2016 |
High Dose Atorvastatin Associated with Increased Risk of Significant Hepatotoxicity in Comparison to Simvastatin in UK GPRD Cohort
10.1371/journal.pone.0151587
Authors: A. Clarke, P. Johnson, G. Hall, I. Ford, P. Mills |
2016 |
High risk of drug-induced microscopic colitis with concomitant use of NSAIDs and proton pump inhibitors
10.1111/apt.13583
Authors: B. Verhaegh, F. de Vries, A. Masclee, A. Keshavarzian, A. de Boer, P. Souverein, M. Pierik, D. Jonkers |
2016 |
Hip/femur fractures associated with the use of benzodiazepines (anxiolytics, hypnotics and related drugs): a methodological approach to assess consistencies across databases from the PROTECT-EU project
10.1002/pds.3816
Authors: G. Requena, C. Huerta, H. Gardarsdottir, J. Logie, R. Gonzalez-Gonzalez, V. Abbing-Karahagopian, M. Miret, C. Schneider, P. Souverein, D. Webb, A. Afonso, N. Boudiaf, E. Martin, B. Oliva, A. Alvarez, M. de Groot, A. Bate, S. Johansson, R. Schlienger, R. Reynolds, O. Klungel, F. de Abajo |
2016 |
Identification of impaired fasting glucose, healthcare utilization and progression to diabetes in the UK using the Clinical Practice Research Datalink (CPRD)
10.1002/pds.4007
Authors: J. Hong, A. McNeill, J. He, Y. Chen, K. Brodovicz |
2016 |
Identification of incident poisoning, fracture and burn events using linked primary care, secondary care and mortality data from England: implications for research and surveillance
10.1136/injuryprev-2015-041561
Authors: R. Baker, L. Tata, D. Kendrick, E. Orton |
2016 |
Impact of gout on the risk of atrial fibrillation
10.1093/rheumatology/kev418
Authors: C. Kuo, M. Grainge, C. Mallen, W. Zhang, M. Doherty |
2016 |
The impact of persistence with bisphosphonates on health resource utilization and fracture risk in the UK: a study of patient records from the UK Clinical Practice Research Datalink
10.1111/jep.12422
Authors: S. Ferguson, Feudjo Tepie, A. Taylor, A. Roddam, C. Critchlow, M. Iqbal, L. Spangler, J. Bayly |
2016 |
Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data
10.1136/bmj.i3283
Authors: A. Matthews, E. Herrett, A. Gasparrini, T. Van Staa, B. Goldacre, L. Smeeth, K. Bhaskaran |
2016 |
The Impact of the Choice of Data Source in Record Linkage Studies Estimating Mortality in Venous Thromboembolism
10.1371/journal.pone.0148349
Authors: A. Gallagher, T. Williams, H. Leufkens, F. de Vries |
2016 |
Impact of the National Health Service Health Check on cardiovascular disease risk: a difference-in-differences matching analysis
10.1503/cmaj.151201
Authors: K. Chang, J. Lee, E. Vamos, M. Soljak, D. Johnston, K. Khunti, A. Majeed, C. Millett |
2016 |
Impact of varying outcomes and definitions of suicidality on the associations of antiepileptic drugs and suicidality: comparisons from UK Clinical Practice Research Datalink (CPRD) and Danish national registries (DNR)
10.1002/pds.3928
Authors: M. Schuerch, C. Gasse, N. Robinson, Y. Alvarez, R. Walls, O. Mors, J. Christensen, U. Hesse, M. de Groot, R. Schlienger, R. Reynolds, O. Klungel, F. de Vries |
2016 |
Importance of feasibility assessments before implementing non-interventional pharmacoepidemiologic studies of vaccines: lessons learned and recommendations for future studies
10.1002/pds.4081
Authors: C. Willame, L. Baril, J. van den Bosch, G. Ferreira, R. Williams, D. Rosillon, C. Cohet |
2016 |
Improved incidence estimates from linked vs. stand-alone electronic health records
10.1016/j.jclinepi.2016.01.005
Authors: E. Millett, J. Quint, B. De Stavola, L. Smeeth, S. Thomas |
2016 |
Improving the Identification of Out-of-Hospital Sudden Cardiac Deaths in a General Practice Research Database
10.1007/s40801-016-0086-1
Authors: C. Varas-Lorenzo, A. Arana, C. Johannes, L. McQuay, K. Rothman, D. Fife |
2016 |
The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012
10.1136/annrheumdis-2014-206334
Authors: F. Rees, M. Doherty, M. Grainge, G. Davenport, P. Lanyon, W. Zhang |
2016 |
Incidence of adult Huntington\textquoterights disease in the UK: a UK-based primary care study and a systematic review
10.1136/bmjopen-2015-009070
Authors: N. Wexler, L. Collett, A. Wexler, M. Rawlins, S. Tabrizi, I. Douglas, L. Smeeth, S. Evans |
2016 |
Incidence rates of suicidal behaviors and treated depression in patients with and without psoriatic arthritis using the Clinical Practice Research Datalink
10.3109/14397595.2015.1136726
Authors: K. Hagberg, L. Li, M. Peng, K. Shah, M. Paris, S. Jick |
2016 |
Inflammatory Bowel Disease and the Risk of Autoimmune Diseases
10.1093/ecco-jcc/jjv193
Authors: J. Wilson, R. Furlano, S. Jick, C. Meier |
2016 |
Influenza and Pneumococcal Vaccination Uptake in Patients with Rheumatoid Arthritis Treated with Immunosuppressive Therapy in the UK: A Retrospective Cohort Study Using Data from the Clinical Practice Research Datalink
10.1371/journal.pone.0153848
Authors: R. Costello, K. Winthrop, S. Pye, B. Brown, W. Dixon |
2016 |
Influenza infections and risk of Alzheimer\textquoterights disease
10.1016/j.bbi.2016.03.014
Authors: P. Imfeld, S. Toovey, S. Jick, C. Meier |
2016 |
Influenza-attributable burden in United Kingdom primary care
10.1017/s0950268815001119
Authors: D. Fleming, R. Taylor, F. Haguinet, C. Schuck-Paim, J. Logie, D. Webb, R. Lustig, G. Matias |
2016 |
Instrumental variable analysis as a complementary analysis in studies of adverse effects: venous thromboembolism and second-generation versus third-generation oral contraceptives
10.1002/pds.3956
Authors: A. Boef, P. Souverein, J. Vandenbroucke, van Vlieg, A. de Boer, S. le Cessie, O. Dekkers |
2016 |
Insulin glargine use and breast cancer risk: Associations with cumulative exposure
10.3109/0284186x.2016.1155736
Authors: P. Peeters, M. Bazelier, H. Leufkens, A. Auvinen, T. van Staa, F. de Vries, M. De Bruin |
2016 |
Intrauterine device use and the risk of pre-eclampsia: a case-control study
10.1111/1471-0528.13413
Authors: S. Parker, S. Jick, M. Werler |
2016 |
Job dissatisfaction and the older worker: baseline findings from the Health and Employment After Fifty study
10.1136/oemed-2016-103591
Authors: S. D\textquoterightAngelo, D. Coggon, E. Harris, C. Linaker, A. Sayer, C. Gale, M. Evandrou, T. Van Staa, C. Cooper, K. Walker-Bone, K. Palmer |
2016 |
Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence
10.1136/bmjopen-2015-010508
Authors: R. Beau-Lejdstrom, I. Douglas, S. Evans, L. Smeeth |
2016 |
Lifestyle factors, psychiatric and neurologic comorbidities, and drug use associated with incident seizures among adult patients with depression: a population-based nested case-control study
10.1007/s10654-016-0156-4
Authors: M. Bloechliger, A. Ceschi, S. Ruegg, S. Jick, C. Meier, M. Bodmer |
2016 |
Linking e-health records, patient-reported symptoms and environmental exposure data to characterise and model COPD exacerbations: protocol for the COPE study
10.1136/bmjopen-2016-011330
Authors: E. Moore, L. Chatzidiakou, R. Jones, L. Smeeth, S. Beevers, F. Kelly, Quint J, B. Barratt |
2016 |
Maternal Pre-pregnancy Body Mass Index and Autism Spectrum Disorder among Offspring: A Population-Based Case-Control Study
10.1111/ppe.12306
Authors: K. Getz, M. Anderka, M. Werler, S. Jick |
2016 |
Menopausal hormone therapy use and risk of primary liver cancer in the clinical practice research datalink
10.1002/ijc.29960
Authors: K. McGlynn, K. Hagberg, J. Chen, M. Braunlin, B. Graubard, N. Suneja, S. Jick, V. Sahasrabuddhe |
2016 |
Metabolic syndrome in relation to Barrett\textquoterights esophagus and esophageal adenocarcinoma: Results from a large population-based case-control study in the Clinical Practice Research Datalink
10.1016/j.canep.2016.02.008
Authors: J. Drahos, L. Li, S. Jick, M. Cook |
2016 |
Metformin use and survival after colorectal cancer: A population-based cohort study
10.1002/ijc.29720
Authors: U. Menamin, L. Murray, C. Hughes, C. Cardwell |
2016 |
Metformin use and survival from lung cancer: A population-based cohort study
10.1016/j.lungcan.2016.01.012
Authors: U. Menamin, C. Cardwell, C. Hughes, L. Murray |
2016 |
A methodological comparison of two European primary care databases and replication in a US claims database: inhaled long-acting beta-2-agonists and the risk of acute myocardial infarction
10.1007/s00228-016-2071-8
Authors: A. Afonso, S. Schmiedl, C. Becker, S. Tcherny-Lessenot, P. Primatesta, E. Plana, P. Souverein, Y. Wang, J. Korevaar, J. Hasford, R. Reynolds, M. de Groot, R. Schlienger, O. Klungel, M. Rottenkolber |
2016 |
Microvascular disease and risk of cardiovascular events among individuals with type 2 diabetes: a population-level cohort study
10.1016/s2213-8587(16)30057-2
Authors: J. Brownrigg, C. Hughes, D. Burleigh, A. Karthikesalingam, B. Patterson, P. Holt, M. Thompson, S. de Lusignan, K. Ray, R. Hinchliffe |
2016 |
Model-based cost-effectiveness analysis of B-type natriuretic peptide-guided care in patients with heart failure
10.1136/bmjopen-2016-014010
Authors: S. Mohiuddin, B. Reeves, M. Pufulete, R. Maishman, M. Dayer, J. Macleod, T. McDonagh, S. Purdy, C. Rogers, W. Hollingworth |
2016 |
Modelling and extraction of variability in free-text medication prescriptions from an anonymised primary care electronic medical record research database
10.1186/s12911-016-0255-x
Authors: G. Karystianis, T. Sheppard, W. Dixon, G. Nenadic |
2016 |
Modelling Conditions and Health Care Processes in Electronic Health Records: An Application to Severe Mental Illness with the Clinical Practice Research Datalink
10.1371/journal.pone.0146715
Authors: I. Olier, D. Springate, D. Ashcroft, T. Doran, D. Reeves, C. Planner, S. Reilly, E. Kontopantelis |
2016 |
Modelling estimates of the burden of respiratory syncytial virus infection in children in the UK
10.1136/bmjopen-2015-009337
Authors: S. Taylor, R. Taylor, R. Lustig, C. Schuck-Paim, F. Haguinet, D. Webb, J. Logie, G. Matias, D. Fleming |
2016 |
Molluscum contagiosum and associations with atopic eczema in children: a retrospective longitudinal study in primary care
10.3399/bjgp15X688093
Authors: J. Olsen, V. Piguet, J. Gallacher, N. Francis |
2016 |
Morbidity and medication in a large population of individuals with Down syndrome compared to the general population
10.1111/dmcn.12868
Authors: M. Alexander, H. Petri, Y. Ding, C. Wandel, O. Khwaja, N. Foskett |
2016 |
Mortality Among Adults With Intellectual Disability in England: Comparisons With the General Population
10.2105/ajph.2016.303240
Authors: F. Hosking, I. Carey, S. Shah, T. Harris, S. DeWilde, C. Beighton, D. Cook |
2016 |
Mortality in systemic lupus erythematosus in the United Kingdom 1999-2012
10.1093/rheumatology/kev424
Authors: F. Rees, M. Doherty, M. Grainge, P. Lanyon, G. Davenport, W. Zhang |
2016 |
A Multicenter Observational Study of Incretin-based Drugs and Heart Failure
10.1056/NEJMoa1506115
Authors: K. Filion, L. Azoulay, R. Platt, M. Dahl, C. Dormuth, K. Clemens, N. Hu, J. Paterson, L. Targownik, T. Turin, J. Udell, P. Ernst |
2016 |
No association between exacerbation frequency and stroke in patients with COPD
10.2147/copd.s95775
Authors: C. Windsor, E. Herrett, L. Smeeth, J. Quint |
2016 |
Non-Persistence and Non-Adherence of Patients with Type 2 Diabetes Mellitus in Therapy with GLP-1 Receptor Agonists: A Retrospective Analysis
10.1007/s13300-015-0149-4
Authors: T. Wilke, S. Mueller, A. Groth, B. Berg, A. Fuchs, M. Sikirica, J. Logie, A. Martin, U. Maywald |
2016 |
Non-Response to Antibiotic Treatment in Adolescents for Four Common Infections in UK Primary Care 1991-2012: A Retrospective, Longitudinal Study
10.3390/antibiotics5030025
Authors: E. Berni, L. Scott, S. Jenkins-Jones, H. de Voogd, M. Rocha, C. Butler, C. Morgan, C. Currie |
2016 |
Occurrence and Recurrence of Attempted Suicide Among People With Epilepsy
10.1001/jamapsychiatry.2015.2516
Authors: D. Hesdorffer, L. Ishihara, D. Webb, L. Mynepalli, N. Galwey, W. Hauser |
2016 |
Is omission of free text records a possible source of data loss and bias in Clinical Practice Research Datalink studies? A case-control study
10.1136/bmjopen-2016-011664
Authors: S. Price, S. Stapley, E. Shephard, K. Barraclough, W. Hamilton |
2016 |
Opportunities and Challenges in Developing a Cohort of Patients with Type 2 Diabetes Mellitus Using Electronic Primary Care Data
10.1371/journal.pone.0162236
Authors: P. Datta-Nemdharry, A. Thomson, J. Beynon |