Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page


Date of Approval Title
05/05/2020 Antimicrobial stewardship during the COVID-19 epidemic. Cohort study
05/05/2020 Consultations for non-specific symptoms commonly reported with COVID-19 and other acute respiratory infections in the Clinical Practice Research Datalink: long term trends and patient characteristics
05/05/2020 The association between amoxicillin exposure in infancy and the development of asthma in later childhood in the UK: A retrospective cohort study using Clinical Practice Research Datalink
30/04/2020 Drug Utilisation Study extension (DUS ext.) of valproate and related substances, in Europe, using databases
30/04/2020 Exploring the relationship between NSAID prescribing and complications in patients with common infections
28/04/2020 Utilisation and safety of Glycopyrronium Bromide (GPB) oral solution for the treatment of sialorrhoea in children <18 years in the UK
28/04/2020 A retrospective cohort study to describe primary and secondary healthcare use and associated costs, and patterns of investigation and treatment in adult patients with chronic cough in the United Kingdom
28/04/2020 Assessing the long-term impact of infant rotavirus vaccination on the age-related risk of acute gastroenteritis and heterologous effects of vaccination in children: a cohort study
27/04/2020 Underlying conditions in coronavirus (COVID-19) infection: definition, prevalence, mortality and understanding risk
22/04/2020 Resource burden and treatment pathway for Type 2 Diabetic patients with Diabetic Kidney Disease in England: A study utilising primary and secondary care datasets
22/04/2020 Proton Pump Inhibitors and Gastric Cancer Incidence: A Population-based Cohort Study
20/04/2020 Examining the clinical and economic outcomes associated with cancer survivorship
20/04/2020 Psychological distress associated with the current COVID-19 outbreak: evidence from electronic health records
20/04/2020 COVID-19 related risks in cancer survivors: a matched cohort study using linked UK electronic health records data
20/04/2020 Investigating early diagnoses of patients with ankylosing spondylitis using machine learning: a predictive modelling study
20/04/2020 Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) Study
16/04/2020 COVID-19 and drugs acting on the renin angiotensin system
16/04/2020 Quantifying Bias in Epidemiological Studies on the Association Between Acetaminophen and Cancer 2
15/04/2020 Cardiovascular safety of SGLT2 inhibitors in type 2 diabetes: The effect of obesity
15/04/2020 Descriptive analysis of primary care consultations in England from 2000 to 2018