Approved studies using CPRD Data

Access to CPRD data, including UK Primary Care Data, and linked data such as Hospital Episode Statistics, is subject to protocol approval via CPRD’s Research Data Governance (RDG) Process. Independent scientific and patient advice is provided by Expert Review Committees (ERCs) and the Central Advisory Committee (CAC). 

A summary of all approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study. COVID-19 research protocols are being fast-tracked and all approved summaries are published within 72 hours to ensure transparency and to help avoid unnecessary duplication. 

Protocols below are listed in order of date of approval. Please click on the study title for more details. 

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page


Date of Approval Title
07/05/2021 Incidence and prevalence of mental illness in pregnancy and the first five years after giving birth: a retrospective cohort study using electronic primary care data
06/05/2021 Impact of underlying diseases, diagnostic processes and treatment on heart failure disease trajectory using international data
06/05/2021 The risk of acute infection in patients with newly diagnosed depression: a cohort study
05/05/2021 Evaluating ethnic differences in blood markers of cancer in primary care
04/05/2021 The Prescribing of Analgesia and Predictors of Long-Term Analgesia Prescriptions in Patients with Inflammatory Arthritis: An Observational Study using the Clinical Practice Research Datalink.
30/04/2021 Completeness and representativeness of small area socioeconomic data linked with the UK Clinical Practice Research Datalink (CPRD)
29/04/2021 Multimorbidity and lipid response to statins: a cohort study
28/04/2021 Glycaemic control across ethnicity of insulin-naive type 2 diabetes patients residing in England when initiating Biphasic insulin aspart 30-70 (BIAsp 30)
28/04/2021 Epidemiology and burden of Illness of familial hypercholesterolaemia and hypercholesterolaemia in combination with atherosclerotic cardiovascular disease or atherosclerotic cardiovascular disease risk equivalence.
27/04/2021 Long COVID in non-hospitalised individuals: symptoms, risk factors and syndromes
27/04/2021 The safety of proton pump inhibitors in children with gastroesophageal reflux disease
27/04/2021 Burden of polycystic ovary syndrome during pregnancy and offspring outcomes
27/04/2021 Long COVID in non-hospitalised individuals: symptoms, risk factors and syndromes
23/04/2021 A comparison of clinical outcomes, health care resource utilisation and costs for patients with chronic lower limb ulcers including diabetic and venous ulcers when prescribed Prontosan (including solution and gel) and saline solution in England
23/04/2021 Risk of fractures in cancer survivors in the United Kingdom: a population-based matched cohort study using linked electronic health records databases
22/04/2021 Prediction of which patients with venous thromboembolism may benefit from an extended anticoagulation 3 months post diagnosis
15/04/2021 Characterizing the changing morbidity and cause-specific mortality burden of the obesity epidemic in England and the UK
15/04/2021 Propensity to order diagnostic blood tests in general practices
15/04/2021 Completeness and representativeness of ethnicity data in the UK Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES)
15/04/2021 Preventing stroke, premature death and cognitive decline in a broader community of patients with atrial fibrillation using healthcare data for pragmatic research: A randomised controlled trial (DaRe2THINK)