Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page


Date of Approval Title
26/06/2020 A cohort study examining access to NHS weight management services using routine data from primary and secondary care
23/06/2020 Risk of major adverse cardiac events in atherosclerotic cardiovascular disease, atherosclerotic cardiovascular disease - risk equivalent and familial hypercholesterolaemia patients with elevated low-density lipoprotein cholesterol
23/06/2020 The prevalent new-user design for cohort studies with no active comparator: The example of statins and cancer
23/06/2020 Examining methodology to identify patterns of consulting in primary care for different groups of patients before a diagnosis of cancer: a matched retrospective cohort study
22/06/2020 Fluoroquinolones and the risk of retinal detachment, uveitis, peripheral neuropathy, and hospitalisation with aortic aneurysm or dissection
18/06/2020 Investigation into changes in Prostate Specific Antigen (PSA) testing rate over time: A join point analysis
18/06/2020 Risk factors and outcomes of COVID-19 in individuals with Down syndrome
17/06/2020 Impact of suboptimal temperature exposure on health at all stages of care
17/06/2020 International trends in dual antiplatelet therapy among PCI-treated STEMI and NSTEMI patients: Pendant study in the UK
17/06/2020 Area, maternal and child determinants of MMR uptake
16/06/2020 The Burden of Illness of Human Health Outcomes Arising from Human-Animal Interactions
16/06/2020 Evaluating the health impact of familial hypercholesterolaemia in primary care patients compared with an intensively managed specialist disease registry
12/06/2020 Assessing factors associated with the COVID-19 risk in people with asthma
09/06/2020 Risk factors for and long-term outcomes in people with covid-19 admitted to hospital in England
09/06/2020 Exploring the role of electronic Frailty Index (eFI) using routine primary care electronic health care records data to predict hospitalization and mortality in older patients with type 2 diabetes
09/06/2020 Investigating the impact of frailty on the risks and benefits of hip and knee replacement surgery
09/06/2020 Retrospective cohort study to estimate age-stratified cardio-respiratory and exacerbations of diabetes outcome rates to support influenza vaccine rVE study planning in Europe
08/06/2020 Developing the optimum strategy for coeliac disease case finding in adults and children
08/06/2020 A comparison of the prevalence of electronic health record diagnoses of herpes zoster and simplex with self-reported prevalence from national population surveys and cohorts from the United Kingdom
08/06/2020 Exacerbations and their Outcomes (EXACOS): Understanding the pathway to exacerbations of COPD and the association between frequency of exacerbations and risk of clinical and health-care utilization outcomes