Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,200 peer-reviewed publications.

The CPRD bibliography is updated on a monthly basis (last updated 5 August 2019) and papers are listed below and in the PDF below.

If you have published papers using CPRD data which are not included in this list, please contact us at so that we can update the bibliography.


(PDF, 3MB, 187 pages)


Export 2296 results:
Author Title Type [ Year(Desc)]
S. S. Jick, Stender, M., and Myers, M. W., Frequency of liver disease in type 2 diabetic patients treated with oral antidiabetic agents, Diabetes Care, vol. 22, pp. 2067-71, 1999.
M. Carter, Moser, K., and Kelly, S., Health of older people: disease prevalence, prescription and referral rates, England and Wales 1996, Health Statistics Quarterly, vol. 4, pp. 9-15, 1999.
M. Lawrence, Jones, L., Lancaster, T., Daly, E., and Banks, E., Hormone replacement therapy: patterns of use studied through British general practice computerized records, Fam Pract, vol. 16, pp. 335-42, 1999.
L. A. Rodriguez and Ruigomez, A., Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study, Bmj, vol. 318, pp. 565-6, 1999.
S. Perez-Gutthann, Garcia-Rodriguez, L. A., Duque-Oliart, A., and Varas-Lorenzo, C., Low-dose diclofenac, naproxen, and ibuprofen cohort study, Pharmacotherapy, vol. 19, pp. 854-9, 1999.
M. C. Sturkenboom, Meier, C. R., Jick, H., and Stricker, B. H., Minocycline and lupuslike syndrome in acne patients, Arch Intern Med, vol. 159, pp. 493-7, 1999.
A. Ruigomez, Wallander, M. A., Johansson, S., and Rodriguez, L. A. Garcia, One-year follow-up of newly diagnosed irritable bowel syndrome patients, Aliment Pharmacol Ther, vol. 13, pp. 1097-102, 1999.
R. D. Farmer, Lawrenson, R. A., Todd, J. C., Williams, T. J., and MacRae, K., Oral contraceptives and venous thromboembolic disease. Analyses of the UK General Practice Research Database and the UK Mediplus database, Hum Reprod Update, vol. 5, pp. 688-706, 1999.
J. Edington, Winter, P. D., Coles, S. J., Gale, C. R., and Martyn, C. N., Outcomes of undernutrition in patients in the community with cancer or cardiovascular disease, Proc Nutr Soc, vol. 58, pp. 655-61, 1999.
A. Majeed and Moser, K., Prescribing for patients with asthma by general practitioners in England and Wales 1994-1996, Health Statistics Quarterly, vol. 4, pp. 5-8, 1999.
Ofor Nation Statistics, Prevalence of asthma in general practice, Asthma J, vol. 4, pp. 79-80, 1999.
S. S. Jick, Myers, M. W., and Jick, H., Risk of idiopathic cerebral haemorrhage in women on oral contraceptives with differing progestagen components, Lancet, vol. 354, pp. 302-3, 1999.
C. Vasilakis, Jick, H., and M. Melero-Montes, delMar, Risk of idiopathic venous thromboembolism in users of progestagens alone, Lancet, vol. 354, pp. 1610-1, 1999.
C. Vasilakis, Jick, S. S., and Jick, H., The risk of venous thromboembolism in users of postcoital contraceptive pills, Contraception, vol. 59, pp. 79-83, 1999.
F. J. de Abajo and Rodriguez, L. A., Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs, Br J Clin Pharmacol, vol. 47, pp. 307-13, 1999.
L. A. Garcia Rodriguez and Ruigomez, A., Secondary prevention of upper gastrointestinal bleeding associated with maintenance acid-suppressing treatment in patients with peptic ulcer bleed, Epidemiology, vol. 10, pp. 228-32, 1999.
M. Frischer, Heatlie, H., Chapman, S., Norwood, J., Bashford, J., and Millson, D., Should the corticosteroid to bronchodilator ratio be promoted as a quality prescribing marker?, Public Health, vol. 113, pp. 247-50, 1999.
M. Frisher, Heatlie, H., Chapman, S., Bashford, J., and Norwood, J., Switching between metered dose inhalers (MDIs) and dry powder inhalers (DPIs) in airways disease: An analysis of agespecific rates using the general practice research database., Journal of Applied Therapeutic Research, vol. 2, pp. 253-259, 1999.
A. Ruigomez, Rodriguez, L. A. Garcia, Cattaruzzi, C., Troncon, M. G., Agostinis, L., Wallander, M. A., and Johansson, S., Use of cimetidine, omeprazole, and ranitidine in pregnant women and pregnancy outcomes, Am J Epidemiol, vol. 150, pp. 476-81, 1999.
L. E. Derby, Myers, M. W., and Jick, H., Use of dexfenfluramine, fenfluramine and phentermine and the risk of stroke, Br J Clin Pharmacol, vol. 47, pp. 565-9, 1999.
A. Hansell, Hollowell, J., Nichols, T., McNiece, R., and Strachan, D., Use of the General Practice Research Database (GPRD) for respiratory epidemiology: a comparison with the 4th Morbidity Survey in General Practice (MSGP4), Thorax, vol. 54, pp. 413-9, 1999.
R. Hubbard and Venn, A., Adult height and cryptogenic fibrosing alveolitis: a case-control study using the UK general practice research database, Thorax, vol. 55, pp. 864-6, 2000.
A. Majeed, Moser, K., and Maxwell, R., Age, sex and practice variations in the use of statins in general practice in England and Wales, J Public Health Med, vol. 22, pp. 275-9, 2000.
C. R. Meier, Derby, L. E., Jick, S. S., and Jick, H., Angiotensin-converting enzyme inhibitors, calcium channel blockers, and breast cancer, Arch Intern Med, vol. 160, pp. 349-53, 2000.
C. R. Meier, Antibiotics in the prevention and treatment of coronary heart disease, J Infect Dis, vol. 181 Suppl 3, pp. S558-62, 2000.
M. W. Myers, Vasilakis, C., Kaufman, M. R., and Jick, H., Antihypertensive drugs and the risk of idiopathic aplastic anaemia, Br J Clin Pharmacol, vol. 49, pp. 604-8, 2000.
G. L. Zornberg and Jick, H., Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study, Lancet, vol. 356, pp. 1219-23, 2000.
A. Ruigomez, Rodriguez, L. A. Garcia, Dev, V. J., Arellano, F., and Raniwala, J., Are schizophrenia or antipsychotic drugs a risk factor for cataracts?, Epidemiology, vol. 11, pp. 620-3, 2000.
D. Millson, Frischer, M., Croft, P., and Goadsby, P. J., Are triptans with enhanced lipophilicity used for the acute treatment of migraine associated with an increased consulting rate for depressive illness?, Cephalalgia, vol. 20, pp. 732-7, 2000.
S. F. Lanes, Rodrigeuz, L. A., and Hwangg, E., Baseline risk of gastrointestinal disorders among new users of meloxicam, ibuprofen, diclofenac, naproxen and indomethacin, Pharmacoepidemiol Drug Saf, vol. 9, pp. 113-7, 2000.
R. D. Farmer, Lawrenson, R. A., Todd, J. C., Williams, T. J., MacRae, K. D., Tyrer, F., and Leydon, G. M., A comparison of the risks of venous thromboembolic disease in association with different combined oral contraceptives, Br J Clin Pharmacol, vol. 49, pp. 580-90, 2000.
M. Frischer, Norwood, J., Heatlie, H., Millson, D., Lowdell, J., Hickman, M., Chapman, S., and Bashford, J., A comparison of trends in problematic drug misuse from two reporting systems, J Public Health Med, vol. 22, pp. 362-7, 2000.
M. Frischer, Heatlie, H., Chapman, S., and Millson, D., Defining the spectrum of appropriate prescribing: implications for effective medicines management, International Journal of Pharmaceutical Medicine, vol. 14, pp. 17-21, 2000.
L. A. Garcia Rodriguez, Ruigomez, A., Wallander, M. A., Johansson, S., and Olbe, L., Detection of colorectal tumor and inflammatory bowel disease during follow-up of patients with initial diagnosis of irritable bowel syndrome, Scand J Gastroenterol, vol. 35, pp. 306-11, 2000.
L. A. Garcia Rodriguez, Varas, C., and Patrono, C., Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women, Epidemiology, vol. 11, pp. 382-7, 2000.
R. D. Farmer, Williams, T. J., Simpson, E. L., and Nightingale, A. L., Effect of 1995 pill scare on rates of venous thromboembolism among women taking combined oral contraceptives: analysis of general practice research database, Bmj, vol. 321, pp. 477-9, 2000.
M. J. Langman, Cheng, K. K., Gilman, E. A., and Lancashire, R. J., Effect of anti-inflammatory drugs on overall risk of common cancer: case-control study in general practice research database, Bmj, vol. 320, pp. 1642-6, 2000.
A. L. Nightingale, Lawrenson, R. A., Simpson, E. L., Williams, T. J., MacRae, K. D., and Farmer, R. D., The effects of age, body mass index, smoking and general health on the risk of venous thromboembolism in users of combined oral contraceptives, Eur J Contracept Reprod Health Care, vol. 5, pp. 265-74, 2000.
D. Gupta, Hansell, A., Nichols, T., Duong, T., Ayres, J. G., and Strachan, D., Epidemiology of pneumothorax in England, Thorax, vol. 55, pp. 666-71, 2000.
R. Hubbard, Venn, A., and Britton, J., Exposure to antidepressants and the risk of cryptogenic fibrosing alveolitis: a case-control study, Eur Respir J, vol. 16, pp. 409-13, 2000.
C. R. Meier, Schlienger, R. G., Kraenzlin, M. E., Schlegel, B., and Jick, H., HMG-CoA reductase inhibitors and the risk of fractures, Jama, vol. 283, pp. 3205-10, 2000.
C. Varas-Lorenzo, Garcia-Rodriguez, L. A., Perez-Gutthann, S., and Duque-Oliart, A., Hormone replacement therapy and incidence of acute myocardial infarction. A population-based nested case-control study, Circulation, vol. 101, pp. 2572-8, 2000.
G. M. Clifford, Logie, J., and Farmer, R. D., How do symptoms indicative of BPH progress in real life practice? The UK experience, Eur Urol, vol. 38 Suppl 1, pp. 48-53, 2000.
delMar M. Melero-Montes and Jick, H., Hyperemesis Gravidarum and the Sex of the Offspring, Epidemiology, vol. 12, pp. 123-124, 2000.
J. A. Kaye, Derby, L. E., M. Melero-Montes, delMar, Quinn, M., and Jick, H., The incidence of breast cancer in the General Practice Research Database compared with national cancer registration data, Br J Cancer, vol. 83, pp. 1556-8, 2000.
C. Gasse, Derby, L., Vasilakis-Scaramozza, C., and Jick, H., Incidence of first-time idiopathic seizures in users of tramadol, Pharmacotherapy, vol. 20, pp. 629-34, 2000.
H. Jick, Incidence of venous thromboembolism in users of combined oral contraceptives. Methods for identifying cases and estimating person time at risk must be detailed, Bmj, vol. 320, pp. 57; author reply 57-8, 2000.
F. J. de Abajo, Jick, H., Derby, L., Jick, S., and Schmitz, S., Intracranial haemorrhage and use of selective serotonin reuptake inhibitors, Br J Clin Pharmacol, vol. 50, pp. 43-7, 2000.
S. S. Jick, Kremers, H. M., and Vasilakis-Scaramozza, C., Isotretinoin use and risk of depression, psychotic symptoms, suicide, and attempted suicide, Arch Dermatol, vol. 136, pp. 1231-6, 2000.
R. Hubbard, Venn, A., Lewis, S., and Britton, J., Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study, Am J Respir Crit Care Med, vol. 161, pp. 5-8, 2000.
[Page last reviewed 5 August 2019]