| 2020 |
Channeling Bias in the Analysis of Risk of Myocardial Infarction, Stroke, Gastrointestinal Bleeding, and Acute Renal Failure with the Use of Paracetamol Compared with Ibuprofen
10.1007/s40264-020-00950-3
Authors: R. Weinstein, P. Ryan, J. Berlin, M. Schuemie, J. Swerdel, D. Fife |
| 2020 |
Characteristics Associated with Accelerated Lung Function Decline in a Primary Care Population with Chronic Obstructive Pulmonary Disease
10.2147/copd.s278981
Authors: H. Whittaker, J. Pimenta, D. Jarvis, S. Kiddle, J. Quint |
| 2020 |
Characteristics, service use and mortality of clusters of multimorbid patients in England: a population-based study
10.1186/s12916-020-01543-8
Authors: Y. Zhu, D. Edwards, J. Mant, R. Payne, S. Kiddle |
| 2020 |
Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database
10.2147/copd.s255414
Authors: K. Kostikas, D. Price, F. Gutzwiller, B. Jones, E. Loefroth, A. Clemens, R. Fogel, R. Jones, H. Cao |
| 2020 |
Comorbidities in patients with polymyalgia rheumatica prior to and following diagnosis: A case control and cohort study
10.1016/j.semarthrit.2020.05.003
Authors: R. Partington, S. Muller, C. Mallen, Abdul Sultan, T. Helliwell |
| 2020 |
Comparative effectiveness and safety of direct oral anticoagulants versus warfarin in UK patients with atrial fibrillation and type 2 diabetes: A retrospective cohort study
10.1002/pds.5181
Authors: Rustem Gulluoglu, P. Souverein, H. van den Ham, A. de Boer, J. Komen |
| 2020 |
Comparative effectiveness of gliclazide modified release vs sitagliptin as second-line treatment after metformin monotherapy in patients with uncontrolled type 2 diabetes
10.1111/dom.14169
Authors: F. Zaccardi, E. Jacquot, V. Cortese, F. Tyrer, S. Seidu, M. Davies, K. Khunti |
| 2020 |
Comparative effects of sulfonylureas, DPP4is and SGLT2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care
10.1111/dom.13970
Authors: S. Wilkinson, E. Williamson, A. Pokrajac, D. Fogarty, H. Stirnadel-Farrant, L. Smeeth, I. Douglas, L. Tomlinson |
| 2020 |
Comparing healthcare cost associated with the use of enzyme-inducing and non-enzyme active antiepileptic drugs in elderly patients with epilepsy in the UK: a long-term retrospective, matched cohort study
10.1186/s12883-019-1587-9
Authors: S. Borghs, L. Byram, J. Chan, P. Dedeken, J. Logan, V. Kiri, M. Noack-Rink, P. Patsalos, S. Thieffry |
| 2020 |
Comparing New-User Cohort Designs: The Example of Proton Pump Inhibitor Effectiveness in Idiopathic Pulmonary Fibrosis
10.1093/aje/kwaa242
Authors: T. Tran, S. Suissa |
| 2020 |
Comparison of antibiotic prescribing records in two UK primary care electronic health record systems: cohort study using CPRD GOLD and CPRD Aurum databases
10.1136/bmjopen-2020-038767
Authors: M. Gulliford, X. Sun, T. Anjuman, E. Yelland, T. Murray-Thomas |
| 2020 |
Comparison of antihypertensive drug classes for dementia prevention
10.1097/ede.0000000000001245
Authors: V. Walker, N. Davies, R. Martin, P. Kehoe |
| 2020 |
Comparison of long-term use of prolonged-release ropinirole and immediate-release dopamine agonists in an observational study in patients with Parkinson\textquoterights disease
10.1002/pds.4986
Authors: U. Gungabissoon, O. Kirichek, El Baou, N. Galwey |
| 2020 |
Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers: lessons for COVID-19 from a nationwide cohort study
10.12688/wellcomeopenres.15873.1
Authors: P. Bidulka, M. Iwagami, K. Mansfield, F. Kalogirou, A. Wong, I. Douglas, L. Smeeth, C. Summers, L. Tomlinson |
| 2020 |
Concomitant use of oral glucocorticoids and proton pump inhibitors and risk of osteoporotic fractures among patients with rheumatoid arthritis: a population-based cohort study
10.1136/annrheumdis-2020-218758
Authors: S. Abtahi, J. Driessen, A. Burden, P. Souverein, J. van den Bergh, T. van Staa, A. Boonen, F. de Vries |
| 2020 |
Concordance in the recording of stroke across UK primary and secondary care datasets: a population-based cohort study
10.3399/bjgpo.2020.0117
Authors: A. Morgan, S. Sinnott, L. Smeeth, C. Minassian, J. Quint |
| 2020 |
Consistency of variety of machine learning and statistical models in predicting clinical risks of individual patients: longitudinal cohort study using cardiovascular disease as exemplar
10.1136/bmj.m3919
Authors: Y. Li, M. Sperrin, D. Ashcroft, T. van Staa |
| 2020 |
Co-prescription of gabapentinoids and opioids among adults with and without osteoarthritis in the United Kingdom between 1995 and 2017
10.1093/rheumatology/keaa586
Authors: D. Yu, T. Appleyard, E. Cottrell, G. Peat |
| 2020 |
Costs of joint replacement in osteoarthritis: a study using the National Joint Registry and Clinical Practice Research Datalink datasets
10.1002/acr.24470
Authors: J. Leal, J. Murphy, C. Garriga, A. Delmestri, A. Rangan, A. Price, A. Carr, D. Prieto-Alhambra, A. Judge |
| 2020 |
Cough presentation in primary care and the identification of chronic cough: a need for diagnostic clarity?
10.1080/03007995.2019.1673716
Authors: S. Holden, A. Morice, S. Birring, S. Jenkins-Jones, H. Langerman, J. Weaver, C. Currie |
| 2020 |
Could dementia be detected from UK primary care patients\textquoteright records by simple automated methods earlier than by the treating physician? A retrospective case-control study
10.12688/wellcomeopenres.15903.1
Authors: E. Ford, J. Starlinger, P. Rooney, S. Oliver, S. Banerjee, H. van Marwijk, J. Cassell |
| 2020 |
CPRD Aurum database: Assessment of data quality and completeness of three important comorbidities
10.1002/pds.5135
Authors: R. Persson, C. Vasilakis-Scaramozza, K. Hagberg, T. Sponholtz, T. Williams, P. Myles, S. Jick |
| 2020 |
Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015)
10.1136/bmjopen-2019-034396
Authors: P. Rockenschaub, V. Nguyen, R. Aldridge, D. Acosta, J. Garcia-Gomez, C. Saez |
| 2020 |
Deep learning for electronic health records: A comparative review of multiple deep neural architectures
10.1016/j.jbi.2019.103337
Authors: J. Solares, F. Raimondi, Y. Zhu, F. Rahimian, D. Canoy, J. Tran, A. Gomes, A. Payberah, M. Zottoli, M. Nazarzadeh, N. Conrad, K. Rahimi, G. Salimi-Khorshidi |
| 2020 |
Delays in referral from primary care worsen survival for patients with colorectal cancer: a retrospective cohort study
10.3399/bjgp20X710441
Authors: C. Arhi, E. Burns, A. Bottle, G. Bouras, P. Aylin, P. Ziprin, A. Darzi |
| 2020 |
Depression in individuals who subsequently develop inflammatory bowel disease: a population-based nested case-control study
10.1136/gutjnl-2020-322308
Authors: J. Blackwell, S. Saxena, I. Petersen, M. Hotopf, H. Creese, A. Bottle, C. Alexakis, R. Pollok |
| 2020 |
Determinants of referral of women with urinary incontinence to specialist services: a national cohort study using primary care data from the UK
10.1186/s12875-020-01282-y
Authors: I. Gurol-Urganci, R. Geary, J. Mamza, M. Iwagami, D. El-Hamamsy, J. Duckett, A. Wilson, D. Tincello, J. van der Meulen |
| 2020 |
Determination of healthcare resource and cost implications of using alternative sodium valproate formulations in the treatment of epilepsy in children in England: a retrospective database review
10.1016/j.ejpb.2020.12.007
Authors: H. Batchelor |
| 2020 |
Development and Validation of a Clinical Prediction Tool for Seasonal Influenza Vaccination in England
10.1001/jamanetworkopen.2020.7743
Authors: M. Loiacono, N. Mitsakakis, J. Kwong, G. Gomez, A. Chit, P. Grootendorst |
| 2020 |
Development and Validation of a Method to Estimate COPD Severity in Multiple Datasets: A Retrospective Study
10.1007/s41030-020-00139-0
Authors: J. Quint, C. O\textquoterightLeary, A. Venerus, U. Holmgren, P. Varghese, C. Cabrera |
| 2020 |
Development and validation of a multivariable prediction model for infection-related complications in patients with common infections in UK primary care and the extent of risk-based prescribing of antibiotics
10.1186/s12916-020-01581-2
Authors: C. Mistry, V. Palin, Y. Li, G. Martin, D. Jenkins, W. Welfare, D. Ashcroft, T. Van Staa |
| 2020 |
Development and validation of the Cambridge Multimorbidity Score
10.1503/cmaj.190757
Authors: R. Payne, S. Mendonca, M. Elliott, C. Saunders, D. Edwards, M. Marshall, M. Roland |
| 2020 |
Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study
10.1136/bmjdrc-2019-000962
Authors: S. Zghebi, M. Mamas, D. Ashcroft, C. Salisbury, C. Mallen, C. Chew-Graham, D. Reeves, H. van Marwijk, N. Qureshi, S. Weng, T. Holt, I. Buchan, N. Peek, S. Giles, M. Rutter, E. Kontopantelis |
| 2020 |
Development of a structured clinical pharmacology review for specialist support for management of complex polypharmacy in primary care
10.1111/bcp.14243
Authors: C. Threapleton, J. Kimpton, I. Carey, S. DeWilde, D. Cook, T. Harris, E. Baker |
| 2020 |
The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study
10.1371/journal.pmed.1003295
Authors: G. Funston, W. Hamilton, G. Abel, E. Crosbie, B. Rous, F. Walter |
| 2020 |
Disease Activity in Inflammatory Bowel Disease Is Associated With Arterial Vascular Disease
10.1093/ibd/izaa156
Authors: T. Card, E. Zittan, G. Nguyen, M. Grainge |
| 2020 |
Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study
10.1371/journal.pmed.1003432
Authors: M. Pujades-Rodriguez, A. Morgan, R. Cubbon, J. Wu |
| 2020 |
The economic burden of infections following intramedullary nailing for a tibial shaft fracture in England
10.1136/bmjopen-2019-035404
Authors: T. Galvain, A. Chitnis, K. Paparouni, C. Tong, C. Holy, P. Giannoudis |
| 2020 |
Effect of bariatric surgery on long-term cardiovascular outcomes: a nationwide nested cohort study
10.1093/eurheartj/ehaa069
Authors: O. Moussa, M. Ardissino, T. Heaton, A. Tang, O. Khan, P. Ziprin, A. Darzi, P. Collins, S. Purkayastha |
| 2020 |
The effect of initiation of renin-angiotensin system inhibitors on haemoglobin: A national cohort study
10.1111/bcp.14429
Authors: G. Greenhall, K. Mansfield, D. Nitsch, M. Iwagami, C. Leyrat, R. Johnston, L. Smeeth, L. Tomlinson |
| 2020 |
Effect of pre-existing conditions on bladder cancer stage at diagnosis: a cohort study using electronic primary care records in the UK
10.3399/bjgp20X710921
Authors: M. Carney, M. Quiroga, L. Mounce, E. Shephard, W. Hamilton, S. Price |
| 2020 |
The effectiveness of frequent antibiotic use in reducing the risk of infection-related hospital admissions: results from two large population-based cohorts
10.1186/s12916-020-1504-5
Authors: T. van Staa, V. Palin, Y. Li, W. Welfare, T. Felton, P. Dark, D. Ashcroft |
| 2020 |
Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease-modifying anti-rheumatic drugs
10.1093/rheumatology/keaa078
Authors: G. Nakafero, M. Grainge, P. Myles, C. Mallen, W. Zhang, M. Doherty, J. Nguyen-Van-Tam, A. Abhishek |
| 2020 |
Effectiveness of proton pump inhibitors in idiopathic pulmonary fibrosis: a population-based cohort study
10.1016/j.chest.2020.08.2080
Authors: T. Tran, D. Assayag, P. Ernst, S. Suissa |
| 2020 |
Eleven-year multimorbidity burden among 637 255 people with and without type 2 diabetes: a population-based study using primary care and linked hospitalisation data
10.1136/bmjopen-2019-033866
Authors: S. Zghebi, D. Steinke, M. Rutter, D. Ashcroft |
| 2020 |
Epidemiology and determinants of non-diabetic hyperglycaemia and its conversion to type 2 diabetes mellitus, 2000-2015: cohort population study using UK electronic health records
10.1136/bmjopen-2020-040201
Authors: R. Ravindrarajah, D. Reeves, E. Howarth, R. Meacock, C. Soiland-Reyes, S. Cotterill, W. Whittaker, S. Heller, M. Sutton, P. Bower, E. Kontopantelis |
| 2020 |
Epidemiology and outcomes of gastroparesis, as documented in general practice records, in the United Kingdom
10.1136/gutjnl-2020-321277
Authors: Y. Ye, B. Jiang, S. Manne, P. Moses, C. Almansa, D. Bennett, P. Dolin, A. Ford |
| 2020 |
The Epidemiology of Malignant Melanoma, Squamous Cell Carcinoma, and Basal Cell Carcinoma in the United Kingdom from 2004-2014: A Population-Based Cohort Analysis using the Clinical Practice Research Datalink
10.1111/bjd.19542
Authors: F. Mirza, S. Yumeen, F. Walter |
| 2020 |
Epidemiology of systemic sclerosis in the UK: an analysis of the Clinical Practice Research Datalink
10.1093/rheumatology/keaa680
Authors: J. Pauling, A. McGrogan, J. Snowball, N. McHugh |
| 2020 |
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study
10.1136/bmjopen-2020-043828
Authors: A. Lai, L. Pasea, A. Banerjee, G. Hall, S. Denaxas, W. Chang, M. Katsoulis, B. Williams, D. Pillay, M. Noursadeghi, D. Linch, D. Hughes, M. Forster, C. Turnbull, N. Fitzpatrick, K. Boyd, G. Foster, T. Enver, V. Nafilyan, B. Humberstone, R. Neal, M. Cooper, M. Jones, K. Pritchard-Jones, R. Sullivan, C. Davie, M. Lawler, H. Hemingway |
