Approved studies using CPRD Data

Applications to access CPRD data for observational research are reviewed by the Independent Scientific Advisory Committee (ISAC). Approval by ISAC is required for researchers to carry out their proposed studies.

A summary of all ISAC-approved protocols, including a lay and technical summary of the proposed research, is published three months after researchers have access to the data to begin their study.

The table below includes all ISAC-approved protocols submitted to CPRD from 1st July 2015. Searches can be carried out using applicant names, approval date or by using key words within the protocol title. Protocols below are listed in order of date of approval.

Peer-reviewed publications from research using CPRD data will be listed on our bibliography page

 

ISAC Approval Date Title
22/08/2018 Prediction of anticoagulation control and associated health economic outcomes in patients with atrial fibrillation (AF) managed on warfarin
22/08/2018 Assessing the Burden of Allergy Management in England
14/08/2018 Do systemic antibiotics affect the effectiveness of chemotherapy for malignant cancers? - A cohort study based on CPRD and Cancer Registry data
09/08/2018 An assessment of CPRD Aurum data quality
08/08/2018 Fractures in people with intellectual disabilities: comparison with the general population and development of a fracture risk calculator specific to these patients
07/08/2018 Relationship between Body Mass Index (BMI) trajectory and the risk of cardiovascular disease and diabetes among overweight and obese people: A UK Primary Care-based cohort study
07/08/2018 M.A.P.P.E.D. IMproving the Accuracy of Psychosis PrEDiction using primary-care consultation data
01/08/2018 Asthma and Type 2 Co-morbidities
01/08/2018 Defining patient groups at short-term high risk of fracture and evaluating current practice of osteoporosis treatment and rate of different fractures and cardiovascular events in these patient groups
01/08/2018 Impact of subsequent major adverse cardiovascular events on mortality in a post-myocardial infarction population: a retrospective UK database analysis
01/08/2018 A study on the epidemiology of tinnitus in the United Kingdom
27/07/2018 Do NHS Health Checks improve patient's Diabetic Healthcare outcomes? A population-based study using the CPRD
27/07/2018 A study of cardiovscular mortality and morbidity of patients with adrenal insufficiency
24/07/2018 Understanding the impact of the routine use of anti-diabetic (PPAR gamma)/anti-hyperlipidaemic (PPAR alpha) medication on risk of brain tumours and case fatality
24/07/2018 Determining the frequency of abnormal hepatic fibrosis measures and liver cirrhosis/decompensation in UK primary care
23/07/2018 Long term impact of giving antibiotics before skin incision versus after cord clamping on children born by caesarean section: longitudinal study based on UK electronic health records
23/07/2018 Evaluating effect modification using propensity score matching and disease risk score methods: an empirical study
20/07/2018 Dipeptidyl peptidase-4 inhibitors and the risk of bullous pemphigoid among patients with type 2 diabetes
20/07/2018 Serum cholesterol trajectories in the years prior to lymphoma diagnosis
20/07/2018 Using electronic health records to assess effectiveness of national policy in dementia recognition in the UK