Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page


Date of Approval Title
01/08/2016 Use and costs of primary care consultations and prescription medications in relation to body mass index in middle-aged UK women
01/08/2016 Comparison of Health Economic Outcomes for Patients with Asthma who switch from Seretide to flutiform or Fostair using the CPRD-HES Linked Database
01/08/2016 Can Novel Integrated Risk Schemes Change Treatment Decisions and Improve Health Outcomes in the Year after a Diagnosis of Atrial Fibrillation? An Individual-Based Simulation
02/08/2016 Obstructive airway disease phenotype discovery using cluster analysis techniques in CPRD
02/08/2016 Comparison of information on diagnosis of musculoskeletal outcomes in the Million Women Study cohort and CPRD-GOLD: a record linkage study
02/08/2016 Metabolic syndrome and risk of meningioma - population-based case-control analysis
15/08/2016 Comprehensive ascertainment of bleeding in patients prescribed different combinations of dual antiplatelet therapy (DAPT) and triple therapy (TT, DAPT plus an anticoagulant) after coronary interventions in the UK (The ADAPTT Study).
15/08/2016 Proton pump inhibitors and kidney disease: a self-controlled case series and cohort study
16/08/2016 Validating the CirCom Score in the English CPRD population
16/08/2016 Cohort study on the uptake of pharmacological treatments to prevent cardiovascular diseases in UK cancer survivors versus general population from 2005-2013.
16/08/2016 External validation of risk scores for dementia in the CPRD population
17/08/2016 Residual Risk and Burden of Cardiovascular Diseases in the United Kingdom
17/08/2016 Reproductive risk factors for prostate cancer incidence, mortality and survival
22/08/2016 Weight loss as a predictor of cancer and serious disease in primary care.
22/08/2016 A feasibility study to develop within primary care IT systems a computer program for flagging patients with risk factors for HIV who would benefit from having an HIV test
23/08/2016 Domperidone for insufficient lactation: a drug utilization study with interrupted time-series analysis
23/08/2016 Hormone Therapy in Relation to Risks of Second Cancers and Mortality Among Women and Men
24/08/2016 Body mass index and cause-specific mortality - population-based cohort study using record linkage
24/08/2016 The role of social determinants in vaccine uptake and burden of vaccine preventable diseases
12/09/2016 Prescription trends among drug pairs with a known drug-drug interaction in primary care