Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,700 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 6 April 2021) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


 (PDF, 5MB, 226 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website



Export 9 results:
Author Title [ Type(Asc)] Year
Filters: Author is Klungel, O.  [Clear All Filters]
Journal Article
N. C. C. Werkman, Nielen, J. T. H., van den Bergh, J. P. W., Ejskjaer, N., Røikjer, J., Schaper, N. C., Rossi, B., Klungel, O., Vestergaard, P., de Vries, F., and Driessen, J. H. M., Use of Sodium-Glucose Co-Transporter-2-Inhibitors (SGLT2-Is) and Risk of Lower Limb Amputation, Curr Drug Saf, 2020.
R. Brauer, Ruigomez, A., Klungel, O., Reynolds, R., M. Tepie, F., Smeeth, L., and Douglas, I., The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies, Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 39-46, 2016.
R. Brauer, Ruigomez, A., Downey, G., Bate, A., Rodriguez, L. A. Garcia, Huerta, C., Gil, M., de Abajo, F., Requena, G., Alvarez, Y., Slattery, J., de Groot, M., Souverein, P., Hesse, U., Rottenkolber, M., Schmiedl, S., de Vries, F., Tepie, M. F., Schlienger, R., Smeeth, L., Douglas, I., Reynolds, R., and Klungel, O., Prevalence of antibiotic use: a comparison across various European health care data sources, Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 11-20, 2016.
A. Afonso, Schmiedl, S., Becker, C., Tcherny-Lessenot, S., Primatesta, P., Plana, E., Souverein, P., Wang, Y., Korevaar, J. C., Hasford, J., Reynolds, R., de Groot, M. C., Schlienger, R., Klungel, O., and Rottenkolber, M., A methodological comparison of two European primary care databases and replication in a US claims database: inhaled long-acting beta-2-agonists and the risk of acute myocardial infarction, Eur J Clin Pharmacol, vol. 72, pp. 1105-16, 2016.
L. Ibanez, Sabate, M., Vidal, X., Ballarin, E., Rottenkolber, M., Schmiedl, S., Heeke, A., Huerta, C., E. Merino, M., Montero, D., Leon-Munoz, L. M., Gasse, C., Moore, N., Droz, C., Lassalle, R., Aakjaer, M., Andersen, M., De Bruin, M. L., Groenwold, R., van den Ham, R., Souverein, P., Klungel, O., and Gardarsdottir, H., Incidence of Direct Oral Anticoagulant use in patients with non-valvular atrial fibrillation and characteristics of users in six European countries (2008-2015): A cross-national drug utilization study, Br J Clin Pharmacol, 2019.
M. Schuerch, Gasse, C., Robinson, N. J., Alvarez, Y., Walls, R., Mors, O., Christensen, J., Hesse, U., de Groot, M., Schlienger, R., Reynolds, R., Klungel, O., and de Vries, F., Impact of varying outcomes and definitions of suicidality on the associations of antiepileptic drugs and suicidality: comparisons from UK Clinical Practice Research Datalink (CPRD) and Danish national registries (DNR), Pharmacoepidemiol Drug Saf, vol. 25 Suppl 1, pp. 142-55, 2016.
J. T. H. Nielen, Dagnelie, P. C., Boonen, A., Klungel, O., van den Bemt, B., and de Vries, F., Impact of the definition of osteoarthritis and of the timing of its onset on the association between type 2 diabetes mellitus and osteoarthritis: Clinical Practice Research Datalink, Diabetes Res Clin Pract, vol. 148, pp. 240-248, 2019.
L. Grimaldi-Bensouda, Klungel, O., Kurz, X., de Groot, M. C., Afonso, A. S. Maciel, De Bruin, M. L., Reynolds, R., and Rossignol, M., Calcium channel blockers and cancer: a risk analysis using the UK Clinical Practice Research Datalink (CPRD), BMJ Open, vol. 6, p. e009147, 2016.
A. Ruigomez, Brauer, R., Rodriguez, L. A., Huerta, C., Requena, G., Gil, M., de Abajo, F., Downey, G., Bate, A., Tepie, M. F., de Groot, M., Schlienger, R., Reynolds, R., and Klungel, O., Ascertainment of acute liver injury in two European primary care databases, Eur J Clin Pharmacol, vol. 70, pp. 1227-35, 2014.
[Page last reviewed 6 April 2021]