide, JAMA Psychiatry, 2019.
S. Y. Loo, Azoulay, L., Nie, R., Dell'Aniello, S., Yu, O. H. Y., and Renoux, C., Cardiovascular and cerebrovascular safety of testosterone replacement therapy among aging men with low testosterone levels: a cohort study., Am J Med, 2019.
A. V. Gayle, Axson, E. L., Bloom, C. I., Navaratnam, V., and Quint, J. K., Changing causes of death for patients with chronic respiratory disease in England, 2005-2015, Thorax, 2019.
S. Menon, Nightingale, P., and Trudgill, N., Chronic Obstructive Pulmonary Disease and the Risk of Esophagitis, Barrett Esophagus, and Esophageal Adenocarcinoma: A Primary Care Case-Control Study, J Clin Gastroenterol, 2019.
V. Kuan, Denaxas, S., A Izquierdo, G. -, Direk, K., Bhatti, O., Husain, S., Sutaria, S., Hingorani, M., Nitsch, D., Parisinos, C. A., Lumbers, T., Mathur, R., Sofat, R., Casas, J. P., Wong, I. C. K., Hemingway, H., and Hingorani, A. D., A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service, The Lancet Digital Health, 2019.
L. Fiaschi, Nelson-Piercy, C., Deb, S., King, R., and Tata, L. J., Clinical management of nausea and vomiting in pregnancy and hyperemesis gravidarum across primary and secondary care: a population based study, Bjog, 2019.
F. Nissen, Douglas, I. J., Mullerova, H., Pearce, N., Bloom, C. I., Smeeth, L., and Quint, J. K., Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink), J Asthma Allergy, vol. 12, pp. 7-19, 2019.
A. Schultze, Graham, S., Nordstrom, B. L., Mehmud, F., and Ramagopalan, S. V., Commonly used definitions in real-world studies may underestimate the prevalence of renal disease among nonvalvular atrial fibrillation patients, J Comp Eff Res, 2019.
M. Nowakowska, Zghebi, S. S., Ashcroft, D. M., Buchan, I., Chew-Graham, C., Holt, T., Mallen, C., van Marwijk, H., Peek, N., Perera-Salazar, R., Reeves, D., Rutter, M. K., Weng, S. F., Qureshi, N., Mamas, M. A., and Kontopantelis, E., The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort, BMC Med, vol. 17, p. 145, 2019.
S. J. Sinnott, Smeeth, L., Williamson, E., Perel, P., Nitsch, D., Tomlinson, L. A., and Douglas, I. J., The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data, Pharmacoepidemiol Drug Saf, 2019.
M. E. Saine, Carbonari, D. M., Newcomb, C. W., Gallagher, A. M., Blak, B. T., Roy, J. A., Wood, J., Cardillo, S., Hennessy, S., Strom, B. L., and , Concordance of hospitalizations between Clinical Practice Research Datalink and linked Hospital Episode Statistics among patients treated with oral antidiabetic therapies, Pharmacoepidemiol Drug Saf, 2019.
N. Conrad, Judge, A., Canoy, D., Tran, J., O'Donnell, J., Nazarzadeh, M., Salimi-Khorshidi, G., Hobbs, F. D. R., Cleland, J. G., McMurray, J. J. V., and Rahimi, K., Diagnostic tests, drug prescriptions, and follow-up patterns after incident heart failure: A cohort study of 93,000 UK patients, PLoS Med, vol. 16, p. e1002805, 2019.
S. V. Ramagopalan, Graham, S., Carroll, R., Raluy-Callado, M., Nordstrom, B. L., Donaldson, R., Colby, C., Mehmud, F., and Alikhan, R., Discontinuation and primary care visits in nonvalvular atrial fibrillation patients treated with apixaban or warfarin, J Comp Eff Res, 2019.
G. Nakafero, Grainge, M., Valdes, A., Townsend, N., Mallen, C., Zhang, W., Doherty, M., Mamas, M. A., and Abhishek, A., Do beta-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink, BMJ Open, vol. 9, p. e032050, 2019.
A. Jaggi, Nazir, J., Fatoye, F., Siddiqui, E., Choudhury, N., Argoubi, R., Ali, M., de Ridder, D., and Drake, M. J., Drug utilization patterns and healthcare resource use and costs in patients with neurogenic bladder in the United Kingdom: A retrospective primary care database study, Neurourol Urodyn, 2019.
M. H. Secrest, Platt, R. W., Dormuth, C. R., Chateau, D., Targownik, L., Nie, R., Doyle, C. M., Dell'Aniello, S., and Filion, K. B., Extreme restriction design as a method for reducing confounding by indication in pharmacoepidemiologic research, Pharmacoepidemiol Drug Saf, 2019.
P. H. Wilding J, Rigney, U., Blak, B. T., Nolan, S. T., Fenici, P., and Medina, J., Glycaemic, weight, and blood pressure changes associated with early versus later treatment intensification with dapagliflozin in United Kingdom primary care patients with type 2 diabetes mellitus, Diabetes Res Clin Pract, p. 107791, 2019.
M. Pikoula, Quint, J. K., Nissen, F., Hemingway, H., Smeeth, L., and Denaxas, S., Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records, BMC Med Inform Decis Mak, vol. 19, p. 86, 2019.
J. T. H. Nielen, Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., and de Vries, F., Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 148, pp. 240-248, 2019.
G. Muduma, Aluvihare, V., Clancy, M., de Nigris, E., Whitlock, C., Landeira, M., and Nazir, J., The Last Year Before Graft Failure Negatively Impacts Economic Outcomes and is Associated With Greater Healthcare Resource Utilization Compared With Previous Years in the United Kingdom: Results of a Retrospective Observational Study, Transplant Direct, vol. 5, p. e443, 2019.
A. Green, Shaddick, G., Charlton, R., Snowball, J., Nightingale, A., Smith, C., Tillett, W., and McHugh, N., Modifiable risk factors and the development of psoriatic arthritis in people with psoriasis, Br J Dermatol, 2019.
J. M. Ryan, Peterson, M. D., Ryan, N., Smith, K. J., N, E. O. 'Connell, Liverani, S., Anokye, N., Victor, C., and Allen, E., Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy, Dev Med Child Neurol, 2019.
R. Persson, Lee, S., Yood, M. U., Wagner, M., Minton, N., Niemcryk, S., Lindholm, A., Evans, A., and Jick, S., Multi-database study of multiple sclerosis: identification, validation and description of MS patients in two countries, J Neurol, 2019.
A. Henderson, Iwagami, M., Bottomley, C., Tomlinson, L., Mansfield, K., and Nitsch, D., Paediatric acute kidney injury hospital admissions in England 1997–2014: burden and risk factors, Clinical Kidney Journal, 2019.
S. Lay-Flurrie, Mathieu, E., Bankhead, C., Nicholson, B. D., Perera-Salazar, R., Holt, T., Hobbs, F. D. R., and Salisbury, C., Patient consultation rate and clinical and NHS outcomes: a cross-sectional analysis of English primary care data from 2.7 million patients in 238 practices, BMC Health Serv Res, vol. 19, p. 219, 2019.
T. Newlove-Delgado, Hamilton, W., Ford, T. J., Stein, K., and Ukoumunne, O. C., Prescribing for young people with attention deficit hyperactivity disorder in UK primary care: analysis of data from the Clinical Practice Research Datalink, Atten Defic Hyperact Disord, 2019.
T. Newlove-Delgado, Ford, T. J., Hamilton, W., Janssens, A., Stein, K., and Ukoumunne, O. C., Resumption of attention-deficit hyperactivity disorder medication in early adulthood: findings from a UK primary care prescribing study, Eur Child Adolesc Psychiatry, 2019.
C. Rebordosa, Aguado, J., Plana, E., Thomas, S., Frances, A., Lei, A., Garcia-Gil, E., Nuevo, J., Perez-Gutthann, S., and Castellsague, J., Use of aclidinium did not increase the risk of death in a noninterventional cohort study in the Clinical Practice Research Datalink (CPRD), United Kingdom, Respir Med, vol. 152, pp. 37-43, 2019.
2018
I. Tamimi, Nicolau, B., Eimar, H., S. Madathil, A., Kezouh, A., Karp, I., and Tamimi, F., Acetylcholinesterase inhibitors and the risk of osteoporotic fractures: nested case-control study, Osteoporos Int, vol. 29, pp. 849-857, 2018.
K. E. Mansfield, Douglas, I. J., Nitsch, D., Thomas, S. L., Smeeth, L., and Tomlinson, L. A., Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis, Clin Epidemiol, vol. 10, pp. 187-202, 2018.
M. Kerkhof, Tran, T. N., van den Berge, M., Brusselle, G. G., Gopalan, G., Jones, R. C. M., Kocks, J. W. H., Menzies-Gow, A., Nuevo, J., Pavord, I. D., Rastogi, S., and Price, D. B., Association between blood eosinophil count and risk of readmission for patients with asthma: Historical cohort study, PLoS One, vol. 13, p. e0201143, 2018.
M. Iwagami, Caplin, B., Smeeth, L., Tomlinson, L. A., and Nitsch, D., Chronic kidney disease and cause-specific hospitalisation: a matched cohort study using primary and secondary care patient data, Br J Gen Pract, vol. 68, pp. e512-e523, 2018.
L. Li, Neogi, T., and Jick, S., A cohort study of comorbidity in patients with granulomatosis with polyangiitis, Rheumatology (Oxford), vol. 57, pp. 291-299, 2018.
F. Nissen, Morales, D. R., Mullerova, H., Smeeth, L., Douglas, I. J., and Quint, J. K., Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care, Br J Gen Pract, vol. 68, pp. e775-e782, 2018.
G. Moncrieff, Lied-Lied, A., Nelson, G., Holy, C. E., Weinstein, R., Wei, D., and Rowe, S., Cost and effectiveness of prescribing emollient therapy for atopic eczema in UK primary care in children and adults: a large retrospective analysis of the Clinical Practice Research Datalink, BMC Dermatol, vol. 18, p. 9, 2018.
C. Koshiaris, Van den Bruel, A., Oke, J. L., Nicholson, B. D., Shephard, E., Braddick, M., and Hamilton, W., Early detection of multiple myeloma in primary care using blood tests: a case-control study in primary care, Br J Gen Pract, vol. 68, pp. e586-e593, 2018.
C. I. Bloom, Nissen, F., Douglas, I. J., Smeeth, L., Cullinan, P., and Quint, J. K., Exacerbation risk and characterisation of the UK's asthma population from infants to old age, Thorax, vol. 73, pp. 313-320, 2018.
C. I. Alatorre, Hoogwerf, B. J., Deeg, M. A., Nelson, D. R., Hunter, T. M., Ng, W. T., and Rekhter, M. D., Factors associated with stroke, myocardial infarction, ischemic heart disease, unstable angina, or mortality in patients from real world clinical practice with newly-diagnosed type 2 diabetes and early glycemic control, Curr Med Res Opin, vol. 34, pp. 337-343, 2018.
C. I. Alatorre, Hoogwerf, B. J., Deeg, M. A., Nelson, D. R., Hunter, T. M., Ng, W. T., and Rekhter, M. D., Factors associated with stroke, myocardial infarction, ischemic heart disease, unstable angina, or mortality in patients from real world clinical practice with newly-diagnosed type 2 diabetes and early glycemic control, Curr Med Res Opin, vol. 34, pp. 337-343, 2018.
M. Iwagami, Tomlinson, L. A., Mansfield, K. E., Douglas, I. J., Smeeth, L., and Nitsch, D., Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study, Br J Clin Pharmacol, vol. 84, pp. 2142-2151, 2018.
C. Conradt, Guo, D., Miclea, A., Nisslein, T., Ismail, C., Chatamra, K., and Andersohn, F., Increased Prevalence of Polyneuropathy in Parkinson's Disease Patients: An Observational Study, J Parkinsons Dis, vol. 8, pp. 141-144, 2018.
U. Koppe, Nitsch, D., Mansfield, K. E., Mathur, R., Bhaskaran, K., Batterham, R. L., Smeeth, L., and Douglas, I. J., Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink, BMJ Open, vol. 8, p. e020371, 2018.
L. Li, Neogi, T., and Jick, S., Mortality in Patients With Giant Cell Arteritis: A Cohort Study in UK Primary Care, Arthritis Care Res (Hoboken), vol. 70, pp. 1251-1256, 2018.
E. Nortoft, Chubb, B., and Borglykke, A., Obesity and healthcare resource utilization: comparative results from the UK and the USA, Obes Sci Pract, vol. 4, pp. 41-45, 2018.
C. W. le Roux, Chubb, B., Nortoft, E., and Borglykke, A., Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD), Obes Sci Pract, vol. 4, pp. 409-416, 2018.
S. A. Julious, Horspool, M. J., Davis, S., Franklin, M., Smithson, W. H., Norman, P., Simpson, R. M., Elphick, H., Bortolami, O., and Cooper, C., Open-label, cluster randomised controlled trial and economic evaluation of a brief letter from a GP on unscheduled medical contacts associated with the start of the school year: the PLEASANT trial, BMJ Open, vol. 8, p. e017367, 2018.
[Page last reviewed 6 September 2019]