Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,300 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 4 September 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

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2019
A. M. Gallagher, Dedman, D., Padmanabhan, S., Leufkens, H. G. M., and de Vries, F., The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations, Pharmacoepidemiol Drug Saf, 2019.
R. Williams, Kothny, W., Serban, C., Lopez-Leon, S., de Vries, F., and Schlienger, R., Association between vildagliptin and risk of angioedema, foot ulcers, skin lesions, hepatic toxicity, and serious infections in patients with type 2 diabetes mellitus: A European multidatabase, noninterventional, postauthorization safety study, Endocrinol Diabetes Metab, vol. 2, p. e00084, 2019.
O. A. Oshagbemi, Franssen, F. M. E., van Kraaij, S., Braeken, D. C. W., Wouters, E. F. M., van der Zee, A. H. Maitlan, Driessen, J. H. M., and de Vries, F., Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD), Copd, pp. 1-8, 2019.
den C. Heijer, Hoebe, C., Driessen, J. H., Wolffs, P., van den Broek, I., Hoenderboom, B., Williams, R., de Vries, F., and Dukers-Muijrers, N., Chlamydia trachomatis and the Risk of Pelvic Inflammatory Disease, Ectopic Pregnancy, and Female Infertility: A Retrospective Cohort Study Among Primary Care Patients, Clinical Infectious Diseases, 2019.
J. T. H. Nielen, Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., and de Vries, F., Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 148, pp. 240-248, 2019.
A. Tran-Duy, Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F., and de Boer, A., Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study, J Intern Med, vol. 285, pp. 205-214, 2019.
2018
O. A. Oshagbemi, Franssen, F. M. E., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., van der Zee, A. H. Maitlan, Burden, A. M., and de Vries, F., Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality, Pharmacoepidemiol Drug Saf, vol. 27, pp. 1191-1199, 2018.
R. Williams, van Staa, T. P., Gallagher, A. M., Hammad, T., Leufkens, H. G. M., and de Vries, F., Cancer recording in patients with and without type 2 diabetes in the Clinical Practice Research Datalink primary care data and linked hospital admission data: a cohort study, BMJ Open, vol. 8, p. e020827, 2018.
R. de Jong, Peeters, P., Burden, A. M., De Bruin, M. L., Haak, H. R., Masclee, A. A. M., de Vries, F., and Janssen-Heijnen, M. L. G., Gastrointestinal cancer incidence in type 2 diabetes mellitus; results from a large population-based cohort study in the UK, Cancer Epidemiol, vol. 54, pp. 104-111, 2018.
R. Y. van der Velde, Wyers, C. E., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., van de Staa, T. P., and Harvey, N. C., Incidence of subsequent fractures in the UK between 1990 and 2012 among individuals 50 years or older, Osteoporos Int, vol. 29, pp. 2469-2475, 2018.
M. Simeonova, de Vries, F., Pouwels, S., Driessen, J. H. M., Leufkens, H. G. M., Cadarette, S. M., and Burden, A. M., Increased risk of all-cause mortality associated with domperidone use in Parkinson's patients: a population-based cohort study in the UK, Br J Clin Pharmacol, vol. 84, pp. 2551-2561, 2018.
L. Scheepers, Burden, A. M., Arts, I. C. W., Spaetgens, B., Souverein, P., de Vries, F., and Boonen, A., Medication adherence among gout patients initiated allopurinol: a retrospective cohort study in the Clinical Practice Research Datalink (CPRD), Rheumatology (Oxford), vol. 57, pp. 1641-1650, 2018.
H. J. I. De Jong, Tervaert, J. W. Cohen, Lalmohamed, A., de Vries, F., Vandebriel, R. J., Van Loveren, H., Klungel, O. H., and van Staa, T. P., Pattern of risks of rheumatoid arthritis among patients using statins: A cohort study with the clinical practice research datalink, PLoS One, vol. 13, p. e0193297, 2018.
J. van Dalem, Brouwers, M., Stehouwer, C. D. A., Krings, A., Klungel, O. H., Driessen, J. H. M., de Vries, F., and Burden, A. M., Risk of a first-ever acute myocardial infarction and all-cause mortality with sulphonylurea treatment: A population-based cohort study, Diabetes Obes Metab, vol. 20, pp. 1056-1060, 2018.
O. A. Oshagbemi, Keene, S. J., Driessen, J. H. M., Jordan, R., Wouters, E. F. M., de Boer, A., de Vries, F., and Franssen, F. M. E., Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013, Respir Med, vol. 144, pp. 1-6, 2018.
A. Keyany, Nielen, J. T. H., Souverein, P. C., de Vries, F., and van den Bemt, B., Use of parenteral glucocorticoids and the risk of new onset type 2 diabetes mellitus: A case-control study, Diabetes Res Clin Pract, vol. 139, pp. 100-106, 2018.
A. Tran-Duy, Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F., and de Boer, A., Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study, J Intern Med, 2018.
2017
A. But, De Bruin, M. L., Bazelier, M. T., Hjellvik, V., Andersen, M., Auvinen, A., Starup-Linde, J., Schmidt, M. K., Furu, K., de Vries, F., Karlstad, O., Ekstrom, N., and Haukka, J., Cancer risk among insulin users: comparing analogues with human insulin in the CARING five-country cohort study, Diabetologia, vol. 60, pp. 1691-1703, 2017.
R. Williams, de Vries, F., Kothny, W., Serban, C., Lopez-Leon, S., Chu, C., and Schlienger, R., Cardiovascular safety of vildagliptin in patients with type 2 diabetes: A European multi-database, non-interventional post-authorization safety study, Diabetes Obes Metab, vol. 19, pp. 1473-1478, 2017.
C. Klop, van Staa, T. P., Cooper, C., Harvey, N. C., and de Vries, F., The epidemiology of mortality after fracture in England: variation by age, sex, time, geographic location, and ethnicity, Osteoporos Int, vol. 28, pp. 161-168, 2017.
J. H. Driessen, van den Bergh, J. P., van Onzenoort, H. A., Henry, R. M., Leufkens, H. G., and de Vries, F., Long-term use of dipeptidyl peptidase-4 inhibitors and risk of fracture: A retrospective population-based cohort study, Diabetes Obes Metab, vol. 19, pp. 421-428, 2017.
H. J. I. De Jong, van Staa, T. P., Lalmohamed, A., de Vries, F., Vandebriel, R. J., Van Loveren, H., Klungel, O. H., and Tervaert, J. W. Cohen, Pattern of risks of systemic lupus erythematosus among statin users: a population-based cohort study, Ann Rheum Dis, vol. 76, pp. 1723-1730, 2017.
D. C. Braeken, Rohde, G. G., Franssen, F. M., Driessen, J. H., van Staa, T. P., Souverein, P. C., Wouters, E. F., and de Vries, F., Risk of community-acquired pneumonia in chronic obstructive pulmonary disease stratified by smoking status: a population-based cohort study in the United Kingdom, Int J Chron Obstruct Pulmon Dis, vol. 12, pp. 2425-2432, 2017.
B. Spaetgens, de Vries, F., Driessen, J. H. M., Leufkens, H. G., Souverein, P. C., Boonen, A., van der Meer, J. W. M., and Joosten, L. A. B., Risk of infections in patients with gout: a population-based cohort study, Sci Rep, vol. 7, p. 1429, 2017.
E. M. Gieling, van den Ham, H. A., van Onzenoort, H., Bos, J., Kramers, C., de Boer, A., de Vries, F., and Burden, A. M., Risk of major bleeding and stroke associated with the use of vitamin K antagonists, nonvitamin K antagonist oral anticoagulants and aspirin in patients with atrial fibrillation: a cohort study, Br J Clin Pharmacol, vol. 83, pp. 1844-1859, 2017.
L. M. Stolk, de Vries, F., Ebbelaar, C., de Boer, A., Schalekamp, T., Souverein, P., A. Cate-Hoek, T., and Burden, A. M., Risk of myocardial infarction in patients with atrial fibrillation using vitamin K antagonists, aspirin or direct acting oral anticoagulants, Br J Clin Pharmacol, vol. 83, pp. 1835-1843, 2017.
O. A. Oshagbemi, Burden, A. M., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., Driessen, J. H. M., van der Zee, A. H. Maitlan, de Vries, F., and Franssen, F. M. E., Stability of Blood Eosinophils in Patients with Chronic Obstructive Pulmonary Disease and in Control Subjects, and the Impact of Sex, Age, Smoking, and Baseline Counts, Am J Respir Crit Care Med, vol. 195, pp. 1402-1404, 2017.
R. Y. van der Velde, Wyers, C. E., Teesselink, E., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., Harvey, N. C., and van Staa, T. P., Trends in oral anti-osteoporosis drug prescription in the United Kingdom between 1990 and 2012: Variation by age, sex, geographic location and ethnicity, Bone, vol. 94, pp. 50-55, 2017.
L. M. Knapen, de Jong, R. G., Driessen, J. H., Keulemans, Y. C., van Erp, N. P., De Bruin, M. L., Leufkens, H. G., Croes, S., and de Vries, F., Use of incretin agents and risk of acute and chronic pancreatitis: A population-based cohort study, Diabetes Obes Metab, vol. 19, pp. 401-411, 2017.
2016
I. Essers, Stolwijk, C., Boonen, A., De Bruin, M. L., Bazelier, M. T., de Vries, F., and van Tubergen, A., Ankylosing spondylitis and risk of ischaemic heart disease: a population-based cohort study, Ann Rheum Dis, vol. 75, pp. 203-9, 2016.
R. G. de Jong, Gallagher, A. M., Herrett, E., Masclee, A. A., Janssen-Heijnen, M. L., and de Vries, F., Comparability of the age and sex distribution of the UK Clinical Practice Research Datalink and the total Dutch population, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1460-1464, 2016.
E. M. Curtis, van der Velde, R., Moon, R. J., van den Bergh, J. P., Geusens, P., de Vries, F., van Staa, T. P., Cooper, C., and Harvey, N. C., Epidemiology of fractures in the United Kingdom 1988-2012: Variation with age, sex, geography, ethnicity and socioeconomic status, Bone, vol. 87, pp. 19-26, 2016.
R. J. Moon, Harvey, N. C., Curtis, E. M., de Vries, F., Van Staa, T., and Cooper, C., Ethnic and geographic variations in the epidemiology of childhood fractures in the United Kingdom, Bone, vol. 85, pp. 9-14, 2016.
C. Huerta, Abbing-Karahagopian, V., Requena, G., Oliva, B., Alvarez, Y., Gardarsdottir, H., Miret, M., Schneider, C., Gil, M., Souverein, P. C., De Bruin, M. L., Slattery, J., de Groot, M. C., Hesse, U., Rottenkolber, M., Schmiedl, S., Montero, D., Bate, A., Ruigomez, A., Garcia-Rodriguez, L. A., Johansson, S., de Vries, F., Schlienger, R. G., Reynolds, R. F., Klungel, O. H., and de Abajo, F. J., Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project, Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 56-65, 2016.
B. P. Verhaegh, de Vries, F., Masclee, A. A., Keshavarzian, A., de Boer, A., Souverein, P. C., Pierik, M. J., and Jonkers, D. M., High risk of drug-induced microscopic colitis with concomitant use of NSAIDs and proton pump inhibitors, Aliment Pharmacol Ther, vol. 43, pp. 1004-13, 2016.
A. M. Gallagher, Williams, T., Leufkens, H. G., and de Vries, F., The Impact of the Choice of Data Source in Record Linkage Studies Estimating Mortality in Venous Thromboembolism, PLoS One, vol. 11, p. e0148349, 2016.
M. Schuerch, Gasse, C., Robinson, N. J., Alvarez, Y., Walls, R., Mors, O., Christensen, J., Hesse, U., de Groot, M., Schlienger, R., Reynolds, R., Klungel, O., and de Vries, F., Impact of varying outcomes and definitions of suicidality on the associations of antiepileptic drugs and suicidality: comparisons from UK Clinical Practice Research Datalink (CPRD) and Danish national registries (DNR), Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 142-55, 2016.
P. J. Peeters, Bazelier, M. T., Leufkens, H. G., Auvinen, A., van Staa, T. P., de Vries, F., and De Bruin, M. L., Insulin glargine use and breast cancer risk: Associations with cumulative exposure, Acta Oncol, vol. 55, pp. 851-8, 2016.
C. Klop, de Vries, F., Bijlsma, J. W., Leufkens, H. G., and Welsing, P. M., Predicting the 10-year risk of hip and major osteoporotic fracture in rheumatoid arthritis and in the general population: an independent validation and update of UK FRAX without bone mineral density, Ann Rheum Dis, vol. 75, pp. 2095-2100, 2016.
J. van Dalem, Brouwers, M. C., Stehouwer, C. D., Krings, A., Leufkens, H. G., Driessen, J. H., de Vries, F., and Burden, A. M., Risk of hypoglycaemia in users of sulphonylureas compared with metformin in relation to renal function and sulphonylurea metabolite group: population based cohort study, Bmj, vol. 354, p. i3625, 2016.
J. T. Nielen, Dagnelie, P. C., Emans, P. J., Veldhorst-Janssen, N., Lalmohamed, A., van Staa, T. P., Boonen, A. E., van den Bemt, B. J., and de Vries, F., Safety and efficacy of new oral anticoagulants and low-molecular-weight heparins compared with aspirin in patients undergoing total knee and hip replacements, Pharmacoepidemiol Drug Saf, vol. 25, pp. 1245-1252, 2016.
R. Y. van der Velde, Wyers, C. E., Curtis, E. M., Geusens, P., van den Bergh, J. P. W., de Vries, F., Cooper, C., van Staa, T. P., and Harvey, N. C., Secular trends in fracture incidence in the UK between 1990 and 2012, Osteoporos Int, vol. 27, pp. 3197-3206, 2016.
J. T. Nielen, Emans, P. J., Dagnelie, P. C., Boonen, A., Lalmohamed, A., de Boer, A., van den Bemt, B. J., and de Vries, F., Severity of Diabetes Mellitus and Total Hip or Knee Replacement: A Population-Based Case-Control Study, Medicine (Baltimore), vol. 95, p. e3739, 2016.
L. M. Knapen, van Dalem, J., Keulemans, Y. C., van Erp, N. P., Bazelier, M. T., De Bruin, M. L., Leufkens, H. G., Croes, S., Neef, C., de Vries, F., and Driessen, J. H., Use of incretin agents and risk of pancreatic cancer: a population-based cohort study, Diabetes Obes Metab, vol. 18, pp. 258-65, 2016.
J. T. Nielen, de Vries, F., Dagnelie, P. C., van den Bemt, B. J., Emans, P. J., Lalmohamed, A., de Boer, A., and Boonen, A., Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case-control study, Br J Clin Pharmacol, vol. 81, pp. 370-8, 2016.
2015
C. Klop, Gibson-Smith, D., Elders, P. J., Welsing, P. M., Leufkens, H. G., Harvey, N. C., Bijlsma, J. W., van Staa, T. P., and de Vries, F., Anti-osteoporosis drug prescribing after hip fracture in the UK: 2000-2010, Osteoporos Int, vol. 26, pp. 1919-28, 2015.
J. H. Driessen, Henry, R. M., van Onzenoort, H. A., Lalmohamed, A., Burden, A. M., Prieto-Alhambra, D., Neef, C., Leufkens, H. G., and de Vries, F., Bone fracture risk is not associated with the use of glucagon-like peptide-1 receptor agonists: a population-based cohort analysis, Calcif Tissue Int, vol. 97, pp. 104-12, 2015.
C. Stolwijk, Essers, I., van Tubergen, A., Boonen, A., Bazelier, M. T., De Bruin, M. L., and de Vries, F., The epidemiology of extra-articular manifestations in ankylosing spondylitis: a population-based matched cohort study, Ann Rheum Dis, vol. 74, pp. 1373-8, 2015.
J. T. Nielen, van den Bemt, B. J., Boonen, A., Dagnelie, P. C., Emans, P. J., Veldhorst, N., Lalmohamed, A., van Staa, T. P., and de Vries, F., Identification of antithrombotic drugs related to total joint replacement using anonymised free-text notes: a search strategy in the Clinical Practice Research Datalink, BMJ Open, vol. 5, p. e009017, 2015.
J. M. Wijnands, van Durme, C. M., Driessen, J. H., Boonen, A., Klop, C., Leufkens, B., Cooper, C., Stehouwer, C. D., and de Vries, F., Individuals With Type 2 Diabetes Mellitus Are at an Increased Risk of Gout But This Is Not Due to Diabetes: A Population-Based Cohort Study, Medicine (Baltimore), vol. 94, p. e1358, 2015.
[Page last reviewed 6 September 2019]