Clinical Practice Research Datalink

Clinical Practice Research Datalink (CPRD) is a real-world research service supporting retrospective and prospective public health and clinical studies. CPRD is jointly sponsored by the Medicines and Healthcare products Regulatory Agency and the National Institute for Health Research (NIHR), as part of the Department of Health and Social Care.

CPRD collects de-identified patient data from a network of GP practices across the UK. Primary care data are linked to a range of other health related data to provide a longitudinal, representative UK population health dataset. The data encompass 50 million patients, including 15 million currently registered patients.

For more than 30 years, research using CPRD data and services has informed clinical guidance and best practice, resulting in over 2,500 peer-reviewed publications investigating drug safety, use of medicines, effectiveness of health policy, health care delivery and disease risk factors.

In response to the coronavirus outbreak, CPRD is expediting processing of protocols relating to COVID-19 research. To ascertain whether your protocol is eligible for rapid review please email isac@cprd.com before you submit your application and include a clear impact statement in terms of public health, safety or policy. To understand how the current situation may impact on data processing and access requests see here.

To help coordinate activities and avoid duplication of research effort, see information on COVID-19 studies underwayFind out more about the COVID-19 data included in the CPRD primary care databases.

Longitudinal primary care records

Linkage to health datasets

50 million patients

UK network of GP practices

15 million recruitment pool

Retrospective and prospective