| 2018 |
Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results
10.1136/bmjopen-2017-019475
Authors: K. Wing, E. Williamson, J. Carpenter, L. Wise, S. Schneeweiss, L. Smeeth, J. Quint, I. Douglas |
| 2018 |
Real-world presentation with heart failure in primary care: do patients selected to follow diagnostic and management guidelines have better outcomes?
10.1136/openhrt-2018-000935
Authors: A. Bottle, D. Kim, P. Aylin, F. Majeed, M. Cowie, B. Hayhoe |
| 2018 |
Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research
10.1038/s41533-018-0089-3
Authors: J. Quint, E. Moore, A. Lewis, M. Hashmi, K. Sultana, M. Wright, L. Smeeth, L. Chatzidiakou, R. Jones, S. Beevers, S. Kolozali, F. Kelly, B. Barratt |
| 2018 |
Reintervention After Antireflux Surgery for Gastroesophageal Reflux Disease in England
10.1097/sla.0000000000003131
Authors: S. Markar, C. Arhi, T. Wiggins, A. Vidal-Diez, A. Karthikesalingam, A. Darzi, J. Lagergren, G. Hanna |
| 2018 |
Relative toxicity of benzodiazepines and hypnotics commonly used for self-poisoning: An epidemiological study of fatal toxicity and case fatality
10.1177/0269881118754734
Authors: G. Geulayov, A. Ferrey, D. Casey, C. Wells, A. Fuller, C. Bankhead, D. Gunnell, C. Clements, N. Kapur, J. Ness, K. Waters, K. Hawton |
| 2018 |
Relative toxicity of mood stabilisers and antipsychotics: case fatality and fatal toxicity associated with self-poisoning
10.1186/s12888-018-1993-3
Authors: A. Ferrey, G. Geulayov, D. Casey, C. Wells, A. Fuller, C. Bankhead, J. Ness, C. Clements, D. Gunnell, N. Kapur, K. Hawton |
| 2018 |
Reliability of coded data to identify earliest indications of cognitive decline, cognitive evaluation and Alzheimer\textquoterights disease diagnosis: a pilot study in England
10.1136/bmjopen-2017-019684
Authors: G. Dell\textquoterightAgnello, U. Desai, N . Y. Kirson, J. Wen, M. Meiselbach, C. Reed, M. Belger, A. Lenox-Smith, C. Martinez, J. Rasmussen |
| 2018 |
Representativeness of a digitally engaged population and a patient organisation population with rheumatoid arthritis and their willingness to participate in research: a cross-sectional study
10.1136/rmdopen-2018-000664
Authors: R. Costello, C. Jacklin, Jameson Evans, J. McBeth, W. Dixon |
| 2018 |
A retrospective observational analysis of post-pandemic influenza-related outcomes in the United Kingdom, 2010-2014
10.1080/21645515.2017.1403696
Authors: S. Rajaram, W. Wiecek, R. Lawson, B. Blak, Y. Zhao, J. Hackett, R. Brody, T. Salimi, B. Amzal, V. Patel |
| 2018 |
Rheumatoid arthritis and excess mortality: down but not out. A primary care cohort study using data from Clinical Practice Research Datalink
10.1093/rheumatology/key013
Authors: A. Abhishek, G. Nakafero, C. Kuo, C. Mallen, W. Zhang, M. Grainge, M. Doherty |
| 2018 |
Risk Associated with Cumulative Oral Glucocorticoid Use in Patients with Giant Cell Arteritis in Real-World Databases from the USA and UK
10.1007/s40744-018-0112-8
Authors: S. Gale, J. Wilson, J. Chia, H. Trinh, K. Tuckwell, N. Collinson, S. Dimonaco, S. Jick, C. Meier, S. Mohan, K. Sarsour |
| 2018 |
Risk factors and secondary care utilisation in a primary care population with non-tuberculous mycobacterial disease in the UK
10.1007/s10096-018-3402-8
Authors: E. Axson, N. Bual, C. Bloom, J. Quint |
| 2018 |
Risk factors for Burkitt lymphoma: a nested case-control study in the UK Clinical Practice Research Datalink
10.1111/bjh.15229
Authors: P. Karimi, B. Birmann, L. Anderson, C. McShane, S. Gadalla, J. Sampson, S. Mbulaiteye |
| 2018 |
Risk factors for influenza-related complications in children during the 2009/10 pandemic: a UK primary care cohort study using linked routinely collected data
10.1017/s0950268818000353
Authors: J. Lee, C. Bankhead, M. Smith, A. Kousoulis, C. Butler, K. Wang |
| 2018 |
Risk factors for self-harm in people with epilepsy
10.1007/s00415-018-9094-2
Authors: H. Gorton, R. Webb, W. Pickrell, M. Carr, D. Ashcroft |
| 2018 |
Risk of a first-ever acute myocardial infarction and all-cause mortality with sulphonylurea treatment: A population-based cohort study
10.1111/dom.13168
Authors: J. van Dalem, Mcgj Brouwers, C. Stehouwer, A. Krings, O. Klungel, J. Driessen, F. de Vries, A. Burden |
| 2018 |
Risk of adverse outcomes following urinary tract infection in older people with renal impairment: Retrospective cohort study using linked health record data
10.1371/journal.pmed.1002652
Authors: H. Ahmed, D. Farewell, N. Francis, S. Paranjothy, C. Butler |
| 2018 |
Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study
10.1186/s13075-018-1746-1
Authors: M. Roughley, A. Sultan, L. Clarson, S. Muller, R. Whittle, J. Belcher, C. Mallen, E. Roddy |
| 2018 |
Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study
10.1186/s12916-017-0987-1
Authors: Z. Paskins, R. Whittle, A. Sultan, S. Muller, M. Blagojevic-Bucknall, T. Helliwell, S. Hider, E. Roddy, C. Mallen |
| 2018 |
Risk of fragility fracture among patients with gout and the effect of urate-lowering therapy
10.1503/cmaj.170806
Authors: A. Sultan, R. Whittle, S. Muller, E. Roddy, C. Mallen, M. Bucknall, T. Helliwell, S. Hider, Z. Paskins |
| 2018 |
Risk of fragility fracture among patients with late-onset psoriasis: a UK population-based study
10.1007/s00198-018-4491-z
Authors: Z. Paskins, R. Whittle, Abdul Sultan, S. Muller, M. Blagojevic-Bucknall, T. Helliwell, J. Packham, S. Hider, E. Roddy, C. Mallen |
| 2018 |
The risk of fragility fractures in new users of dipeptidyl peptidase-4 inhibitors compared to sulfonylureas and other anti-diabetic drugs: A cohort study
10.1016/j.diabres.2017.12.008
Authors: J. Gamble, J. Donnan, E. Chibrikov, L. Twells, W. Midodzi, S. Majumdar |
| 2018 |
Risk of GERD-Related Disorders in Obese Patients on PPI Therapy: a Population Analysis
10.1007/s11695-018-3246-4
Authors: S. Erridge, O. Moussa, P. Ziprin, A. Darzi, S. Purkayastha |
| 2018 |
The risk of gout among patients with sleep apnea: a matched cohort study
10.1002/art.40662
Authors: M. Blagojevic-Bucknall, C. Mallen, S. Muller, R. Hayward, S. West, H. Choi, E. Roddy |
| 2018 |
Risk of Incident Osteoarthritis of the Hand in Statin Initiators: A Sequential Cohort Study
10.1002/acr.23616
Authors: T. Burkard, T. Hugle, J. Layton, R. Glynn, M. Bloechliger, N. Frey, S. Jick, C. Meier, J. Spoendlin |
| 2018 |
Risk of Infection in Type 1 and Type 2 Diabetes Compared With the General Population: A Matched Cohort Study
10.2337/dc17-2131
Authors: I. Carey, J. Critchley, S. DeWilde, T. Harris, F. Hosking, D. Cook |
| 2018 |
Risk of skin cancer among patients with myotonic dystrophy type 1 based on primary care physician data from the U.K. Clinical Practice Research Datalink
10.1002/ijc.31143
Authors: Y. Wang, R. Pfeiffer, R. Alsaggaf, W. Meeraus, J. Gage, L. Anderson, R. Bremer, N. Nikolenko, H. Lochmuller, M. Greene, S. Gadalla |
| 2018 |
Risk of type 2 diabetes and cardiovascular disease in an incident cohort of people with psoriatic arthritis: a population-based cohort study
10.1093/rheumatology/key286
Authors: R. Charlton, A. Green, G. Shaddick, J. Snowball, A. Nightingale, W. Tillett, C. Smith, N. McHugh |
| 2018 |
Risk of Unnatural Mortality in People With Epilepsy
10.1001/jamaneurol.2018.0333
Authors: H. Gorton, R. Webb, M. Carr, M. DelPozo-Banos, A. John, D. Ashcroft |
| 2018 |
Risk of uveitis and inflammatory bowel disease in people with psoriatic arthritis: a population-based cohort study
10.1136/annrheumdis-2017-212328
Authors: R. Charlton, A. Green, G. Shaddick, J. Snowball, A. Nightingale, W. Tillett, C. Smith, N. McHugh |
| 2018 |
Risk of venous thromboembolism among users of different anti-osteoporosis drugs: a population-based cohort analysis including over 200,000 participants from Spain and the UK
10.1007/s00198-017-4308-5
Authors: E. Martin-Merino, I. Petersen, S. Hawley, A. Alvarez-Gutierrez, S. Khalid, A. Llorente-Garcia, A. Delmestri, M. Javaid, T. van Staa, A. Judge, C. Cooper, D. Prieto-Alhambra |
| 2018 |
The risk of venous thromboembolism during and after hospitalisation in patients with inflammatory bowel disease activity
10.1111/apt.15010
Authors: T. Chu, M. Grainge, T. Card |
| 2018 |
Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care
10.1136/bmj.k2505
Authors: Y. Vinogradova, C. Coupland, T. Hill, J. Hippisley-Cox |
| 2018 |
Routes to diagnosis of heart failure: observational study using linked data in England
10.1136/heartjnl-2017-312183
Authors: A. Bottle, D. Kim, P. Aylin, M. Cowie, A. Majeed, B. Hayhoe |
| 2018 |
Safety of multicomponent meningococcal group B vaccine (4CMenB) in routine infant immunisation in the UK: a prospective surveillance study
10.1016/s2352-4642(18)30103-2
Authors: P. Bryan, S. Seabroke, J. Wong, K. Donegan, E. Webb, C. Goldsmith, C. Vipond, I. Feavers |
| 2018 |
Searching for a prodrome for rheumatoid arthritis in the primary care record: A case-control study in the clinical practice research datalink
10.1016/j.semarthrit.2018.06.008
Authors: S. Muller, S. Hider, A. Machin, R. Stack, R. Hayward, K. Raza, C. Mallen |
| 2018 |
Selection of men for investigation of possible testicular cancer in primary care: a large case-control study using electronic patient records
10.3399/bjgp18X697949
Authors: E. Shephard, W. Hamilton |
| 2018 |
Selective serotonin reuptake inhibitor use and breast cancer survival: a population-based cohort study
10.1186/s13058-017-0928-0
Authors: J. Busby, K. Mills, S. Zhang, F. Liberante, C. Cardwell |
| 2018 |
Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death
10.1016/s2215-0366(18)30348-1
Authors: C. Morgan, R. Webb, M. Carr, E. Kontopantelis, C. Chew-Graham, N. Kapur, D. Ashcroft |
| 2018 |
Serum potassium as a predictor of adverse clinical outcomes in patients with chronic kidney disease: new risk equations using the UK clinical practice research datalink
10.1186/s12882-018-1007-1
Authors: H. Furuland, P. McEwan, M. Evans, C. Linde, D. Ayoubkhani, A. Bakhai, E. Palaka, H. Bennett, L. Qin |
| 2018 |
Severe and predominantly active atopic eczema in adulthood and long term risk of cardiovascular disease: population based cohort study
10.1136/bmj.k1786
Authors: R. Silverwood, H. Forbes, K. Abuabara, A. Ascott, M. Schmidt, S. Schmidt, L. Smeeth, S. Langan |
| 2018 |
Severe mental illness and chronic kidney disease: a cross-sectional study in the United Kingdom
10.2147/clep.s154841
Authors: M. Iwagami, K. Mansfield, J. Hayes, K. Walters, D. Osborn, L. Smeeth, D. Nitsch, L. Tomlinson |
| 2018 |
Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data
10.2337/dc18-0344
Authors: J. Dennis, W. Henley, M. Weedon, M. Lonergan, L. Rodgers, A. Jones, W. Hamilton, N. Sattar, S. Janmohamed, R. Holman, E. Pearson, B. Shields, A. Hattersley |
| 2018 |
SGLT-2 Inhibitors and Cardiovascular Risk: An Analysis of CVD-REAL
10.1016/j.jacc.2018.01.085
Authors: M. Cavender, A. Norhammar, K. Birkeland, M. Jorgensen, J. Wilding, K. Khunti, A. Fu, J. Bodegard, B. Blak, E. Wittbrodt, M. Thuresson, P. Fenici, N. Hammar, M. Kosiborod |
| 2018 |
Short- and long-term cost and utilization of health care resources in Parkinson\textquoterights disease in the UK
10.1002/mds.27302
Authors: S. Weir, M. Samnaliev, T. Kuo, T. Tierney, Walleser Autiero, R. Taylor, A. Schrag |
| 2018 |
Smoking Status at Diagnosis and Subsequent Smoking Cessation: Associations With Corticosteroid Use and Intestinal Resection in Crohn\textquoterights Disease
10.1038/s41395-018-0273-7
Authors: C. Alexakis, S. Saxena, V. Chhaya, E. Cecil, A. Majeed, R. Pollok |
| 2018 |
Spatial distribution of clinical computer systems in primary care in England in 2016 and implications for primary care electronic medical record databases: a cross-sectional population study
10.1136/bmjopen-2017-020738
Authors: E. Kontopantelis, R. Stevens, P. Helms, D. Edwards, T. Doran, D. Ashcroft |
| 2018 |
Statin use and reduced risk of biliary tract cancers in the UK Clinical Practice Research Datalink
10.1136/gutjnl-2018-317504
Authors: Z. Liu, R. Alsaggaf, K. McGlynn, L. Anderson, H. Tsai, B. Zhu, Y. Zhu, S. Mbulaiteye, S. Gadalla, J. Koshiol |
| 2018 |
Statin use and survival in patients with gastric cancer in two independent population-based cohorts
10.1002/pds.4688
Authors: A. Spence, J. Busby, C. Hughes, B. Johnston, H. Coleman, C. Cardwell |
| 2018 |
Statin use in cancer survivors versus the general population: cohort study using primary care data from the UK clinical practice research datalink
10.1186/s12885-018-4947-8
Authors: K. Chidwick, H. Strongman, A. Matthews, S. Stanway, A. Lyon, L. Smeeth, K. Bhaskaran |
