Evaluating the utility of the CPRD GOLD-HTI linkage: anticoagulant prescribing at the GP practice compared to hospital dispensed medication at discharge date

Date of ISAC Approval: 
Lay Summary: 
At discharge from hospital, patients are usually only supplied with a limited amount of medication. Often this is followed up by the GP issuing further prescriptions. This study aims to look at patients who are dispensed blood-thinning drugs at the point of discharge from hospital to see if the linkage between hospital pharmacy information and primary care data makes it possible to look at whether these drugs are continued at the GP. This is a feasibility study evaluating the linkage between hospital pharmacy data and GP prescribing.
Technical Summary: 
This study aims to demonstrate the utility of the linkage between CPRD primary care data (GOLD) and the HTI which links hospital dispensing information, events in hospital and the primary care data. To do this, anticoagulants (novel oral anticoagulants (NOACs) heparin and warfarin) have been chosen as an example medication that may be initiated in hospital and continued by the GP. The aim is to see if we can follow patients from one setting (hospital) to the next (primary care).
Health Outcomes to be Measured: 
Anticoagulant prescribing at the GP practice

Ms Arlene Gallagher - Chief Investigator - CPRD
Mr Adam Collier - Collaborator - IQVIA - UK
Ms Hassy Dattani - Collaborator - EPIC UK
Ms Rachel Tham - Collaborator - IQVIA - UK
Dr Tim Williams - Collaborator - CPRD