Bibliography

Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 3,500 peer-reviewed publications. The CPRD bibliography listed below is updated on a monthly basis (last updated 8 May 2024).

If you have published papers using CPRD data which are not included in this list, please contact us at enquiries@cprd.com so that we can update the bibliography.

Download: CPRD bibliography PDF March 2024 (PDF, 4.2MB, 313 pages) 

This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website

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Year Title Sort descending
2023

Persistent high prevalence of modifiable cardiovascular risk factors among patients with osteoarthritis in the UK in 1992-2017

10.1136/rmdopen-2023-003298

Authors: D. Yu, X. Huang, M. Mamas, R. Wilkie

2023

Persistent inequalities in consultation incidence and prevalence of low back pain and osteoarthritis in England between 2004 and 2019

10.1093/rap/rkac106

Authors: D. Yu, K. Jordan, R. Wilkie, J. Bailey, J. Fitzpatrick, N. Ali, P. Niblett, G. Peat

2020

Persistent postoperative pain and healthcare costs associated with instrumented and non-instrumented spinal surgery: a case-control study

10.1186/s13018-020-01633-6

Authors: S. Weir, M. Samnaliev, T. Kuo, T. Tierney, A. Manca, R. Taylor, J. Bruce, S. Eldabe, D. Cumming

2024

Persons diagnosed with COVID-19 in England in the Clinical Practice Research Datalink (CPRD): a cohort description

10.1136/bmjopen-2023-073866

Authors: K. Andersen, L. McGrath, M. Reimbaeva, D. Mendes, J. Nguyen, K. Rai, T. Tritton, C. Tsang, D. Malhotra, J. Yang

2004

Pharmaceutical treatment of symptomatic vertebral fractures in primary care

10.1136/ard.2003.013508

Authors: D. Torgerson, D. Sykes, S. Puffer, P. Brown, C. Cooper

2019

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

10.1371/journal.pone.0218115

Authors: J. Floyd, K. Bloch, J. Brody, C. Maroteau, M. Siddiqui, R. Gregory, D. Carr, M. Molokhia, X. Liu, J. Bis, A. Ahmed, X. Liu, P. Hallberg, Q . Y. Yue, P. Magnusson, D. Brisson, K. Wiggins, A. Morrison, E. Khoury, P. McKeigue, B. Stricker, M. Lapeyre-Mestre, S. Heckbert, A. Gallagher, H. Chinoy, R. Gibbs, E. Bondon-Guitton, R. Tracy, E. Boerwinkle, D. Gaudet, A. Conforti, T. Van Staa, C. Sitlani, K. Rice, A. van der Zee, M. Wadelius, A. Morris, M. Pirmohamed, C. Palmer, B. Psaty, A. Alfirevic

2017

Pharmacologic Differences of Sulfonylureas and the Risk of Adverse Cardiovascular and Hypoglycemic Events

10.2337/dc17-0595

Authors: A. Douros, H. Yin, O. H. Y. Yu, K. Filion, L. Azoulay, S. Suissa

2023

Pharmacologic heterogeneity and risk of severe hypoglycemia with concomitant use of sulfonylureas and DPP-4 inhibitors: population-based cohort study

10.1002/cpt.2975

Authors: J. Dimakos, Y. Cui, R. Platt, C. Renoux, K. Filion, A. Douros

2018

Pharmacological intervention in hypertension using beta-blockers: Real-world evidence for long-term effectiveness

10.1016/j.phrs.2018.01.010

Authors: M. Sabido, T. Hohenberger, G. Grassi

2023

Pharmacologically Treated Anxiety and Depression in People Diagnosed with von Willebrand Disease: Matched Cohort Study

10.2147/jbm.s407993

Authors: K. Hagberg, S. Jick, G. Ozen, P. Du

2016

Pharmacosurveillance without borders: electronic health records in different countries can be used to address important methodological issues in estimating the risk of adverse events

10.1016/j.jclinepi.2016.03.033

Authors: R. Tamblyn, N. Girard, W. Dixon, J. Haas, D. Bates, T. Sheppard, T. Eguale, D. Buckeridge, M. Abrahamowicz, A. Forster

2015

Pharmacotherapeutic strategies for patients treated for depression in UK primary care: a database analysis

10.1185/03007995.2015.1020362

Authors: F. Lamy, J. Chollet, E. Clay, M. Brignone, B. Rive, D. Saragoussi

2023

Phenotypes and rates of cancer-relevant symptoms and tests in the year before cancer diagnosis in UK Biobank and CPRD Gold

10.1371/journal.pdig.0000383

Authors: M. Barclay, C. Renzi, A. Antoniou, S. Denaxas, H. Harrison, S. Ip, N. Pashayan, A. Torralbo, J. Usher-Smith, A. Wood, G. Lyratzopoulos

2016

Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink

10.1371/journal.pmed.1002037

Authors: A. Matthews, S. Langan, I. Douglas, L. Smeeth, K. Bhaskaran

2016

Phosphodiesterase Type 5 Inhibitors and the Risk of Melanoma Skin Cancer

10.1016/j.eururo.2016.04.035

Authors: Y. Lian, H. Yin, M. Pollak, S. Carrier, R. Platt, S. Suissa, L. Azoulay

2010

Phynx: an open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases

10.1002/pds.1860

Authors: M. Egbring, G. Kullak-Ublick, S. Russmann

2006

Physical and psychological co-morbidity in irritable bowel syndrome: a matched cohort study using the General Practice Research Database

10.1111/j.1365-2036.2006.03044.x

Authors: R. Jones, R. Latinovic, J. Charlton, M. Gulliford

2017

Physician Support of Smoking Cessation After Diagnosis of Lung, Bladder, or Upper Aerodigestive Tract Cancer

10.1370/afm.2100

Authors: A. Farley, C. Koshiaris, J. Oke, R. Ryan, L. Szatkowski, R. Stevens, P. Aveyard

2013

Physicians\textquoteright prescribing preferences were a potential instrument for patients\textquoteright actual prescriptions of antidepressants

10.1016/j.jclinepi.2013.06.008

Authors: N. Davies, D. Gunnell, K. Thomas, C. Metcalfe, F. Windmeijer, R. Martin

2015

Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis

10.1007/s00125-014-3456-9

Authors: D. Levin, S. Bell, R. Sund, S. Hartikainen, J. Tuomilehto, E. Pukkala, I. Keskimaki, E. Badrick, A. Renehan, I. Buchan, S. Bowker, J. Minhas-Sandhu, Z. Zafari, C. Marra, J. Johnson, B. Stricker, A. Uitterlinden, A. Hofman, R. Ruiter, C. de Keyser, T. MacDonald, S. Wild, P. McKeigue, H. Colhoun

2013

Pioglitazone and bladder cancer: a propensity score matched cohort study

10.1111/j.1365-2125.2012.04325.x

Authors: L. Wei, T. MacDonald, I. Mackenzie

2018

Pioglitazone and cause-specific risk of mortality in patients with type 2 diabetes: extended analysis from a European multidatabase cohort study

10.1136/bmjdrc-2017-000481

Authors: H. Strongman, S. Christopher, M. Majak, R. Williams, S. Bahmanyar, M. Linder, E. Heintjes, D. Bennett, P. Korhonen, F. Hoti

2017

Pioglitazone and risk of mortality in patients with type 2 diabetes: results from a European multidatabase cohort study

10.1136/bmjdrc-2016-000364

Authors: H. Strongman, P. Korhonen, R. Williams, S. Bahmanyar, F. Hoti, S. Christopher, M. Majak, L. Kool-Houweling, M. Linder, P. Dolin, E. Heintjes

2016

Pioglitazone use and risk of bladder cancer in patients with type 2 diabetes: retrospective cohort study using datasets from four European countries

10.1136/bmj.i3903

Authors: P. Korhonen, E. Heintjes, R. Williams, F. Hoti, S. Christopher, M. Majak, L. Kool-Houweling, H. Strongman, M. Linder, P. Dolin, S. Bahmanyar

2016

Pioglitazone use and risk of bladder cancer: population based cohort study

10.1136/bmj.i1541

Authors: M. Tuccori, K. Filion, H. Yin, O. Yu, R. Platt, L. Azoulay

2016

PLEASANT: Preventing and Lessening Exacerbations of Asthma in School-age children Associated with a New Term - a cluster randomised controlled trial and economic evaluation

10.3310/hta20930

Authors: S. Julious, M. Horspool, S. Davis, M. Bradburn, P. Norman, N. Shephard, C. Cooper, W. Smithson, J. Boote, H. Elphick, A. Loban, M. Franklin, W. Kua, R. May, J. Campbell, R. Williams, S. Rex, O. Bortolami

2006

Pneumococcal polysaccharide vaccine uptake in England, 1989-2003, prior to the introduction of a vaccination programme for older adults

10.1093/pubmed/fdl017

Authors: K. Noakes, R. Pebody, U. Gungabissoon, J. Stowe, E. Miller

2020

Pneumococcal vaccine coverage among individuals aged 18 to 64 years old with underlying medical conditions in the UK: a retrospective database analysis

10.1186/s12889-020-09613-5

Authors: I. Matthews, X. Lu, Q. Xia, W. Black, B. Nozad

2019

Pneumonia incidence trends in UK primary care from 2002 to 2017: population-based cohort study

10.1017/s0950268819001559

Authors: X. Sun, A. Douiri, M. Gulliford

2014

Point-of-care cluster randomized trial in stroke secondary prevention using electronic health records

10.1161/strokeaha.114.005713

Authors: A. Dregan, T. van Staa, L. McDermott, G. McCann, M. Ashworth, J. Charlton, C. Wolfe, A. Rudd, L. Yardley, M. Gulliford, Committee Steering

2018

Poisoning substances taken by young people: a population-based cohort study

10.3399/bjgp18X698897

Authors: E. Tyrrell, D. Kendrick, K. Sayal, E. Orton

2018

Polycystic ovary syndrome and autism: A test of the prenatal sex steroid theory

10.1038/s41398-018-0186-7

Authors: A. Cherskov, A. Pohl, C. Allison, H. Zhang, R. Payne, S. Baron-Cohen

2022

Polycystic ovary syndrome and risk of adverse obstetric outcomes: a retrospective population-based matched cohort study in England

10.1186/s12916-022-02473-3

Authors: A. Subramanian, S. Lee, K. Phillips, K. Toulis, P. Kempegowda, M. O'Reilly, N. Adderley, S. Thangaratinam, W. Arlt, K. Nirantharakumar

2018

Polycystic Ovary Syndrome Is Associated With Adverse Mental Health and Neurodevelopmental Outcomes

10.1210/jc.2017-02667

Authors: T. Berni, C. Morgan, E. Berni, D. Rees

2021

Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses

10.1371/journal.pmed.1003498

Authors: L. Sun, L. Pennells, S. Kaptoge, C. Nelson, S. Ritchie, G. Abraham, M. Arnold, S. Bell, T. Bolton, S. Burgess, F. Dudbridge, Q. Guo, E. Sofianopoulou, D. Stevens, J. Thompson, A. Butterworth, A. Wood, J. Danesh, N. Samani, M. Inouye, E. Di Angelantonio

2023

Polypharmacy and antidepressant acceptability in comorbid depression and type 2 diabetes: a cohort study using UK primary care data

10.3399/bjgp.2022.0295

Authors: A. Jeffery, C. Bhanu, K. Walters, I. Wong, D. Osborn, J. Hayes

2023

Polypharmacy during pregnancy and associated risk factors: a retrospective analysis of 577 medication exposures among 1.5 million pregnancies in the UK, 2000-2019

10.1186/s12916-022-02722-5

Authors: A. Subramanian, A. Azcoaga-Lorenzo, A. Anand, K. Phillips, S. Lee, N. Cockburn, A. Fagbamigbe, C. Damase-Michel, C. Yau, C. McCowan, D. O'Reilly, G. Santorelli, H. Hope, J. Kennedy, K. Abel, K. Eastwood, L. Locock, M. Black, M. Loane, N. Moss, R. Plachcinski, S. Thangaratinam, S. Brophy, U. Agrawal, Z. Vowles, P. Brocklehurst, H. Dolk, C. Nelson-Piercy, K. Nirantharakumar

2019

Polypharmacy patterns in the last year of life in patients with dementia

10.1007/s00228-019-02721-1

Authors: R. Denholm, R. Morris, R. Payne

2024

Pooling of primary care electronic health record (EHR) data on Huntington's disease (HD) and cancer: establishing comparability of two large UK databases

10.1136/bmjopen-2022-070258

Authors: D. Dedman, R. Williams, K. Bhaskaran, I. Douglas

2018

Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia

10.1530/eje-17-0895

Authors: S. Jenkins-Jones, L. Parviainen, J. Porter, M. Withe, M. Whitaker, S. Holden, C. Morgan, C. Currie, R. Ross

2015

Poorly controlled type 2 diabetes mellitus is associated with a decreased risk of incident gout: a population-based case-control study

10.1136/annrheumdis-2014-205337

Authors: S. Bruderer, M. Bodmer, S. Jick, C. Meier

2002

Population need for coronary revascularisation: are national targets for England credible?

Authors: R. Martin, H. Hemingway, D. Gunnell, K. Karsch, A. Baumbach, S. Frankel

2016

Population prevalence of Down\textquoterights syndrome in the United Kingdom

10.1111/jir.12277

Authors: M. Alexander, Y. Ding, N. Foskett, H. Petri, C. Wandel, O. Khwaja

2017

Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014

10.1136/bmjopen-2016-014444

Authors: R. Mathur, K. Bhaskaran, E. Edwards, H. Lee, N. Chaturvedi, L. Smeeth, I. Douglas

2017

Population trends in the incidence and initial management of osteoarthritis: age-period-cohort analysis of the Clinical Practice Research Datalink, 1992-2013

10.1093/rheumatology/kex270

Authors: D. Yu, K. Jordan, J. Bedson, M. Englund, F. Blyth, A. Turkiewicz, D. Prieto-Alhambra, G. Peat

2018

Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis suppurativa

10.1111/bjd.16101

Authors: J. Ingram, S. Jenkins-Jones, D. Knipe, C. Morgan, R. Cannings-John, V. Piguet

2014

Population-based cohort study of warfarin-treated patients with atrial fibrillation: incidence of cardiovascular and bleeding outcomes

10.1136/bmjopen-2013-003839

Authors: A. Gallagher, T. van Staa, T. Murray-Thomas, N. Schoof, A. Clemens, D. Ackermann, D. Bartels

2024

Population-based study of alcohol-related liver disease in England 2001-2018: Influence of socioeconomic position

10.14309/ajg.0000000000002677

Authors: G. Askgaard, P. Jepsen, M. Jensen, A. Kann, J. Morling, F. Kraglund, T. Card, C. Crooks, J. West

2013

Population-based study of presentation and adverse outcomes after femoral hernia surgery

10.1002/bjs.9336

Authors: D. Humes, R. Radcliffe, C. Camm, J. West

2000

Population-based study on incidence, risk factors, clinical complications and drug utilisation associated with influenza in the United Kingdom

Authors: C. Meier, P. Napalkov, Y. Wegmuller, T. Jefferson, H. Jick