Approved studies using CPRD Data

Applications to access CPRD data for observational research are reviewed by the Independent Scientific Advisory Committee (ISAC). Approval by ISAC is required for researchers to carry out their proposed studies.

A summary of all ISAC-approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study.

The table below includes all ISAC-approved protocols submitted to CPRD from 1st July 2015. Searches can be carried out using applicant names, approval date or by using key words within the protocol title. Protocols below are listed in order of date of approval.

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

 

ISAC Approval Date Title
19/12/2018 Testing a data-based definition of severity in atopic dermatitis in a linked primary and secondary care dataset in England: Implications on clinical outcomes and healthcare resource use
19/12/2018 The Health Economic Burden of Atopic Dermatitis and Associated Dermatologic Conditions: A Study of Cow's Milk Allergy (CMA) in patients > 5 years of age in the Primary and Secondary Care Pathways
21/12/2018 The pattern of incident fractures in patients with diabetes mellitus compared to matched controls
02/01/2019 An epidemiological study to compare adverse events associated with different formulations of latanoprost
10/01/2019 Understanding the Relationship between Multimorbidity in Later Life, Use of Health Services and Costs of Health Care (MuSeCol)
10/01/2019 Guideline discordant diagnostic care: when do primary care referrals not reflect guidelines for suspected cancer?
10/01/2019 Mapping the opportunities for earlier diagnosis and characterising the management costs of psoriasis and impact of key co-morbidities
17/01/2019 Identifying predictors of drug treatment response in bipolar disorder
17/01/2019 Dose adjustment or discontinuous use of direct oral anticoagulants related to the concurrent use of potential interacting drugs
17/01/2019 Effectiveness of long acting muscarinic-antagonist- (LAMA) as an add-on to inhaled corticosteroids / long acting beta-agonists (LABA) in smoking asthmatics
22/01/2019 Life-Limiting Conditions: the health of children and their Mothers
24/01/2019 C-reactive protein as a biomarker of response to inhaled corticosteroids in COPD
25/01/2019 Inflammatory Skin Diseases and the Risk of Chronic Kidney Disease - Cross-sectional and Cohort Studies
29/01/2019 Fractured wrist; predictors of poor long-term clinical and socioeconomic outcomes (The FILTER Study)
29/01/2019 Incidence of major adverse cardiovascular and cerebrovascular events (MACE) in patients with psoriasis, psoriatic arthritis and ankylosing spondylitis: a retrospective analysis of a United Kingdom database
01/02/2019 Characterising end of life health care expenditure
05/02/2019 The association of cancer and autism spectrum condition in a UK population
08/02/2019 Treatment pathways to severe asthma and health care resource utilisation in the UK
08/02/2019 Risks of antidepressants on cardiovascular mortality and morbidity, suicidality, falls and fractures in people with obesity and depression in primary care
08/02/2019 Investigating the extent to which exposure to varicella boosts Varicella zoster virus-immunity: a self-controlled case-series, 1997-2018