Approved studies using CPRD Data

Applications to access CPRD data for observational research are reviewed by the Independent Scientific Advisory Committee (ISAC). Approval by ISAC is required for researchers to carry out their proposed studies.

A summary of all ISAC-approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study.

The table below includes all ISAC-approved protocols submitted to CPRD from 1st July 2015. Searches can be carried out using applicant names, approval date or by using key words within the protocol title. Protocols below are listed in order of date of approval.

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

 

ISAC Approval Date Title
01/11/2019 Patient and clinical characteristics of new users to single or multiple inhaled triple therapy in patients with COPD in the UK
27/09/2019 Patient pathway and therapeutic inertia in newly diagnosed T2DM patients with multimorbidity
05/09/2019 Evaluation of the survival, treatment pathways and liver disease outcomes of patients with liver disease and their progression to cirrhosis and hepatic encephalopathy: a non-interventional study using primary and secondary healthcare data from the UK
07/08/2019 The long-term impact of vaginal surgical mesh devices in UK primary care: a cohort study in the CPRD
31/07/2019 Use of the STarT Back Screening Tool for Low Back Pain in Primary Care
26/07/2019 5-Alpha Reductase Inhibitors and the Risk of Anaemia
26/07/2019 Trends in Prescription of Antihypertensive Medications in UK Primary Care Practices, 1988-2018
26/07/2019 Suspected cancer symptoms and blood test results in primary care before a diagnosis of lung cancer: a case-control study
24/07/2019 Comparative effectiveness of gliclazide MR and sitagliptin as second line treatment after metformin monotherapy in uncontrolled type 2 diabetes patients using the UK Clinical Practice Research Datalink (CPRD) database
23/07/2019 Real world data on utilisation and safety of Movicol paediatric plain among children <2 years
18/07/2019 Prevalence of established cardiovascular disease in patients with type 2 diabetes mellitus in the UK
11/07/2019 Investigating capacity for NICE guidance on recognition and referral for suspected cancer
10/07/2019 Association of serum bilirubin level with renal outcomes in patients with type 2 diabetes and patients with essential hypertension
04/07/2019 Variation in healthcare utilisation across primary and secondary care for patients with type 1 and type 2 diabetes
28/06/2019 Trends in Acid Suppressant Drug Prescriptions in Primary Care in the United Kingdom
19/06/2019 Treatment cut-offs for blood pressure lowering and lipid lowering treatment: a cohort study in UK primary care
12/06/2019 Potentially unintended discontinuation of medication following hospitalisation: a retrospective cohort study
12/06/2019 Treatment patterns among new users of maintenance asthma medications in the United Kingdom
06/06/2019 An observational, retrospective, matched case-control study to assess the effectiveness of Priorix vaccine in children born after 2004 in the United Kingdom (UK)
06/06/2019 Trends in diabetes-related complications and cause of death in patients with diabetes in England